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All Journal Biofaal Journal Rumphius Pattimura Biological Journal Balobe: Jurnal Pengabdian Masyarakat Kalwedo Sains (KASA)
Baszary, Chomsa Dintasari Umi
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Social Sciences Other

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ADMINISTRATED OF SNAKE WOOD (Strychnos lucida) TO DECREASED ABNORMALITY SPERMATOZOA OF MICE (Mus musculus) DIABETES MELLITUS MODELING Kunu, Marissa Beatrix; Baszary, Chomsa Dintasari Umi; Killay, Amos
RUMPHIUS Vol 2 No 2 (2020): RUMPHIUS Pattimura Biological Journal
Publisher : Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/rumphiusv2i2p037-042

Abstract

Diabetes mellitus, known as diabetes or blood sugar disease, is a group of chronic diseases characterized by increased blood sugar level (hyperglycemia). Prolonged hyperglycemia conditions will cause an increase in ROS (Reactive Oxygen Spesies) production by the mitochondria, which then cause damage to the mitochondrial membrane resulting in loss of function of the mitochondrial membrane potential and can induce sperm cells apoptosis. This study aims to determine effect of kayu ular (Strychnos lucida) steeping on decreasing spermatozoa abnormalities of mice (Mus musculus) diabetes mellitus model. The result showed that administration of kayu ular steeping at concentration of 2,6gr/50ml was signicantly reduced (P<0.05) spermatozoa abnormality. This dose is the most effective concentration to decreased the spermatozoa abnormality of mice. This though to be due to the active compounds found in steeping kayu ular (Strychnos lucida) which can counteract free radicals due to diabetes mellitus that decreasing spermatozoa abnormalities.
Efek Antidiabetes Yoghurt Pala Terhadap Penurunan Kadar Glukosa Darah Tikus Model Diabetes Melitus Tipe 2 Unitly, Adrien Jems Akiles; Baszary, Chomsa Dintasari Umi; Moniharapon, Debby D.; Watuguly, Theopilus W.; Moniharapon, Mechiavel; Eddy, La; Lesbatta, Kezia Josawel; Sillehu, Eka Safitri; Sikafir, Beatrix Belina; Sopacua, Gracia N.
Kalwedo Sains (KASA) Vol 5 No 2 (2024): Kalwedo Sains (KASA), September 2024
Publisher : Program Studi Di Luar Kampus Utama Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/kasav5i2p91-98

Abstract

Diabetes Melitus tipe 2 adalah penyakit gangguan metabolik yang di tandai oleh kenaikan gula darah akibat penurunan sekresi insulin oleh sel beta pankreas atau gangguan fungsi insulin (resistensi insulin). Potensi yoghurt dalam menurunkan kadar glukosa darah berhubungan dengan kemampuan bakteri asam laktat dalam yoghurt menurunkan kadar kolesterol dan plasma lipid, sehingga meningkatkan sensitivitas insulin pankreas. Buah pala mengandung senyawa kimia yang dapat menunjukkan sifat antioksidan dan antibakteri. Tujuan penelitian ini untuk mengetahui efek terapi yoghurt pala terhadap penurunan kadar glukosa darah tikus model diabetes melitus tipe 2. Penelitian ini menggunakan rancangan acak lengkap (RAL). Penelitian ini menggunakan rancangan acak lengkap (RAL) yang terdiri dari lima perlakuan dan tiga kali ulangan, yaitu K(-): Kelompok kontrol negatif yaitu kelompok tikus yang diberi STZ, K(+): Kelompok kontrol positif yaitu kelompok tikus yang diberi STZ 45 mg/ekor/hari kemudian diberikan obat glibenklamid selama 14 hari, 1.25: Kelompok tikus yang diberi STZ 45 mg /ekor/hari kemudian diberi ekstrak yoghurt pala 1.25 ml /ekor/hari selama 14 hari, 2.5: Kelompok tikus yang diberi STZ 45 mg /ekor/hari kemudian diberi ekstrak yoghurt pala 2.5 ml/ekor/hari selama 14 hari dan 5.0: Kelompok tikus yang diberi STZ 45 mg /ekor/hari kemudian diberi ekstrak yoghurt pala 5 ml/ekor/hari selama 14 hari. Hasil penelitian menunjukkan pemberian yoghurt pala terbukti memiliki efek antioksidan dalam menurunkan kadar glukosa darah dimana dosis yoghurt pala yang efektif adalah 5.0 ml.
PEMANFAATAN BUAH MANGROVE (Sonneratia caseolaris) MENJADI SABUN CAIR ANTISEPTIK DI DESA ALLANG ASAUDE Patty, Kristi Lenci; Nusaly, Windy Natalia; Huwae, Laury Marcia Chara; Mose, Windi; Baszary, Chomsa Dintasari Umi
Balobe: Jurnal Pengabdian Masyarakat Vol 3 No 2 (2024): Balobe: Jurnal Pengabdian Masyarakat
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/balobe.3.2.108-112

Abstract

Alang Asaode Village is one of the villages in West Seram Regency that has a large mangrove forest. Sonneratia caseolaris is one type of mangrove that has a fruit called pedada fruit. Pedada fruit has nutritional content that can be utilized into food products such as jam and syrup because of its high vitamin C content and can also be processed into antiseptic liquid soap. Community service activities in Alang Asaode village in the form of socialization of pedada fruit processing using the fermentation process into economically valuable products such as liquid soap to increase family income.
Effectiveness of Methanol and Petroleum Benzene Extracts of Catharantus roseus Leaves in Reducing Blood Sugar Levels in Mice (Mus musculus) Diabetes Mellitus Model Siscawati, Winda; Baszary, Chomsa Dintasari Umi
Biofaal Journal Vol 6 No 1 (2025): Biofaal Journal
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/biofaal.v6i1pp47-59

Abstract

Catharanthus roseus, a plant belonging to the Apocynaceae family, contains various chemical compounds. The roots, stems, leaves, and seeds of Catharanthus roseus contain over 70 types of alkaloids, including 28 bi-indole alkaloids found throughout the plant. These compounds, many of which are beneficial in medicine, exhibit blood sugar-lowering (hypoglycemic) properties. This study aims to evaluate the effects of pure methanol extracts of Catharanthus roseus leaves on diabetes mellitus in mice, providing comprehensive evidence of its efficacy. Methanol and petroleum benzene extracts of Catharanthus roseus leaves were diluted to a 5% concentration and administered to test animals at a dose of 1.5 ml. After a two-week testing period, the results showed a significant reduction in blood sugar levels in the diabetes mellitus model mice. This demonstrates the hypoglycemic effect of methanol and petroleum benzene extracts of Catharanthus roseus leaves in lowering blood glucose levels in streptozotocin-induced mice.
PENGARUH LAMA PENGERINGAN PADA AMPAS DAGING BUAH PALA (Myristica fragrans Houtt) SEBAGAI NUTRICEUTICAL TEH PALA Baszary, Chomsa Dintasari Umi
Biofaal Journal Vol 3 No 1 (2022): Biofaal Journal
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/biofaal.v3i1pp28-32

Abstract

Penelitian ini bertujuan untuk mengetahui kadar air ampas pala dengan lama pengeringan satu jam, dua jam, tiga jam, dan empat jam sebagai minuman nutriceutical yang baik untuk kesehatan.parameter pengamatan adalah kandungan senyawa aktif fenol. Flavonoid, miristisin, dan antioksidan.
Organoleptic Test of Nutmeg Pulp Residue Tea (Myristica fragrans Houtt) As a Nutriceutical Baszary, Chomsa Dintasari Umi; Sahertian, Dece Elisabeth
Biofaal Journal Vol 6 No 2 (2025): Biofaal Journal
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/biofaal.v6i2pp141-148

Abstract

Nutmeg (Myristica fragrans Houtt) is a native Indonesian spice, and its pulp is often discarded as waste after juice production. However, the residue still contains essential oils and active compounds such as flavonoids, phenols, and myristicin, which may benefit human health. This study aims to evaluate the potential of nutmeg pulp residue as a nutraceutical herbal tea through organoleptic testing, assessing aroma, taste, clarity, and color. The research employed a completely randomized design with three replications. Organoleptic and hedonic tests were carried out on 25 panelists using Friedman and Wilcoxon tests. Results showed that tea clarity scored highest in preference (3.72), followed by aroma (2.28), taste (2.18), and color (1.82). The nutmeg pulp tea was generally acceptable, although improvements in color and flavor intensity are needed. This innovation offers an ecological and economic solution for waste utilization, with potential for rural product diversification and health benefits.
Co-Authors Adrien Jems Akiles Unitly Amos Killay Kunu, Marissa Beatrix La Eddy LAURY CHARA HUWAE Lesbatta, Kezia Josawel Moniharapon, Debby D. Moniharapon, Mechiavel Mose, Windi Nusaly, Windy Natalia Patty, Kristi Lenci Sahertian, Dece Elisabeth Sikafir, Beatrix Belina Sillehu, Eka Safitri Siscawati, Winda Sopacua, Gracia N. Theopilus W Watuguly