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Journal : Biofaal Journal

Effectiveness of Methanol and Petroleum Benzene Extracts of Catharantus roseus Leaves in Reducing Blood Sugar Levels in Mice (Mus musculus) Diabetes Mellitus Model Siscawati, Winda; Baszary, Chomsa Dintasari Umi
Biofaal Journal Vol 6 No 1 (2025): Biofaal Journal
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/biofaal.v6i1pp47-59

Abstract

Catharanthus roseus, a plant belonging to the Apocynaceae family, contains various chemical compounds. The roots, stems, leaves, and seeds of Catharanthus roseus contain over 70 types of alkaloids, including 28 bi-indole alkaloids found throughout the plant. These compounds, many of which are beneficial in medicine, exhibit blood sugar-lowering (hypoglycemic) properties. This study aims to evaluate the effects of pure methanol extracts of Catharanthus roseus leaves on diabetes mellitus in mice, providing comprehensive evidence of its efficacy. Methanol and petroleum benzene extracts of Catharanthus roseus leaves were diluted to a 5% concentration and administered to test animals at a dose of 1.5 ml. After a two-week testing period, the results showed a significant reduction in blood sugar levels in the diabetes mellitus model mice. This demonstrates the hypoglycemic effect of methanol and petroleum benzene extracts of Catharanthus roseus leaves in lowering blood glucose levels in streptozotocin-induced mice.
PENGARUH LAMA PENGERINGAN PADA AMPAS DAGING BUAH PALA (Myristica fragrans Houtt) SEBAGAI NUTRICEUTICAL TEH PALA Baszary, Chomsa Dintasari Umi
Biofaal Journal Vol 3 No 1 (2022): Biofaal Journal
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/biofaal.v3i1pp28-32

Abstract

Penelitian ini bertujuan untuk mengetahui kadar air ampas pala dengan lama pengeringan satu jam, dua jam, tiga jam, dan empat jam sebagai minuman nutriceutical yang baik untuk kesehatan.parameter pengamatan adalah kandungan senyawa aktif fenol. Flavonoid, miristisin, dan antioksidan.
Organoleptic Test of Nutmeg Pulp Residue Tea (Myristica fragrans Houtt) As a Nutriceutical Baszary, Chomsa Dintasari Umi; Sahertian, Dece Elisabeth
Biofaal Journal Vol 6 No 2 (2025): Biofaal Journal
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/biofaal.v6i2pp141-148

Abstract

Nutmeg (Myristica fragrans Houtt) is a native Indonesian spice, and its pulp is often discarded as waste after juice production. However, the residue still contains essential oils and active compounds such as flavonoids, phenols, and myristicin, which may benefit human health. This study aims to evaluate the potential of nutmeg pulp residue as a nutraceutical herbal tea through organoleptic testing, assessing aroma, taste, clarity, and color. The research employed a completely randomized design with three replications. Organoleptic and hedonic tests were carried out on 25 panelists using Friedman and Wilcoxon tests. Results showed that tea clarity scored highest in preference (3.72), followed by aroma (2.28), taste (2.18), and color (1.82). The nutmeg pulp tea was generally acceptable, although improvements in color and flavor intensity are needed. This innovation offers an ecological and economic solution for waste utilization, with potential for rural product diversification and health benefits.