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The RATIONALITY OF USE ACYCLOVIR IN PERMATA PERMATA CLINIC, TANGERANG SELATAN CITY, JUNE-DECEMBER 2020 PERIOD: RASIONALITAS PENGGUNAAN OBAT ACYCLOVIR DI KLINIK INSAN PERMATA KOTA TANGERANG SELATAN PERIODE JUNI-DESEMBER 2020 Sayyidah, Sayyidah; Aulia , Gina; Kristiyowati , Anis Dwi
Jurnal Kesehatan Masa Depan Vol 1 No 1 (2022): Jurnal Kesehatan Masa Depan
Publisher : Ruang Ide Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58516/jkmd.v1i1.6

Abstract

Abstract Rationality of Drug Use is the administration of drugs that refers to the right diagnosis, the right indication, the right drug, the right dose, the right manner of giving and the right old proper gifts. Acyclovir is a synthetic purine nucleoside analogue drug. The antiviral properties of acyclovir are limited to the herpes virus group as well as mechanism of action is selectively. The purpose of this study was to determine know patient age, gender doctor diagnosis, the type of availability of prescription drugs acyclovir, the rationality based on the accuracy of the diagnosis, the accuracy indication, the accuracy of the drug, the accuracy of the dose, the accuracy manner of giving and the accuracy old proper gift. The design of this research is descriptive, namely research by observing the data that is already available with a descriptive method design. The data was obtained from tracing medical record data using a retrospective and total samplingThe sample of this study was 80 taken from Medical Records in June-December 2020 to be analyzed descriptively to explain the rationality of use acyclovir drug. Based on the results of research from the Insan Permata Clinic, it was found who used acyclovir drug were predominantly male, with 50 patients with a percentage of 62.5% while in women around 30 patients with a percentage of 37.5%. using acyclovir drug experienced by pediatric patients aged 6-17 years with 29 patients for the percentage there were 0.03625%. This is in accordance with the theory that infections often occur more severely in toddlers and children than adults. This is due to the immature immune system at a young age. Keywords: Acyclovir, Antivirus, Rational
UJI EFEKTIVITAS SERUM EKSTRAK DAUN KELOR (Moringa oleifera L.) SEBAGAI ANTIJERAWAT Staphylococcus aureus Dewi, Bheta Sari; Werawati, Ayu; Hasanah, Uswatun; Sayyidah, Sayyidah; Dewantoro, Agung; Saputra, Aldi
Edu Masda Journal Vol 9, No 1 (2025): EDU MASDA JOURNAL
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v9i1.281

Abstract

                                                       ABSTRACTAcne is among the most prevalent dermatological issues caused by the bacterium Staphylococcus aureus. Moringa leaf extract (Moringa oleifera L.) is known to contain bioactive compounds such as flavonoids, tannins, and alkaloids, which serve as anti-acne agents. This research seeks to assess the efficacy of a serum formulated with moringa leaf extract in inhibiting the growth of acne-causing Staphylococcus aureus. The extraction of moringa leaves was carried out using the maceration technique with 96% ethanol serving as the solvent. The extract was then formulated into a serum preparation with concentrations of 4%, 7%, and 10%, using Clindamycin as the positive control and the serum base as the negative control. The antibacterial efficacy was evaluated through the agar well diffusion technique to determine the inhibition zone against Staphylococcus aureus. Each treatment was conducted in triplicate. Additionally, the physical stability of the serum was assessed, covering organoleptic characteristics, homogeneity, pH, spreadability, and adhesion. The findings revealed that moringa leaf extract exhibited inhibitory effects on the growth of Staphylococcus aureus, as evidenced by the presence of inhibition zones. The inhibition zone diameters were 14.21 mm at 4% concentration, 17.30 mm at 7%, and 19.20 mm at 10%. In comparison, the positive control showed a diameter of 30.78 mm, while the negative control showed no inhibition (0 mm). This research suggests that serum formulated with moringa leaf extract holds promise as an effective topical solution for treating acne.                                                  ABSTRAKJerawat ialah satu diantara masalah kulit yang umum disebabkan oleh bakteri Staphylococcus aureus. Ekstrak daun kelor (Moringa oleifera L.) dikenal punya senyawa bioaktif seperti flavonoid, tanin, dan alkaloid sebagai agen antijerawat. Kajian ini memiliki tujuan guna melakukan uji efektivitas serum berbahan dasar ekstrak daun kelor dalam menghambat pertumbuhan bakteri jerawat Staphylococcus aureus. Ekstrak daun kelor diperoleh lewat metode maserasi dengan pelarut etanol 96%. Ekstrak ini kemudian diformulasi ke sediaan serum dengan konsentrasi 4%, 7%, dan 10% serta digunakan Clindamycin sebagai kontrol positif dan basis serum menjadi kontrol negatif. Uji aktivitas antibakteri memakai metode difusi sumuran agar, guna mengukur zona hambat pada Staphylococcus aureus. Perlakuan diulang sebanyak 3 kali. Stabilitas fisik serum juga diuji meliputi organoleptis, homogenitas, pH, daya sebar dan daya lekat. Hasilnya diperoleh bahwa ekstrak daun kelor mempunyai kemampuan menghambat pertumbuhan Staphylococcus aureus bisa diamati dengan adanya zona hambat yang dibentuk. Diameter zona hambat di konsentrasi 4% senilai 14,21 mm, konsentrasi 7% sebesar 17,30 mm, konsentrasi 10% senilai 19,20 mm, kontrol positif senilai 30,78 mm, dan kontrol negatif sebesar 0 mm. Kajian ini memberi indikasi jika serum ekstrak daun kelor punya potensi jadi sediaan topikal yang efektif bagi pengobatan jerawat.
Pengaruh Kompetensi dan Penempatan Kerja Terhadap Pelayanan Dengan Profesionalisme Pada Badan Kepegawaian dan Pengembangan Sumber Daya Manusia Kabupaten Tanah Bumbu Sayyidah, Sayyidah; Budhi, Setia
Jurnal Ilmiah Muqoddimah: Jurnal Ilmu Sosial, Politik dan Hummaniora Vol 8, No 2 (2024): Mei 2024
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jim.v8i2.2024.888-896

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh Kompetensi dan Penempatan Kerja terhadap Pelayanan dengan Profesionalisme pada Badan Kepegawaian dan Pengembangan Sumber Daya Manusia Kabupaten Tanah Bumbu. Penelitian ini dilakukan dengan pendekatan kuantitatif dengan metode explanatory research. Hasil penelitian menunjukkan bahwa 1) Kompetensi memiliki nilai thitung 1,267 ttabel 2,010 dengan taraf signifikan 0,212 0,05 maka kompetensi tidak memiliki pengaruh parsial dan tidak signifikan terhadap pelayanan pada BKPSDM Kabupaten Tanah Bumbu. 2) Penempatan Kerja memiliki nilai thitung 2,550 ttabel 2,010 dengan taraf signifikan 0,014 0,05 maka penempatan kerja memiliki pengaruh parsial dan signifikan terhadap pelayanan pada BKPSDM Kabupaten Tanah Bumbu. 3) Profesionalisme memiliki nilai thitung 4,341 ttabel 2,010 dengan taraf signifikan yaitu 0,000 0,05 maka profesionalisme memiliki pengaruh parsial dan signifikan terhadap pelayanan BKPSDM Kabupaten Tanah Bumbu. 4) Kompetensi dan penempatan kerja memiliki nilai Fhitung 5,707 Ftabel3,20 dengan taraf signifikan 0,006 0,05 maka kompetensi dan penempatan kerja memiliki pengaruh simultan dan signifikan terhadap profesionalisme pada BKPSDM Kabupaten Tanah Bumbu. 5) Kompetensi melalui profesionalisme memiliki nilai thitung 1,6878 ttabel 2,010 maka kompetensi tidak memiliki pengaruh terhadap pelayanan melalui profesionalisme pada BKPSDM Kabupaten Tanah Bumbu. 6) Penempatan kerja melalui profesionalisme memiliki nilai thitung 3,7968 ttabel 2,010 maka penempatan kerja memiliki pengaruh terhadap pelayanan melalui profesionalisme pada BKPSDM Kabupaten Tanah Bumbu.   
THE COMMUNITY SERVICE EDUCATION ABOUT REPRODUCTIVE HEALTH IN YOUTH: PENGABDIAN KEPADA MASYARAKAT PENYULUHAN MENGENAI KESEHATAN REPRODUKSI PADA REMAJA Rohanah, Rohanah; Sayyidah, Sayyidah
Jurnal Pengabdian Masyarakat Kesehatan Terkini Vol 1 No 1 (2022): Jurnal Pengabdian Masyarakat Kesehatan Terkini
Publisher : Ruang Ide Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58516/jpmkt.v1i1.11

Abstract

Abstract Teenager is a stage between childhood and adulthood. Adolescence, also known as puberty, is a time between childhood and adulthood. In the life cycle of puberty is an important stage in the development of sexuality. Extension is a form of non-formal education effort to individuals or community groups that is carried out in a systematic, planned and directed manner in an effort to change sustainable behavior in order to achieve increased production, income and welfare improvements. The goal is to increase the knowledge of Adolescents there are Information and Challenges of Reproductive Health in Adolescents so that they can behave in a healthy manner. The result of this activity is the high interest and awareness of participants to participate in health education. Increase participants' knowledge about the importance of maintaining healthy reproductive health in adolescence, Increased awareness of participants to empower themselves in healthy adolescent relationships. Keywords: teenager, reproduction, counseling
EVALUASI PENGELOLAAN OBAT RUSAK, OBAT EXPIRED DATE DAN OBAT DEAD STOCK DI APOTEK “X” KOTA TANGERANG SELATAN TAHUN 2023 Rahajeng, Suny Koswara; Kristiyowati, Anis Dwi; Listiana, Ida; Sayyidah, Sayyidah; Haryani, Setianti; Ismaya, Nurwulan Adi
PHRASE (Pharmaceutical Science) Journal Vol 5, No 1 (2025): Vol 5 No 1 : Pharmaceutical Science Journal
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i1.914

Abstract

Latar belakang: Pengelolaan obat merupakan serangkaian proses perencanaan, pengadaan, penerimaan, penyimpanan, pemusnahan, pengendalian dan pencatatan serta pelaporan. Jika pengelolaan tidak dilakukan dengan benar maka akan timbul beberapa masalah di antaranya obat rusak yaitu obat yang mengalami kerusakan pada fisik, obat expired date adalah obat yang sudah melewati batas expired date yang tertera pada kemasan dan obat dead stock yaitu obat yang selama 3 bulan tidak terdapat transaksi hal – hal yang akan menimbulkan kerugian. Penyebabnya karena pengelolaan obat yaitu penyimpanan dan pengadaan. Sehingga obat menjadi rusak sebelum waktu expired date dan stok obat mengalami penumpukan akibat pengadaan dan sistem yang kurang tepat. Oleh karena itu tempat penyimpanan obat harus sesuai denganstandar agar pelayanan obat dapat berjalan dengan baik. Tujuan: untuk mengetahui melalui persentase obat rusak, obat expired date dan dead stock. Metode penelitian: Penelitian ini menggunakan deskriptif menggunakan pendekatan kuantitatif serta pengambilan data secara retrospektif. Data yang dikumpulkan menggunakan lembar observasi kemudian diolah dengan menggunakan microsoft excel setelah itu data diukur sesuai dengan indikator. Hasil: Penelitian menunjukkan persentase obat rusak 0,5% , obat expired date 2,1% dan obat dead stock sebesar 18%. Dari hasil tersebut tingkat pengelolaan obat yang kurang baik terutama pada perencanaan dan pengadaan serta penyimpanan yang belum baik karena masih melebihi nilai indikatornya yaitu 0%. Maka dapat lebih diperhatikan untuk penyusunan, penyimpanan dan pengadaan obat di Apotek.
PENGARUH EDUKASI GIZI DENGAN MEDIA KOMIK TERHADAP TINGKAT PENGETAHUAN DAN SIKAP REMAJA TENTANG ANEMIA Wijaya, Rafika Dora; Betty, Betty; Alifia, Eva Putri; Sayyidah, Sayyidah
Edu Dharma Journal :Jurnal penelitian dan pengabdian masyarakat Vol 9, No 1 (2025): Edu Dharma Journal: Jurnal Penelitian Dan Pengabdian Masyarakat
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/edj.v9i1.1080

Abstract

                                               ABSTRACTBackground: World Health Organization (WHO) data (2021) shows that the prevalence of anemia in adolescent girls is around 30%. Meanwhile, data on anemia in adolescent girls (rematri) in Indonesia shows 72.3%. The majority of anemia in rematri (84.6%) is in the age range of 15-24. Adolescents are a group that is vulnerable to health risks caused by various complex problems in adolescents and their lack of information and knowledge. Objective: The study aims to determine the effect of nutrition education with comic media on the level of knowledge and attitudes about anemia in adolescents at MTS YAPINA. Method: This study is a quantitative study using a pre-experimental method with a one-group pre-test post-test design. The instrument in this study used a questionnaire made in the form of Google Forms. The number of samples was 137 MTS YAPINA female students, with a sampling technique of non-probability sampling with a total sampling method. Results: The results showed that the average value of students' knowledge before nutrition education was 9.00. Then, after health education was carried out, the average value increased to 713.15. The average value of attitudes before nutrition education was 19.93 and increased to 25.80 and a p-value of 0.001 ≤ 0.05 was obtained. Conclusion: Nutrition education with comic media affects the level of knowledge and attitudes about anemia in adolescents at MTS Yapina. Suggestion: Rematri are expected to maintain the knowledge and attitudes they already have and apply good behavior regarding a balanced diet in everyday life to prevent anemia.                                                    ABSTRAK Latar belakang: Data World Health Organization (WHO) (2021) menunjukkan bahwa prevalensi anemia pada remaja putri sekitar 30%. Sedangkan data Anemia pada remaja putri (rematri) di Indonesia menunjukkan sebesar 72,3%. Mayoritas Anemia pada rematri (84,6 %) berada pada rentang usia 15-24. Remaja merupakan kelompok yang rentan terhadap risiko kesehatan yang disebabkan oleh berbagai permasalahan yang komplek pada remaja serta informasi dan pengetahuan mereka yang masih kurang. Tujuan: Penelitian bertujuan untuk mengetahui pengaruh edukasi gizi dengan media komik terhadap tingkat pengetahuan dan sikap tentang anemia pada remaja di MTS YAPINA. Metode: Penelitian ini merupakan penelitian kuantitatif dengan menggunakan metode pre eksperiment dengan rancangan one grup pre test post test design. Instrument dalam penelitian ini menggunakan kuesioner yang dibuat dalam bentuk google form. Jumlah sampel sebanyak 137 siswi MTS YAPINA, dengan teknik pengambilan sampel yaitu non-probability sampling dengan metode total sampling. Hasil: hasil menunjukkan diperoleh rata-rata nilai pengetahuan siswi sebelum dilakukan edukasi gizi adalah 9,00 Kemudian susudah dilakukan edukasi kesehatan rata-rata nilainya meningkat menjadi 713,15. Nilai rata-rata sikap sebelum dilakukan edukasi gizi adalah 19,93 dan meningkat menjadi 25,80 dan diperoleh nilai p-value yaitu 0,001 ≤ 0,05. Kesimpulan: terdapat pengaruh edukasi gizi dengan media komik terhadap tingkat pengetahuan dan sikap tentang anemia remaja di MTS Yapina. Saran: Rematri diharapkan dapat mempertahankan pengetahuan dan sikap yang sudah dimiliki dan menerapkan perilaku yang baik mengenai pola makan seimbang dalam kehidupan sehari-hari untuk mencegah anemia. 
Formulation and Antioxidant Activity of Syrup Preparation Containing Saga Leaf Extract (Abrus precatorius L.) Dewi, Bheta Sari; Utami, Sheila Meitania; Sayyidah, Sayyidah; Alamsyah, Salwa Season; Rahmadani, Novita Tri
Jurnal Kefarmasian Indonesia VOLUME 15, NUMBER 1, FEBRUARY 2025
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Saga leaf (Abrus precatorius L.) have tannins, saponins, alkaloids, and flavonoids that have functions as antioxidants. The plant belongs to the Fabaceae family and is widespread in the tropics and subtropics. Syrup is one form of pharmaceutical preparation used in providing drugs in liquid form so that it is easily drunk by patients, especially children. The purpose of this study was to obtain the best syrup preparation formulation physically and its antioxidant activity. Saga leaf are extracted in ethanol and then syrup preparations by adding saga leaf extract with concentration variations of 0.5% (FI), 1% (FII), and 2% (FIII). Evaluation of syrup preparations includes organoleptic, pH, homogeneity, and antioxidant activity test using DPPH (1,1-diphenyl-2-picrylhydrazyl) measured by UV-Vis spectrophotometer at wavelength 516 nm. The results showed that Formula III had the best results, namely clear dark brown organoleptic, slightly viscous shape, distinctive smell and slightly bitter taste, pH 6.15, homogeneous, and the preparation was stable in storage for 12 days and showed the best IC50 value of 116.94 g/mL compared to FI (132.65 g/mL) and FII (118.03 g/mL). The antioxidant activity of saga leaf extract is categorized as moderate. In conclusion, saga leaf can be formulated as a syrup preparation with an extract concentration of 2% in formula III showing effectiveness as the best IC50 value of 116.94 g/mL and the best formulation.