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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Analis Medika Biosains (JAMBS) Indonesian Health Issue Jurnal Teknologi Laboratorium Medik Borneo Journal of Indonesia Laboratory Students (JILTS)
I Wayan Getas
Poltekkes Kemenkes Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Veterinary

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Association Between Blood Glucose Levels and Platelet Indices in Patients with Type 2 Diabetes Mellitus Thomas Tandi Manu; Ida Bagus Rai Wiadnya; I wayan Getas
Indonesian Health Issue Vol. 5 No. 2 (2026): AUGUST
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/inhis.v5i2.214

Abstract

Background: Platelet activity in diabetes mellitus is a concern because platelets play a role in thrombus formation and atherothrombosis. Platelet activity can be assessed through platelet indices, which include the Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), Plateletcrit (PCT), and Platelet Large Cell Ratio (P-LCR), providing an indirect reflection of platelet characteristics. Changes in these parameters may be associated with an increased risk of cardiovascular complications in patients with diabetes mellitus. Objective: This study aims to evaluate platelet activity and analyze its relationship with blood glucose levels in patients with diabetes mellitus. Methods: This study employed an analytical observational design with a cross-sectional approach. The sample consisted of 50 patients with type 2 diabetes mellitus participating in the Chronic Disease Management Program (Prolanis) at the Praya Community Health Center, selected through purposive sampling. Data on blood glucose levels and platelet indices were analyzed using Pearson’s correlation test. Results: The examination results showed a mean blood glucose level of 148.42 mg/dL. Meanwhile, the mean platelet indices were as follows: PDW 16.1%; MPV 9.59 fL; P-LCR 24.43%; and PCT 2.6 mL/L. The results of the Pearson correlation test showed that blood glucose levels were correlated with PDW (r = 0.131; p = 0.364), PCT (r = 0.148; p= 0.305), P-LCR (r = 0.213; p=0.138), and MPV (r=0.182; p=0.206). Conclusion: Platelet indices in patients with diabetes mellitus were generally within the normal range. Blood glucose levels showed a tendency toward a positive correlation with platelet indices, but no  statistically significant relationship was found
Inhibition Test of Honey Mango Leaf Extract (Mangivera Indica L.) against the Growth of Aspergillus flavus Lestari Febriani; I Wayan Getas; Thomas Tandi Manu; Erna Kristinawati
Journal of Indonesia Laboratory Students (JILTS) Vol. 5 No. 2 (2026): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v5i2.466

Abstract

Background: Aspergillus flavus is a dangerous pathogenic contaminant in agricultural commodities capable of producing highly carcinogenic aflatoxins. The escalation of resistance against synthetic chemical antifungals necessitates the discovery of safer natural alternatives. Honey mango leaves (Mangifera indica L. var. madu) accumulate potent secondary metabolites including flavonoids, tannins, saponins, alkaloids, and phenolics that manifest high antimicrobial properties. Objective: To determine the inhibitory effect of honey mango leaf (Mangifera indica L.) extract at concentrations of 80%, 70%, 60%, 50%, 40%, 30%, and 20% on the growth of Aspergillus flavus. Research Methods: This laboratory experimental design employed the disc diffusion technique using seven concentration levels (80%, 70%, 60%, 50%, 40%, 30%, and 20%) with triplicated observations. The primary metric recorded was the diameter of the inhibition zone around the paper discs. Research Results: The organic extract significantly restricted the proliferation of Aspergillus flavus across all tested ranges. The mean diameter of inhibition zones for concentrations of 80%, 70%, 60%, 50%, 40%, 30%, and 20% were measured at 39.3 mm, 33.7 mm, 31.3 mm, 26.0 mm, 24.7 mm, 20.7 mm, and 17.0 mm, respectively. Statistical trends confirmed that the inhibition area expands proportionally with the increase of extract dose. Conclusion: Honey mango leaf extract exhibits robust antifungal activities. A concentration of 50% represents the optimum threshold, yielding an inhibitory zone of 26.0 mm which demonstrates clinical parity with the commercial positive control group.
Co-Authors Agrijanti, Agrijanti Baiq Isni Amalia Dewi, Lale Budi Kusuma Erlin Yustin Tatontos Erna Kristinawati Ershandi Resnhaleksmana Eva Royandriani Rustamaji Hani Laili Katari Hikmatul Lailli Khairal Yasmin Lalu Srigede Lestari Febriani Lisda Ramadhania Miftahul Jannah Musayadah Musayadah Ni Kadek Ayu Parweni Ni Luh Gita Gandi Nispahayati Nispahayati RAI WIADNYA, IDA BAGUS Rohmi Rohmi Siti zaetun Thomas Tandi Manu Urip Urip