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All Journal Jurnal Riset Kimia Jurnal Pengabdian UntukMu NegeRI Lantanida Journal ALCHEMY Jurnal Penelitian Kimia Indonesian Journal of Chemistry JURNAL PHOTON Molekul: Jurnal Ilmiah Kimia Acta Chimica Asiana Jurnal Pengabdian kepada Masyarakat Nusantara Makara Journal of Science Mestaka: Jurnal Pengabdian Kepada Masyarakat Molekul: Jurnal Ilmiah Kimia Jurnal Kesehatan Masyarakat
Jufrizal Syahri
Department Of Chemistry, Faculty Of Mathematics And Natural Sciences, Universitas Muhammadiyah Riau, Pekanbaru 28156, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Energy Environmental Science Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Nursing Physics Public Health Social Sciences Other

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Workshop Sertifikasi Pranata Laboratorium Untuk Guru Sains Tingkat SLTA Se-Provinsi Riau Siregar, Sri Hilma; Prasetya, Prasetya; Nasution, Hasmalina; Hilma, Rahmiwati; Perdana, Fitra; Syafri, Rahmadini; Syahri, Jufrizal
Jurnal Pengabdian UntukMu NegeRI Vol. 7 No. 1 (2023): Pengabdian Untuk Mu negeRI
Publisher : LPPM UMRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jpumri.v7i1.4932

Abstract

Saat ini banyak sekolah tingkat SLTA se-Provinsi Riau dan sekitarnya tidak memiliki pranata laboratorium pendidikan yang berkompeten dibidangnya. Hal ini menyebabkan banyak sekolah yang memiliki laboratorium tapi tidak digunakan secara maksimal, dan siswa siswi tidak dapat melaksanakan praktikum yang semestinya di laboratorium. Laboratorium hanya menjadi tempat pajangan alat peraga dan instrumentasi. Berdasarkan hal tersebut, kami merasa perlu memfasilitasi para pranata laboratorium pendidikan dengan memberikan pelatihan pengelolaan dan penggunaan laboratorium untuk praktikum siswa siswi di sekolah. Sehingga dihasilkan lulusan yang berkompeten. Kegiatan dirancang dalam bentuk pengembangan wawasan keilmuan melalui pemberian berbagai teori selama 2 hari dan dilanjutkan dengan praktik dan penugasan pada 2 hari berikutnya. Materi yang diberikan kepada peserta diantaranya tentang inovasi hasil penelitian, pengenalan dan pengelolaan laboratorium, praktikum ciri-ciri reaksi kimia, hokum kekekalan massa, reaksi zat makanan. pemahaman dan kemampuan guru terhadap materi pelatihan, yang nantinya dapat digunakan sebagai acuan dalam melaksanakan praktikum di laboratorium sekolah. Kegiatan workshop ini mendapat sambutan yang baik dari peserta dan berhasil dengan baik. Keadaan ini dapat dilihat dari kehadiran peserta yang hampir mencapai 100%. Peserta terdiri guru dan pranata laboratrium pendidikan ingkat SLTA se-Provinsi Riau.
Pembuatan Nugget Dari Biji Nangka Upaya Mengoptimalkan Sumber Daya Masyarakat Desa Kualu Nenas Nasution, Hasmalina; Putri, Rahmayani Indah; Hidayati, Retno; Prasetya, Prasetya; Perdana, Fitra; Syafri, Rahmadini; Syahri, Jufrizal; Hilma, Rahmiwati; Siregar, srihilma; Ramadhanti, Aulia Rizki
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 4 No. 4 (2023): Jurnal Pengabdian kepada Masyarakat Nusantara (JPkMN)
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kualu Nenas Village is a village that produces quite a lot of jackfruit flesh in the form of chips for sale. UMKM that process jackfruit as the main ingredient will have an impact on the amount of easily damaged organic solid waste from the jackfruit itself, such as jackfruit seeds. However, in processing jackfruit seeds are more often just boiled or fried as a snack. One way to process jackfruit seed waste is to make nuggets. Socialization and nugget making training activities were carried out in Kualu Nenas Village with the PPK Ormawa HIMAKI team. The aim of this activity is to increase knowledge and skills for the people of Kualu Nenas Village in processing waste, optimizing natural resources, and improving the community's economy by selling jackfruit seed nuggets. The activity began with a presentation through socialization of material about waste jackfruit seeds and nuggets in general, then continued with practical training in making nuggets from waste jackfruit seeds. The results obtained from this community service activity are that the community can understand the techniques for processing jackfruit seed waste into nuggets well as shown by the achievement percentage ≤ 74%.
Studi Molecular Docking dan Evaluasi Farmakokinetik Senyawa Analog Pirazol Turunan Benzen-Sulfonilurea sebagai Inhibitor Enzim Aldose Reduktase and α-Glukosidase Menggunakan Pendekatan In Silico Fatisa, Yuni; Utami, Lisa; Syahri, Jufrizal; Jasril, Jasril; Lazulva, Lazulva
Jurnal Riset Kimia Vol. 15 No. 2 (2024): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v15i2.633

Abstract

The pyrazole scaffold modification in various chemical structures on several studies has shown various biopharmacological activities. This study aims to predict the potential inhibition of pyrazole analogs derived benzene-sulfonylurea (4A, 4B, 4E, 5A, 5C, 5D) against the α-glucosidase (3A4A) and aldose reductase (3RX2) enzymes based on a molecular docking approach using Molecular Operating Environment (MOE) 2020.0102 software and evaluate pharmacokinetic profile (ADMET). In this study, the six test compounds were obtained from previous studies that have been proven antihyperglycemic. The results showed that all the 3,5-disubstituted benzene-sulfonylurea derivative pyrazole analogs are predicted to have low inhibitory activity against the α-glucosidase enzyme. Further, all compounds showed good aldose reductase inhibitor activity and had lower binding free energy values ​​than tolrestat as the positive control (-6.82 kcal/mol). Compound 5C has the best potential inhibitory activity against the aldose reductase enzyme compared to the other test compounds, because it has the lowest binding free energy value (-8.76 kcal/mol) and interacts with important residues on the receptor forming four hydrogen bonds, namely the carbonyl group of SO2 with residues Trp111 and His110, and the carbonyl group of the amide with residues His110 and Tyr48, as well as 3 hydrophobic bonds, namely a pyrazole ring with residues Leu300, Trp219 and a furan ring with Phe122. ADMET properties of the compounds are also predicted. This information provides an opportunity for a 5C compound as an aldose reductase inhibitor agent to develop drug candidates with better and safer activities.
Co-Authors Adel Zamri Adel Zamri Bambang Purwono Beta Achromi Nurohmah Beta Achromi Nurohmah Chairil Anwar Denai Wahyuni Denai Wahyuni Emmy Yuanita Emmy Yuanita Eti Norhaslinda Fitra Perdana Hamiro, Fauzia Hasmalina Nasution Hendra, Rudi Ika Septiana Jasril Jasril Kamal Rullah Lazulva Lazulva, Lazulva Lisa Utami Maria Ulfa Mifthahul Jannah Nasution, Annio Indah Lestari nasution, Nurlaili Netti Gustina Nur Enizan Nurlaili Nurlaili Nurlaili Nurlaili Nurlailli Nasution Nurul Hidayah Olif Syahbella Perdana , Fitra Prasetya Prasetya Prasetya Prasetya, Prasetya Putri, Rahmayani Indah Rahayu, Anggi Putri Rahmadini Syafri Rahmiwati Hilma Ramadhanti, Aulia Rizki Retno Hidayati Rudi Hendra Saprizal Hadisaputra Sari, Meidita Kemala Sari, Nila Puspita Siregar, Sri Hilma Siregar, srihilma Sri Hilma Siregar Sudirman Sudirman Suma Rahmani Harahap Tri Dharmayani, Ni Komang Trisiwi Kusuma Ningrum Wirdati Irma Wulan Sari, Wulan Yeni Yernita Yuana Nurulita Yuana Nurulita Yuharmen Yuharmen Yuharmen, Yuharmen Yum Eryanti Yum Eryanti Yuni Fatisa `Nasution, Hasmalina