Rehatta, Nancy Margarita
Departemen Anestesiologi Dan Reanimasi, RSUD Dr. Soetomo – Fakultas Kedokteran Universitas Airlangga Surabaya

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Journal : Jurnal Veteriner

The Difference of Results in Abdomen and Anus Area Measurement With Non-Contact Infrared Thermometer Anna Surgean Veterini; Nancy Margarita Rehatta; Hamzah Hamzah; Widijiati Widijiati; Sarmanu Sarmanu; Subijanto Marto Soedarmo; Widodo Jatim Pudjirahardjo; Annis Catur Adi; Heni Rachmawati; I Ketut Sudiana
Jurnal Veteriner Vol 22 No 2 (2021)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (127.022 KB) | DOI: 10.19087/jveteriner.2021.22.2.183

Abstract

Study about sepsis is chalenging to get the right therapeutic method. One clinical signs of the sepsis mice model is changes in body temperature. An easy way to examine body temperature is using infrared non-contact thermometer. The aim of this study is to compare the body temperature obtained from infrared non-contact thermometer at the abdomen and anus area. We used male Mus musculus mice, body weight of 25–30 grams, were divided into 2 groups (control and treated groups). In the control group, mice were injected with NaCl 0.9% solution, with the amount of NaCl volume equal to LPS. In the treated group, mice were injected with 2.5 mg/kgBW of LPS intraperitoneally. Body temperature measurement was measured in abdomen (tabd) and anus (tan) area. Body temperature was measured at 8th and 24th hour after LPS or NaCl injection. Body temperature value result using tabd was higher than tan. LPS injection to mice produced an increase in body temperature but was not significant when compared to the control group (8th and 24th hour). The mean difference between tabd and tan in 8th hour control groups respectively were 2.12oC. The mean difference between tabd and tan in 24th hour control groups 4.6oC. The mean difference in treated groups (8th hour) was 4.66oC, while it was 4.77oC in the 24th hour treated groups. LPS could caused vasodilation of the vessels, the measurement area of non contact-infrared thermometer will be the most important factor to be considered; tan may closer to the physiology condition.
Description of Gastric Acidity (pH) with Simple Method in Lipopolysaccharide Induced Mice Anna Surgean Veterini; Bambang Wahjuprajitno; Nancy Margarita Rehatta; Heni Rachmawati; Subijanto Marto Soedarmo; I Ketut Sudiana; Widodo Jatim P; Annis Catur Adi; Rachmad Suhanda; Sarmanu Sarmanu; Widjiati Widjiati
Jurnal Veteriner Vol 24 No 1 (2023)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19087/jveteriner.2023.24.1.55

Abstract

The gastrointestinal acidity/pH can considerably influence the stability and absorption of oral medications. As a result, understanding the circumstances for drug delivery requires knowledge of gastrointestinal pH. Mice injected with lipopolysaccharide (LPS) are used in the most well-studied animal models of sepsis. However, information on gastrointestinal pH in sepsis mice is still insufficient. This study was conducted to identify gastric pH values in mice induced by lipopolysaccharide. The LPS was injected intraperitoneally as well as 0.9% NaCl as control groups. Treated groups (LPS) consisted of four groups and the control group (0.9% NaCl) consisted of four groups. Ten mice were used in each group. Gastric pH measurement was conducted using pH meter Lutron PH-201. Based on this study, the factors that influenced gastric pH in sepsis animal models were the LPS doses and the time after LPS injection. The results of gastric pH measurement in sepsis mice did not show a decrease in the pH compared to the normal conditions. The dose of LPS significantly influences the gastric pH change.
Co-Authors , Nabilah A. Himendra Wargahadibrata Abdul Kadir Munsy Agustina Salinding Ahmad, Bahtiar Amelia, Elena Ghentilis Fitri Anna Surgean Veterini Annis Catur Adi Atika atika Atiya Nurrahmah Aulia Rahmi Bambang Wahjuprajitno Benny Iswanto Pantoro Bunga Priscilla Rotua Manurung Candra Dwantara Ramadhan Cecilia Felicia Chandra Choesnan Effendi Dina Arini Izzah Eddy Rahardjo Elena Ghentilis Fitri Amelia Elizeus Hanindito Erwin Astha Triyono Feriawan Tan Fitri Amelia, Elena Ghentilis Fundhy Sinar Ikrar Prihatanto, Fundhy Sinar Ikrar Hamzah Hamzah Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo****** Harijono, Bambang HENI RACHMAWATI HERAWATI, LILIK Izzah, Dina Arini Karimah, Azimatul Khoir Amaliin Lila Tri Harjana Lucky Andriyanto Maulydia, Maulydia Mohammad Sofyan Harahap Muhammad Hamdan Muhammad Hamdan Nabilah Nenden Suliadiana Fajarini Prananda Surya Airlangga Prattama Santoso Utomo Rachmad Suhanda Rizkiya, Putri Rochmanti, Maftuchah Rochmanti Rudi Iskandar Suryadani S.Pd. M Kes I Ketut Sudiana . Sarmanu, Sarmanu Semedi, Bambang Pujo Sinaga, Nur Flora Nita TB Siti Khaerunnisa Subijanto Marto Soedarmo Subijanto Marto Soedarmo Suksmi Yitnamurti Sulistiawan, Soni Sunarso Sulistiawan, Soni Sunarso Tan, Feriawan Tatang Bisri Tedyanto, Eric Hartono Teguh Sylvaranto Turchan, Agus Utariani, Arie Widijiati Widijiati Widjiati Widjiati Widodo Jatim P Widodo Jatim Pudjirahardjo Windhu Purnomo Yitnamurti, Suksmi Yoga Pamungkas Susani Yuani Setiawati