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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Pharmascience Medical Laboratory Technology Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Kreativitas PKM Jurnal Mandala Pharmacon Indonesia Jurnal Kajian Ilmiah Kesehatan Dan Teknologi (JKIKT) Borneo Journal Of Pharmascientech Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan International Journal of Health and Pharmaceutical (IJHP) Jurnal Bakti Untuk Negeri FISIO MU: Physiotherapy Evidences Jurnal Pengabdian Ikifa
Nazhipah Isnani
Politeknik Unggulan Kalimantan
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health

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KARAKTERISTIK ANAK PENDERITA PNEUMONIA YANG MENDAPATKAN ANTIBIOTIK DI INSTALASI RAWAT INAP RSUD ULIN BANJARMASIN TAHUN 2022 Jamil, Muhammad Muhtadin; Isnani, Nazhipah; Muliyani, Muliyani; Zaini, Muhammad
Jurnal Kajian Ilmiah Kesehatan dan Teknologi Vol 5 No 2 (2023)
Publisher : Politeknik Unggulan Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52674/jkikt.v5i2.116

Abstract

Pneumonia merupakan penyakit yang menjadi masalah diberbagai negara berkembang termasuk Indonesia. Pneumonia yang terjadi di Indonesia cenderung meningkat untuk periode prevalence pneumonia semua umur dari 2,1% tahun 2007 menjadi 2,7% tahun 2013, pneumonia yang tinggi terjadi pada kelompok umur 1-4 tahun, kemudian mulai meningkat pada umur 45-54 tahun. Penelitian ini adalah penelitian deskriptif dengan metode pengambilan data secara retrospektif dengan teknik sampling yaitu total sampling. Retrospektif dilakukan berdasarkan data yang sudah lalu, merujuk pada data sekunder berupa rekam medis pasien selama dirawat di RSUD Ulin Banjarmasin sampel berjumlah sebanyak 110 data rekam medis pasien pneumonia anak di instalasi rawat inap RSUD Ulin Banjarmasin periode Januari-Desember tahun 2022. Berdasarkan jenis kelamin diperoleh sebanyak 98 pasien dengan laki-laki berjumlah 57(58,16%) dan perempuan berjumlah 41(41,84%). Pneumonia anak banyak terjadi pada usia rentang 0-2 tahun yaitu sebanyak 72 (83,67%) dan pada usia 2-12 tahun sebanyak 26 (26,53%)..
GAMBARAN POTENSI INTERAKSI OBAT KORTIKOSTEROID PADA PASIEN PNEUMONIA ANAK DI INSTALASI RAWAT INAP RSUD ULIN BANJARMASIN Widodo, Ridho Dwi; muliyani, muliyani; Isnani, Nazhipah; Zaini, Muhammad
Jurnal Kajian Ilmiah Kesehatan dan Teknologi Vol 5 No 2 (2023)
Publisher : Politeknik Unggulan Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52674/jkikt.v5i2.117

Abstract

Pneumonia is mostly caused by bacterial, fungal, viral or parasitic microorganisms which cause the alveoli in the lungs to become inflamed and filled with fluid or mucus. Pneumonia occurs when parasites (pathogens) subvert or enhance the immune system, thereby causing inflammation or inflammation. in the lungs, the research method used in this study is a retrospective descriptive approach, namely an observational approach. This research was conducted at the Ulin Banjarmasin Regional Hospital, the population and samples using corticosteroids were 30 samples in 2020 - 2021 in pediatric pneumonia patients at the installation inpatient treatment at Ulin District Hospital, Banjarmasin. The variable used is a single variable, namely corticosteroid drug interactions in pediatric pneumonia patients at the Ulin Hospital Banjarmasin inpatient installation. (37%), with an age range of 0 - 5 years as many as 20 people (67%) and ages 6 - 12 years as many as 10 people (33%), the corticosteroid drug used was dexamethasone for 29 people (96.7%) and Methylprednisolone 1 prescriptions (3.3%), the incidence of drug interactions was 9 prescriptions (30%) and those that did not occur were 21 prescriptions (70%), with major levels being 0, moderate 0 and minor being 9 prescriptions (30%).
Studi Deskriptif Faktor Produk, Harga, Tempat dan Promosi pada Produk Bedak Dingin Bunga Tanjung Zaini, Muhammad; Muliyani, Muliyani; Isnani, Nazhipah; Wulandari, Ihya
Jurnal Kajian Ilmiah Kesehatan dan Teknologi Vol 6 No 1 (2024)
Publisher : Politeknik Unggulan Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52674/jkikt.v6i1.127

Abstract

The use of bedak dingin has been passed down from generation to generation by the people of South Kalimantan. Bedak dingin made from rice as the main ingredient is believed to make the skin smooth, brighten the skin, prevent and eliminate acne. This research aims to provide an overview of the application of the marketing mix concept which includes product, price, place and promotion for bedak dingin Bunga Tanjung in South Kalimantan. The research was carried out using a descriptive method where the samples used were women aged 17 – 45 years who live in South Kalimantan and have used bedak dingin Bunga Tanjung more than once. The instrument used was a questionnaire with five Likert scales. The sample collection technique is Accidental Sampling. Based on the Cochran formula, the sample size was 100 respondents. Data analysis was carried out with the help of Microsoft Excel in the form of percentage data presented in table form. The research results show that the product variable is dominated by the product indicator offered (75%), the price variable is the affordable price indicator (87%), the place variable is an easily accessible location (60%) and product promotions placed in the window (56%).
Qualitative Analysis of COVID-19 Vaccine Reactogenicity in Banjarmasin City, South Kalimantan During the Pandemic Muliyani, Muliyani; Isnani, Nazhipah; Annisa, Rahmi; Ramadhani, Juwita
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025 ( Indonesia - Thailand)
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.457

Abstract

The World Health Organization (WHO) officially recognized COVID-19 as a pandemic. By March 29, 2020, global cases had reached 634,835 with 33,106 fatalities. In Indonesia, there were 1,528 confirmed infections and 136 deaths. According to Indonesia's Presidential Regulation No. 99 of 2020, the government is expediting the acquisition of COVID-19 vaccines and the vaccination program to combat the pandemic. COVID-19 has spread extensively across nearly all provinces in Indonesia. The government remains committed to gradually delivering safe, high-quality, and effective vaccines. Despite these efforts, many people remain hesitant about vaccination due to concerns over side effects and vaccine safety. This study aims to qualitatively analyze the reactogenicity of COVID-19 vaccines. Using a descriptive observational qualitative design, informants were selected through purposive sampling. Reported side effects include drowsiness, injection site pain, increased appetite, fever around 38-39°C, weakness, recurrence of asthma, chest tightness, cough, and runny nose. The most common reactions observed were fever up to 39°C (18.51%) and vomiting (11.11%).
Pemberdayaan Kader dan Lansia dalam Pengelolaan Serta Pemanfaatan Toga sebagai Upaya Dalam Mengatasi Hipertensi di Desa Sungai Batang Kabupaten Banjar Isnani, Nazhipah; Triyasmono, Liling; Rizki, Muhammad Ikhwan; Rahmatullah, Satrio Wibowo; Sandi, Dita Ayulia Dwi; Izma, Hayatun; Redanti, Hema Novita; Humaidy, Mizan; Amali, Dzikra Aulia
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 8, No 12 (2025): Volume 8 No 12 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v8i12.22551

Abstract

ABSTRAK Hipertensi merupakan salah satu penyakit tidak menular dengan prevalensi tinggi dan menjadi faktor risiko utama penyakit kardiovaskular. Salah satu upaya pencegahan yang dilakukan melalui pemberdayaan masyarakat dengan edukasi dan pemanfaatan Tanaman Obat Keluarga (TOGA). Kegiatan ini bertujuan untuk meningkatkan pengetahuan dan keterampilan kader serta lansia dalam pencegahan hipertensi di Desa Sungai Batang. Kegiatan ini dilakukan dengan metode ceramah interakif, diskusi, pemerian edukasi dan pelatihan pengolahan TOGA. Evaluasi pengetahuan peserta dilakukan menggunakan pre-test dan post-test, kemudian dianalisis secara deskriptif kuantitatif. Hasil dari kegiatan ini didapatkan peningkatan rata-rata pengetahuan peserta dari 87,14% pada pre-test menjadi 100% pada post-test, dengan nilai p=0,0001 yang menunjukkan perbedaan siginifikan. Selain itu, peserta juga memperoleh keterampilan dalam meracik ramuan herbal antihipertensi dari TOGA. Edukasi hipertensi dan pelatihan TOGA efektif meningkatkan pengetahuan dan keterampilan kader serta lansia dalam mendukung upaya promotif dan preventif pada penyakit hipertensi di Desa Sungai Batang. Kata Kunci: Hipertensi, Edukasi Kesehatan, Tanaman Obat Keluarga, Pemberdayaan Masyarakat.  ABSTRACT Hypertension is a non-communicable disease with a high prevalence and a significant risk factor for cardiovascular disease. One preventative measure is community empowerment through education and the use of Family Medicinal Plants (TOGA). This activity aims to improve the knowledge and skills of community health workers and the elderly in preventing hypertension in Sungai Batang Village. The activity used interactive lectures, discussions, educational presentations, and TOGA processing training. Participants' knowledge was evaluated using pre- and post-tests, then analysed descriptively using quantitative data. This activity showed an increase in average participant knowledge from 87.14% in the pre-test to 100% in the post-test, with a p-value of 0.0001 indicating a significant difference. Furthermore, participants also gained skills in preparing antihypertensive herbal concoctions from TOGA. Hypertension education and TOGA training effectively improved the knowledge and skills of community health workers and the elderly in supporting promotive and preventive efforts for hypertension in Sungai Batang Village. Keywords: Hypertension, Health Education, Family Medicinal Plants, Community Empowerment
Molecular Docking Analysis Of Phenolic and Flavonoid Compounds from Eichhornia Crassipes for Antidiabetic Activity Through Interaction with PPAR- γ (5Y2O) and A-Glucosidase (3TOP) Muslimawati, Khoirunnisa; Fakih, Taufik Muhammad; Akbar, Nabila Hadiah; Putra, Aditya Maulana Perdana; Isnani, Nazhipah
Journal of Pharmascience Vol 12, No 2 (2025): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i2.23583

Abstract

Diabetes Mellitus Tipe 2 (DMT2), ditandai dengan resistensi insulin dan hiperglikemia. Penelitian ini mengevaluasi potensi 30 senyawa golongan fenolik dan flavonoid dari Eichhornia crassipes sebagai agen antidiabetes melalui studi in silico, meliputi uji toksisitas (ToxTree 3.1.0, ProTox 3), analisis ADME (SwissADME), dan molecular docking (AutoDock 4.2.6). Struktur ligan uji diperoleh dari PubChem, sedangkan reseptor PPAR-γ (PDB ID: 5Y2O) dan α-Glukosidase (PDB ID: 3TOP) diunduh dari RCSB Protein Data Bank. Sebelum docking, analisis toksisitas dan ADME dilakukan. Hasil docking menunjukkan Tricin (flavonoid) berinteraksi baik dengan kedua reseptor dan memiliki nilai energi Gibbs -7.53 kcal/mol untuk PPAR-γ dan -5.19 kcal/mol untuk α-Glukosidase, mendekati ligan asli Pioglitazone (-10.03 kcal/mol) dan Acarbose (-6.86 kcal/mol). Interaksi ligan-reseptor Tricin melibatkan ikatan hidrogen dan kontak hidrofobik dengan residu kunci (misalnya, ARG288 dan TYR pada PPAR- γ, residu GLN1561 dan GLN1372 pada α-Glukosidase), mencerminkan interaksi ligan asli. Prediksi toksisitas mengklasifikasikan Tricin sebagai senyawa dengan risiko toksisitas rendah (Cramer Rules Kelas I, Kroes TTC). Selanjutnya, evaluasi ADME menunjukkan bahwa Tricin memenuhi Lipinski's Rule of Five, yang mengindikasikan penyerapan dan bioavailabilitas oral yang baik. Secara keseluruhan, senyawa Tricin dari E. crassipes menunjukkan potensi signifikan sebagai kandidat agen antidiabetes melalui penghambatan PPAR-γ dan α-Glukosidase yang selanjutnya memerlukan validasi dnegan pengujian in vitro dan in vivo. Kata Kunci: Eichhornia crassipes, Molecular Docking, Antidiabetic, PPAR-γ, α-Glucosidase Type 2 Diabetes Mellitus (T2DM), is characterized by insulin resistance and persistent hyperglycemia. This study investigated the antidiabetic potential of 30 phenolic and flavonoid compounds derived from Eichhornia crassipes using in silico approaches, including toxicity assessments (ToxTree 3.1.0, ProTox 3), ADME analysis (SwissADME), and molecular docking (AutoDock 4.2.6). Ligand structures were retrieved from PubChem, while PPAR-γ (5Y2O) and α-Glucosidase (3TOP) receptors were obtained from the RCSB Protein Data Bank. Toxicity and ADME analyses were conducted prior to molecular docking, which employed the Genetic Algorithm with 50 conformations. Docking results revealed that Tricin (a flavonoid) exhibited strong interactions with both receptors, with Gibbs free energy values of -7.53 kcal/mol for PPAR-γ and -5.19 kcal/mol for α-Glucosidase. These values are comparable to those of the native ligands Pioglitazone (-10.03 kcal/mol) and Acarbose (-6.86 kcal/mol). Tricin formed hydrogen bonds and hydrophobic contacts with key active site residues including, ARG288 and TYR327 in PPAR-γ, GLN1561 and GLN1372 in α-Glucosidase), mirroring the interactions of the native ligands. Toxicity predictions classified Tricin as low risk (Class I Cramer Rules, Kroes TTC). Furthermore, ADME evaluation showed that Tricin (aglycone) is fully compliant with Lipinski's Rule of Five, suggesting favorable properties for oral absorption and bioavailability. In conclusion, Tricin from E. crassipes demonstrates significant potential as an antidiabetic candidate and warrants further in vitro and in vivo validation.
KARAKTERISTIK PASIEN DIABETES MELLITUS TIPE 2 YANG MENDAPATKAN TERAPI ANTIDIABETIK ORAL DI RSUD DR. H. MOCH.ANSARI SALEH BANJARMASIN muliyani, muliyani muliyani; isnani, nazhipah
Jurnal Kajian Ilmiah Kesehatan dan Teknologi Vol 1 No 1 (2019)
Publisher : Politeknik Unggulan Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (334.53 KB) | DOI: 10.52674/jkikt.v1i1.3

Abstract

Diabetes melitus (DM) merupakan kumpulan gejala metabolik yang timbul pada diri seseorang yang disebabkan oleh adanya peningkatan glukosa darah akibat rusaknya sekresi insulin atau resistensi terhadap insulin atau keduanya. Di Indonesia, jumlah penyandang DM semakin tahun juga semakin menunjukkan peningkatan yang sangat tinggi. Pada tahun 2000, jumlah penderita DM di Indonesia sebanyak 8,4 juta jiwa dan diperkirakan akan mencapai angka 21,3 juta jiwa pada tahun 2030 nanti. Penelitian ini bertujuan untuk mengetahui karakteristik pasien, tingkat kepatuhan pasien. Metode penelitian merupakan penelitian Observasional Crossectional dengan mengambil data pasien secara prospektif dengan melakukan penelusuran dokumen terdahulu, yaitu pada lembar rekam medik pasien rawat inap periode Juni – Juli 2017. Hasil penelitian ini menunjukkan bahwa Berdasarkan karakteristik subjek penelitian sebanyak 28 responden. Usia < 55 tahun sebanyak 12 orang (42,9%) dan >55 tahun sebanyak 16 orang (57,1%), tingkat pendidikan yang paling sedikit adalah > SMA sebanyak 11 orang (39,3%) dan <SMA sebanyak 17 orang (60,7%), 16 orang berjenis kelamin perempuan (57,1%) dan sebanyak 12 orang (42,9%), 23 orang yang bekerja (82,1%), dan yang tidak bekerja sebanyak 5 orang (17,9%), lama pasien menderita DM tipe 2 sebagian besar > 5 tahun sebanyak 18 responden (64,3%) dan paling sedikit < 5 tahun sebanyak 10 (35,7%), jenis pengobatan Monoterapi sebanyak 16 responden (57,43%) dan Kombinasi sebanyak 12 (42,57%).
Penanganan Obat Look Alike Sound Alike (LASA) dalam Praktik Kefarmasian: Tinjauan Literatur Naratif Zaini, Muhammad; Isnani, Nazhipah; Hikmah, Siti Nur; Muliyani, Muliyani
Jurnal Kajian Ilmiah Kesehatan dan Teknologi Vol 7 No 2 (2025)
Publisher : Politeknik Unggulan Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52674/jkikt.v7i2.304

Abstract

Medication errors remain a sndaignificant challenge in efforts to improve patient safety, one of which is triggered by the use of Look Alike Sound Alike (LASA) medications. LASA drugs share similarities in naming, pronunciation, or packaging appearance, thereby increasing the risk of errors during prescribing, preparation, and administration stages. This article aims to review the literature addressing the concept, impact, and management strategies of LASA medications in pharmacy practice from a pharmaceutical management perspective. The research method employed was a narrative literature review of scientific articles published within the last five years and sourced from the Scopus and PubMed databases. The findings indicate that optimal management of LASA medications requires a systematic approach through risk management policies, implementation of standard operating procedures, utilization of health information technology, and strengthening the role of pharmacists within the healthcare system. However, empirical studies examining the effectiveness of LASA policy implementation in healthcare facilities in Indonesia remain limited. Therefore, the development of contextual and sustainable LASA management models is needed to support the enhancement of patient safety.
PENYULUHAN PENGGUNAAN ANTIBIOTIK KEPADA MASYARAKAT DESA MANTUIL (PULAU BROMO) KOTA BANJARMASIN Iqlima Iqlima; Muliyani Muliyani; Nazhipah Isnani; Muhammad Zaini
Jurnal Pengabdian IKIFA Vol. 1 No. 1 (2021): Jurnal Pengabdian IKIFA
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antibiotics are drugs used to kill bacteria so they are used to treat infections. Treatment with antibiotics must be on a doctor's prescription. The misuse of antibiotics can pose a dangerous risk of resistance. WHO has stated that deaths caused by antibiotic resistance reached 700,000 people in 2013. Education on the proper use of antibiotics aims to increase public awareness and understanding of how to use antibiotics correctly and appropriately. The implementation of this service in the form of counseling was carried out in Mantuil Village (Bromo Island) Banjarmasin City. The method used is through oral presentations delivered by pharmacists, questions and answers, and mini-quizzes. The results of this educational activity on the use of antibiotics have a positive influence on the entire community as evidenced by the community answering correctly on every given mini-quizes. The community is also active in asking questions about the use of antibiotics so that the community is considered enthusiastic in participating in the educational activity. It can be concluded that with this activity, the community becomes more aware of the proper and correct use of antibiotics.
PEMBINAAN SKILL PEMBUATAN MASKER WAJAH HERBAL KEPADA SISWA SMK UNGGULAN HUSADA MELALUI PERAN DOSEN SEBAGAI GURU TAMU Muliyani Muliyani; Nazhipah Isnani; Muhammad Zaini; Iqlima Iqlima; Popong Nur Apipah
Jurnal Pengabdian IKIFA Vol. 1 No. 1 (2021): Jurnal Pengabdian IKIFA
Publisher : Sekolah Tinggi Ilmu Kesehatan IKIFA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Vocational education directs students to work in the industry with the skills they have in accordance with the abilities they take in the vocational education. Many problems have happened to students lately and another problem is the lack of adequate practice facilities. Various efforts and efforts must be made by schools to overcome this problem, among others, by fulfilling the necessary facilities through self-help and requests for assistance for facilities and teacher training to the central and regional governments. In the problems above, there are problems that occur in education, especially in SMK Unggulan Husada Banjarmasin, namely the management in the field of entrepreneurship which still needs refreshment to be able to implement the business that will be run from the skills possessed by students, especially the pharmacy department. So, there is a need for the dedication of lecturers who act as guest teachers. The learning method is known as a guest teacher or an outsider who is not a teacher giving lessons to students in order to overcome the backwardness of technology and learning facilities. The Resources Person (Guest Teacher) learning method is based on resource-based learning. Learning outcomes have increased after being given motivations and very enthusiastic during practical tutoring.
Co-Authors Agustina, Ni Kadek Ayu Akbar, Nabila Hadiah Amali, Dzikra Aulia Andalusia, Rizka Anna Khumaira Sari Aulia, Hilya Auralia, Najma Ayuchecaria, Noverda Buih, Putri Helena Junjung Devia Pratiwi Dewi Wulandari Dewi Wulandari Dyah Aryani Perwitasari Enny Fauziah Fitria, Raudatul Haridini Intan Mahdi Haridini Intan Mahdi Haridini Intan Mahdi Hikmah, Siti Nur Humaidy, Mizan Iqlima Iqlima Ira Maya Sari Izma, Hayatun Jamil, Muhammad Muhtadin Jhudi Bonosari Soediono Juwita Ramadhani Khairunnisa Khoirunnisa Muslimawati Kumala, Dinna Fitria Liling Triyasmono Mahdi, Haridini Intan Malahayati, Siti Maulida Rahmah Maulida, Khelda Mochammad Maulidie Alfiannor Saputera Muhammad Arif Riyadi Muhammad Ikhwan Rizki Muhammad Muhatadin Jamil Muhammad Zaini Muhammad Zaini Muhammad Zaini Muliyani muliyani muliyani Muliyani Muliyani muliyani, muliyani muliyani muliyani, muliyani muliyani Nabila Hadiah Akbar Nafi&#039;ah Nafi&#039;ah Nafi’ah, Nafi’ah Nur Aulya Aulya Popong Nur Apipah Putra, Aditya Maulana Perdana Putri Sheila Wardhani Rahmatullah, Satrio Wibowo Rahmi Annisa Ramadhani , Syahrizal Ravenalla Abdurrahman Al Hakim Sampurna Putra S Redanti, Hema Novita Rini Audina Rizka Andalusia Rizka Andalusia Rizka Andalusia Saksono, Reni Yustiati Samsul Hadi Sandi, Dita Aulia Dwi Sandi, Dita Ayulia Dwi Sari , Anna Khumaira Setiawan, Feri Taufik Muhammad Fakih Widodo, Ridho Dwi Wirawan Adikusuma Wulandari, Ihya