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Validasi Metode Analisis Beberapa Senyawa Metabolit Sekunder pada Andrographis paniculata, Zingiber officinale var. rubrum, dan Nigella sativa sebagai Terapi COVID-19: Sebuah Review Farendina Suarantika; Nabila Hadiah Akbar
Jurnal Ilmiah Medicamento Vol 8 No 1 (2022): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v8i1.3355

Abstract

Several Indonesian plants contain active compounds that can limit infection and replication of SAR-CoV-2 based on their activity against relevant therapeutic targets. This literature review aims to review validated analytical methods on bitter plants (Andrographis paniculata), red ginger (Zingiber officinale var. rubrum), and black cumin (Nigella sativa), which has potential therapeutic activity against SARS-CoV-2. Sources of information used in this literature review were obtained using search engines such as Science Direct, Google Scholar, and PubMed. Andrographolide (sambiloto), gingerol (red ginger), and thymoquinone (black cumin) were shown to be specifically capable of inactivating SARS-CoV-2 with good targeting accuracy. The generally validated plant analysis methods used RP-HPLC/HPTLC, UV-Vis Spectrophotometry, GC-FID, GC, and UHPLC-DAD.
ANALISIS MANAJEMEN PENYIMPANAN OBAT DI PUSKESMAS SE-KOTA BANJARBARU Nabilah Hadiah Akbar; Nani Kartinah; Candra Wijaya
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 6, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.354

Abstract

Manajemen obat merupakan suatu rangkaian kegiatan paling penting yang mendapatkan alokasi dana dari pemerintah sebesar 40-50% dari dana alokasi pembangunan kesehatan yang menyangkut aspek perencanaan, pengadaan, penyimpanan dan pendistribusian obat. Proses penyimpanan merupakan proses yang sangat penting pada kegiatan manajemen obat. Penyimpanan merupakan suatu kegiatan pengamanan terhadap obat-obatan yang diterima agar aman (tidak hilang), terhindar dari kerusakan fisik maupun kimia dan mutunya tetap terjamin. Penelitian ini bertujuan untuk menganalisis proses manajemen penyimpanan obat di seluruh puskesmas di kota Banjarbaru melalui analisis manajemen penyimpanan obat ditinjau dari indikator stok mati, obat kadaluwarsa dan stok akhir obat di puskesmas se-kota Banjarbaru. Desain penelitian yang digunakan adalah cross sectional dengan analisis data menggunakan Analyze frequencies.Instrumen penelitian yang digunakan adalah LPLPO dan catatan obat kadaluwarsa tahun 2014-2015 puskesmas se-kota Banjarbaru sebagai sumber data. Hasil persentase stok mati tahun 2014- 2015 sebanyak 41,07%; 38,54%, hasil persentase obat kadaluwarsa tahun 2014- 2015 sebanyak 0,50%; 0,52%, dan hasil persentase nilai stok akhir obzt tahun 2014- 2015 sebanyak 14,27%; dan 16,94%. Hal ini menunjukkan bahwa proses manajemen obat berdasarkan banyaknya persentase stok mati, obat kadaluwarsa dan nilai stok akhir obat di seluruh puskesmas di kota Banjarbaru masih belum efisien.
Ethnobotanical Study of Medicinal Plants of Banjar and Java Tribes in Pandansari Village, South Kalimantan Sutomo Sutomo; Alif Vera Aprilianes; Nani Kartinah; Arnida Arnida; Khoirunnisa Muslimawati; Nabila Hadiah Akbar
Borneo Journal of Pharmacy Vol. 7 No. 2 (2024): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v7i2.6636

Abstract

In Pandansari village, South Kalimantan, Indonesia, residents from Banjar and Javanese communities traditionally utilize medicinal plants as alternatives to conventional medicine. This study aimed to explore the demographics, plant use practices, and preliminary phytochemical analysis of these plants. Using a qualitative, phenomenological approach, semi-structured interviews and questionnaires were conducted with four purposively selected informants. The findings revealed 52 medicinal plant species. Leaves were the most commonly used plant part (40%), followed by boiling as the preferred processing method (54%) and drinking as the primary route of administration (58%). Two unidentified plants, asam sembelekan and daun malaysia, were frequently mentioned. Phytochemical screening detected flavonoids, saponins, phenols, and terpenoids in asam sembelekan, while daun malaysia contained alkaloids, flavonoids, saponins, and terpenoids. These findings provide a foundation for further research on the efficacy and safety of these traditional medicinal plants in this community.
CHARACTERIZATION OF MUNDAR PERICARP (Garcinia forbesii) EXTRACT FROM BANJAR DISTRICT OF INDONESIA Rizki, Muhammad Ikhwan; Triyasmono, Liling; Alfandani, Gina; Hadiah Akbar, Nabila; Khumaira Sari, Anna
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1589

Abstract

The mundar plant (Garcinia forbesii) is a typical fruit of South Kalimantan. The people use mundar empirically as a spice, cosmetic, and medicine. The purpose of this study was to determine the characteristics of mundar extract from Karang Intan and Beruntung Baru districts in Banjar Regency. The collection of plants from two places, plant determination, and extraction with 70% ethanol. The extract was then characterized. The characterization showed that the Garcinia forbesii pericarp extract from both places was dark brown, distinctive odor, sour taste, and thick. Both extracts contained flavonoids, phenolics, tannins, saponins, glycosides, and anthraquinones. The chromatography of both extracts was the same and detected to alpha-mangosten. The extract from Karang Intan district has a yield 59.99%, total phenolic content 0.888%, moisture content 9.78%, total ash content 1.10%, and acid insoluble ash content 0.06%. The extract from Beruntung Baru district has a yield 58.74%, total phenolic content 0.823%, moisture content 9.93%, total ash content 1.59%, and acid insoluble ash content 0.04%. Garcinia forbesii pericarp extracts from from two places have the same organoleptical characteristics, phytochemical compounds, and chromatography patterns. The differences are in yield percentage, total phenolic content, water content, ash content, and acid insoluble ash content.
VALIDASI METODE ANALISIS SENYAWA METABOLIT SEKUNDER PADA MORINGA OLEIFERA LAM., DAN EUCALYPTUS GLOBULUS LABILL. Suarantika, Farendina; Akbar, Nabila Hadiah; Patricia, Vinda Maharani
Jurnal Inkofar Vol 8, No 1 (2024)
Publisher : Politeknik META Industri Cikarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46846/jurnalinkofar.v8i1.330

Abstract

Beberapa tanaman Indonesia seperti Moringa oleifera Lam. dan Eucalyptus globulus Labill. mengandung senyawa aktif yang dapat memberikan aktifitas farmakologis seperti antibakteri, antioksidan, antidiabetes, anti-kanker dan juga anti-inflamasi. Penelitian ini merupakan studi pustaka yang meninjau validasi metode dalam analisis senyawa aktif yang terdapat pada tanaman Moringa oleifera Lam. dan Eucalyptus globulus Labill. Adapun parameter yang terdapat pada dalam suatu validasi metode yaitu akurasi, linearitas, presisi, batas nilai deteksi, dan batas nilai akurasi. Sumber informasi yang digunakan pada kajian pustaka ini diperoleh dengan menggunakan search engine seperti Science direct, Google Scholar, dan PubMed. Kriteria inklusi mencakup artikel penelitian, tema artikel mengenai analisis metabolit sekunder Moringa oleifera Lam. dan Eucalyptus globulus Labill. Untuk kriteria eksklusi adalah artikel metode analisis metabolit sekunder selain Moringa oleifera Lam. dan Eucalyptus globulus Labill., tidak memuat data validasi, serta tidak memuat prosedur lengkap analisis. Berhasil dikumpulkan dan dianalisis sebanyak 45 artikel dan hasilnya validasi metode secara umum menggunakan instrumen RP-HPLC/HPTLC, Spektrofotometri UV-Vis, GC-FID, GC, dan UHPLCDAD. Kata Kunci: Validasi metode, Moringa oleifera Lam., Eucalyptus globulus Labill., Metabolit sekunder
Pengenalan Simplisia dan Pelatihan Pembuatan Teh Celup Telang dan Bawang Dayak Bagi Kader Puskesmas Mataraman Sari, Okta; Setiawan, Deni; Putra, Aditya Maulana Perdana; Wathan, Nashrul; Mardiati, Nurul; Lingga, Herningtyas Nautika; Akbar, Nabila Hadiah
Jurnal Pengabdian Kepada Masyarakat (MEDITEG) Vol. 9 No. 2 (2024): Jurnal Pengabdian Kepada Masyarakat (MEDITEG)
Publisher : Pusat Penelitian dan Pengabdian Kepada Masyarakat (P3M) Politeknik Negeri Tanah Laut (Politala)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34128/mediteg.v9i2.270

Abstract

Using traditional medicinal plants to create health products like herbal medicines and tea bags is one way to improve health. Telang (Clitoria ternatea) and Dayak Onion (Eleutherine bulbosa) are two types of plants that have great potential in the world of health, but their use has not been optimal. The purpose of this service is to improve the knowledge of Mataraman Health Centre cadres in the processing of herbal medicines and the utilisation of TOGA. At the Mataraman Health Center, community service has been conducted. The implementation of activities aimed at providing education on the introduction of herbal medicines using leaflets. Training is being conducted to process dry herbal medicines, utilize medicinal plants, and create tea bags. Evaluation of activities is carried out through pretests and posttests. A total of 10 cadres from Mataraman Health Centre participated in this activity. After receiving the education, the average level of knowledge among the participants increased to 84%. The use of herbal plants as herbal medicines can inspire the community to develop and preserve the potential of traditional medicinal plants. We hope that this activity will serve as a foundational step, providing cadres with valuable insights to develop herbal medicines.
EFEKTIVITAS PENGGUNAAN ANTIBIOTIK PADA PASIEN PNEUMONIA ANAK DI INSTALASI RAWAT INAP DI RSUD ULIN BANJARMASIN TAHUN 2022 Nazhipah Isnani; Muliyani; Muhammad Zaini; Muhammad Muhatadin Jamil; Hadiah Akbar, Nabila
Jurnal Insan Farmasi Indonesia Vol 7 No 3 (2024): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/nxj6e492

Abstract

Pneumonia is a disease that is a problem in various developing countries, including Indonesia. Pneumonia that occurs in Indonesia tends to increase with age. This research is descriptive research with a retrospective data collection method using a sampling technique, namely total sampling. The retrospective was carried out based on previous data, referring to secondary data in the form of patient medical records while being treated at the Ulin Hospital, Banjarmasin, a sample of 98 medical records of pediatric pneumonia patients at the Ulin Banjarmasin Hospital inpatient installation for the period January-December 2022. Based on the research results obtained that patients suffering from pneumonia experienced fever for a maximum of 1-3 days totaling 87 people (89%). The highest number of antibiotics used was a single antibiotic in the cephalosporin group, namely 33 people (32%). Based on the effectiveness of antibiotics based on the duration of fever, the use of Ampicillin+gentamicin in 32 patients (31%) reduced fever more within a period of 1-3 days.
Edukasi Pemanfaatan Mandiri TOGA kepada Kader Puskesmas Mataraman Putra, Aditya Maulana Perdana; Wathan, Nashrul; Lingga, Herningtyas Nautika; Setiawan, Deni; Sari, Okta Muthia; Mardiati, Nurul; Akbar, Nabila Hadiah; Sari, Risa Purnama; Rizkiyah, Noor Annisa; Salsabila, Risma Zahra; Salwa, Helmina
Jurnal Pengabdian Masyarakat Panacea Vol 2, No 3 (2024): Jurnal Pengabdian Masyarakat Panacea
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpmp.v2i3.13245

Abstract

Pemanfaatan TOGA secara mandiri merupakan salah satu inisiatif untuk meningkatkan keterlibatan masyarakat dalam pengelolaan TOGA. Kader memiliki peran dalam mendukung masyarakat dalam pengelolaan kebun TOGA di masing-masing daerah. Tujuan dari pengabdian adalah peningkatan pengetahuan tentang pemanfaatan TOGA secara mandiri pada kader Puskesmas Mataraman setelah pemberian edukasi. Pada tanggal 6 Agustus 2024, tim pengabdian memilih ceramah sebagai metode yang diterapkan dalam edukasi. Kegiatan ditargetkan bagi kader desa wilayah kerja Puskesmas Mataraman. Evaluasi edukasi, proses keenam ini dilakukan dengan memberikan kuesioner pengetahuan TOGA sebelum edukasi materi dan sesudah edukasi materi. Sebanyak 10 orang berhadir dalam kegiatan. Berdasarkan hasil pengabdian diperoleh rerata pengetahuan peserta sebelum edukasi materi sebesar 78 % ± 16,61. Adapun pengetahuan peserta sesudah edukasi materi sebesar 92 % ± 13,27. Tim pengabdian telah menyerahkan TOGA sebanyak 14 jenis tanaman obat kepada Puskesmas Mataraman. Berdasarkan hasil , pada kader di wilayah kerja Puskesmas Mataraman terjadi peningkatan pengetahuan setelah diberikan edukasi tentang pemanfaatan TOGA mandiri.Kata Kunci: Apotek Hidup, Obat Herbal, Penggunaan Herbal, SosialisasiImplementing TOGA independently is a strategy to enhance community engagement in TOGA management. Cadres play a crucial role in assisting the community in the management of TOGA gardens in their respective areas. The objective of the service is to enhance the understanding and proficiency of the Mataraman Health Centre cadres in independently utilising TOGA, after the provision of education. On August 6, 2024, the educational team opted on lectures as the instructional approach. The activity was specifically aimed at village cadres who are part of the operating area of the Mataraman Health Centre. The evaluation of education involves administering a TOGA knowledge questionnaire. There were a total of 10 individuals who participated in the activity. The participants' average knowledge before the educational content was 78% ± 16.61 (standard deviation), as indicated by the service results. The participants' knowledge, after the educational material, reached a mean of 92% with a standard deviation of 13.27. The service team has delivered a total of 14 different varieties of medicinal plants. Ultimately, after delivering education on the independent use of TOGA, there was a discernible enhancement in the knowledge of the cadres within the working area of the Mataraman Health Centre.
Uji Aktivitas Antidiabetes Ekstrak Etanol 96% Daun Bungur (Lagerstroemia speciosa) Secara In Vivo Khalid, Ega Rezkyan; Putra, Aditya Maulana Perdana; Sandi, Dita Ayulia Dwi; Akbar, Nabila Hadiah; Muslimawati, Khoirunnisa; Sari, Okta Muthia
Jurnal Pharmascience Vol 12, No 1 (2025): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i1.21737

Abstract

Diabetes Melitus (DM) telah menjadi permasalahan global dan termasuk ke dalam penyakit yang paling umum di dunia. Pengobatan menggunakan herbal merupakan salah satu solusi untuk mengatasi diabetes dan tumbuhan bungur (Lagerstroemia speciosa) merupakan herbal yang dapat mengatasi hal tersebut. Penelitian ini bertujuan untuk mengidentifikasi adanya aktivitas antidiabetes dan menentukan dosis yang memiliki efek antidiabetes terbesar pada ekstrak etanol 96% L. speciosa secara in vivo menggunakan metode Tes Toleransi Glukosa Oral (TTGO). Mencit diambil darahnya pada menit ke-0 dan diberikan larutan uji sesuai kelompoknya, yaitu kontrol negatif (Na-CMC), kontrol positif (metformin), dan kelompok dosis terpilih (75 mg/kgBB, 100 mg/kgBB, dan 125 mg/kgBB). Setelah 30 menit, diberikan larutan dekstrosa dan diambil darah mencit untuk diuji menggunakan pada menit ke-10, 20, 30, 45, 60, 90, dan 120 setelah pemberian dekstrosa. Hasil menunjukkan penurunan glukosa darah pada menit ke-20-30 pada seluruh kelompok perlakuan ekstrak dan kontrol positif, dimana kelompok dosis 125 mg/kgBB ekstrak L. Speciosa (159 ± 35,46) menghasilkan penurunan kadar glukosa yang tidak jauh berbeda dengan penurunan yang terjadi pada kelompok metformin (150,4 ± 46,42). Hasil uji statistik menunjukkan bahwa kadar glukosa darah kelompok perlakuan pada menit ke-30 terdapat perbedaan bermakna dengan kontrol negatif (Sig. <0,05) dan tidak berbeda bermakna dengan kontrol positif (Sig. ≥0,05). Kesimpulan penelitian ini adalah Hasil uji Tes Toleransi Glukosa Oral (TTGO) menunjukkan adanya aktivitas antidiabetes oleh ekstrak etanol 96% daun L. speciosa yang ditandai dengan adanya penurunan kadar glukosa darah pada mencit, efek antidiabetes terbesar pada ekstrak etanol 96% daun L. speciosa dengan dosis 125 mg/kgBB.
PENYULUHAN POLA HIDUP BERSIH DAN SEHAT (PHBS) PADA ANAK PANTI ASUHAN RAHMAH AL ASRI BANJARMASIN Isnani, Nazhipah; Muliyani, Muliyani; Akbar, Nabila Hadiah; Zaini, Muhammad
Jurnal Bakti untuk Negeri Vol 5 No 1 (2025): Jurnal Bakti Untuk Negeri
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/v9yak311

Abstract

Clean and healthy living behavior is behavior that is implemented by each person with their own awareness and carried out continuously every day to achieve the level of health needed to live a healthy and active life. Children need to know about PHBS because children are the group most vulnerable to disease, especially school-aged children. The aim of this community service is so that orphanage children are exposed to and receive information about PHBS so they can apply it in their daily lives. The method of this service activity is carried out through lectures and discussions held at the orphanage. The participants who attended were 12 orphanage children along with the orphanage management. The results obtained from this activity were that participants had quite high interest. This can be seen from the enthusiasm of the children in paying attention to the explanation and asking and providing answers to the speaker's questions.