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Wahyu Setia Budi
Department Of Physics, Faculty Of Science And Mathematics, Diponegoro University
Arts Astronomy Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Other

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Journal : YOUNGSTER PHYSICS JOURNAL

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PENENTUAN WAKTU PARO BIOLOGI TC99M MDP PADA PEMERIKSAAN BONE SCANNING Titi Purwati; Wahyu Setiabudi
Youngster Physics Journal Vol 5, No 4 (2016): Youngster Physics Journal Oktober 2016
Publisher : Jurusan Fisika, Fakultas Sains dan Matematika, Universitas Diponegoro

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Abstract

Nuclear medicine is a branch of medical science to know the anatomy and physiology of the body. One type of nuclear medicine examination is the examination of bone scanning. According to UNSCEAR (United Nations Scientific Committee on the Effects of Atomic), examination of bone scanning is a type of diagnostic examination which has the largest contribution. Examination of bone scanning using a radiopharmaceutical activity is very high around 320-740 MBq. Because the activity of a given patient is very high, it is necessary to note a half-life in bone biology for radiation protection purposes. Has conducted research on 35 patients in the examination bone scanning to determine the biological half time and the correlation between activity and biological half time. Radioisotopes are used in this examination is Tc99m with farmaka MDP kit (Methylene Diphosponat) with a half-life of 6.03 hours. On examination, the MDP Tc99m radiopharmaceutical is injected intravenously into the patient's arm as much as 15-20 mCi. Furthermore, patients will wait for ± 3 hours and after the enumeration for 10 minutes. Imaging results obtained from the average of the beginning of 627493360 Bq activity and activity after 3 hours of 15290043.495 Bq. Then from the calculation of activity against time t obtained decay constant is effective with an average of 0.271 h1, the mean decay constants of physics-1 and the average 0,115 hours of biological decay constant of 0.156 h-1. The decay obtained from biological half time with an average of 4.434 hours. In this study also found a correlation between the activity after 3 hours with a half-life of -0.94 biology, because the correlation value close to -1 (negative one) then the relationship of these variables have a strong negative correlation. 
Co-Authors Ade Ika Susan Afgani, Jundi Jundullah Agung Dwiyanto Ahmad Mutohar Ainul Ibnu Khotob Alan Tanjung Aji Prastowo Alfian Rizani Ali Khumaeni Anis Nila Kusuma Anugrah Ariyani S. Arif Fahmi Arifah, Dwi Intan Asep Yoyo Wardaya Astrihasna Shafa Bambang Haris Suhartono, Bambang Haris Choirul Anam Choirul Anam AM Diponegoro Chorirul Anam Dewandaru, Ardian Dewantoro, Fajar Dewantoro, Fajar Dhahryan Dhahryan Dini Desita Dwi Siwi Retnoningsih Eddy Prianto Eko Hidayanto Erni Setyowati Fadil Nazir Fajar Arianto Fatkhiyatul Athiqoh G. B. Suparta Gagoek Hardiman Gagoek Hardiman Gani Gunawan Gani Gunawan Hamdani, Muhammad Alif Iza Handayani, Liska Tri Harianja, Bernard Hendrika Liana Sari Heri Sugito Heri Sutanto Hidayatullah, Aydymas Davansyah I Wayan Ari Makmur Ismail Ismail Istifadatun Ni’amah Juhroh, Aminatul Jundi Jundullah Afgani K Sofjan Firdausi K. Sofjan Firdausi Kaka, Susanti Radi Kesawa Sudarsih Ketut Sofjan Firdausi, Ketut Sofjan Khomilia, Crysant Ayu Sufi Kusminarto Kusminarto Kusminarto Kusminarto Kusminarto Kusminarto Kusworo Adi Liska Tri Handayani Maesadji Tjokro Nagoro Maesadji Tjokro Nagoro Maliki Maliki Maria Carizza Pandora Raharjo Masrokan Masrokan Masrokan, Masrokan Michelson Fahrurazi Much Azam Muhamad Adi Muharam Budi Laksono, Muharam Budi Nora Fajria Nur Dwi Prasetyo Pandora Raharjo, Maria Carizza Prasetyo Basuki Pratama, Arthana Setia Priyono, Setyo Purwanto Purwanto Rahmawati, Fatimah Dwi Rini Shintawati Rozanah Rozanah Rusmaharani, Diyah Sihotang, Pandapotan Sugiarto, Oki Suhardi Suhardi Sunarsih Sunarsih Supriyati Supriyati Suryono Suryono Susanti, Audry Nadifa Susila Wardaya, Susila Susilo Susilo Susilo Susilo Susilo Susilo Sutiah Sutiah Sutiyowati Sutiyowati, Sutiyowati Sutrati Melissa Malik Syamsiar, Syamsiar Taqwim S, M Ainut Titi Purwati Tri Wulan Tjiptono Tri Wulan Tjiptono Very Richardina Vitria, Yati Weirna Yusanti Wibowo, Danang Rujito Widiastuti, Ratih Wulandhari Wulandhari Zaenal Arifin