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Fakultas Kedokteran Universitas Hasanuddin, Makassar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health

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Buah Naga (Hylocereus polyrhizus) Meningkatkan Kadar Hemoglobin pada Remaja Putri Thamrin, Halida; Budu, Budu; Nontji, Werna; Sharief, Suchi Avnalurini
Window of Health : Jurnal Kesehatan Vol. 1 No. 3 (Juli, 2018)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (683.231 KB)

Abstract

Remaja putri memiliki risiko tinggi mengalami anemia, hal ini disebabkan hilangnya zat besi saat menstruasi.Remaja putri mempunyai risiko lebih tinggi terkena anemia dibandingkan remaja putra karena remaja putri mengalami menstruasi tiap bulannya dan keinginan untuk mengurangi makan sehingga tubuh kekurangan zat gizi penting seperti zat besi. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian buah naga (Hylocereus polyrhizus) terhadap peningkatan kadar hemoglobin pada remaja putri. Penelitian ini menggunakan desain eksperimental dengan rancangan pretest-posttes with control group. Sampel dalam penelitian ini adalah mahasiswi Prodi DIII Kebidanan. Total sampel yang ditetapkan sebanyak 32 mahasiswi dibagi menjadi 2 kelompok, 16 mahasiswi yang diberikan buah naga (Hylocereus polyrhizus) sebagai kelompok intervensi dan 16 mahasiswi yang diberikan edukasi nutrisi sebagai kelompok kontrol. Pengukuran kadar hemoglobin dilakukan sebelum dan setelah pemberian perlakuan selama 8 minggu, pengukuran periodik dilakukan tiap 2 minggu. Analisa data menggunakan Uji Paired t-test. Hasil penelitian menunjukkan ada pengaruh namun tidak ada perbedaan bermakna pemberian buah naga (Hylocereus polyrhizus) terhadap peningkatan kadar hemoglobin pada remaja putri (P>0,05).
STATUS ANTIOKSIDAN GLUTATION PADA PASIEN TUBERKULOSIS PARU DI BALAI KESEHATAN PARU (BKPM) MAKASSAR Yuniastuti, Ari; Yusuf, Irawan; Massi, Muh Nasrum; -, Budu
Biosaintifika: Journal of Biology & Biology Education Vol 5, No 2 (2013): September 2013
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v5i2.2745

Abstract

AbstrakAntioksidan merupakan senyawa untuk pertahanan tubuh host terhadap radikal bebas. Pada pasien tuberkulosis paru (TB paru), rendahnya antioksidan menyebabkan kerusakan jaringan. Salah satu antioksidan tubuh adalah glutation. Rendahnya glutation berhubungan dengan gangguan sistem imun, sehingga menyebabkan keparahan penyakit pada pasien TB paru. Penelitian ini bertujuan mengetahui kadar glutation plasma penderita tuberkulosis paru. Desain penelitian ini adalah kohort prospektif. Sampel TB paru dipilih di Balai Besar Kesehatan Paru Masyarakat (BBKPM), Makassar yang sesuai dengan kriteria inklusi dan eksklusi dan sesuai kadatangan (consecutive sampling). Dua mililiter darah diambil dari setiap sampel, kemudian dilakukan pemeriksaan kadar glutation dengan ELISA. Hasil penelitian menunjukkan bahwa kadar glutation sampel pasien TB paru sebelum pemberian obat antituberkulosis (OAT) sebesar 0,483830,0344 mM dan setelah pemberian OAT sebesar 0,494650,0371 mM. Setelah pemberian OAT kadar glutation mengalami peningkatan sebesar 2,2% meskipun masih lebih rendah dari kadar glutation normal.AbstractAntioxidants prevent hosts against free radicals. In pulmonary tuberculosis (TB) patients, the low level of antioxidants may cause tissue damage in oxidative hosts. One of antioxidants is glutathione. The poor glutathione level correlates with immune system disorder. The current study aimed to determine glutathione plasma levels in pulmonary tuberculosis patients. The study design was prospective cohort. Pulmonary TB samples were obtained from patients in the Lung Health Centre (BBKPM) in Makassar, and they were selected based on the inclusive and exclusive criteria and on their admittance times (a consecutive sampling technique). Two mililiters of blood was taken from each sample and the glutathione level was examined using ELISA. The study indicated that the glutathione level of the pulmonary TB patients before administered with antitubeculosis drug was 0.483830.0344 mM and after antituberculosis drug was 0.494650.0371 mM. After administration of antituberculosis drug the glutathione level increased by 2.2%, although still lower than normal glutathione level.
Buah Naga (Hylocereus polyrhizus) Meningkatkan Kadar Hemoglobin pada Remaja Putri Thamrin, Halida; Budu, Budu; Nontji, Werna; Sharief, Suchi Avnalurini
Window of Health : Jurnal Kesehatan Vol. 1 No. 3 (Juli, 2018)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (683.231 KB) | DOI: 10.33368/woh.v1i3.41

Abstract

Young women have a high risk of anemia, this is due to iron loss during menstruation. Female teenagers have an increased risk of anemia compared to young men because young women experience menstruation every month and the desire to reduce food so that the body lacks important nutrients such as iron. This study aims to determine the effect of dragon fruit (Hylocereus polyrhizus) on increasing hemoglobin levels in young women. This study used an experimental design with pretest-posttes with control group design. The sample in this research is student Prodi DIII Kebidanan. The total sample of 32 female students was divided into 2 groups, 16 female students were given dragon fruit (Hylocereus polyrhizus) as intervention group and 16 female students who were given nutrition education as control group. Measurements of hemoglobin levels were performed before and after treatment for 8 weeks, periodic measurements were performed every 2 weeks. Data analysis using Paired t-test. The results showed no effect but no significant difference of dragon fruit (Hylocereus polyrhizus) to increase hemoglobin level in female adolescent (P> 0,05).
HUBUNGAN HASIL SUPPLEMENTARY SCALES MMPI-2 TERHADAP HASIL UJI KOMPETENSI PADA ALUMNI KEBIDANAN MAKASSAR PERIODE MARET TAHUN 2018 Yuliati Yuliati; Saidah Syamsuddin; Budu Budu
Jurnal JKFT Vol 5, No 1 (2020): Jurnal JKFT
Publisher : Universitas Muhammadiyah Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31000/jkft.v1i1.2853

Abstract

Various government efforts to reduce Maternal Mortality Rate (MMR), Infant Mortality Rate (IMR), and Under-Five Mortality Rate (UFMR) have been carried out through the Maternal and Child Health program. The research aimed to investigate the relationship between MMPI-2 Supplementary Scales Result and Competency Test Result on Makassar Midwifery Alumni in the Period of March 2018.The research used the observational descriptive method with the cross sectional study design. The research population was all midwifery alumni Health Higher School Mega Rezky Makassar and Midwifery Academy Yapma who attended the competency test in the period of March 2018. Samples were selected using the consecutive sampling technique. The samples were as many as 122 respondents who were divided into two groups namely 61 competent and 61 incompetent respondents. Data were collected MMPI-2 test questionnaire distributed to the respondents and examined by experts. The data analysis used the Chi-square test.The research result of the Supplementary scales distribution indicates the significant scales namely : the Anxiety (A),Ego Strength (ES), Responsibility (Re), Post Traumatic Disorder Keane (PK), and Addiction Admission Scale (AAS). This proves that there is the relationship between MMPI-2 Supplementary Scales Result and competency test result. Key words : Supplementary Scales, Midwifery Alumni, Competency Test.
Risk Assessment in Hereditary Colorectal Cancer Family by Using APC and MSH2 mRNA Gene Expression and Bayesian Analysis Tjahjadi Robert Tedjasaputra; Mochammad Hatta; Muhammad Nasrum Massi; Rosdiana Natzir; Ilhamjaya Patellongi; Marcellus Simadibrata; Ibrahim Labeda; Rina Masadah; Muhammad Luthfi Parewangi; Prihantono Prihantono; Andi Asadul Islam; Agussalim Bukhari; Budu Budu; Rinda Nariswati
The Indonesian Biomedical Journal Vol 12, No 4 (2020)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v12i4.1329

Abstract

BACKGROUND: Some of colorectal cancers (CRCs) are familial, however, heterozygote relatives have approximately 80% lifetime risk of cancer. Risk assessment of CRC’s family could be calculated by direct measurement of mRNA gene expression and Bayesian theorem which is modifying initial background of pedigree risk with additional conditional information. This application has not been reported.METHODS: The cross-sectional translational sequential studies were performed: (1) adenomatous polyposis coli (APC) and MutS homolog (MSH)2 mRNA quantitative RT PCR gene expressions in tissue and whole blood CRC patients; (2) gene expression was determined in matched controls; and (3) pedigree and Bayesian analysis was calculated in the patient’s family of Proband.RESULTS: Fourty CRC and 31 control subjects were enrolled. The mean blood APC level control’s group was 13,261±670 fold-change (fc) and blood MSH2 level was 12,219±756 fc. The cut-off points for hereditary APC was 12,195 fc and MSH2 was 11,059 fc. The mean APC blood level in CRC subject was 11,578±2,638 fc and MSH2 blood level was 11,411±2,912 fc. There were significant differences APC and MSH level between tissue and blood level in CRC. Eight of 40 CRC subjects had a history of familial CRC. Four patients and 10 Probands were available for recurrence risk evaluation of pedigree analysis, RNA PCR quantitative and Bayesian calculation.CONCLUSION: There was determined a cut-off point of hereditary mRNA quantitative expression. The APC and MSH2 levels in CRC subjects were significantly lower than controls. Bayesian analysis allowed for the calculation of relative risk in CRC family members and considered in clinical practice.KEYWORDS: hereditary CRC, APC gene, MSH gene, Bayesian analysis
STATUS ANTIOKSIDAN GLUTATION PADA PASIEN TUBERKULOSIS PARU DI BALAI KESEHATAN PARU (BKPM) MAKASSAR Ari Yuniastuti; Irawan Yusuf; Muh Nasrum Massi; Budu -
Biosaintifika: Journal of Biology & Biology Education Vol 5, No 2 (2013): September 2013
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v5i2.2745

Abstract

AbstrakAntioksidan merupakan senyawa untuk pertahanan tubuh host terhadap radikal bebas. Pada pasien tuberkulosis paru (TB paru), rendahnya antioksidan menyebabkan kerusakan jaringan. Salah satu antioksidan tubuh adalah glutation. Rendahnya glutation berhubungan dengan gangguan sistem imun, sehingga menyebabkan keparahan penyakit pada pasien TB paru. Penelitian ini bertujuan mengetahui kadar glutation plasma penderita tuberkulosis paru. Desain penelitian ini adalah kohort prospektif. Sampel TB paru dipilih di Balai Besar Kesehatan Paru Masyarakat (BBKPM), Makassar yang sesuai dengan kriteria inklusi dan eksklusi dan sesuai kadatangan (consecutive sampling). Dua mililiter darah diambil dari setiap sampel, kemudian dilakukan pemeriksaan kadar glutation dengan ELISA. Hasil penelitian menunjukkan bahwa kadar glutation sampel pasien TB paru sebelum pemberian obat antituberkulosis (OAT) sebesar 0,48383±0,0344 mM dan setelah pemberian OAT sebesar 0,49465±0,0371 mM. Setelah pemberian OAT kadar glutation mengalami peningkatan sebesar 2,2% meskipun masih lebih rendah dari kadar glutation normal. AbstractAntioxidants prevent hosts against free radicals. In pulmonary tuberculosis (TB) patients, the low level of antioxidants may cause tissue damage in oxidative hosts. One of antioxidants is glutathione. The poor glutathione level correlates with immune system disorder. The current study aimed to determine glutathione plasma levels in pulmonary tuberculosis patients. The study design was prospective cohort. Pulmonary TB samples were obtained from patients in the Lung Health Centre (BBKPM) in Makassar, and they were selected based on the inclusive and exclusive criteria and on their admittance times (a consecutive sampling technique). Two mililiters of blood was taken from each sample and the glutathione level was examined using ELISA. The study indicated that the glutathione level of the pulmonary TB patients before administered with antitubeculosis drug was 0.48383±0.0344 mM and after antituberculosis drug was 0.49465±0.0371 mM. After administration of antituberculosis drug the glutathione level increased by 2.2%, although still lower than normal glutathione level.
Edukasi Tentang Stunting Pada Balita Dalam Rangka Peningkatan Pengetahuan Pada Ibu Di Desa Tetewatu Ahmad, Mardiana; Yamin, M.; Budu, Budu; Darmawansyah, Darmawansyah
ARembeN Jurnal Pengabdian Multidisiplin Vol. 1 No. 2 (2023): ARembeN Edisi Desember
Publisher : CV. Ro Bema

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69688/aremben.v1i2.44

Abstract

Stunting (tinggi badan rendah menurut usia) mempengaruhi sekitar seperempat anak usia < 5 tahun di seluruh dunia. Stunting pada anak dapat menyebabkan kurangnya perkembangan kognitif, rentan mendapatkan penyakit dan juga memiliki kekebalan tubuh lebih rendah. Anak-anak dengan stunting dipengaruhi oleh gizi buruk dalam kandungan dan masa kanak-kanak, serta infeksi yang sering terjadi sebelum atau sesudah lahir dan karenanya memiliki risiko lebih besar untuk sakit dan kematian. Kurangnya pengetahuan ibu mengenai kesehatan dan gizi sebelum masa kehamilan serta masa nifas merupakan salah satu penyebab terjadinya stunting. Tujuan pengabdian masyarakat untuk memberikan pendidikan kesehatan melalui penyuluhan tentang stunting. Metode kegiatan pengabmas yaitu pemberian materi kepada 100 orang ibu yang memiliki balita melalui ceramah dan dilakukanya tanya jawab. Untuk mengevaluasi dari keberhasilan kegiatan pengabmas dilakukan penilaian dengan menggunakan kuesioner, penilaian dilakukan sebelum dan seduah pemberian penyuluhan. Hasil kegiatan pengabdian masyarakat didapatkan peningkatan pengetahuan ibu yaitu 98% yang paham tentang stunting dan 2% yang kurang paham tentang stunting. Diharapkan dengan adanya peningkatan pengetahaun ibu dapat mencegah kejadian stunting.
Prenatal Covid-19 on Toddler Development Pasongli, Seri; Budu, Budu; Ahmad, Mardiana; Prihantono, Prihantono; Hidayanti, Healthy; Arsyad, M. Aryadi
JURNAL INFO KESEHATAN Vol 21 No 2 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss2.1176

Abstract

Along with the spread of the COVID-19 pandemic, there has been an increase in reports of confirmed cases of pregnant women with COVID-19. Exposure to the virus in pregnancy can affect the fetus and result in long-term vulnerability to abnormalities in the child's brain development. This study aimed to determine the impact of prenatal Covid-19 on the development of toddlers. The research method uses observational cross-sectional analysis. Secondary data on confirmed Covid-19 mothers were obtained from Prof. RD Kandou General Hospital, Wolter Monginsidi Hospital, and Manado Adventist Hospital. Primary data on toddler development using the KPSP Development Questionnaire instrument were obtained from 10 Community Health Centers in Manado City with a total of 92 respondents for two, 46 respondents were born to mothers with Covid-19 during the prenatal period and 46 toddlers were born to mothers who were not confirmed to have Covid-19 during the prenatal period. The results showed that there was no significant effect with a p-value of 0.562 for toddlers born to Covid-19 mothers on impaired gross motor, fine motor, socialization, and independence, speech, and language development. Based on the results of the study it can be concluded that both toddlers born to Covid-19 mothers and toddlers who were not born to Covid-19 mothers are at risk of experiencing growth disturbances, especially toddlers born during the Covid-19 pandemic because there could be long-term effects that could occur in infants who are exposed to the virus during the prenatal/intrauterine period.
Application of Self-Reflection Using Reflective Journal on Oxytocin Massage Skills in Diploma Three Midwifery Students Arbie, Rina Sulisthia; Budu, Budu; Ahmad, Mardiana; Bukhari, Agussalim; Alasiry, Ema; Usman, Andi Nilawati
JURNAL INFO KESEHATAN Vol 21 No 2 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss2.1180

Abstract

Midwifery is a profession based on women-centered and evidence-based care through the provision of mutually respectful professional relationships and partnerships. To train students' skills, repeated learning is needed, learning can be sourced from experiences such as doing self-reflection by keeping a reflective journal. This research aims to analyze the effect of applying self-reflection using a reflective journal on oxytocin massage skills. This research is an experimental research using a one-group pretest-posttest group design approach, taking samples using a simple random sampling technique. The research population was all level III students in a bivariate analysis using the Friedman ANOVA test. The results showed that the pretest mean value was 59.28 increasing to 79.50 in the first posttest and 83.38 in the second posttest with a p-value <0.05, which means that there is an effect of applying reflective journals using reflective journals on oxytocin massage skills. Having students write reflective journals is a great way for them to learn new concepts. This approach is also useful for lecturers to get feedback on the concepts being studied by students. The use of reflective journals will guide students to analyze what they have and do not know about the material being studied and how to overcome the obstacles encountered so that learning goals are achieved and foster independent learning in students.
Causing Factors of Improvement in the Value of Intranatal Care (INC) on the Passing of the Competence Test of D3 Midwifery Students Firna, Fransiska; Syam, Aminuddin; Budu, Budu; Ahmad, Mardiana; Nontji, Werna; Usman, Andi Nilawati; Niar, Niar
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 2 (2024): Volume 6 Nomor 2 Agustus 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i2.567

Abstract

One of the compulsory courses in the midwife curriculum is the INC course or Maternity care, where this course is a subject that combines theory and practicum, based on the syllabus where the course consists of 5 credits divided into 3 practical credits and 2 theoretical credits, because there was a change in the learning process due to the Covid-19 pandemic, the learning system was carried out during/online which had an impact on the GPA obtained by students and also had an impact on the results of the national competency exam, this can be seen from the decrease in GPA scores and graduation during the pandemic.The aim of this research was to find out the factors that cause a decrease in the value of the INC course on the graduation D3 Midwifery students. The method in this study was retrospective with a crosssectional study design to reveal a causal relationship. There were 69 female students who had not passed the Competency Test as Subjects in the D3 Midwifery study. Analysis to see the relationship used the Chi-Square test. The results of the study found a relationship between learning methods (p-value 0,05 <0,042), learning network (p-value 0,05<0,003)and learning location (p-value 0,05 <0,031)with the value of Intranatal Care to pass the competency test for D3 Midwifery STIKES Bina Generasi Polewali Mandar students. Conclusion, there is a relationship between learned networks, learned methods, learned location are a relationship between learned networks, learned methods, learned location.
Co-Authors Ahmad, Mardiana Ali Nurhadi Aminuddin Syam Anak Agung Gede Sugianthara Anak Agung Istri Sri Wiadnyani Andi Asadul Islam Andi Nilawati Usman Arbie, Rina Sulisthia Ari Yuniastuti Arsyad, Muhammad Aryadi Bukhari, Agussalim Darmawansyah Darmawansyah Ema Alasiry, Ema Firna, Fransiska Healthy Hidayanti Ibrahim Labeda Ilhamjaya Patellongi Irawan Yusuf Irawan Yusuf Jones, Linda Luthfi, Muhammad M. Yamin Marcellus Simadibrata Mochammad Hatta Muh Nasrum Massi Muh. Nasrum Massi Niar, Niar Prihantono Prihantono Prihantono, Prihantono Rina Masadah Rinda Nariswati Rosdiana Natzir Saidah Syamsuddin Seri Pasongli, Seri Suchi Avnalurini Sharief Thamrin, Halida Tjahjadi Robert Tedjasaputra Werna Nontji, Werna Yuliati Yuliati