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All Journal Journal of Islamic Pharmacy Jurnal Biotek Jurnal Dunia Farmasi Majalah Farmasetika JOURNAL LA MEDIHEALTICO Journal La Edusci FORTE JOURNAL Journal of Pharmaceutical and Sciences.
Indra Ginting
Fakultas Farmasi Dan Kesehatan, Institut Kesehatan Helvetia, Medan, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Antibakteri pada Formulasi Sediaan Sabun Mandi Kombucha Bunga Telang (Clitoria ternatea L) sebagai Produk Bioteknologi Farmasi Firman Rezaldi; Siska Dwi Anggraeni; Aris Ma'ruf; Muhammad Andry; Hendri Faisal; Hanafis Sastra Winata; Indra Ginting; Muhammad Amin Nasution
Jurnal Biotek Vol 11 No 1 (2023): JUNI
Publisher : Department of Biology Education of Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jb.v11i1.36906

Abstract

Copyright©2023 Liquid soap with the active ingredient kombucha butterfly pea can limit the growth of Staphylococcus epidermidis and Pseudomonas aeruginosa bacteria. The purpose of this research was to create a liquid bath soap with the active ingredient fermented liquid from the kombucha flower of the butterfly pea plant that inhibits the development of the two test bacteria and to provide objective data on the maximum inhibitory energy at the concentration of the bath soap preparation that can limit the growth of the two test bacteria. This research was experimental and involved making four different types of bath soap preparations: soap base (negative control), liquid body soap formulated with butterfly pea flower kombucha at concentrations of 20, 30, and 40%, and one of the commercial soaps (positive control). Disc diffusion is the method for measuring the average growth of the two test bacteria. Statistical analysis was a one-way ANOVA statistical test at a 95% confidence level, followed by post hoc analysis. The research showed that the liquid body soap with the active ingredient of telang flower kombucha could positively inhibit the growth of the two test bacteria. The concentration of 40% telang flower kombucha bath soap is the best concentration to limit the development of the two test bacteria, with an inhibition zone of 10 mm on Staphylococcus epidermidis, which is in the strong category, and an inhibition zone of 7 mm on Pseudomonas aeruginosa, which is classified as a moderate category.
Uji aktivitas antibakteri kombinasi ekstrak kulit dan biji Pepaya (Carica papaya L.) terhadap bakteri Staphylococcus aureus dan Escherichia coli Indra Ginting; Singgar Ni Rudang; Muhammad Andry; Mayang Sari; Muhammad Amin Nasution
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.262

Abstract

Background;; Infectious diseases suffered by many people include Enterobacter infection from E.coli and skin infections due to S. aureus. One of the plants that have antibacterial properties is papaya like seeds and skin. Objekctives; The purpose of this study was to determine the activity of papaya skin and Seed (Carica papaya L.) extracts against S. aureus and E.coli. Method; The study used experimental method. The extraction used was maceration with ethanol 80%, 60% solvent. 40% and 20%. Antibacterial Activity Test using disc diffusion method and phytochemical screening test on papaya skin extract (Carica papaya L). Result; The results of screening tests on papaya skin extract (Carica papaya L) were positive for alkaloids, saponins, tannins, flavonoids and steroids. The results obtained at 60% ethanol showed that the combined extract of papaya skin and seeds (Carica papaya L) on S. aureus with concentrations (20:80) - (80:20) was 11.9 mm - 15.6 mm. In E. coli with a concentration (20:80) - (80:20) of 9.7 mm - 14.9 mm. Conclusion; The conclusions from the results of research on the combination of papaya skin and papaya seeds (Carica papaya L) of various concentrations inhibited S.aureus bacteria more than E.coli bacteria.
FORMULASI DAN EVALUASI SEDIAAN KRIM PELEMBAB DAN ANTIOKSIDAN EKSTRAK ETANOL BUAH ARA (Ficus racemosa L.) Muhammad Andry; Hanafis Sastra Winata; Indra Ginting; Khairani Fitri; Tetty Noverita Khairani; Ulfa Melyza; Muhammad Amin Nasution
FORTE JOURNAL Vol 4 No 2 (2024): Edisi Juli 2024
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v4i2.932

Abstract

Tumbuhan ara (Ficus racemosa L.) sangat memiliki khasiat sebagai antidiare, antiinflamasi, antioksidan dan lain sebagainya. Antioksidan dalam krim berfungsi sebagai pelembab untuk melindungi kulit dari radikal bebas dengan cara membentuk lapisan lemak tipis di permukaan kulit dan memperlambat kerusakan akibat proses oksidasi. Tujuan penelitian adalah untuk membuat formulasi dari sediaan krim pelembab dengan menggunakan  ekstrak etanol buah ara (Ficus racemosa L.) sebagai pelembab alami kulit dan menentukan konsentrasi terbaik yang memenuhi persyaratan standar Farmakope Indonesia. Penelitian ini dilakukan secara eksperimental. pembuatan ekstrak buah ara dilakukan dengan cara maserasi, konsentrasi ekstrak buah ara ditambahkan ke dalam sediaan formulasi krim 10%, 20% dan 30%. Pengujian sediaan meliputi uji organoleptis, homogenitas, pH, daya sebar, tipe krim, viskositas, iritasi, hedonik dan stabilitas. Analisis data menggunakan uji anova. Hasil menunjukkan sediaan krim pelembab memenuhi syarat evaluasi fisik sediaan yaitu memiliki tekstur semi solid, dengan aroma pewangi krim, warna pada setiap formula berbeda beda, F0 berwarna putih, formula F1 (10%) coklat muda, F2 (20%) coklat pekat, F3 (30%) Coklat hitam. Semua sediaan homogen dan tidak mengiritasi kulit. Memiliki pH berkisar 5-6,3, daya sebar 5-6,7 cm dengan viskositas 9326-13918 Cs, uji stabilitas dengan metode cycling test selama 12 hari memiliki stabilitas yang baik. Hasil rata-rata persentase peningkatan kelembaban pada F0 (17,77%), F1 (35,57%), F2 (49,87%), F3 (51,93%) dan kontrol positif (56,5%). Hasil analisis data menggunakan uji anova menunjukkan ada perbedaan yang signifikan dari ketiga konsentrasi yang diuji. Berdasarkan hasil penelitian dapat disimpulkan sediaan krim pelembab yang diformulasikan dapat melembabkan kulit secara alami, dan disetiap minggunya terjadi peningkatan kelembaban kulit. dan konsentrasi terbaik sediaan krim pelembab yaitu F3 dengan konsentrasi ekstrak 30%.
Co-Authors Aris Ma'ruf Artha Putri Napitupulu Asriwati Amirah Asriwati Asriwati BENNI ISKANDAR Firman Rezaldi Hanafis Sastra Winata Hendri Faisal Heppy Taruli Simanjuntak Ihsanul Hafiz Ismail Effendy Jefri Naldi Khairani Fitri Leli Masliana Leny, Leny Mayang Sari Muhammad Amin Nasution Muhammad Amin Nasution Muhammad Andry Rachel Anastasia R Hutabarat Rudang, Singgar Ni Singgar Ni Rudang Siska Dwi Anggraeni Siti Fatimah Hanum Sondang Ginting Suci Ramadayanti Suprianto Suprianto Tetty Noverita Khairani Tiary N Sitohang Tiwanto Dakhi Ulfa Melyza Winata, Hanafis Sastra