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Immunoinformatics Analysis of SARS-CoV-2 Isolated from Karst of Bats in Malang, Indonesia Moch Irfan Hadi; Aditya Sukma Prawira; Khuliyah Candraning Diyanah; Dedy Suprayogi; Soedjajadi Keman; Yudied Agung Mirasa; M Yusuf Alamudi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14805

Abstract

In December 2019, cases of mysterious pneumonia were first reported in Wuhan, Initially, the diseasewas temporarily named as 2019 novel coronavirus (2019-nCoV), then WHO announced a new name onFebruary 11, 2020, namely Coronavirus Disease (COVID-19) which is caused by a virus Severe AcuteRespiratory Syndrome Coronavirus-2 (SARS-CoV-2). This virus can be transmitted from person toperson and has spread widely in China and more than 190 other countries and territories. Meanwhile inIndonesia, up to September 2020, 203 thousand cases of COVID-19 were found and 8336 deaths. Batsact as important disease reservoirs for various etiologic agents of disease that can be transmitted betweenspecies, infecting humans and mammals, both domestic and wild. The purpose of this study was to analyzeSARS-CoV-2 immunoinformatics in bats in Karst Malang Indonesia as the basis for making SARS-CoV-2vaccines. This research method is SARS-CoV-2 amino acid bats in Karst Malang, Indonesia analyzed byimmunoinformatics. From the research results, it was found that SARS-CoV-2 protein from Malang Karstbats were antigen, non-allergen and non-toxin, so that they could be used as vaccine candidates, diagnostickits and immunotherapy.
Optimalisasi Pengetahuan Tentang Menstruasi Pada Siswa Putri Kelas 5 dan 6 SDN Janti 1 Waru Sidoarjo Dengan Pendekatan PAR Mei lina Fitri Kumalasari; Nova Lusiana; Estri Kusumawati; Dedy Suprayogi; Moch. Irfan Hadi
Nusantara Journal of Community Engagement Vol. 1 No. 1 (2020): MARET
Publisher : Lembaga Penelitian dan Pengabdian (LP2M) Sekolah Tinggi Agama Islam Cendekia Insani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.2020/njce.v1i1.3664

Abstract

Anak perempuan yang mengalami menarche (menstruasi pertama) pada usia yang muda merasa belum siap untuk menghadapi menstruasi pertamanya sehingga dapat menimbulkan dampak takut, bingung, minder, merasa tidak normal dan panik. Pengabdian masyarakat ini bertujuan untuk optimalisasi pengetahuan tentang menstruasi pada siswa putri kelas 5 dan 6 di SDN Janti 1. Metode kegiatan yang dilakukan adalah dengan pendekatan PAR. Didapatkan hasil bahwa dari 89 siswa putri, terdapat 40 siswa putri (44,94%) yang sudah mendapatkan menstruasi. Siswa putri tersebut mengalami menarche pada usia 10 sampai dengan 12 tahun. Terdapat 22 siswa putri (55%) yang mengalami dismenorea dan belum mengetahui apa yang harus dilakukan apabila mengalami keluhan tersebut. Materi diberikan dengan media powerpoint dan video. Siswa putri kelas 5 dan 6 SDN Janti 1 aktif dalam kegiatan dengan memberikan pertanyaan-pertanyaan dan saling berbagi pengalaman.
Analisis Kariometric Akibat Pemberian Variasi Dosis Aspartam pada Perkembangan Fetus Mencit (Mus Musculus L.) Esti Novi Andyarini; Nova Lusiana; Ika Mustika; Estri Kusumawati; Sri Hidayati; Moch Irfan Hadi; Risa Purnamasari; Dedy Suprayogi
Biotropic : The Journal of Tropical Biology Vol. 3 No. 2 (2019): Biotropic, Volume 3 Nomor 2, 2019
Publisher : Program Studi Biologi, Fakultas Sains dan Teknologi, Universitas Islam Negeri Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1000.714 KB) | DOI: 10.29080/biotropic.2019.3.2.86-95

Abstract

Aspartame is safe for consumption according to the prescribed ADI, but this artificial sweetener is not nutritious or does not contain calories so it is not recommended to be consumed during pregnancy. This study was to analyze cariometric effect of aspartame doses in the development of fetal mice (Mus muculus L.). The type of research used was experimental laboratory research on 24 adult mice with 4 treatment groups, control, aspartame dose 13 mg / Kg BB, 39 mg / Kg BB and 78 mg / Kg BB. Data was analyzed using SPSS 16 with one way ANOVA. Based on the results of the study there were changes in the number and weight of the fetus due to aspartame doses, there was no change in fetal length due of aspartame dose variations. Consumption of aspartame during pregnancy should be avoided because it can cause teratogenic effects. For further research, it is necessary to observe the morphology and histology of the fetus which is expressed by aspartame to determine the types of congenital abnormalities.
Analisis Pola Persebaran Pencemaran Air Tanah di Sekitar Penambangan Sumur Minyak Tua Desa Wonocolo, Kedewan, Bojonegoro: Analysis of Groundwater Pollution Distribution Patterns Around the Mining of Old Oil Wells Wonocolo Village, Kedewan, Bojonegoro Subariswanti; Abdul Hakim; Dedy Suprayogi
Jurnal Teknik Sipil dan Lingkungan Vol. 6 No. 2: Agustus 2021
Publisher : Departemen Teknik Sipil dan Lingkungan, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jsil.6.2.133-142

Abstract

Wonocolo Village is a traditional old oil well mining tourism area in Kedewan District, Bojonegoro Regency. This existence affects water quality because it is one of many factors causing groundwater pollution. The purpose study is to determine the distribution pattern of pollution such as iron, manganese, and zinc due to oil mining. Moreover, the study predicts the pattern of distribution of pollution in groundwater over a certain period of time. The method used for this study is groundwater modeling (MATLAB). Thus, determination of sampling based on SNI 6989.58:2008 with 3 (three) sampling points. The determination of the distribution pattern uses the parameters such as Iron, Manganese, and Zinc. The simulation results of the 2-dimensional distribution model and in the range in the next 18 years and 50 years. The prediction result for iron content is still in good condition. Meanwhile for manganese content and zinc content will be polluted after 50 years with a detected distance of ± 1150 m and ± 1400 m respectively from the contaminant source point.
Management of Sars-Cov-2 Medical Waste Against a Covid19 Pandemic in Indonesia: A Literature Review Moch. Irfan Hadi; Mirna Widiyanti; Mei Lina Fitri Kumalasari; Muhammad Yusuf Alamudi; Dedy Suprayogi
JURNAL KESEHATAN LINGKUNGAN Vol. 12 No. 4 (2020): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v12i4.2020.244-253

Abstract

Introduction: SARS-CoV-2 RNA transmission in wastewater has a risk of fecal transmission of SARS-CoV-2 to humans and the environment. Despite the increasing number of cases in almost all areas in Indonesia, the study to review and evaluate waste management resulted from medical facilities is still limited and less explored. This literature review aims to analyze the applicability of WHO guidelines on wastewater management to be implemented in Indonesia. Scientific papers were collected from several electronic databases such as PubMed, PLoS, Researchgate, WHO, Elsevier, Science, SARS-CoV-2, Covid19, and wastewater. The articles were selected based on the inclusion criteria that use SARS-CoV-2, Covid19, and wastewater as the main variables observed. The articles published before 2013 were excluded from this review. Discussion: Wastewater monitoring of SARS-CoV-2 within medical and health facilities is implemented to identify the virus's presence as the causative agent of Covid19 disease, which contaminated the environment and society. The results of the analysis in wastewater can be used to determine the infection control in health facilities while also beneficial in formulating the monitoring of environmental impacts caused by the waste. These efforts would support policies or interventions based on public health by applying social distances, locking, quarantine areas that aim to break the Covid19transmission. Conclusion: Briefly, by considering the urgency of Covid19 pandemic containment and control measures of transmission in health facilities, population and environment. It is a waste management guideline that is highly required to be implemented based on public health aspects.
USE OF PHOSPHORIC ACID AS BIOADSORBENT ACTIVATOR OF KETAPANG LEAVES (Terminalia sp.) TO REDUCE RHODAMINE B CONTAMINANTS Nadya Hasna; Dedy Suprayogi; Abdul Hakim
Konversi Vol 10, No 2 (2021): Oktober 2021
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/k.v10i2.11072

Abstract

Ketapang contains tannin and phenolic compounds which are known to absorb metals and pollutants in the air. The purpose of this study was to determine the effectiveness of the biadsorbent from ketapang leaves (Terminalia sp.) on the adsorption of Rhodamine B dye without activation and with activation by 10% phosphoric acid. The study began with testing the variation of mass, time, and concentration of Rhodamine B by ketapang leaves. Then the adsorption process was carried out using a batch system and the concentration of the filtrate was measured using a UV-Vis spectrophotometer. Followed by the isotherm analysis of Freundlich and Langmuir. The results showed that the bioadsorbent ability of ketapang leaves without activation or with activation by 10% H3PO4 in terms of mass variation, contact time, and Rhodamine B concentration were 300 mg, contact time was 90 & 120 minutes, and Rhodamine B concentration was 10 mg/l. - 30 mg/l. The maximum bioadsorbent capacity of ketapang leaves (Qm) without activation was 3.7037 mg/g, while that of ketapang leaves with phosphoric acid activation was 1.0673 mg/g. The adsorption model used by the ketapang leaf bioadsorbent is the Freundlich isotherm where the R2 value close to 1 is 0.9573.
Handling Solutions for Electronic Waste (E - Waste) in Indonesia Dedy Suprayogi
Al-Ard: Jurnal Teknik Lingkungan Vol. 1 No. 2 (2016): Maret
Publisher : Department of Environmental engineering, Faculty of Science and Technology, Islamic State University Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (363.45 KB) | DOI: 10.29080/alard.v1i2.115

Abstract

Any changes always take effect to the environment either positive or negative, it is no exception developments in technology. In addition to bringing benefits to the human development, technology has always had a negative impact, actually thrash or waste from obsolete technology as the results of the process productions or side product. The mobile phones waste is one of the electronic waste that need to be awareness. Electronic waste processing in particular mobile phones as one of the new problems in the waste management, and it will be an ice mountain problem for developing countries because generally they have limited technology, insufficiency of financial and lack of human resources in the management of electronic waste that electronic trash left to accumulate for granted. Indonesia as a developing country need to strengthening regulatory, economic support and technology transfer of electronic waste management from developed countries to suppress pollution caused by electronic waste disposal carelessly.
Analisis Kualitas Air Sungai Bawah Tanah Gua Ngerong, Kecamatan Rengel, Tuban Dedy Suprayogi; Sulistiya Nengse; Abdul Hakim
Al-Ard: Jurnal Teknik Lingkungan Vol. 5 No. 1 (2019): September
Publisher : Department of Environmental engineering, Faculty of Science and Technology, Islamic State University Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.264 KB) | DOI: 10.29080/alard.v5i1.748

Abstract

Fulfillment of water quality requirements is absolutely necessary to fulfill primary human needs, especially drinking water and clean water sources, both in quantity and quality. Study of the underground caverns found the fact that in terms of quantity of water availability in the reservoir is able to meet the needs of residents of the Rengel District, but qualitatively not yet known the water quality in the reservoir. The purpose of this study was to measure the water quality of underground caves in caves which include temperature, turbidity, TDS, DO and pH. The method used in this study is a qualitative method to measure the value of water quality. The research sample was taken with three repetitions for data validity. The sampling location is the underground cave system with a length of 1 km, sample points include dark zone 1, dark zone 2, dark zone 3, and dim zone. Measurements were taken in the laboratory. The results of the study showed that the average values for temperature, turbidity, TDS, DO and pH were 26.7; 1,9; 348.2; 1,6; and 7.1. The conclusion obtained from this study is that all indicators except DOs meet environmental quality standards set by the government.
Fitoremediasi Tanaman Apu-Apu (Pistia Stratiotes) terhadap Kadar Logam Zn Berdasarkan Variasi Jumlah Tanaman Laili Oktaviani; Widya Nilandita; Dedy Suprayogi
Al-Ard: Jurnal Teknik Lingkungan Vol. 6 No. 1 (2020): September
Publisher : Department of Environmental engineering, Faculty of Science and Technology, Islamic State University Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/alard.v6i1.981

Abstract

Zn merupakan logam berat yang banyak digunakan untuk memenuhi kebutuhan industri. Meningkatnya penggunaan Zn menyebabkan pencemaran air. Untuk mereduksi hasil buangan dari industri yang menghasilkan Zn dapat dilakukan dengan cara teknik fitoremediasi. Pada penelitian ini, fitoremdiasi yamg dilakukan yaitu dengan memanfaatkan tanaman Apu-Apu (Pistia stratiotes) sebagai tanaman fitoremediator. Penelitian ini dilakukan dengan tujuan untuk mengetahui efisiensi penyerapan logam berat Zn oleh tanaman Apu-Apu dengan variasi jumlah tanaman yang berbeda. Variasi jumlah tanaman yang digunakan yaitu 10 dan 15 tanaman dengan waktu tinggal selama 10 hari dan dengan konsentrasi awal 11,02 ppm. Hasil penelitian ini menunjukkan bahwa pada reaktor B memiliki efisiensi removal logam berat Zn sebesar 83,85% dan pada reaktor C memiliki efisiensi removal sebesar 79,50%.Kata Kunci: Logam Zn, Fitoremediasi, Pistia stratiotes, Sistem Batch
Analisis Uji Toksisitas Akut Logam Cu Terhadap Artemia salina dan Daphnia magna Dedy Suprayogi; Sri Hidayati L; M.Ratodi; Farhana Fitri Ardilla
Al-Ard: Jurnal Teknik Lingkungan Vol. 7 No. 1 (2021): September
Publisher : Department of Environmental engineering, Faculty of Science and Technology, Islamic State University Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/alard.v7i1.1333

Abstract

Water pollution can become dangerous if consumed. River could be polluted with some materials namely heavy metal of chopper (Cu). Heavy metals that are accidentally consumed by human body through the skin surface, some through the respiratory or digestive tract and then accumulate in the body over time. To make an early detection of heavy metal and water quality in water bodies, some animals or plants were used. Several types of crustaceans such as Artemia salina and Daphnia magna or commonly referred to as bio indicators. This study analyze comparison of acute toxicity test that represented by LC50 value of Cu in Artemia salina and Daphnia magna. From the research result it was found that Artemia salina and Daphnia magna gave a toxic effect with LC50 values of 11.78 ppm and 7.87 ppm, respectively.