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Journal : NurseLine Journal

The Difference of Eosinophil Amount in Tuberculosis Patients with and without Soil-Transmitted Helminths Co-infection in Panti District, Jember Yunita Armiyanti; Nisrina Salsabila Firmansyah; Angga Mardro Raharjo; Muhammad Ali Shodikin; Enny Suswati; Dini Agustina
NurseLine Journal Vol 5 No 1 (2020): May 2020
Publisher : Faculty of Nursing, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/nlj.v5i1.16729

Abstract

Tuberculosis is one of the world's health problems even in Indonesia. The immune response that needed to deal with TB can be influenced by other infections, such as helminth infection. The helminth infections induce Th2 immune responses and eosinophilia to eliminate these pathogen. Meanwhile, the Th2 response and eosinophilia can also suppress the Th1 immune response which is very important to eliminate the bacterium M. tuberculosis and make a negative impact on the success of TB therapy. Thus, the eosinophil profile can describe the immune response in TB patients with helminth co-infection. This study aims to determine the prevalence of helminthiasis in TB patients and determine the differences in eosinophil amount in tuberculosis patients with and without helminth co-infection. This study was an observational analytic study with a cross-sectional design conducted at Puskesmas Panti in August 2019-January 2020 using fecal and blood samples from 24 research subjects. Helminth co-infection status was obtained from fecal examination with sedimentation and flotation methods while the number of eosinophils was obtained from leukocyte counts. Data analysis used the Mann Whitney U test to determine differences in the number of eosinophils in the two groups. The results showed there was no difference in the number of eosinophils in TB patients with helminth co-infection and without helminth co-infection (p> 0.05). There is no typical picture of the number of eosinophils in both groups so that eosinophils cannot describe the immune response that arose in TB patients with helminth co-infections in Panti district, Jember.
Co-Authors Achmad Ma'ruf Fauzi Adelia Handoko Adilah Julinar Irianti Agustin, Aisyiyah Alviana Ainindya Pasca Rachmadiani Aisyiyah Alviana Agustin Anaditya Wahyu Kumudhaningsih Angga Mardro Raharjo Angga Mardro Raharjo, Angga Mardro Annisa Nadhifa Witanto Bagus Hermansyah Bellynda, Wynne Billy Jusup Kurniawan Cholis Abrori, Cholis Cicih Komariah Desi Dwi Wisudanti Desie Dwi Wisudanti Diana Chusna Mufida Dina Luthfiyah Dini Agustina Dissa Yulianita Suryani Dita Diana Parti Dwita Aryadina Dwita Aryadina Rachmawati Ekvan Danang Setya Pramudito Ellen Ocktavironita Elvia Rahmi Marga Putri ENNY SUSWATI Erfan Efendi Eva Deswinta Maharani Firman Pratama Andraputra Gianevan, Nicholas Jirezra Hadi Khoiruddin, Mukhammad Arif Ida Srisurani Wiji Astuti Ika Rahmawati Sutejo Inke Kusumastuti Irawan Fajar Kusuma Kristianningrum Dian Sofiana Kurnia Elka Vidyarni Laila Rizqi Kurniawati Lailatis Shofia Marchianti, Ancah C N Muhammad Alif Taryafi Nexia Nevarachell Onny Amirsyah Nisrina Salsabila Firmansyah Nurlaila Ayu Purwaningsih Oessi Salsabila Pradewi, Ranny Tandria Pramono, Anang Putra Uta, Diego Rafi Putri Prameswari Nastiti Ayu Qintar Layallia Faza Rahami, Nahla Ahmad Ramadhanty, Mira Haninda Renny Suwarniaty Rini Riyanti Rosita Dewi Rumastika, Nindya Shinta Safitri, Athiyah Naura Saputra, Antonius Dwi Semita, I Nyoman Sheilla Rachmania, Sheilla Shofia, Lailatis Sudarmanto, Yohanes Susanto Nugroho Tohari, Achmad Ilham Tsintani Nur Aristiana Wahidah Nur Indasyah Widhiasari Normaningtyas Wiwien Sugih Utami Wiwin Sugih Utami Yasmin Auralia Putri Yudha Nurdian Yuli Hermansyah Yuli Hermansyah Yuli Hermansyah, Yuli Yuli Lusiana Sari Yunita Armiyanti