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All Journal PRoMEDIA JURNAL FARMASIMED (JFM) Majalah Farmasetika Jurnal Ners Indonesia Natural Research Pharmaceutical Journal (INRPJ) JURNAL USM LAW REVIEW Berdikari : Jurnal Pengabdian kepada Masyarakat Pharmacy Action Journal KAMI MENGABDI Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran Asian Journal of Social and Humanities
Diana Laila Rahmatillah
Fakultas Farmasi Universitas 17 Agustus 1945 Jakarta
Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Other

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Evaluasi Terapeutik Outcome dan Mortalitas Pasien Jantung Pasca Vaksin COVID-19 di Rumah Sakit Elta Oktariana; Diana Laila Ramatillah; Naglaa Gamil Shehab
Jurnal Ners Vol. 10 No. 4 (2026): OKTOBER 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i4.62572

Abstract

Penyakit kardiovaskular merupakan salah satu penyebab utama kematian di dunia, dengan lebih dari 17,8 juta kematian setiap tahun. Pandemi COVID-19 menimbulkan perhatian khusus pada pasien dengan penyakit jantung karena memiliki risiko komplikasi yang lebih tinggi. Vaksinasi COVID-19 menjadi salah satu strategi utama untuk menurunkan dampak infeksi, tetapi keamanan dan manfaatnya pada pasien jantung masih perlu dikaji. Tujuan penelitian ini bertujuan mengetahui hubungan therapeutic outcome dan mortalitas pada pasien jantung pascavaksinasi COVID-19 di beberapa rumah sakit di Kalimantan Tengah. Metode penelitian menggunakan data rekam medis pasien penyakit jantung yang mendapatkan vaksin COVID-19 selama periode 2020–2025. Hasil terdapat perbedaan therapeutic outcome yang signifikan sebelum dan sesudah vaksinasi berdasarkan tekanan darah sistolik (p = 0,000), diastolik (p = 0,002), dan kadar kolesterol (p= 0,000). Analisis Kaplan-Meier dan Log-Rank menunjukkan tidak terdapat hubungan signifikan antara vaksinasi COVID-19 dan mortalitas (p = 0,399). Kesimpulan vaksinasi COVID-19 berhubungan dengan perbaikan therapeutic outcome pada pasien jantung dan tidak menunjukkan hubungan signifikan dengan peningkatan mortalitas.
Evaluation of ACEI Use on Kidney Function and Lipid Profile in Outpatient Hypertension Patients at Raden Mattaher General Hospital, Jambi, Jambi Province Onesis Novita Dewi; Diana Laila Ramatillah; Kashif Ullah Khan; Ida Paulina Sormin
Jurnal FARMASIMED (JFM) Vol 9 No 1 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v9i1.3756

Abstract

Hypertension is a global health problem that increases the risk of cardiovascular disease and impaired kidney function. The use of Angiotensin-Converting Enzyme Inhibitors (ACEIs) is widely recommended due to their effectiveness in lowering blood pressure and providing renoprotective effects. However, variations in therapeutic responses, particularly in kidney function and lipid profile, require further evaluation. This study aimed to analyze the association between ACEI use and kidney function and lipid profile in outpatient hypertensive patients. This study employed an observational analytic design with a retrospective approach based on medical record data of hypertensive patients receiving ACEI therapy. Samples were selected based on inclusion criteria, with complete data on kidney function (eGFR, serum creatinine, and BUN) and lipid profile (total cholesterol, LDL, HDL, and triglycerides). Data were analyzed using descriptive statistics and inferential analysis using the Kruskal–Wallis test. The results showed that the majority of patients were in the late elderly age group (56–65 years) (39.6%) and predominantly male (62.1%). significantly associated with serum creatinine (p = 0.000), while no significant associations were found with eGFR (p = 0.206) and BUN (p = 0.170). In addition, the duration of ACEI use showed no significant association with eGFR (p = 0.089), but was significantly associated with serum creatinine (p = 0.001) and BUN (p = 0.009). Regarding lipid profiles, both the type and duration of ACEI use were significantly associated with all parameters, including total cholesterol, LDL, HDL, and triglycerides (all p = 0.000). In conclusion, ACEI therapy shows differential associations with kidney function and lipid profile parameters in hypertensive patients. Therefore, regular monitoring of renal function and lipid profiles is recommended to optimize therapeutic outcomes and prevent potential metabolic and renal complications.
Medication Adherence, Family Support, and Cost-effectiveness in Type 2 Diabetes Mellitus Management: A Narrative Review Dwike Ardatillah; Diana Laila Ramatillah; Kashif Ullah Khan
Jurnal FARMASIMED (JFM) Vol 9 No 1 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v9i1.3766

Abstract

Background: Type 2 diabetes mellitus (T2DM) is a chronic disease with a high prevalence that requires lifelong treatment, resulting in a substantial economic burden. Medication adherence, family support, and cost-effectiveness are essential pillars for the successful management of T2DM. Objective: This narrative review aimed to analyze the scientific evidence regarding the factors influencing medication adherence, the role of family support in the management of type 2 diabetes mellitus, and the cost-effectiveness of various antidiabetic therapies. The review synthesized evidence from 50 published research articles. Methods: A narrative review was conducted using 50 scientific articles retrieved from the PubMed, PubMed Central, and Google Scholar databases. The articles were published between 2020 and 2026 and included studies investigating medication adherence, family support, factors affecting therapeutic success, and Cost-effectiveness Analysis (CEA) of antidiabetic therapies. Results: The findings demonstrated that medication adherence was significantly associated with improved clinical outcomes (p < 0.05). Pharmacist-led counseling and patient education were shown to be effective in reducing blood glucose levels. Family support was also significantly associated with medication adherence (OR = 7.650; p = 0.003). Pharmacoeconomic evidence indicated that metformin was the most cost-effective antidiabetic therapy compared with other treatment regimens. Furthermore, the metformin–glimepiride combination demonstrated a lower Average Cost-effectiveness Ratio (ACER) than the acarbose–glimepiride combination. Conclusion: The management of type 2 diabetes mellitus requires a holistic approach that integrates strategies to improve medication adherence through education and pharmacist counseling, while strengthening family support to achieve optimal clinical outcomes. In addition, selecting cost-effective pharmacological regimens is essential to optimize both therapeutic effectiveness and healthcare resource utilization.
Medication Adherence, Family Support, and Cost-Effectiveness in Type 2 Diabetes Mellitus Management: A Narrative Review Vintha Sari Uly; Diana Laila Ramatillah; Kashif Ullah Khan
Jurnal FARMASIMED (JFM) Vol 9 No 1 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v9i1.3783

Abstract

Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease with a continuously increasing global prevalence. Successful T2DM management largely depends on patients' adherence to pharmacological therapy and overall disease management. However, medication adherence remains a major challenge, often resulting in failure to achieve glycemic targets, an increased risk of complications, and reduced quality of life. Pharmacists play a crucial role in improving medication adherence and clinical outcomes through various pharmaceutical care services, including pharmacist counseling, Medication Therapy Management (MTM), telepharmacy, home pharmacy care, and patient health education. Objective: This narrative review aimed to evaluate the impact of pharmaceutical care services on medication adherence and clinical outcomes among patients with T2DM based on published scientific evidence. Methods: A comprehensive electronic literature search was conducted using several international and national scientific databases, including PubMed, PubMed Central (PMC), Google Scholar, and ScienceDirect. A total of 50 eligible articles published between 2021 and 2026 were included in this review. Results: The findings demonstrated that pharmaceutical care services significantly improved medication adherence and clinical outcomes, as reflected by reductions in glycated hemoglobin (HbA1c), fasting blood International License. glucose (FBG), and random blood glucose (RBG) levels. Pharmaceutical care interventions combined with regular follow-up through telepharmacy or home pharmacy care were found to be more effective than conventional patient education alone. Conclusion: The evidence highlights that the active involvement of pharmacists is an essential component of T2DM management, contributing substantially to improved clinical outcomes and long-term therapeutic success.
Patterns And Appropriateness Of Dyslipidemia Treatment Among Patients With Type 2 Diabetes Mellitus At A Naval Hospital In Jakarta, Indonesia Atisi; Diana Laila Ramatillah; Kashif Ullah Khan
Jurnal FARMASIMED (JFM) Vol 9 No 1 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v9i1.3881

Abstract

Dyslipideimia is a coimmoin meitaboilic abnoirmality amoing patieints with typei 2 diabeiteis meillitus (T2DM) and cointributeis toi increiaseid cardioivascular risk. Lipid-loiweiring theirapy, particularly statins, plays an impoirtant roilei in thei manageimeint oif dyslipideimia; hoiweiveir, treiatmeint patteirns and approipriateineiss may vary in roiutinei clinical practicei. This study aimeid toi deiscribei thei patteirns oif dyslipideimia treiatmeint and eivaluatei treiatmeint approipriateineiss amoing patieints with T2DM at Dr. Mintoihardjoi Naval Hoispital, Jakarta, Indoineisia. This oibseirvatioinal analytical study useid a reitroispeictivei croiss-seictioinal deisign. Data weirei oibtaineid froim thei meidical reicoirds oif 200 patieints with T2DM. Dyslipideimia treiatmeint was classifieid intoi statin, noin-statin, coimbinatioin oif statin and noin-statin, and noi lipid-loiweiring theirapy. Treiatmeint approipriateineiss was classifieid as approipriatei oir inapproipriatei accoirding toi thei preideifineid criteiria useid in thei study. Data weirei analyzeid using IBM SPSS Statistics veirsioin 27.0 and preiseinteid as freiqueincieis and peirceintageis. Oif 200 patieints with T2DM, 105 (52.5%) reiceiiveid statin theirapy, 14 (7.0%) reiceiiveid noin-statin theirapy, 23 (11.5%) reiceiiveid coimbinatioin theirapy, and 58 (29.0%) reiceiiveid noi lipid-loiweiring theirapy. Oiveirall, 165 patieints (82.5%) had treiatmeint classifieid as approipriatei, wheireias 35 (17.5%) had treiatmeint classifieid as inapproipriatei. Statins weirei thei moist freiqueintly useid lipid-loiweiring theirapy amoing patieints with T2DM. Moist patieints reiceiiveid treiatmeint classifieid as approipriatei; hoiweiveir, neiarly oinei-third reiceiiveid noi lipid-loiweiring theirapy and 17.5% had treiatmeint classifieid as inapproipriatei. Peirioidic eivaluatioin oif lipid-loiweiring theirapy is theireifoirei impoirtant toi suppoirt oiptimal dyslipideimia manageimeint in patieints with T2DM.
APA ITU KOLESTEROL: PENTINGNYA PENCEGAHAN KOLESTEROL PADA USIA REMAJA DI SMA NEGERI 15 JAKARTA UTARA Topan Dirgantara; Diana Laila Ramatillah; Siti Maryam; Dhynne Risha Fitri; Widiawati Widiawati; Anggie Andalika; Diren Handayani; Afriady Nuur Muhammad; Fajar Ria Lestari; Indriani Alviandini; Farras Khalda Salsabila
Pharmacy Action Journal Vol 3, No 2 (2024): 2024
Publisher : UNIVERSITAS 17 AGUSTUS 1945 JAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/paj.v3i2.7246

Abstract

Kolesterol adalah sterol yang paling dikenal oleh masyarakat. Kolesterol merupakan bahan antara pembentukan sejumlah steroid penting, seperti asam empedeu, asam folat, hormon-hormon korteks adrenal, estrogen, androgen, dan progesteron. Pengobatan hiperkolesterolemia dapat dilakukan dengan farmakologis dan non farmakologis. Penyuluhan ini dilakukan kepada responden yang berada di SMA Negri 15 jakarta Utara, sebanyak 34 orang. Kegiatan penyuluhan ini dilakukan oleh Mahasiswa Apoteker Universitas 17 Agustus 1945 Angkatan 49 Kelas Apoteker A, dengan melibatkan mahasiswa sebanyak 10 orang. Penyuluhan ini bertujuan untuk memberikan pemahaman terkait kolesterol dan edukasi mengenai pentingnya pencegahan kolesterol yang tinggi pada usia remaja. Berdasarkan hasil pre-test dan post-test yang dilakukan, terlihat bahwa peserta penyuluhan telah mampu menerima pengetahuan serta memahami mengenai pentingnya pencegahan kolesterol yang tinggi pada usia remaja, yang dapat dilihat dari adanya peningkatan pada persentase nilai post-test dan nilai N-Gain sebesar 0,91.
Co-Authors Abdul David Pongsapan Ade Kurniatu Afriady Nuur Muhammad Ahmad Rofii Ajeng Anggraini Pangestu Angel Maria Simatupang Angela Imelda Cahaya Anggie Andalika Asieh Nurmaniarsieh Atisi Bryghita Suryanata Desmarini I S Dhynne Risha Fitri Dinar Ayu Chandra Agustin Diren Handayani Dwike Ardatillah Elma Fania Agus Elta Oktariana Ezra Alvira Setiawan Faisal Faisal Fajar Ria Lestari Farras Khalda Salsabila Fezi Kendri Gian Fisoma K Hanna P S I Made Deny Sapta Giri Ida Paulina Sormin Indriani Alviandini Kartika Bunga Rezky Kashif Ullah Khan Kashif Ullah Khan Kashif Ullah Khan Kashif Ullah Khan Kashif Ullah Khan Kharida Zainatus Salamah Khoirunnisa Khoirunnisa Komang Trisna Dewi Kurnia Hendi Prayogi M Fajri Hidayat Maha A P Marco Develsio Melisa Ayu Saputri Nadia Mahmudah Naglaa Gamil Shehab Ni Kadek Putri Krismawati Ni Made Sintya Dewi Ni Nengah Dewi Antaryani Ni Putu Rischa Christiani Nindita Yoan Nirma Nirma Noorjannah Noorjannah Nor Redha Rizky Norman Dyanto Novita Hijriah Novitayanti Pongsapan Onesis Novita Dewi Petra Agita Putri Srikandi Rachel Ayu Nastiti Rajes Khana Rangki Astiani Ria Anggraeni Sharon Manona Siti Maryam Sri Endah Susilowati Sri Lucyanawati Stefanus Lukas Topan Dirgantara Tuti Widyaningrum Ulfah Fatmala Rizky Vinsensia Asahi Sulan Langit Vintha Sari Uly Wahyu Setya Wibawa Widiawati Widiawati Wijonarko, Panji