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All Journal Jurnal Keperawatan dan Kesehatan Masyarakat CENDEKIA UTAMA THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Jurnal Surya Medika Jurnal Keperawatan Silampari Herb-Medicine Journal Jurnal Kesehatan Jurnal Analis Medika Biosains (JAMBS) Jurnal Biomedika Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Science Midwifery Borneo Journal of Medical Laboratory Technology Indonesian Journal of Global Health research MAHESA : Malahayati Health Student Journal Prosiding Seminar Nasional Hasil-hasil Penelitian dan Pengabdian Pada Masyarakat Ulil Albab CHI JOURNAL OF Community Health Issues Indonesian Journal of Global Health Research
Retno Sulistiyowati
Universitas Muhammadiyah Purwokerto
Religion Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Perbandingan Kadar Ureum dan Kreatinin Pada Prolanis Lansia Diabetes Mellitus Tipe 2 Berdasarkan Jenis Kelamin di UPTD Puskesmas Banjarmangu 1 Wiwit Rahmawati; Umi Solikhah; Retno Sulistiyowati; Minto Rahaju
ULIL ALBAB : Jurnal Ilmiah Multidisiplin Vol. 1 No. 10: September 2022
Publisher : CV. Ulil Albab Corp

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Abstract

Prevalensi kasus kronis khususnya pada lansia semakin meningkat. Pemerintah merancang Prolanis sebagai Program Pengelolaan Penyakit Kronis khususnya penyakit hipertensi dan Diabetes Mellitus Tipe-2. Pada pasien DM, fungsi ginjal mengalami penurunan yang menyebakan kadar ureum dan kreatinin meningkat. Selain itu peningkatan kadar kreatinin juga disebabkan oleh usia dan jenis kelamin. Penelitian ini bertujuan untuk mengetahui perbandingan kadar ureum dan kreatinin pasien proalnis lansia DM Tipe-2 berdasarkan jenis kelamin di UPTD Puskesmas banjarmangu 1. Jenis penelitian ini berupa penelitian analitik observasional dengan pendekatan cross sectional menggunakan tekhnik total sampling terhadap pasien prolanis DM Tipe-2 di UPTD Puskesmas Banjarmangu 1. Jumlah sampel sebanyak 21 sampel. Pelaksanaan penelitian dilaksanakan pada bulan Mei 2022, Dan diperoleh hasil nilai p=0,334 (p>0,05) pada nilai ureum dengan jenis kelamin laki-laki, p=0,385 (p>0,05) pada nilai ureum dengan jenis kelamin perempuan, p= 0,177 (p>0,05) pada nilai kreatinin dengan jenis kelamin laki-laki, p=0,168 (p>0,05) pada nilai kreatinin dengan jenis kelamin perempuan. Maka dapat disimpulkan tidak terdapat perbandingan yang signifikan antara kadar ureum dan kreatinin pada pasien prolanis lansia DM Tipe-2 berdasarkan jenis kelamin di UPTD Puskesmas Banjarmangu 1.
Hubungan Umur dan Lingkar Pinggang Dengan Kadar Trigliserida pada Peserta Prolanis di Puskesmas Sumbang I Wahyu Dwi Asriani; Umi Solikhah; Supriyadi Supriyadi; Retno Sulistiyowati
ULIL ALBAB : Jurnal Ilmiah Multidisiplin Vol. 1 No. 10: September 2022
Publisher : CV. Ulil Albab Corp

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Abstract

A decline in physical functional health and the tendency of morbidity increase in the elderly. One of which is coronary heart disease and one of the risk factors is hypercholesterolemia. Waist size is strongly correlated with central obesity and cardiovascular risk. In this case, cardiovascular disease ranks as the first cause of death in Indonesia. It is a general term that describes diseases of the heart or blood vessels. Excess levels of triglycerides in the body are called hypertriglyceridemia. The study was conducted in April-May 2022 by doing descriptive observation. There were only respondents out of 87 were analyzed using univariate and then by correlation test with the result that there is no relationship between age and triglyceride levels with Sig value. F Change (P) of 0.235, which means the value is > 0.05. In the results between waist circumference and triglyceride levels, the results of Sig. F Change (P) of 0.002 which means the value is <0.05 so it can be concluded that waist circumference with triglyceride levels has a relationship and has a strong relationship level at the R value (Correlation Coefficient) of 0.617 has a strong relationshi.
Perbedaan Jumlah Trombosit Menggunakan Antikoagulan K3EDTA dengan Volume Sampel Berbeda pada Karyawan Puskesmas Wanadadi 1 Kab. Banjarnegara Wahyu Hidayah; Tantri Analisawati Sudarsono; Linda Wijayanti; Retno Sulistiyowati
ULIL ALBAB : Jurnal Ilmiah Multidisiplin Vol. 1 No. 10: September 2022
Publisher : CV. Ulil Albab Corp

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Abstract

Platelets (thrombocytes) form a mechanical blockage to the hemostatic response to burns through several reactions, adhesion, aggregation, release, fusion, and procoagulant activity. EDTA prevents platelets from clumping, so it is used as an anticoagulant in the platelet count. Excess concentration of K3EDTA causes shrinkage of blood cells. This study aimed to determine the difference in the number of platelets using K3EDTA anticoagulant with different sample volumes at the Wanadadi 1 Health Center employees, Kab. Banjarnegara. The study was conducted by analytical observation from February August 2022. A total of 10 respondents took 5 ml of blood samples and then divided them into K3EDTA vacutubes with sample volume of 0.5 ml, 1.5 ml, and 2.5 ml. Sample examination using the Hematology Analyzer impedanceelektrik method. The type of research design is analytic observational with a cross-sectional design. Random sampling technique. Data analysis was carried out by conducting a normality test. If the data were normally distributed, p 0.05, then the One Way ANOVA parametric test was continued. The mean number of platelets in a sample volume of 0.5 ml is 287,1000 31,14643 mm, the average number of platelets in a sample volume of 1.5 ml is 294,6000 34.67692 mm, and the average number of platelets in a sample volume of 2.5 ml of 291.1000 35.41955 mm. The lowest mean platelet count was at a volume of 0.5 ml based on statistical tests p = 0.885 (P 0.005). So, there is no significant difference in the number of platelets using K3EDTA Anticoagulants with different sample volumes for employees of Wanadadi Health Care Center 1 Banjarnegara.
Correlation Between Lead Levels and Percentage of Basophilic Stippling in the Blood of Silver Men Ratu Azzahra; Kurnia Ritma Dhanti; Asmiyenti Djaliasrin Djalil; Retno Sulistiyowati
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6818

Abstract

The phenomenon of silver men has become increasingly prevalent in recent years. The direct application of metallic paint to the body and the nature of their activities are major factors contributing to potential lead expsure. Elevated blood lead levels can disrupt hematopoiesis, leading to various blood abnormalities, including the presence of basophilic stippling. Basophilic stippling is a distinctive marker indicative of heavy metal toxicity, particularly lead poisoning. This study aims to examine the correlation between blood lead levels and the presence of basophilic stippling in the blood of silver men in Purbalingga Regency and Purwokerto Sub-district. This study employed an observational analytical design with a cross-sectional approach. The research sample consisted of blood specimens from 14 silver men, selected using accidental sampling. Blood samples (3 mL) were collected from the respondents arms into EDTA tubes. Blood lead levels were analyzed using Atomic Absorption Spectrophotometry (AAS), while basophilic stippling was examined through Giemsa-stained blood smears observed under a microscope. The collected data were analyzed using Pearsons correlation test. The Pearson correlation test yielded a p-value of 0.045 (p 0.05) and a correlation coefficient of 0.542, indicating a strong positive correlation. There is a strong correlation between blood lead levels andthe presence of basophilic stippling in silver men. An increase in blood lead levels is accompanied by the occurrence of basophilic stippling, highlighting the potential toxic effects of lead exposure in this population.
Hubungan Kadar Trigliserida pada Wanita Usia Lebih Dari 45 Tahun dengan Pemberian Susu Tempe Selama 7 Hari Berturut-turut Aisyah Aisyah; Retno Sulistiyowati; Asmiyenti Djaliasrin Djalil; Uli Mas&#039;uliyah Indrawati
MAHESA : Malahayati Health Student Journal Vol 6, No 4 (2026): Volume 6 Nomor 4 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i4.21873

Abstract

ABSTRACT Women Women over the age of 45 often experience pre-menopausal physiological changes, including alterations in lipid metabolism. One consequence is an increased risk of hypertriglyceridemia, which is associated with cardiovascular disease, atherosclerosis, pancreatitis, and metabolic syndrome. Identifying dietary interventions that can help manage lipid levels is essential in promoting long-term health in this population. This study aimed to evaluate the effect of daily tempeh milk consumption for seven consecutive days on triglyceride levels in women aged over 45 years. A total of 25 women aged above 45 years from Ledug Village, Kembaran District, Banyumas Regency, participated in this pre-experimental study. Triglyceride levels were measured before and after the 7-day intervention using photometric analysis at the UMP Clinical Laboratory. Statistical analysis was conducted using the Wilcoxon signed-rank test to assess the significance of changes in triglyceride levels. The findings revealed a statistically significant reduction in triglyceride levels following tempeh milk consumption (p = 0.011). The mean decrease observed was 3.92 mg/dL. Keywords: Triglycerides, Tempeh, Pre-menopause.  ABSTRAK Wanita berusia lebih dari 45 tahun biasanya sudah memasuki masa pre-menopause yang menyebabkan perubahan metabolisme lemak dalam tubuh. Peningkatan kadar trigliserida melebihi normal (hipertrigliseridemia) dapat menyebabkan masalah kesehatan diantaranya peningkatan risiko kardiovaskular, arterosklerosis, pankreatitis dan sindrom metabolik. Tujuan penelitian ini dilakukan untuk mengetahui hubungan kadar trigliserida pada wanita berusia lebih dari 45 (empat puluh lima) tahun dengan pemberian susu tempe selama 7 (tujuh) hari berturut-turut. Sampel pada penelitian ini berupa wanita yang telah memasuki usia lebih dari 45 tahun di Kelurahan Ledug, Kecamatan Kembaran, Kabupaten Banyumas berjumlah 25 orang. Pengukuran kadar trigliserida dilakukan sebelum dan setelah konsumsi susu tempe selama 7 hari bertutut-turut menggunakan metode pemeriksaan fotometer di laboratorium Klinik Pratama Rawat Jalan UMP. Data dianalisis menggunakan uji analisis Wilcoxon dengan hasil nilai P = 0,011. Hasil menunjukan susu tempe berpengaruh secara signifikan dalam penurunan kadar trigliserida yang ditunjukkan dengan nilai P 0,05 dan rata-rata penurunan kadar trigliserida sebanyak 3,92 mg/dL. Kata Kunci: Trigliserida, Tempe, Pre-menopause.
Hubungan Antara Kadar Procalcitonin dengan Jumlah Leukosit pada Penderita Diabetes Melitus Pasca Terapi Bekam Basah: The Correlation between Procalcitonin Levels And Leukocyte Counts In Patients with Diabetes Mellitus After Wet Cupping Therapy ANNISA SHOFIA FAJRO; DITA PRATIWI KUSUMA WARDANI; ULI MASULIYAH INDARWATI; RETNO SULISTIYOWATI; KURNIA RITMA DHANTI
Jurnal Surya Medika (JSM) Vol. 12 No. 1 (2026): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v12i1.12484

Abstract

Diabetes melitus merupakan gangguan metabolik kompleks yang ditandai hiperglikemia dan melibatkan disfungsi multiorgan, termasuk sel β pankreas, jaringan adiposa, otot rangka, dan hati. Penderita diabetes melitus diketahui memiliki risiko infeksi yang lebih tinggi daripada pasien non-diabetes akibat gangguan sistem imun dan kondisi inflamasi kronis. Procalcitonin merupakan biomerker yang meningkat pada infeksi bakteri/sepsis dan digunakan sebagai indikator inflamasi sistemik, sementara leukosit mencerminkan respon imun seluler terhadap proses inflamasi dan infeksi. Kedua parameter ini dapat memberikan gambaran kondisi inflamasi pada penderita DM. Selain itu terapi komplementer seperti bekam basah telah digunakan lama dan diyakini memiliki efek terhadap perbaikan sirkulasi darah dan respon imun. Tujuan penelitian ini untuk mengetahui hubungan antara kadar procalcitonin dengan jumlah leukosit pada penderita diabetes melitus pasca terapi bekam basah. Penelitian ini berjenis quasi-experimental dengan rancangan one group posttest only design yang melibatkan 22 orang penderita DM tipe 2 yang menjalani terapi bekam basah. Data kadar procalcitonin dan jumlah leukosit dianalisis dengan uji korelasi Spearman’s rho. Hasil uji korelasi Spearman’s rho menunjukkan nilai p = 0.635 dan nilai r = 0.107. Tidak terdapat hubungan kadar procalcitonin dengan jumlah leukosit pada pasien DM tipe 2 pasca terapi bekam basah.
The Correlation between Blood Lead (Pb) Levels and Total Leukocyte Count among Silver Man Individuals Fauziah Rahmah; Kurnia Ritma Dhanti; Retno Sulistiyowati; Dina Ratna Juwita
Indonesian Journal of Global Health Research Vol. 8 No. 4 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i4.1674

Abstract

Lead (Pb) exposure remains an environmental health problem that affects groups with direct exposure, including silver man individuals who coat their bodies with paint. Lead is still found in various paint products due to its use as a pigment and additive, making it a potential major source of environmental lead exposure. Lead is known to affect the immune system through inflammatory mechanisms and oxidative stress, which may result in alterations in total leukocyte count. This study aimed to determine the association between blood lead (Pb) levels and total leukocyte count among silver man individuals. This study employed an analytic observational design with a cross-sectional approach involving 18 silver man individuals who were recruited using an accidental sampling technique among individuals who met the inclusion criteria. Blood Pb levels were measured using Atomic Absorption Spectrophotometry (AAS), while total leukocyte counts were analyzed using a hematology analyzer. The relationship between blood Pb levels and total leukocyte count was assessed using Pearsons correlation test. The results showed that all subjects had elevated blood Pb levels. Statistical analysis indicated no significant association between blood Pb levels and total leukocyte count, with a p-value of 0.420 (p 0.05) and a correlation coefficient (r) of 0.202, indicating a positive but very weak correlation. There was no significant association between blood lead (Pb) levels and total leukocyte count among silver man individuals. These findings highlight the importance of vigilance regarding lead exposure and the need for regular health monitoring among at-risk populations.  
The Correlation Between Frequency of Mineral Water Consumption, Coffee, Length of Employment with Serum Creatinine Levels and Estimated Glomerular Filtration Rate among Brick Craftsmen Tuflayfah Khasanah; Defi Nurul Hayati; Retno Sulistiyowati; Kurnia Ritma Dhanti; Minto Rahaju
Indonesian Journal of Global Health Research Vol. 8 No. 4 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i4.2100

Abstract

Chronic Kidney Disease (CKD) leads to a decline in renal function, thereby affecting fluid and electrolyte balance in the body. Risk factors for CKD include advanced age, chronic diseases, kidney disorders, unhealthy lifestyles, and adverse environmental conditions. Prolonged exposure to extreme heat, combined with unhealthy lifestyle behaviors such as inadequate water intake and frequent consumption of caffeinated beverages, may lead to dehydration. Prolonged dehydration can reduce extracellular fluid volume, leading to impaired kidney function. This study aimed to analyze the correlations between the frequency of coffee consumption, water intake, and length of employment with serum creatinine levels and estimated glomerular filtration rate (eGFR) among brick craftsmen in Sokaraja Sub-District, Banyumas. The study employed a cross-sectional design involving 23 respondents selected using accidental sampling. Data analysis was conducted using Spearman and Pearson correlation tests at the 95% confidence level, and a multivariate analysis was performed with multiple linear regression. The bivariate analysis showed significant correlations between coffee consumption, water intake, and work duration and serum creatinine levels and eGFR values (p < 0.05). However, age and length of employment were not statistically significantly associated in the bivariate analysis (p > 0.05). Multivariate analysis indicated that water intake had a significant effect on serum creatinine and eGFR, although this effect was influenced by respondents' age. An increase in coffee consumption was associated with elevated creatinine levels and reduced estimated glomerular filtration rate (eGFR). Inadequate water intake results in dehydration, thereby impairing renal function in the elimination of metabolic waste. Prolonged working hours in hot environments increase the risk of oxidative stress and renal tubule injury.
Korelasi nilai rasio neutofil-limfosit dengan kadar ureum dan kreatinin pada pasien hemodialisa rutin di RSU Wiradadi Husada Kintan Yaumi Lailatil Qodri; Retno Sulistiyowati; Umi Solikhah; Kurnia Ritma Dhanti
JOURNAL OF Community Health Issues Vol. 3 No. 3 (2026): August Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Ikatan Perawat Kesehatan Komunitas Indonesia (IPKKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/chi.v3i3.4088

Abstract

Background: Chronic kidney disease is characterized by a progressive and irreversible decline in kidney function, which may require hemodialysis therapy at an advanced stage. Patients undergoing routine hemodialysis are at risk of chronic inflammation, which can be reflected by the Neutrophil-to-Lymphocyte Ratio (NLR), while urea and creatinine levels can indicate the accumulation of metabolic waste products in the body. Purpose: To determine the correlation between NLR and urea and creatinine levels in patients undergoing routine hemodialysis at RSU Wiradadi Husada. Method: This study used an analytical observational design with a cross-sectional approach and consecutive sampling technique. A total of 42 patients undergoing routine hemodialysis were examined in June 2026. NLR values were obtained from complete blood count results, while urea and creatinine levels were obtained from serum examinations. Data were analyzed using the Spearman correlation test. Results: The results showed no significant correlation between NLR and urea levels (r = 0.054; p = 0.736) or between NLR and creatinine levels (r = −0.189; p = 0.230). Conclusion: There was no significant correlation between NLR and urea or creatinine levels in patients undergoing routine hemodialysis at RSU Wiradadi Husada.
Co-Authors Agny Kusumaningrum Aisyah Aisyah Alfi Noviyana ANNISA SHOFIA FAJRO Arum Wulandari Asmiyenti Djaliasrin Djalil Budi Setyawan Budiarti Budiarti Defi Nurul Hayati Dhanti, Kurnia Ritma Dina Ratna Juwita Dita Pratiwi Kusuma Wardani Etlidawati Falih Aziz Nurzhorif Fauziah Rahmah Iswarno Kintan Yaumi Lailatil Qodri Kurnia Ritma Dhanti Kurnia Ritma Dhanti Kurniawan Kurniawan Lilis Septiana Dewi Linda Wijayanti Minto Rahaju Minto Rahaju Minto Rahaju Minto Rahaju Muallima Tulummah Neneng Siti Nurngaisah Noviani Nur Hayati Nur Rizki Aprilia Utami Nurul Qomariyah Oden Krisyan Ratu Azzahra Sovi Haswindha Putri Nugraheni Sri Yuliati Supriyadi Supriyadi Syifa Arrachmah Tantri Analisawati Tantri Analisawati Sudarsono Tantri Analisawati Sudarsono Tuflayfah Khasanah Uli Mas&#039;uliyah Indrawati Uli Masuliyah Indarwati UMI SOLIKHAH Wahyu Dwi Asriani Wahyu Hidayah Wiwit Rahmawati