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All Journal MKGK (Majalah Kedokteran Gigi Klinik) (Clinical Dental Journal) UGM ODONTO Dental Journal Dentino: Jurnal Kedokteran Gigi Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran E-Prodenta Journal of Dentistry Journal of Case Reports in Dental Medicine Interdental Jurnal Kedokteran Gigi (IJKG) Indonesian Journal of Dental Medicine Sinnun Maxillofacial Journal Odonto dental journal
Desiana Radithia, Desiana
Department Of Oral Medicine, Faculty Of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Knowledge of xerostomia in the elderly in Rejosari Village, Lamongan Regency, East Java Sukmawati, Natasya Fauzia; Ratna Fitri, Adinda; Radithia, Desiana; Parmadiati, Adiastuti Endah; Ayuningtyas, Nurina Febriyanti; Mahdani, Fatma Yasmin
Indonesian Journal of Dental Medicine Vol. 8 No. 1 (2025): Indonesian Journal of Dental Medicine
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v8i1.2025.19-24

Abstract

Background: Xerostomia, or dry mouth, is a subjective sensation often linked to hyposalivation, affecting oral and overall health. With a global prevalence of 5.5% to 46%, it is more common in the elderly due to factors like polypharmacy, systemic diseases, and age-related salivary gland changes. Xerostomia impacts daily activities such as speaking, chewing, and swallowing, reducing quality of life. Rejosari Village in Lamongan Regency, East Java, has a high elderly population and a well-established healthcare center for seniors (Posyandu Lansia), making it an ideal setting for studying awareness and knowledge of xerostomia. Purpose: To describe the level of knowledge of xerostomia among elderly people in Rejosari Village, Lamongan Regency, East Java. Methods: This descriptive observational study utilized an online questionnaire distributed via Google Forms. Participants were selected through consecutive sampling, focusing on elderly individuals who met the inclusion criteria. Of the 75 respondents who completed the questionnaire, 70 were included in the final analysis. Data were analyzed descriptively, categorizing knowledge levels into high, moderate, and low. Results: Among the 70 eligible respondents, 70.00% exhibited a high level of knowledge about xerostomia. Meanwhile, 22.86% were classified as having moderate knowledge, and 7.14% had low knowledge levels. These findings indicate that most elderly residents in Rejosari Village are well-informed about xerostomia, although knowledge gaps persist among certain groups. Conclusion: The elderly’s knowledge about xerostomia in Rejosari Village, Lamongan Regency, East Java is dominated in the high knowledge category.
Presence of Klebsiella Pneumoniae on Black Hairy Tongue as Oral Microbiome Dysbiosis Bakti, Reiska Kumala; Pradnyani , I Gusti Agung Sri; Subarnbhesaj, Ajiravudh; Radithia, Desiana
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 2 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i2.12176

Abstract

Introduction: Black hairy tongue (BHT) is a benign condition characterized by discoloration and elongation of filiform papillae. Although asymptomatic, it can trap microorganisms, potentially contributing to oral dysbiosis. The pathogenesis is still unclear, but smoking, drugs, alcohol, or excessive coffee/tea consumption trigger it. Diagnosis relies on history-taking, clinical assessment, and occasionally microscopic evaluation. This case report aims to show an interesting finding in the microbiological examination of black hairy tongue. Case: A 33-year-old male smoker and coffee drinker presented with black tongue discoloration. Any medication use and a history of systemic diseases are denied, but he had a habit of smoking, staying up late, and heavy coffee consumption. Case Management: Clinical assessment and microbiological swab analysis for bacterial and fungal identification were conducted. Microbiological examination revealed the presence of Klebsiella pneumoniae, a colonizing opportunistic pathogen. Discussion: The patient reported no systemic diseases or medication use, with lifestyle factors identified as potential triggers. This case underscores the role of lifestyle factors and oral hygiene in the development of BHT and its association with microbial dysbiosis. Conclusion: The detection of K. pneumoniae emphasizes the need for microbial evaluation in persistent cases to prevent potential systemic effects.
Effect of freeze-dried platelet-rich plasma on FGF-2 and type I collagen expression in traumatic ulcers of diabetes mellitus: An in vivo study Riskayanti, Ni Putu; Radithia, Desiana; Maharani, Annissaqiella; Hendarti, Hening Tuti; Rahayu, Retno Pudji; Surboyo, Meircurius Dwi Condro; Ernawati, Diah Savitri
Dental Journal (Majalah Kedokteran Gigi) Vol. 58 No. 4 (2025): December
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v58.i4.p361-366

Abstract

Background: Diabetes mellitus is a chronic disease characterized by the pancreas’s inadequate production of insulin or the body’s impaired utilization of insulin, resulting in dysregulation of blood sugar levels. Diabetes mellitus causes prolonged wound healing due to decreased growth factors, including fibroblast growth factor 2 (FGF-2) and type I collagen. Purpose: This research analyzes the effect of topical administration of freeze-dried platelet-rich plasma (FD-PRP) on the healing process of traumatic ulcers in diabetic Wistar rats by increasing FGF-2 and type I collagen expression. Methods: Allogenic FD-PRP was obtained from the blood of 35 Wistar rats and 2% carboxymethyl cellulose (CMC) was added to make a gel formulation. Diabetes was induced in 30 Wistar rats using streptozotocin, followed by the creation of traumatic ulcers on the lower labial mucosa using a hot burnisher. The traumatic ulcers were then topically treated with FD-PRP gel in the treatment group and 2% CMC gel in the control group. Analysis of FGF-2 and type I collagen expression was performed through indirect immunohistochemical methods following treatment for 3, 5, and 7 days. Results: The expression of FGF-2 and type I collagen in the FD-PRP was higher than in the control group (p < 0.05). Conclusion: Topical application of FD-PRP plays an important role, especially in increasing the FGF-2 and type 1 collagen expression, in the healing process of traumatic ulcers in diabetic Wistar rats.
Korelasi antara profil darah lengkap dengan waktu penyembuhan Recurrent Aphthous Stomatitis: observasional analitik Rajah, Karthiyayinee Alagir; Ayuningtyas, Nurina Febriyanti; Parmadiati, Adiastuti Endah; Radithia, Desiana; Mahdani, Fatma Yasmin; Pratiwi, Aulya Setyo; Bakti, Reiska Kumala; Dewi, Gremita Kusuma
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 37, No 2 (2025): Agustus 2025
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v37i2.61016

Abstract

Pendahuluan: Recurrent Aphthous Stomatitis (RAS) merupakan salah satu penyakit pada mukosa rongga mulut yang paling sering dijumpai. RAS timbul dengan berbagai faktor predisposisi, disertai rasa nyeri, dengan waktu penyembuhan yang berbeda-beda. Tes darah lengkap adalah tes darah mengukur beberapa komponen darah termasuk sel darah merah, sel darah putih, hemoglobin, hematokrit dan trombosit. Di antara faktor etiologi RAS diketahui faktor inflamasi yang berperan. Secara teori, diketahui bahwa neutrofil dan limfosit bertanggung jawab terhadap terjadinya inflamasi. Penelitian ini bertujuan untuk menganalisis apakah terdapat korelasi antara profil hitung darah lengkap dan waktu penyembuhan RAS. Metode: Penelitian ini adalah penelitian analitik observasional dengan rancangan potong-lintang (cross-sectional). Metode pengambilan sampel dalam penelitian ini adalah total sampling. Penelitian ini menggunakan 20 pasien yang sedang mengalami RAS. Data pasien didapatkan dari rekam medik RSGM Universitas Airlangga. Data yang diambil lengkap dengan tes darah pasien serta waktu penyembuhan RAS. Data dari kedua variabel dianalisis menggunakan uji korelasi statistik. Korelasi Pearson digunakan ketika data terdistribusi secara normal sedangkan Spearman's Rho digunakan ketika data tidak terdistribusi secara normal. Hasil: Hasil uji korelasi Pearson antara limfosit dan waktu penyembuhan RAS dengan nilai r=-0,459 ; p=0,042 menunjukkan nilai korelasi negatif yang berarti semakin tinggi kadar limfosit maka semakin rendah waktu penyembuhan RAS. Limfosit, trombosit, eosinofil dan LED juga menunjukkan nilai korelasi negatif tetapi tidak signifikan karena p>0,05. Tidak ada nilai signifikan yang ditemukan pada variabel lain kecuali limfosit dan MCHC. Simpulan: terdapat korelasi antara profil darah lengkap (limfosit dan MCHC) dengan waktu penyembuhan RAS.The correlation between complete blood profile and healing time of Recurrent Aphthous Stomatitis: analytical observationalIntroduction: Recurrent Aphthous Stomatitis (RAS) is one of the most common oral mucosa diseases. RAS occurs with various predisposing factors, accompanied by pain, and has varying healing times. A complete blood count is a blood test that measures several blood components, including red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. Among the etiological factors of RAS, inflammatory factors are known to play a role. In theory, it is known that neutrophils and lymphocytes are responsible for inflammation. Methods: This study is an observational analytical study with a cross-sectional design. The sampling method in this study is total sampling. This study used 20 patients who were experiencing RAS. Patient data has been obtained from the medical records of RSGM Universitas Airlangga. The data is complete, including patient blood tests and RAS healing time. Data from both variables were analyzed using statistical correlation tests. Pearson correlation is used when the data is normally distributed, while Spearman's Rho is used when the data is not normally distributed. Results: The results of the Pearson correlation test between lymphocytes and RAS healing time with a value of r = -0,459; p = 0,042 showed a negative correlation value, meaning that the higher the lymphocyte levels, the lower the RAS healing time. Lymphocytes, platelets, eosinophils, and LED also showed negative correlation values but were not significant because p>0,05. No significant values were found in other variables except lymphocytes and MCHC. Conclusion: a correlation exists between complete blood profile (lymphocytes and MCHC) and RAS healing time.
Co-Authors Adiastuti Endah P Adiastuti Endah Parmadiati Adiastuti Parmadiati Asmarawati, Tri Pudy Astrid Marinna Aulya Setyo Pratiwi Ayu Fresno Argadianti Ayuningtyas, Nurina F. Bagus Soebadi Bagus Soebadi Bagus Soebadi Bagus Soebadi Bagus Soebadi, Bagus Bima Ewando Kaban Bima Ewando Kaban Dahlia Riyanto Dewi, Gremita Kusuma Diah Savitri Ernawati Dorisna Prijaryanti Endah, Adiastuti Ernawati, Diah S. Fatma Yasmin Mahdani Hening T. Hendarti Hening Tuti Hendarti Hidayat, Lukman Hakim Intan Noha Brilyanti Iwan Hernawan Kuntardjo, Yuhanna Lani Berlina Talahatu Maharani, Annissaqiella Nafi’ah, Nafi’ah Novitasari Novitasari Nurina Febriyanti Ayuningtyas Pasaribu, Togu Andrie Simon Perwiradinata, Ronden Pradnyani , I Gusti Agung Sri Pramitha, Selviana Rizky Pratiwi, Aulya Setyo Prijaryanti, Dorisna Priyo Hadi Priyo Hadi Priyo Hadi Priyo Hadi, Priyo Puspasari, Karlina Puspitasari, Yeni Rajah, Karthiyayinee Alagir Ratna Fitri, Adinda Reiska Kumala Bakti Retno Pudji Rahayu Rina Kartika Sari Rindang Tanjungsari Riskayanti, Ni Putu Riyanto, Dahlia Rosnah Binti Zain Sismiyanti, Rossy Soebadi, Bagoes Subarnbhesaj, Ajiravudh Sukmawati, Natasya Fauzia Surboyo, Meircurius Dwi Condro Yatty Ravitasari Yuliana Yuliana Yuskhaidir, Yuskhaidir