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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) As-syifaa Jurnal Farmasi Window of Health : Jurnal Kesehatan Jurnal Mandala Pharmacon Indonesia UMI Medical Journal Asy-Syariah ad-Dawaa : Journal of Pharmaceutical Sciences Borneo Journal Of Pharmascientech Jurnal Mandala Pengabdian Masyarakat Jurnal Kajian Ilmu Manajamen Journal of Global Pharma Technology Journal Microbiology Science Jurnal Indonesia : Manajemen Informatika dan Komunikasi Jurnal Pengabdian Masyarakat Journal of Pharmaceuticals and Natural Sciences KOPEMAS MPSJ Jurnal Ilmiah Nusantara Jurnal Balireso: Jurnal Pengabdian pada Masyarakat
Rizqi Nur Azizah
Fakultas Farmasi Universitas Muslim Indonesia
Religion Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Review of Antihypertensive Activity of Purslane (Portulaca oleracea L.) Azizah, Rizqi Nur; Putra, Bayu; Suhaenah, Asriani; Saputri, Fadlina Chany; Ahmad, Aktsar Roskiana; Malik, Abdul
Journal of Pharmaceuticals and Natural Sciences Vol. 2 No. 2 (2025): J. Pharm. Nat. Sci.
Publisher : B-CRETA Publisher (CV. Borneo Citra Kreatama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70392/jpns.v2i2.5461

Abstract

Hypertension is a chronic disease in which blood pressure in the arteries increases. Hypertension is a health problem that has a risk of causing other diseases such as coronary heart disease, kidney failure, nerve dysfunction and stroke. Plants such as purslane (Portulaca oleracea L.) are one of the plants that have benefits in treating disease. The purpose of the review article is to determine the potential of Portulaca oleracea L. as an anti-hypertensive. This research is a Review Journal. The subject of this review is national and international articles indexed nationally and internationally in the last 10 years which discuss the antihypertensive ability of Portulaca oleracea L. by classifying them based on the type of study and test model used in-vivo, the potential of the plant in lowering blood pressure, mechanism of action in treating hypertension, and specific chemical constituents responsible for anti-hypertensive activity. Based on the results of studies conducted on several journal articles, it can be concluded that Portulaca oleracea L. : 1. exhibits promising antihypertensive properties through various mechanisms, including vasodilation, reduction of heart rate, and improvement of endothelial function; 2. Clinical trials and comparative studies indicate that it can significantly reduce systolic blood pressure, making it a potential natural adjunct in managing hypertension; 3. exhibits multiple mechanisms that can help manage hypertension, primarily through its antioxidant, anti-inflammatory, and lipid-regulating properties, 4. contains several bioactive compounds that contribute to its antihypertensive effects such as Asperglaucide (ASP), Oleracein E and Oleracein L, Omega-3 Fatty Acids, Quercetin, and Rutin.
Antiobesity Effect of NADES (Natural Deep Eutectic Solvent) Extract of Purslane Herb (Portulaca oleracea L.) on Male Rats (Rattus norvegicus) Azizah, Rizqi Nur; Santi, Irma; Awali, Muhammad Noer; Putra, Bayu; , Faradiba
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 8 No.1 (2025)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v8i1.56230

Abstract

Introduction: Obesity is a metabolic disorder characterized by excessive fat accumulation, leading to various health complications. One potential approach to managing obesity is through natural products, such as medicinal plants. Aims: This study evaluates the anti-obesity activity of purslane (Portulaca oleracea L.) extract obtained using the green extraction method in male rats (Rattus norvegicus). Method: A total of 18 male rats were divided into six groups: normal control, negative control (Na-CMC + NADES), positive control (orlistat), and three treatment groups receiving NADES Purslane Herb Extract (NPHE) at doses of 50, 100, and 200 mg/kg BW. The treatment groups were induced with a high-fat diet for 30 days, followed by 14 days of therapy. Result: Statistical analysis using One-Way ANOVA and Bonferroni post-hoc test showed that NADES purslane herb extract exhibited significant anti-obesity effects, with the most effective dose being 200 mg/kg BW, which reduced body weight by 13.004% and BMI by 17.935% in male rats. Conclusion: These findings suggest that purslane extract has potential as a natural anti-obesity agent. Further research is needed to explore its bioactive compounds and mechanisms of action, supporting its potential development in pharmaceutical and nutraceutical applications.
Efek Imunomodulator Ekstrak Etanol Herba Krokot (Portulaca oleracea L.) terhadap Tikus Putih (Rattus norvegicus) Jantan dengan Parameter Delayed Type Hypersensitivity (DTH): Effect of Immunomodulator of Purslane Herb Ethanol (Portulaca oleracea L.) on Rat (Rattus norvegicus) with Delayed Type Hypersensitivity (DTH) Parameter Putra, Bayu; Azizah, Rizqi Nur; Nopriyanti, Eka Maryam
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 1 (2020): (March 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (302.679 KB) | DOI: 10.22487/j24428744.2020.v6.i1.14106

Abstract

Portulaca oleracea L. is one of the plants empirically used as medicine and contains flavonoid compounds assumed to have an immunomodulatory effect. The research aimed to determine the immunomodulatory effect of ethanol extract of Portulaca oleracea L by Delayed Type Hypersensitivity parameter. The research used 20 male rats (Rattus norvegicus) divided into 5 groups where each group consisted of 4. Group I as a normal group (without treatment), group II (NaCMC control), group III, IV and V (treatment groups) were given EEHK with doses of 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW doses. The dosage form was orally given for 7 days. On day 3, the rats were induced with SDMD antigen 10% v/v by intraperitonial and intraplantar on day 7. The observations were conducted by measuring the volume change of the rat's feet at the 4th, 24th, and 48th hours using a pletismometer. The research data obtained were statistically processed using Paired Samples T Test, One-Way Anova and Post Hoc LSD tests. The results of the research showed that the ethanol extract of common purslane was effective as an immunomodulator.
Pengaruh Pemberian Ekstrak Etanol Herba Krokot (Portulaca oleracea L.) Terhadap Penurunan Tekanan Sistolik Diastolik Pada Tikus Putih (Rattus norvegicus) Model Hipertensi Putra, Bayu; Azizah, Rizqi Nur; Kosman, Rachmat; Iskandar , A. Nasyrah
BORNEO JOURNAL OF PHARMASCIENTECH Vol 9 No 2 (2025): Borneo Journal Of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59053/bjp.v9i2.642

Abstract

Hypertension is a major risk factor for cardiovascular diseases and can lead to serious complications if not managed optimally. This study aims to evaluate the effects and optimal dose of ethanol extract of purslane herb (Portulaca oleracea L.) in reducing systolic and diastolic blood pressure in hypertensive male rats. The rats were divided into several groups: a negative control, a positive control (captopril), and three treatment groups receiving ethanol extract of purslane at doses of 100, 200, and 300 mg/kg body weight. Systolic and diastolic blood pressure were measured throughout the study to assess the antihypertensive activity of the extract. The results showed that purslane extract at doses of 100, 200, and 300 mg/kg body weight significantly lowered blood pressure, likely due to bioactive compounds such as flavonoids, saponins, and phenols. These compounds exhibit vasodilatory activity, ACE enzyme inhibition, and diuretic effects that contribute to blood pressure reduction in the hypertensive rat model. Ethanol extract of purslane herb (Portulaca oleracea L.) was found to have a significant effect in reducing systolic and diastolic blood pressure in hypertensive rats, with the optimal dose for significant blood pressure reduction being 300 mg/kg body weight
Pengaruh Suplementasi Teh Krokot (Portulaca oleraceae L.) Terhadap Penurunan Kadar Sitokin Tikus Rheumatoid Artritis Azizah, Rizqi Nur; Kamri, Andi Maulana; Asmaliani, Ira; Karisa, Astuti
Jurnal Mandala Pharmacon Indonesia Vol. 10 No. 1 (2024): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v10i1.514

Abstract

Tumor Necrosis Factor Alpha (TNF-?) dan Interleukin-1 (IL-1) merupakan dua sitokini nflamasi utama yang umumnya bekerja secara sinergis untuk memperkuat responi nflamasi. Penelitian ini bertujuan untuk mengetahui pengaruh suplementasi teh Krokot (Portulaca oleracea L.) pada kadar Interleukin-1 (IL-1) tikus dengan Rheumatoida rthritis. Meskipun pada umumnya masyarakat membuat obat tradisional dalamb entuk ramuan herbal, namun kami ingin memberikan pilihan inovasi baru dengan air panas seperti teh. Metode dalam penelitian kami adalah eksperimental dengan melakukan pengukuran kadar sitokin pada serum darah tikus yang dikondisikan mengalami Rheumatoid arthritis menggunakan metode CIA. Rheumatoid faktor dalam serum pasien biasanya ditemukan melalui ekspresi dua sitokin, yaitu TNF-? dan IL-1. Data menunjukkan bahwa pemberian infus teh Krokot 7,5g/L dalam menurunkan kadar TNF-? sebesar 41,0% dan IL-1 sebesar 58,9% serta tidak berbeda nyata dengan Methylprednisolone. Kondisi autoimun yang dikenal sebagai Rheumatoid arthritis ditandai dengan peradangan sendi terus-menerus yang dapat membahayakan jaringan sendi. Hal ini terlihat dari peningkatan IL-1 dan TNF-? yang terjadi setelah perlakuan CIA. Pemberian tek krokot menunjukkan adanya penurunan mendekati Methylprednisolon. Hasil penelitian menunjukkan teh Krokot mampu menurunkank adar TNF-? dan IL-1 pada tikus Rheumatoid arthritis dibandingkan dengan kelompok kontrol.
Profil Pengkajian Resep Racikan Pediatri Pasien Rawat Jalan di Rumah Sakit Umum Daerah Labuang Baji Periode Bulan Juni-Desember 2022 Annisyah, Nur; Ririn, Ririn; Azizah, Rizqi Nur
Makassar Pharmaceutical Science Journal (MPSJ) Vol 1 No 2 (2023)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v1i2.68

Abstract

Prescription screening is one of the pharmaceutical services used to minimize the occurrence of errors in drug prescribing. The purpose of this study was to review the prescription of pediatric concoctions for outpatients in June-December 2022 at Labuang Baji Hospital based on Permenkes No. 72 of 2016 concerning Pharmaceutical Service Standards in Hospitals. non-experimental descriptive research with data collection was carried out retrospectively. The population in this study was 217 prescription sheets. The results showed the percentage of completeness of administrative aspects, namely patient name 98%, patient age 41%, gender 0%, body weight 25%, height 1%, doctor's name 91%, address and doctor's signature and license number 100%, prescription date 93%, prescription origin unit 95%. The suitability of the pharmaceutical aspects, namely the name of the drug, dosage form, amount of drug, rules and methods of use 100%, dosage strength 0%, no incompatibility, 35% hygroscopic & 65% photolysis. The suitability of clinical aspects, namely the accuracy of the indication and the accuracy of the time of use of 100%, there were no drugs that were duplicated, for the accuracy of the dose there were 9% overdose and 5% underdose. From the results of this study it can be concluded that the prescription at Labuang Baji Hospital has not fully met the suitability of the prescription based on Permenkes RI No. 72 of 2016 concerning Pharmaceutical Service Standards in Hospitals.
Hak dan Kewajiban Suami Istri Perspektif Undang-Undang Nomor 1 Tahun 1974 Tentang Perkawinan dan Hukum Islam Rizqi Nur Azizah; Muhammad Yassir
Asy-Syari’ah : Jurnal Hukum Islam Vol. 10 No. 1 (2024): Asy-Syari'ah: Jurnal Hukum Islam, Januari 2024
Publisher : LP3M Universitas Islam Zainul Hasan Genggong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55210/assyariah.v10i1.1409

Abstract

Abstract Right and obligations are two things that cannot be separated, the husband’s rights are obligations that must be fulfilled by the wife and the wife’s rights are things that must be cerried out by a husband. Ignorance of obligations by the wife and husband creates an imbalance in the household. The purpose of this research is to find out the rights and obligations of husband and wife, especially from the perspective of law number 1 of 1974 and Islamic law. This research uses a qualitative approach which is a literatue study, using literature with data sources that are relevant to the topic,in the from of law number 1 of 1974 concerning marriage and Islamic law which of course refers to the Al- quran and sunnah as the main data sources, and is assisted by with relevant support with the title, namely bppks and trusted scientific works. The results of this research show that (1) The wife’s rights are divided into material and immaterial rights, material in the form of dowry and living while immaterial is getting justice in the terms of accommodation and good social realitions. (2) Husband’s rights are not realeted to material or material things, among other the husband’s rights are the right to be obeyed and the right to be served. Keyword: Husband’s; Rights; Obligations. Abstrak Hak dan kewajiban merupakan dua hal yang tidak dapat dipisahkan, hak suami merupakan kewajiban yang harus ditunaikan oleh istri dan hak istri merupakan hal-hal yang harus dijalankan seorang suami, ketidaktahuan tentang kewajiban oleh istri maupun suami membuat adanya ketidakseimbangan di dalam rumah tangga. Tujuan dari penelitian ini untuk mengetahui bagaimana hak dan kewajiban suami istri khususnya perspektif undang-undang nomor 1 tahun 1974 dan hukum Islam. Penelitian ini menggunakan jenis pendekatan kualitatif yang bersifat studi literatur, penggunaan literatur dengan sumber data yang relevan dengan topik, berupa undang-undang nomor 1 tahun 1974 tentang perkawinan dan hukum Islam yang tentunya merujuk pada Al-quran dan Sunnah sebagai sumber data utama, dan dibantu dengan penunjang yang relevan dengan judul yaitu buku dan karya ilmiah yang terpercaya. Hasil penelitian ini menunjukkan bahwa (1) Hak istri terbagi menjadi hak materil dan imateril, materil berupa mahar dan nafkah sedangkan imateril adalah mendapatkan keadilan dalam jatah menginap dan dipergauli dengan baik, (2) Hak suami tidak ada yang berkaitan dengan materil atau kebendaan, diantara hak suami adalah hak ditaati dan hak dilayani. Kata Kunci: Suami Istri; Hak; Kewajiban.
PEMBINAAN MASYARAKAT SEBAGAI APLIKASI GERAKAN MASYARAKAT CERDAS MENGGUNAKAN OBAT (GEMA CERMAT) PADA SISWA MTS WIHDATUL ULUM DESA BORISALLO KABUPATEN GOWA. Azizah, Rizqi Nur
Jurnal BALIRESO Vol 5, No 1 (2020)
Publisher : Lembaga Pengabdian kepada Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/balireso.v5i1.135

Abstract

Gerakan Masyarakat Cerdas Menggunakan Obat "GeMa CerMat" is an effort of the governmentand society through a series of activities in realizing community care, awareness, understandingand skills in using drugs correctly and correctly. UMI as an education and da'wah institutionalways supports government programs in the health sector. The target of this service is thestudents of MTs Wihdatul Ulum Desa Borisallo, Parangloe Subdistrict, Gowa Regency, who areable to get to know things related to drugs and can use drugs safely and avoid the effects ofunwanted drugs. In addition, it is expected to be able to inform drug related matters to othercommunities. The method of disseminating service activities to the Wihdatul Ulum Islamicboarding school, counseling on rational use of medicine with lecture and discussion methods, thencontinued with training in rational drug use through Active Learning Method (CBIA) methods,evaluation of service activities, and publication of activities in the media print and online. Fromcounseling activities and rational drug use training conducted to MTs students. Wihdatul UlumDesa Borisallo Kec. Parangloe Gowa Regency, which was attended by 30 participants, obtained anaverage pretest value of 0.3 and an average posttest value of 4.8. The Efforts of the SmartCommunity Movement to Use Medication (GeMa CerMat) for Students of MTs Wihdatul Ulum inBorisallo Village, Gowa Regency effectively increase knowledge related to drugs in selfmedication.
Co-Authors , Faradiba A. Hudayah Abdul Malik Ahmad, Aktsar Roskiana Aisyah Alda, Alda Andi Clara Andi Maulana Kamri Annisyah, Nur Ardiansah Hasin Asriani Suhaenah Asrianto, La Ode Aulia Wati Awali, Muhammad Noer Bayu Putra Bayu Putra, Bayu Chikita Inaku Christiana Lethe Fadlina Chany Saputri Fitriana Fitriana Gemini Alam Hasanuddin, Asni Hendra Herman Irma Santi Irma Santi, Irma Iskandar , A. Nasyrah Iskandar Zulkarnain Karisa, Astuti Karyadi Marlian, Ayu Mirawati Mirawati Mudinillah, Adam Muhammad Irman Muhammad Yassir Mu’ammar Mu’ammar Nirma Kurriwati, Nirma Nopriyanti, Eka Maryam Nurwahida Nurwahida Rachmat Kosman Rachmat Kosman, Rachmat Rafika Tobis Rini Suwartika Kusumadiarti Ririn Ririn SALIM, MUH.AGUS Sukmawati Sukmawati Syarifah Khaerunnisa Ulupalu, Fadila Fauzia Mutmaina Yurniati Yusnita Rifai