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All Journal Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Indonesian Journal of Tropical and Infectious Disease Jurnal Respirologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research
Zarfiardy Aksa Fauzi
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Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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GAMBARAN PERILAKU MEROKOK GURU DI LINGKUNGAN SEKOLAH MENENGAH PERTAMA DI PEKANBARU Sari, Suci Maya; Afandi, Dedi; Fauzi, Zarfiardy Aksa
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTSmoking remains one of the leading problem that can't be resolved until now. One of the important factor is the junior high school as education institutions that produce the next generations that not only excellent in achievment but also care about health of themselves and environment. Teachers as role models in schools also had important role in students attitude and behavior formation. This research aims to determined the smoking behavior among teachers in junior high school in Pekanbaru. This research was a descriptive study with cross-sectional approach. This study had been done on September 2014 with 210 teachers from seven Junior High Schools in Pekanbaru as respondents. Results showed that all respondents (100%) had good knowledge, good attitude as much as 202 respondents (96.2%), and as many as 187 people (89%) had good behavior. Keywords : smoking , knowledge , attitudes and behavior
DESCRIPTION BEHAVIOR DOCTOR AND NURSE ABOUT PREVENTION TRANSMISSION OF TB DISEASE Indah Sahana; Zarfiardy Aksa Fauzi; Fifia Chandra
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 4, No 1 (2017): Wisuda Februari 2017
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTDoctor and nurse have a high risk for contracting TB because often dealing directly with patients. Data in Africa Country (84%) health workers infected TB. Data estimated Malaysia about incidence of TB among health workers has also risen in 2008 (80.59%), 2009 (71.42%) and 2010 (97.86%). Prevention can be done if they have good knowledge, attitude and practice about prevention of TB transmission. The Purpose of this study was to be describe behavior doctor and nurse about prevention transmition TB disease. This research was held in twenty primary health Pekanbaru Citty by using descriptive method with cross sectional approach. Samples in this study were doctor and nurse in primary health Pekanbaru. The samples consisted of 128 respondents. The respondents in this study aged 35-45 years at most that doctors (50.0%) and nurses (51.6%), the majority of which are female doctors (95.8%) and nurses (97.5%), educated bachelor degree doctor (100%) and diploma 3 in nurse (67 %). The results of this study, the levelof knowledge in the category of good, that doctors (97.9%) and nurses (97.5%), while a positive attitude in the category of physician (85.4%) and nurses (82.5%), while the action obtained in the category enough that a doctor (100%) and nurses(100%).Keywords: Knowledge, attitudes, practice, behaviors, prevention of TB transmission
GAMBARAN NILAI SGOT DAN SGPT PASIEN TUBERKULOSIS PARU YANG DIRAWAT INAP DI RSUD ARIFIN ACHMAD PROVINSI RIAU TAHUN 2013 Widya Adriani; Zarfiardy Aksa Fauzi
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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AbstractTuberculosis (TB) adalah suatu penyakit infeksi menular yang disebabkanoleh kuman Mycobacterium tuberculosis.Tuberculosis ( TB ) is an infectious diseasecaused by Mycobacterium tuberculosis. TB germs attack the organ is mostly thelungs ( pulmonary TB ) , but also can affect almost every organ of the human body .Morbidity and mortality from tuberculosis is a serious problem , especially due to theincidence of side effects due to Anti Tuberculosis ( OAT ) . Side effects The mostserious OAT is hepatotoxic .According to the American Association for the Study of Liver Disease (AASLD ) , establishes that the parameters for determining the presence or absence ofliver damage is to look at the levels of serum glutamic Pyruric transaminase ( SGPT )increased more than three times the upper limit of normal , and serum glutamicoxaloacetic transaminase ( SGOT ) . The purpose of this study to describe the valueof AST and ALT in patients with pulmonary tuberculosis hospitalized in ArifinAchmad Riau Province in 2014 by age , sex and determine the degree ofhepatotoxicity . This study will be conducted at the medical records of the DistrictGeneral Hospital Arifin Achmad Riau Province in January 2015 .The study sample as many as 69 people . The data collected is secondarydata obtained from medical records . The results showed that the largest age groupof patients with pulmonary tuberculosis were aged 40-49 years were 17 ( 24.63 % ) .While the sex of pulmonary TB patients it was found that men were 36 people ( 52.17% ) . Pulmonary TB patients who experienced hepatotoksitas based SGOT was 10people ( 14.49 % ) . Pulmonary TB patients with hepatotoxicity based SGPT value is7 ( 10.14 % ) .pulmonary TB patients with hepatotoxicity based AST highest in the agegroup 40-49 years are 4 people and hepatotoxicity based SGPT highest in the agegroup 18-29 years is 3 people . pulmonary TB patients with hepatotoxicity based ASTsame incidence between men and women respectively 5 people . Pulmonary TBpatients with hepatotoxicity based SGPT most suffered by men is 6 people , whilewomen only 1 person .Keywords: Pulmonary tuberculosis , SGOT , SGPT
PERBEDAAN KADAR SGPT PADA PASIEN TUBERKULOSIS PARU SEBELUM DAN SESUDAH FASE INTENSIF DI POLIKLINIK PARU RSUD ARIFIN ACHMAD PEKANBARU Rafika Annisa; Zarfiardy Aksa Fauzi; Fridayenti "
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 2 (2015): Wisuda Oktober 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACTTuberculosis (TB) is still a cause of high morbidity which can mainly due to the onset of side effects from the use of Anti-Tuberculosis Drugs (OAT). One of the most serious side effects are hepatotoxic. Early markers of hepatotoxicity is an increase of enzymes in serum transaminase consisting of glutamate oxaloacetate transaminase (SGOT) which is secreted in parallel with glutamate pyruvate transaminase (SGPT). This study aims to determine differences in SGPT levels before and after intensive phase in patients with pulmonary tuberculosis in the pulmonary polyclinic of Arifin Achmad general hospital Pekanbaru. This research uses descriptive method with cross sectional approach. The sampling technique used is total sampling technique. The study was conducted in February-May 2015 and obtained 32 samples which is a tuberculosis patient at the Pulmonary Polyclinic Arifin Achmad general hospital. Results from this study are characteristic of most patients by age is 18-54 years is 22 (68.8%) of people, sex is a male majority, with result 19 (59.4%) people. SGPT levels of pulmonary tuberculosis patients after intensive phase for 8 weeks found elevated levels of ALT in 1 (3.1%). Based on an analysis using paired sample t test found a significant difference between the levels of ALT before and after the 8-week intensive phase during which p = 0.001 <0.005.Keywords: Pulmonary tuberculosis, SGPT levels.
ANGKA KEJADIAN TUBERKULOSIS PARU PADA PASANGAN SUAMI-ISTRI PNEDERITA TUBERKULOSIS PARU BTA POSITIF DI POLIKLINIK PARU RSUD ARIFIN ACHMAD Diadema Al Arif,; Zarfiardy Aksa Fauzi; Fauzia Andrini
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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AbstractPulmonary tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Mycobacterium tuberculosis is carried in airborne particles, called droplet nuclei. Tuberculosis infection is spread from a person ti person by inhaling the droplets of infected material produced by a person with infectious pulmonary tuberculosis, patients with positive Acid Fast Bacilli (AFB) smear. Droplet nuclei can survive in the air for several hours depend on enviromental factor, source case or person with active tuberculosis and contact or person who is exposed to infectious pulmonary tuberculosis patients. Home is vulnerable place for transmission this disease to its contacts. Family such as spouse, children and parents have a higher risk to be transmitted. This was a descriptive study to know prevalence of pulmonary tuberculosis in spouse of pulmonary tuberculosis patients with positive Acid Fast Bacilli (AFB) smear in Arifin Achmad General Hospital. The samples of this study are 30 people. Results showed that 1 samples (3,33%) had a positive Acid Fast Bacilli (AFB) smear and abnormal radiographKeyword : tuberculosis,transmission,spouse
Profile of Pulmonary Tuberculosis After COVID-19 at Toba District, North Sumatra Province Simatupang, Elvando Tunggul Mauliate; Simanjuntak, Arya Marganda; Yovi, Indra; Simbolon, Rohani Lasmaria; Fauzi, Zarfiardy Aksa
Jurnal Respirologi Indonesia Vol 44, No 4 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i4.716

Abstract

Background: Worldwide cases of pulmonary tuberculosis (PTB) have significantly increased since the COVID-19 pandemic. Indonesia accounted for 6,811,818 of the 767,518,723 cases reported by the World Health Organization. While the Indonesian Ministry of Health reported 824,000 cases, the Global Tuberculosis Report in 2022 reported 10.6 million cases. The pandemic has hampered the goal of eliminating PTB globally, with cases diagnosed after COVID-19 having a 7.15-fold increased risk of contracting the illness.Methods: This cross-sectional study was conducted using total sampling to identify the profile of patients with PTB after having COVID-19 based on age, gender, classification, and type of PTB, as well as the duration of occurrence of PTB after COVID-19. The data collected were from COVID-19 patients from 2020 to 2022, then compared with PTB data. All data were compared to ensure that COVID-19 and PTB patient data were the same.Results: Of the 2544 patients recorded, 29 (1.1%) were infected with PTB after COVID-19 infection. The mean age of patients was 34±18.9 and was dominated by men (68.9%). Most of the cases were drug-sensitive TB (96.6%) and clinically diagnosed TB (55.2%). Age had a statistically significant association with the occurrence of TB cases after COVID-19 infection (P<0.0001). The mean time from the initial diagnosis of COVID-19 to the diagnosis of confirmed TB was approximately 203±34.3 days (6.7 months).Conclusion: After COVID-19, patients have the potential to be infected with TB. Screening former COVID-19 patients can be one solution to finding early cases of PTB.
Atypical Pneumonia in the Elderly: A Meta-Analysis of Risk Factors, Treatment Outcomes, and Mortality Veghasanah Tanlie; Zarfiardy Aksa Fauzi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 3 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i3.1225

Abstract

Background: Atypical pneumonia poses a significant threat to elderly individuals, often leading to severe complications and increased mortality. This meta-analysis aimed to evaluate risk factors, treatment outcomes, and mortality associated with atypical pneumonia in elderly patients. Methods: A systematic search of PubMed, Embase, and Cochrane Library databases was conducted from January 2013 to December 2024. Studies reporting on atypical pneumonia in patients aged 65 years or older were included. Data on risk factors, treatment outcomes (clinical cure rate, radiological improvement, length of hospital stay), and mortality were extracted and pooled using random-effects models. Results: Six studies involving 1,875 elderly patients with atypical pneumonia were included. Advanced age (≥80 years), comorbidities (chronic obstructive pulmonary disease, heart failure, diabetes mellitus), and delayed initiation of antibiotic therapy were identified as significant risk factors for severe disease and mortality. Treatment with macrolides was associated with a higher clinical cure rate (OR 2.15, 95% CI 1.52-3.04, p<0.001) and shorter hospital stay (mean difference -2.8 days, 95% CI -4.1 to -1.5, p<0.001) compared to fluoroquinolones. The pooled mortality rate was 12.8% (95% CI 9.5-16.1%). Conclusion: Atypical pneumonia in the elderly is associated with significant morbidity and mortality. Early recognition of risk factors and prompt initiation of appropriate antibiotic therapy, particularly with macrolides, are crucial for improving outcomes in this vulnerable population.
Update on The Current Management of Drug Resistant Tuberculosis (DR-TB) Simbolon, Rohani Lasmaria; Simatupang, Elvando Tunggul Mauliate; Yovi, Indra; Fauzi, Zarfiardy Aksa
Indonesian Journal of Tropical and Infectious Disease Vol. 13 No. 2 (2025)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v13i2.59075

Abstract

Drug-Resistant tuberculosis (DR-TB) is a global public health threat that requires a comprehensive response from all parties. DR-TB cases are often overlooked and tend to increase every year. Efforts to overcome DR-TB cases began in 2009 with the use of a molecular test, Xpert MTB/Rif, as a diagnostic tool. This has now been developed with the procurement of a molecular test with Xpert MTB/XDR. This diagnostic update also formed the basis of the latest DR-TB classification terminology by not categorizing polyresistance into the DR-TB group. This step is still not in accordance with the low success rate of DR-TB treatment in Indonesia, ranging from 45-50%. The latest DR-TB management recommendations by WHO in 2022 have implemented a 6-month treatment regimen to minimize the occurrence of treatment dropout or patient treatment non-compliance. The BPaLM/BPaL regimen is a shorter-duration oral regimen that is expected to help achieve the End TB 2015-2030 targets. Previously used short-term regimens have now been modified with Ethionamide and Linezolid variants as alternatives for DR-TB management if the BPaLM/BPaL regimen does not meet the criteria for use.
Co-Authors Dedi Afandi Diadema Al Arif, Fauzia Andrini Fifia Chandra Fridayenti " Indah Sahana INDRA YOVI Rafika Annisa Rohani Lasmaria Simbolon, Rohani Lasmaria Simanjuntak, Arya Marganda Simatupang, Elvando Tunggul Mauliate Suci Maya Sari Veghasanah Tanlie Widya Adriani