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All Journal Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Indonesian Journal of Tropical and Infectious Disease Jurnal Respirologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Respiratory Science Bioscientia Medicina : Journal of Biomedicine and Translational Research Malang Respiratory Journal jabdimasunipem
Zarfiardy Aksa Fauzi
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Public Health Other

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Lung Cancer In Former Tuberculosis Patients at Arifin Achmad General Hospital, Riau Province Martarita, Evitrie; Erdayani, Rita; Munir, Sri Melati; Fauzi, Zarfiardy Aksa; Simanjuntak, Arya Marganda
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.97

Abstract

Background: There is ongoing discussion over the connection between lung cancer and pulmonary tuberculosis (TB). Future lung cancer cases in Indonesia, which has the second-highest TB case burden, are a cause for concern. The purpose of this study is to ascertain the connection between TB and LC at Arifin Achmad General Hospital in the province of Riau. Method: From 2015 to 2018, we looked back on lung cancer patients at Arifin Achmad General Hospital in Riau Province who had received pulmonary tuberculosis and anti-tuberculosis treatment (ATT). Results: From 203 patients, 24 patients (11.8%) had histories of TB. The patients' ages were from 41 years to 60 years. The most prevalent pathological findings were adenocarcinoma in 13 patients (54.0%). The most common cancer stage was advanced stage IIIB in 7 patients (29.2%) Conclusion: The cases of TB infections were apparent in lung cancer patients, approximately around 11% of lung cancer cases. Therefore, it is necessary to assess the history of TB in lung cancer patients.
Characteristics of Lung Cancer Patients with Brain Metastases based on Baseline Head Computerized Tomography (CT)-scan in Arifin Achmad Hospital October 2022 - June 2023 Sari, Rezki Permata; Fauzi, Zarfiardy Aksa; Simanjuntak, Arya Marganda
Respiratory Science Vol. 4 No. 2 (2024): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i2.108

Abstract

Background: The majority of lung cancer cases are often discovered at a late stage because it frequently develops without symptoms in the early stages. Many lung cancer deaths are caused by metastases to other organs. The purpose of this study was to examine the features of lung cancer patients with brain metastases using baseline CT scan data. Method: Between October 2022 and June 2023, a cross-sectional study was conducted at the Arifin Achmad Hospital in Pekanbaru on all newly diagnosed lung cancer patients with brain metastases who also met the inclusion and exclusion criteria. Results: Eight subjects of lung cancer with brain metastasis were found from 49 patients. All subjects were male with age mostly in between 40 and 60 years. Three subjects (37.5%) were Squamous Cell Carcinoma (SCC), four subject (50%) were adenocarcinoma and 1 (12.5%) were SCLC. Conclusion: This study discovered that 16.3% of patients who met the inclusion criteria had lung cancer with brain metastases. Further research should be done on a cohort study and a preventive strategy for lung cancer with brain metastases.
Successful Autologous Blood Patch Pleurodesis: A Safe and Useful Treatment for Persistent Pneumothorax in Former Pulmonary Tuberculosis and Aspergillosis in Pregnant Women Purnama, Nori; Simatupang, Elvando Tunggul Mauliate; Fauzi, Zarfiardy Aksa; Indriani, Sri; Yovi, Indra; Hatta, Hariadi; Zulmaeta
Malang Respiratory Journal Vol. 6 No. 1 (2024): March 2024 Edition
Publisher : Universitaas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mrj.2024.006.01.04

Abstract

Background: Autologous Blood Patch Pleurodesis (ABPP) is one of the treatment options for persistent pleural air leaks especially in patients who are not suitable for surgical intervention. Persistence pneumothorax is defined as pneumothorax of more than five days duration. It is associated with increased morbidity and cost of care. The most widely accepted treatment for it is pleurodesis. Several types of pleurodesis have been proposed, including surgical approaches and the instillation of different chemicals in the intrapleural space. ABPP has proven to be a simple, inexpensive, efficacious and safe method. We present the case of the first patient with Persistent Pneumothorax we have treated Successfully with ABPP. ABPP is currently rarely and uncommonly used, but it provides benefits especially in special conditions with easier, cheaper, and quite effective procedures. Case: A female 35-year-old pregnant women patients with Former Tuberculosis (FTB) come to our hospital with complaints breathlessness and chest pain worsening since 3 days before admitted to our hospital. Chest radiography showed spontaneous pneumothorax with GeneXpert (GE) sputum Mtb Not Detected but there is Aspergillosis from Fungal Culture. Water Sealed Drainage (WSD) was inserted in right pleural for almost 1 month and this patient discharge with pneumostat. One month after that she come again with Persistence Pneumothotax, so that we do the pleurodesis with Blood Patch and get the improvement from clinical status. Antifungals are continued for an initial 4-6 weeks while an outpatient evaluation is conducted. Conclusion: ABPP is a safe, inexpensive and efficacious treatment for persistent pleural air leak. Autologous Blood Patch administration may be considered for patients with Persistent Pneumothorax.
EDUKASI DAN SKRINING KESEHATAN PERNAPASAN PADA PENYINTAS COVID-19 DI WILAYAH KERJA PUSKESMAS RUPAT UTARA Kemal, Rahmat Azhari; Pernantah, Piki Setri; Suyanto; Arfianti; Fauzi, Zarfiardy Aksa
Jurnal Abdimas Universitas Insan Pembangunan Indonesia Vol. 2 No. 1 (2024): Abdimas Unipem
Publisher : LPPM Universitas Insan Pembangunan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58217/jabdimasunipem.v2i1.25

Abstract

Pasien Covid-19 dapat memiliki gejala yang berkepanjangan setelah dinyatakan negatif SARS-CoV-2. Kondisi ini disebut sebagai long Covid. Kualitas kesehatan masyarakat penyintas Covid-19 tersebut perlu ditingkatkan. Kecamatan Rupat Utara merupakan salah satu daerah pesisir dan perbatasan di Kabupaten Bengkalis, Provinsi Riau. Lokasi tersebut menyebabkan relatif sulitnya akses ke layanan kesehatan tersier. Oleh karena itu, tujuan dari kegiatan pengabdian kepada masyarakat ini adalah memberikan edukasi dan skrining kesehatan pernapasan pada penyintas Covid-19. Kegiatan pengabdian ini dilaksanakan dengan metode pemberian edukasi berupa pemaparan materi long Covid dan pentingnya vaksinasi Covid-19, pengenalan senam pernapasan, serta pemeriksaan spirometri pada penyintas Covid-19. Hasil dari kegiatan ini adalah meningkatnya pengetahuan warga mengenai long Covid dan vaksinasi Covid-19. Masyarakat juga mengetahui dan dapat mempraktikkan senam pernapasan untuk meningkatkan kesehatan pernapasan. Hasil skrining spirometri menunjukkan peserta memiliki kesehatan pernapasan yang baik. Melalui kegiatan ini, masyarakat terutama penyintas Covid-19 di Rupat Utara dapat memiliki kualitas kesehatan yang baik setelah sembuh dari Covid-19.
The Correlation Between Type and Stage of Lung Cancer with The Chronic Obstructive Pulmonary Disease Group at Arifin Achmad Hospital, Pekanbaru Gurning, Andi Sarikawan; Munir, Sri Melati; Yunus, Faisal; Fauzi, Zarfiardy Aksa; Adrianison, Adrianison; Yovi, Indra; Indriani, Sri Indah
Jurnal Respirologi Indonesia Vol 45 No 2 (2025)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v45i2.512

Abstract

Background: The relationship between lung cancer (LC) and chronic obstructive pulmonary disease (COPD) has been extensively studied but is still up for debate. COPD is a molecularly based illness and one of the independent risk factors for lung cancer, particularly squamous cell carcinoma. This study uses spirometry to assess the relationship between the type and stage of LC and COPD in a group of LC patients at Arifin Achmad Hospital. Methods: This cross-sectional study was conducted on lung cancer patients in Arifin Achmad Hospital, Pekanbaru, from June 2022 to December 2022. Based on spirometry examination, patients were grouped according to the degree of COPD. Then, the relationship between the COPD group and the type and degree of cancer was determined. Results: The study involved 52 patients predominantly male (71.2%), aged over 40 years (92.3%), Smokers and former smokers with Severe Brinkman index (69.2%), restrictive lung function (34.6%), COPD group D (40.4%), adenocarcinoma (61.5%), stage IV lung cancer (92,3%) and WHO Performance Status Scale 2 (61.5%). The FEV1/FVC rate in this study was 66.67%. There is a link between the stage of lung cancer and the group of COPD (P=0.001). Conclusion: There is a relation between the stage of LC in the COPD group, which is predominantly with stage IV lung cancer, and group D of COPD.
Profile of Pulmonary Tuberculosis After COVID-19 at Toba District, North Sumatra Province Simatupang, Elvando Tunggul Mauliate; Simanjuntak, Arya Marganda; Yovi, Indra; Simbolon, Rohani Lasmaria; Fauzi, Zarfiardy Aksa
Jurnal Respirologi Indonesia Vol 44 No 4 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i4.716

Abstract

Background: Worldwide cases of pulmonary tuberculosis (PTB) have significantly increased since the COVID-19 pandemic. Indonesia accounted for 6,811,818 of the 767,518,723 cases reported by the World Health Organization. While the Indonesian Ministry of Health reported 824,000 cases, the Global Tuberculosis Report in 2022 reported 10.6 million cases. The pandemic has hampered the goal of eliminating PTB globally, with cases diagnosed after COVID-19 having a 7.15-fold increased risk of contracting the illness.Methods: This cross-sectional study was conducted using total sampling to identify the profile of patients with PTB after having COVID-19 based on age, gender, classification, and type of PTB, as well as the duration of occurrence of PTB after COVID-19. The data collected were from COVID-19 patients from 2020 to 2022, then compared with PTB data. All data were compared to ensure that COVID-19 and PTB patient data were the same.Results: Of the 2544 patients recorded, 29 (1.1%) were infected with PTB after COVID-19 infection. The mean age of patients was 34±18.9 and was dominated by men (68.9%). Most of the cases were drug-sensitive TB (96.6%) and clinically diagnosed TB (55.2%). Age had a statistically significant association with the occurrence of TB cases after COVID-19 infection (P<0.0001). The mean time from the initial diagnosis of COVID-19 to the diagnosis of confirmed TB was approximately 203±34.3 days (6.7 months).Conclusion: After COVID-19, patients have the potential to be infected with TB. Screening former COVID-19 patients can be one solution to finding early cases of PTB.
Tuberculosis with Drug-Induced Hepatitis: A Narrative Literature Review Sari, Riska Yuliana; Zarfiardy Aksa Fauzi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 2 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i2.929

Abstract

Tuberculosis (TB) is an infectious disease that is a global health problem. The problem is that 5-28% of patients receiving tuberculosis treatment suffer from drug-induced hepatitis on antituberculosis drugs (OAT). The clinical picture should be differentiated from other liver diseases. The level of symptoms varies from asymptomatic to symptomatic, such as nausea, vomiting, abdominal pain, jaundice, hepatomegaly, and increased liver function. OAT use is stopped if clinical symptoms are found and ALT/AST increases ≥3 times, or if there are no symptoms but there is an increase in bilirubin ≥2 mg/dl or ALT/AST values ≥5 times without clinical symptoms. The use of OAT can be continued, but with supervision, if there are no clinical symptoms and the increase in ALT/AST is <2 times and the bilirubin value is <2 mg/dl. Treatment can be carried out again by reintroducing OATs one by one according to ATS recommendations.
The Relationship between COVID-19 Vaccination and the Severity of COVID-19 in Patients Treated for the Period August 2021 – August 2022 at Arifin Achmad General Hospital, Riau Province, Indonesia Ardiansyah, Muhammad Yudhi; Zarfiardy Aksa Fauzi; Rohani Lasmaria S
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 3 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i3.938

Abstract

Background: The use of the COVID-19 vaccine is very effective in controlling the pandemic, but it is important to know that no vaccine is 100% effective in preventing the COVID-19 pandemic. Vaccination can make the disease milder so that the risk of infection, hospitalization, and death is lower in people who have been vaccinated compared to those who have not been vaccinated. This study aims to determine the relationship between COVID-19 vaccination and the severity of COVID-19 infection in patients treated at Arifin Achmad General Hospital, Riau Province, for the period August 2021 to August 2022. Methods: This study is an analytical observational research with a cross-sectional approach. A total of 403 research subjects were included in this study. Data analysis using Chi-square by looking for the relationship between the dependent variable and the independent variable. Ineligible bivariate data will be performed using the Fisher test with a p-value < 0.05 considered significant based on statistical tests. Results: The percentage of mild and moderate severity patients was generally the highest in the group who did not receive vaccination, with the percentage being 45.8%, followed by those who received booster (30.4%). Of the 54 cases of patients with severe-critical severity, 27 cases were dominated by patients who had no vaccination status at all, with a percentage of 50.0%. Subjects who did not receive vaccination had a 3.37 times higher chance of developing severe COVID-19 than those who were vaccinated (odds ratio = 3,37; 95% confidence interval [THERE] = 1,95-4,80). Conclusion: The relationship between COVID-19 vaccination and the severity of COVID-19 infection in patients treated at Arifin Achmad General Hospital, Riau Province, for the period August 2021 to August 2022.
Atypical Pneumonia in the Elderly: A Meta-Analysis of Risk Factors, Treatment Outcomes, and Mortality Veghasanah Tanlie; Zarfiardy Aksa Fauzi
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 3 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i3.1225

Abstract

Background: Atypical pneumonia poses a significant threat to elderly individuals, often leading to severe complications and increased mortality. This meta-analysis aimed to evaluate risk factors, treatment outcomes, and mortality associated with atypical pneumonia in elderly patients. Methods: A systematic search of PubMed, Embase, and Cochrane Library databases was conducted from January 2013 to December 2024. Studies reporting on atypical pneumonia in patients aged 65 years or older were included. Data on risk factors, treatment outcomes (clinical cure rate, radiological improvement, length of hospital stay), and mortality were extracted and pooled using random-effects models. Results: Six studies involving 1,875 elderly patients with atypical pneumonia were included. Advanced age (≥80 years), comorbidities (chronic obstructive pulmonary disease, heart failure, diabetes mellitus), and delayed initiation of antibiotic therapy were identified as significant risk factors for severe disease and mortality. Treatment with macrolides was associated with a higher clinical cure rate (OR 2.15, 95% CI 1.52-3.04, p<0.001) and shorter hospital stay (mean difference -2.8 days, 95% CI -4.1 to -1.5, p<0.001) compared to fluoroquinolones. The pooled mortality rate was 12.8% (95% CI 9.5-16.1%). Conclusion: Atypical pneumonia in the elderly is associated with significant morbidity and mortality. Early recognition of risk factors and prompt initiation of appropriate antibiotic therapy, particularly with macrolides, are crucial for improving outcomes in this vulnerable population.
Co-Authors Adrianison, Adrianison Ardiansyah, Muhammad Yudhi Arfianti Arfianti Dedi Afandi Diadema Al Arif, Erdayani, Rita Faisal Yunus Fauzia Andrini Fifia Chandra Fridayenti " Gurning, Andi Sarikawan Hatta, Hariadi Indah Sahana INDRA YOVI Indriani, Sri Indah Martarita, Evitrie Pernantah, Piki Setri Purnama, Nori Rafika Annisa Rahmat Azhari Kemal Rohani Lasmaria S Rohani Lasmaria Simbolon, Rohani Lasmaria Sari, Rezki Permata Sari, Riska Yuliana Simanjuntak, Arya Marganda Simatupang, Elvando Tunggul Mauliate Sri Indriani Sri Melati Munir Suci Maya Sari Suyanto Veghasanah Tanlie Widya Adriani Zulmaeta