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All Journal Jurnal Kedokteran Brawijaya Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Medical and Health Journal
Miko Ferine
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Health Professions Medicine & Pharmacology Public Health

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Immunomodulatory Effect of Nigella sativa Extract through the Improvement of IL-1β Level in Balb-c Mice Infected by Methicillin-resistant Staphylococcus aureus Nitihapsari, Galuh Yulieta; S, Octavia Permata; Ferine, Miko
Jurnal Kedokteran Brawijaya Vol 31, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2020.031.02.3

Abstract

Nigella sativa (NS) has been used for many years as an anti-bacterial herbal treatment, such as Methicillin-resistant Staphylococcus aureus, but the mechanism in bacterial elimination is still unknown. IL-1β is a proinflammatory cytokine that helps the immune system eliminate microbes when it enters the body. The purpose of this study was to prove the immunomodulatory effects of Nigella sativa extract through increased IL-1β in dealing with MRSA infections. The design of this study was post-test only control group design using 25 male Balb-c mice infected with MRSA and randomly divided into five groups. Group K was infected with MRSA without being treated. All treatment groups were given NS extracts in different doses for 7 days before being infected with MRSA. P1 was given N. sativa extract 0.05ml, P2 (was given NS extract 0.25ml, P3 was given 0.5ml NS extract, and P4 was given 0.75ml NS. On the 8th day, blood was taken from the retroorbital plexus for IL-1β level examination using ELISA. Statistical tests were done using the One Way ANOVA test. The results showed the mean of IL-1β levels in group K was 11.65ng/L, P1 was 14.07ng/L, P2 was 16.66ng/L, P3 was 18.54ng/L, and P4 was 19.49ng/L which showed an increase in IL-1β levels along with the addition of black cumin dose although there was no difference between groups (p=0.578: ANOVA test). Nigella sativa extract is not proven effective in increasing IL-1β levels of Balb-c mice infected with MRSA.
PROFIL MOTIVASI MAHASISWA BARU MEMILIH JURUSAN KEDOKTERAN: STUDI DESKRIPTIF PADA 8 UNIVERSITAS DI INDONESIA Sallazaria Hanin Prameswari Syafiqa Ardli; Miko Ferine; Arfi Nurul Hidayah; Wahyudin Wahyudin; zainuddin zainuddin
Medical and Health Journal Vol 1 No 1 (2021): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (307.076 KB) | DOI: 10.20884/1.mhj.2021.1.1.4675

Abstract

Kedokteran merupakan salah satu jurusan di perguruan tinggi yang paling diminati. Jurusan ini dikenal mempunyai masa studi yang panjang dan proses yang sulit sehingga memerlukan motivasi yang kuat untuk menempuh semua tahap dalam pendidikan kedokteran. Oleh karena itu, perlu diketahui informasi mengenai jenis motivasi dan faktor-faktor yang mempengaruhi motivasi mahasiswa baru dalam memilih jurusan kedokteran di Indonesia. Penelitian ini bertujuan untuk mengetahui berbagai jenis motivasi serta faktor-faktor yang mempengaruhi motivasi mahasiswa baru angkatan 2020/2021 dalam memilih jurusan kedokteran di Indonesia. Penelitian ini menggunakan metode penelitian kuantitatif dengan desain penelitian deskriptif. Subjek penelitian diambil dengan menggunakan cluster sampling dengan jumlah 370 mahasiswa baru angkatan 2020/2021. Penelitian ini diukur menggunakan kuesioner yang dikembangkan dengan konsep dari Orsini et al. serta menggunakan analisis univariat untuk mendeskripsikan hasil penelitian. Hasil penelitian ini menunjukkan bahwa 55,4% dari subjek penelitian memiliki motivasi intrinsik yang lebih dominan, 30% memiliki motivasi ekstrinsik lebih dominan, dan 14,6% memiliki motivasi intrinsik dan ekstrinsik sama besarnya. Faktor-faktor yang mempengaruhi motivasi adalah faktor intrapersonal, interpersonal, kognitif, afektif, perilaku pribadi, karakteristik pribadi, karakteristik profesi, kondisi lingkungan kerja, dan peran keluarga. Kesimpulan penelitian ini menunjukkan bahwa mahasiswa baru memiliki motivasi intrinsik yang lebih dominan/tinggi dibanding motivasi ekstrinsik. Adapun faktor-faktor yang sangat mempengaruhi dalam memilih jurusan kedokteran di Indonesia adalah faktor intrapersonal, kognitif, karakteristik pribadi, karakteristik profesi, kondisi lapangan kerja, dan peran keluarga, sedangkan faktor interpersonal, afektif, dan perilaku pribadi kurang berpengaruh. Kata Kunci: Kedokteran, mahasiswa baru Motivasi, pendidikan kedokteran Tahun pertama
PERAN KELUARGA DALAM MENDUKUNG PASIEN DENGAN PENYAKIT TERMINAL: PELAJARAN DARI BANYUMAS – JAWA TENGAH Dyah Woro Dwi Lestari; Miko Ferine; Arfi Nurul Hidayah; Amalia Muhaimin; Bagas Wicaksono
Medical and Health Journal Vol 2 No 1 (2022): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (250.648 KB) | DOI: 10.20884/1.mhj.2022.2.1.7559

Abstract

Menyampaikan berita buruk dianggap sebagai salah satu bagian tersulit dari komunikasi antara dokter dan pasien. Dengan demikian pasien dan keluarga berhak memahami kondisi kesehatannya yang sebenarnya. Menyampaikan berita buruk dapat menyebabkan situasi yang tidak nyaman ketika pasien dan keluarga mereka menunjukkan reaksi negatif terhadap percakapan tersebut. Selain itu, situasi seperti itu dapat menyebabkan pengalaman negatif dan dapat berkembang menjadi pengalaman emosional yang buruk antara dokter dan pasien. Masalah komunikasi diidentifikasi sebagai faktor utama dalam menyampaikan berita buruk. Di sisi lain, budaya, faktor utama yang menentukan hasil komunikasi, akan memainkan peran penting dalam situasi ini. Tulisan ini bertujuan untuk menggali peran keluarga dalam proses penyampaian kabar buruk dari dokter kepada pasiennya. Metode kualitatif dilakukan dalam makalah ini dengan menggunakan wawancara mendalam dengan 7 anggota keluarga pasien dalam kondisi terminal. Hasil penelitian menunjukkan beberapa tema, yaitu peran keluarga dalam menjaga kondisi emosi dan psikologis pasien, peran keluarga sebagai orang penting untuk diandalkan (dalam hal pengobatan), keluarga sebagai pengambil keputusan yang menentukan terapi bagi pasien dan juga berperan dalam komunikasi antara dokter dan pasien.
PROFILE OF MEDICAL STUDENTS' METACOGNITIVE SELF-REGULATED LEARNING STRATEGIES IN PBL GROUP DISCUSSION DURING THE LIMITED FACE-TO-FACE LEARNING PERIOD Widiartini, Catharina; Ferine, Miko
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 12, No 2 (2023): Juni
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.79356

Abstract

Background: The change in the learning environment, from fully online to limited face-to-face could affect the use of metacognitive self-regulated learning (SRL) strategies in carrying out Problem-Based Learning (PBL) group discussions as one of the main learning methods in the faculty of medicine in Indonesia or elsewhere. The study aimed to describe the profile of metacognitive SRL strategies in conducting PBL group discussions during the limited face-to-face learning period.Methods: This was a descriptive quantitative observational study conducted at The Faculty of Medicine, Universitas Jenderal Soedirman during the implementation of limited face-to-face learning in the even semester of 2021/2022. Undergraduate students selected by total sampling were asked to fill in a questionnaire that was adapted from the MSLQ. The frequency of a learning strategy application for each of the 22 examples of metacognitive SRL strategies differed into: never; rarely; frequently; or always.Results: The response rate was 57.93% (199 students). Most (70.4%) of the respondents were women and had an average of 19.6 years old. Learning strategies with the largest proportion of "always" and "frequently" applied (44.58% - 65.38%) were related to identifying reading/learning needs; learning from peer feedback; and keeping focus. Learning strategies with the largest proportion of "rarely" and "never" (30.12% - 53.13%) were related to monitoring and evaluating achievement and applying reflective learning.Conclusion: The profile of the implementation of learning strategies during the limited face-to-face learning period has been identified. Efforts need to be made to improve students' abilities in implementing learning strategies that are rarely and never used.
The Relationship Between Anatomy Identification Test Scores and The Suitability in V/A/R/K Modality Usage Between Study Habit and Learning Style Widiartini, Catharina; Ferine, Miko; Pribadi, Fajar Wahyu
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 13, No 2 (2024): June
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.92758

Abstract

Background: Mastery of Anatomy is essential to base learning in Medicine. However, the Anatomy identification test scores are often less than satisfactory. This problem could be caused by different usage of sensory modalities which were visual, aural, read/write, and kinaesthetic (V/A/R/K) between one’s study habit and his/her learning style. This study aimed to determine the relationship between Anatomy identification test scores and the suitability in V/A/R/K modality usage between study habits and learning styles.Method: This was an observational study of 103 first year students of the Faculty of Medicine Unsoed who were selected using total sampling, taking into account the inclusion criteria in the form of complete data availability for the three variables. Univariate statistical analyses were conducted for each variable as well as the suitability between study habits and learning style based on determined criteria. Relationship between Anatomy identification test scores and the suitability between V/A/R/K study habits and learning styles was analyzed using the Mann-Whitney test.Results: Most students had quadmodal learning style (27.2%), but unimodal visual study habit (21.4%). Most (64.1%) students had no suitability between study habits and learning styles, with the test score average was not significantly lower (p = 0.228) than those with suitability. Conclusion: There is no significant relationship between Anatomy identification test scores and the suitability between study habits and learning styles. Students may reflect on the result to modify their learning process further. Institution can provide opportunities for students with various characteristics to develop study habits that suit their learning styles.
Caught in the Crossfire: Doctors’ Battle with Emotional Strain and Resource Shortages (Lesson Learned from Covid-19 Pandemic) Lestari, Diyah Woro Dwi; Hidayah, Arfi Nurul; Ferine, Miko; Wicaksono, Raditya Bagas; Dinata, Ageng Bella; Muhaimin, Amalia; Octavilia, Ernasiwi Astri; Maghfiroh, Nisaul; Kamal, Isran
Medical and Health Journal Vol 5 No 1 (2025): August
Publisher : Fakultas Kedokteran Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.mhj.2025.5.1.15090

Abstract

Healthcare professionals, particularly doctors, navigate a delicate balance between empathy and emotional resilience, a challenge that became more pronounced during the COVID-19 pandemic. This study explores the experiences of doctors in managing empathy while coping with burnout, compassion fatigue, and resource scarcity. Through in-depth interviews with general practitioners and specialists, four key themes emerged: the emotional impact of patient conditions on doctors, the heightened burnout caused by excessive workloads, the distress of resource shortages, and the struggle to maintain professionalism despite emotional strain. Findings highlight the dual nature of empathy—while essential for patient care, it also contributes to emotional exhaustion. The study underscores the urgent need for systemic support, including psychological interventions and institutional strategies, to sustain healthcare professionals' well-being and ensure compassionate yet sustainable medical practice.
Co-Authors Amalia Muhaimin Arfi Nurul Hidayah Bagas Wicaksono Dinata, Ageng Bella Diyah Woro Dwi Lestari Fajar Wahyu Pribadi Hidayah, Arfi Nurul Kamal, Isran Lestari, Diyah Woro Dwi Maghfiroh, Nisaul Muhaimin, Amalia Nitihapsari, Galuh Yulieta Octavilia, Ernasiwi Astri S, Octavia Permata Sallazaria Hanin Prameswari Syafiqa Ardli Wahyudin Wahyudin Wicaksono, Raditya Bagas Widiartini, Catharina Zainuddin Zainuddin