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All Journal Jurnal Komputasi Jurnal Ilmu Administrasi: Media Pengembangan Ilmu dan Praktek Administrasi Indonesian Journal of Pharmacy and Natural Product BULLET : Jurnal Multidisiplin Ilmu Jurnal Ilmu Administrasi: Media Pengembangan Ilmu dan Praktek Administrasi Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Jurnal Komputasi
Muhammad Iqbal
Universitas Lampung
Humanities Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Electrical & Electronics Engineering Engineering Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Analisis Aktivitas Antioksidan Ekstrak Daun Katang-Katang (Ipomea pes caprae) dengan Metode DPPH : Literature Review Tsania Zahra Taslima; Zulpakor Oktoba; Atri Sri Ulandari; Muhammad Iqbal
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 1 (2025): Januari : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i1.594

Abstract

Free radicals are reactive molecules that contribute to oxidative stress, triggering cellular damage and leading to degenerative diseases such as cancer, diabetes, and cardiovascular diseases. Antioxidants are required to neutralize free radicals and protect the body from oxidative damage. The leaves of Ipomoea pes-caprae (L.) R. Br. contain secondary metabolites, such as flavonoids and phenolics, which have potential antioxidant activity. This article aims to analyze the antioxidant activity of Ipomoea pes-caprae leaf extract using the DPPH method. The study employed a literature review approach using Google Scholar with specific keywords and 13 articles met the inclusion criteria with a  publication range from 2015 to 2025. The findings indicate that the extraction method and type of solvent significantly affect the effectiveness of antioxidant activity. Maceration and Soxhlet extraction methods were effective in isolating active compounds, particularly flavonoids and phenolics, while polar solvents such as ethanol and methanol produced better results compared to non-polar solvents. Antioxidant strength, determined by IC50 values, ranged from very strong to very weak. Therefore, it can be concluded that selecting the appropriate extraction method and solvent is crucial to maximizing the antioxidant potential of Ipomoea pes-caprae leaves as a natural antioxidant source for health and pharmaceutical applications.  
Kandungan Senyawa Fitokimia dan Aktivias Antioksidan dari Ekstrak Daun Alpukat (Persea americana Mill.) : Narrative Review Michelle Jovelyna My Angel Pasaribu; Ihsanti Dwi Rahayu; Muhammad Iqbal; Ari Sri Ulandari
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 2 (2025): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i2.597

Abstract

Avocado leaves have long been used by Indonesian people as traditional medicine. Many studies have shown that the plant has many active compounds that have the potential to prevent cell damage caused by free radicals. The purpose of this narrative review article is to collect and review references related to the phytochemical compound content and potential antioxidant activity of avocado leaf extract (Persea americana Mill.). The search and review of literature used in writing this article was carried out by searching for reference sources by combining relevant keywords such as "antioxidant AND persea americana leaves* AND extract" on database sites such as NCBI, ScienceDirect, and Google Scholar. There are inclusion criteria used, namely articles in English and Indonesian, available in full text form, discussing secondary metabolite compounds of avocado leaf extract using the maceration method, and discussing antioxidant activity tests using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Based on the search results, there are 7 articles that have met the inclusion criteria and have been reviewed. The results of this narrative review obtained information that there were several studies that conducted antioxidant activity tests on avocado leaf extract using the DPPH method with an IC50 value range of 6.7-440.80 µg/ml and there were polyphenol compounds, especially quercetin and kaempferol which contributed to the antioxidant activity of avocado leaves.
Co-Authors Andrian, Rico Ari Sri Ulandari Atri Sri Ulandari Bambang Hermanto Citra Yuliyanda Pardilawati Dika Pramita Destiani, Dika Pramita Dwi Aulia Ramdini Febi Eka Febriansyah Heningtyas, Yunda Ihsanti Dwi Rahayu Malik Abdul Aziz Michelle Jovelyna My Angel Pasaribu Muhammad Ridho Nara Safitri Oktoba, Zulpakor Paul Benyamin Timotiwu Ramadhan Triyandi Rasmi Zakiah Oktarlina Sarmoko Sarmoko Tsania Zahra Taslima Wawan Abdullah Setiawan