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All Journal MARINA CHIMICA ACTA PROSIDING SEMINAR KIMIA KOVALEN: Jurnal Riset Kimia Indonesia Chimica Acta Panrita Abdi - Jurnal Pengabdian pada Masyarakat Al-Kimia Indonesian Journal of Chemistry Communications in Science and Technology SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Keperawatan Muhammadiyah

Indah Raya

Chemistry Department, Faculty Of Mathematics & Natural Sciences Hasanuddin University

Author-ID : 2671967

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Pemanfaatan Kitin Sebagai Bahan Membran Elektroda Enzim Diamin Oksidase Untuk Biosensor Histamin Abdul Karim; Abd. Rauf Patong; Abd. Wahid Wahab; Indah Raya
Al-Kimia Vol 2 No 2 (2014): Desember
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

This research aims to utilize isolated chitin from shrimp waste to develop histamine biosensors basedon diamine oxidase (DAO) enzyme electrode with cyclic voltammetry. DAO enzyme trapped in the chitin-cellulose acetate membranes with various comparisons were layered on the Pt electrode. Histamine will be oxidized by the DAO enzyme produces aldehydes and H2O2 which acts as an electron transfer mediator. Biosensor performance is influenced by several factors, especially the concentration and composition of electrode membranei.Comparison of chitin-cellulose acetate used in this study were 1:1, 2:1 and 3:1. Isolated chitin from the shrimp waste is chemically obtainedrendamen of 23.6%, and characterization of electrode membrane by FTIR and cyclic voltammetry showed that the DAO enzymes electrode with chitin-cellulose acetate membrane 2:1 is the best composition.

Optimasi Penggunaan Hidrogen Peroksida (H2O2) Terhadap Penurunan Kadar Sianida Pada Limbah Cair Muntasir Muntasir; M. Sjahrul; Muhammad Zakir; Indah Raya
Al-Kimia Vol 3 No 2 (2015): December
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Optimation studies have been conducted using hydrogen peroxide (H2O2) to the reduction of cyanide levels in the wastewater. Parameters studied were the optimum concentration of hydrogen peroxide (H2O2), the optimum pH and optimum contact time between hydrogen peroxide (H2O2) with wastewater in reducing the cyanide content. Cyanide obtained from steam distillation of liquid waste and the assay using 0.02N silver nitrate. Concentration used were 500 ppm, 400 ppm, 300 ppm, 200 ppm and 100 ppm; pH range is (7, 8, 9, 10 and 11) and the variation of the contact time is: 0, 30, 60, 90, 120 and 150 minutes. The result of the research reveals at early treatment the cyanide content is 50,22% w / w and underwend a reduction in levels after addition of various concentrations of H2O2; variations in pH variation of contact time. Optimum condition treatment at 500 ppm of H2O2 basicity at pH 8 and contact time for 60 minutes result reduction of cyanide level of 36,40% w/w, 40,91% w/w and 37,09% w/w respectively.

Docking Molecular dari Kompleks Zn(II)Amina (Prolin)dithiokarbamat terhadap Reseptor Estrogen-α Rizal Irfandi; Ruslang Ruslang; Indah Raya; Ahmad Yani; Muhammad Nasir; Nurcaya Nurcaya; Sulistiani Jarre
Al-Kimia Vol 9 No 2 (2021): DESEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v9i2.23949

Estrogen-α (ER-α) is a major target in cancer therapy. Targeting the ER-α target protein is known to slow the proliferation of breast cancer cells. The purpose of this study was to determine the interaction of the complex compound Zn(II)Prolinedithiocarbamate against the Estrogen-α Receptor. The Zn(II)Prolinedithiocarbamate complex was predicted canonical SMILE by Cheminfo online application (O=C(O)C1CCCN1C2S[Zn]S2) and modeled with online corina to obtain a three-dimensional structure. The structure of the complex compound Zn(II)Prolinedithiocarbamate interacted with Estrogen receptor alpha protein to test its potential anticancer activity. Molecular docking results show the interaction of the Zn(II)Prolinedithiocarbamate complex with the Estrogen- receptor on the amino acid residues ARG394, LEU387, GLU353, LEU346, LEU349, and PHE404. The Zn(II)Prolinedithiocarbamate complex interacts directly with ER-α in the estrogen region which causes the failure of the interaction between estrogen and the estrogen receptor, so it can be predicted that the Zn complex has activity as an ER-α inhibitor and has the potential to be developed in the treatment of breast cancer.

Co-Authors -, Emmasitah Abd. Rauf Patong Abd. Wahid Wahab Abdul Karim Abdul Wahid Wahab Abdul Wahid Wahab Ahmad Yani Ahmar, Hamdiah Ahyar Ahmad Alfani M Datu Andi Evi Erviani Andi Muhammad Anshar Andi Nilawati Usman Anita Anita Annisa Eka Permatasari Asbia Asbia Bambang Rusdiarso Erna Mayasari Fitria Aziz Gita Gita Hasnah Natsir Hasnah Natsir Hasnah Natsir Herlina Rasyid Husnul Khotimah Irfandi, Rizal Jayawarsa, A.A. Ketut M. Sjahrul M. Sjahrul Maming Mauludiyah, Indah Muh. Nur Alam Muh. Yusri Karim Muhammad Nadir Muhammad Zakir Muhammad Zakir Muhammad Zakir Muhammad Zakir Muntasir, Muntasir Musa Ramang Narsito Narsito Nurcaya Nurcaya Nurrahmi Umami Nursiah La Nafie Nursiah La Nafie Paulina Taba Prihartini, Ade Rahayu Rahmah Rahmah Raymond Kwangdinata Ridhawati Thahir Riska Mardiyanti Rugaiyah A. Arfah Ruslan Ruslan Ruslang, Ruslang St Fauziah Sulistiani Jarre Syaharuddin Kasim Syahruddin Kasim Tuti Sukini Usman, Andriani Wahda, Indah Wahyudin Rauf Windasari Yudiarsi Eppang Yusafir Hala Yusafir Hala

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