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Gambaran Infeksi Nontuberculous Mycobacteria (NTM) pada Penderita Suspek TB Paru Menggunakan Multiplex PCR (MPCR)-Universal Lateral Flow Assay (ULFA) Kit Putri Wulan Akbar; Agustin Iskandar; Tri Wahju Astuti; Kristin Indriana
Jurnal Kesehatan Andalas Vol 9, No 3 (2020): Online September 2020
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i3.1394

Abstract

Infeksi paru akibat Nontuberculous Mycobacteria (NTM) dan Mycobacterium tuberculosis (MTB) dapat memberikan gambaran klinis yang serupa sehingga berpotensi menyebabkan kesalahan diagnosis dan terapi. Pemeriksaan Multiplex PCR (MPCR)-Universal Lateral Flow Assay (ULFA) merupakan pemeriksaan berbasis molekuler untuk mendeteksi gen rpoB, IS1660 dan mtp40 yang dapat digunakan untuk membedakan infeksi NTM dari infeksi TB. Tujuan:  Mendapatkan gambaran infeksi NTM menggunakan MPCR-ULFA pada penderita terduga TB paru. Metode: Penelitian ini merupakan studi deskriptif dengan pendekatan potong lintang yang dilaksanakan sejak April sampai Juli 2019. Sebanyak 39 sampel sputum dari pasien terduga TB paru dari RSUD Kanjuruhan Kepanjen, Kabupaten Malang diperiksakan apusan BTA, GeneXpert dan MPCR-ULFA. Hasil: Sebanyak 5 sampel (12,8%) sputum dari pasien terduga TB paru terdeteksi sebagai NTM positif menggunakan pemeriksaan MPCR-ULFA. Empat dari lima sampel (80%) tersebut memiliki kesesuaian dengan hasil GeneXpert dan apusan BTA, yakni MTB negatif.  Pemeriksaan molekuler baik GeneXpert maupun MPCR-ULFA keduanya mendeteksi keberadaan gen rpoB dari Mycobacterium. Metode MPCR-ULFA mengamplifikasi 3 gen target sekaligus (IS1660, mtp40 dan rpoB) sehingga dapat mendeteksi infeksi NTM atau MTB. Simpulan: Prevalensi NTM pada pasien terduga TB paru di RSUD Kanjuruhan Kepanjen menggunakan MPCR-ULFA mencapai 12,8%. Sebanyak 80% dari NTM positif memiliki hasil pemeriksaan GeneXpert dan apusan BTA negatif.Kata kunci: GeneXpert, MPCR-ULFA, NTM, suspek TB paru
The Relationship Between Proteinuria Degree of Pre-eclampsia Mother and Incidence of Neonatal Low Birth Weight at General Hospital Karsa Husada Batu Yuwan Ihzudin Sumitro; Alifia Putri Febriyanti; Prida Ayudianti; Putri Wulan Akbar; Nurfianti Indriana
Journal of Agromedicine and Medical Sciences Vol 9 No 3 (2023)
Publisher : Faculty of Medicine, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i3.42833

Abstract

Preeclampsia is hypertension that occurs after 20 weeks of gestation with proteinuria. As one of the second highest causes of maternal death in Indonesia, preeclampsia must be detected and managed quickly and appropriately before complications that threaten the mother and fetus arise. One of the conditions that can be associated with preeclampsia is the outcome of low birth weight babies (LBW). This study aimed to determine the relationship between the degree of proteinuria in preeclampsia mothers and incidence of LBW at RSU Karsa Husada Batu. This study used a cross-sectional study design. Data was collected from medical record. The independent variable in this study was the degree of proteinuria and the dependent variable was diagnosis of LBW. The population in this study were all preeclampsia mothers and their babies from preeclampsia patients at RSU Karsa Husada Batu in 2021 with total of 38 patient. Sampling was done by total population sampling. Data analysis used in the study is chi square test. The results of this study showed that there is a relationship between the degree of proteinuria in preeclampsia mothers and incidence of LBW or the higher the degree of proteinuria, the higher the risk of babies from preeclampsia patients experiencing LBW ( p=0,005 ; CI = 95%). Keywords: Preeclampsia, Proteinuria, LBW
Gambaran Infeksi Nontuberculous Mycobacteria (NTM) pada Penderita Suspek TB Paru Menggunakan Multiplex PCR (MPCR)-Universal Lateral Flow Assay (ULFA) Kit Akbar, Putri Wulan; Iskandar, Agustin; Astuti, Tri Wahju; Indriana, Kristin
Jurnal Kesehatan Andalas Vol. 9 No. 3 (2020): Online September 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i3.1394

Abstract

Infeksi paru akibat Nontuberculous Mycobacteria (NTM) dan Mycobacterium tuberculosis (MTB) dapat memberikan gambaran klinis yang serupa sehingga berpotensi menyebabkan kesalahan diagnosis dan terapi. Pemeriksaan Multiplex PCR (MPCR)-Universal Lateral Flow Assay (ULFA) merupakan pemeriksaan berbasis molekuler untuk mendeteksi gen rpoB, IS1660 dan mtp40 yang dapat digunakan untuk membedakan infeksi NTM dari infeksi TB. Tujuan:  Mendapatkan gambaran infeksi NTM menggunakan MPCR-ULFA pada penderita terduga TB paru. Metode: Penelitian ini merupakan studi deskriptif dengan pendekatan potong lintang yang dilaksanakan sejak April sampai Juli 2019. Sebanyak 39 sampel sputum dari pasien terduga TB paru dari RSUD Kanjuruhan Kepanjen, Kabupaten Malang diperiksakan apusan BTA, GeneXpert dan MPCR-ULFA. Hasil: Sebanyak 5 sampel (12,8%) sputum dari pasien terduga TB paru terdeteksi sebagai NTM positif menggunakan pemeriksaan MPCR-ULFA. Empat dari lima sampel (80%) tersebut memiliki kesesuaian dengan hasil GeneXpert dan apusan BTA, yakni MTB negatif.  Pemeriksaan molekuler baik GeneXpert maupun MPCR-ULFA keduanya mendeteksi keberadaan gen rpoB dari Mycobacterium. Metode MPCR-ULFA mengamplifikasi 3 gen target sekaligus (IS1660, mtp40 dan rpoB) sehingga dapat mendeteksi infeksi NTM atau MTB. Simpulan: Prevalensi NTM pada pasien terduga TB paru di RSUD Kanjuruhan Kepanjen menggunakan MPCR-ULFA mencapai 12,8%. Sebanyak 80% dari NTM positif memiliki hasil pemeriksaan GeneXpert dan apusan BTA negatif.Kata kunci: GeneXpert, MPCR-ULFA, NTM, suspek TB paru
THE INFLUENCE OF HANDPHONES ON STUDENTS' LEARNING MOTIVATION OF MI HASYIM ASY'ARI PADI TALANGSUKO Apriliani, Defina Dwi; Amala, Afdhirotul Isna; Pudiarti, Alya Arung; Akbar, Putri Wulan
JRCE (Journal of Research on Community Engagement) Vol 5, No 2 (2024): Journal of Research on Community Engagement
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jrce.v5i2.19936

Abstract

In the era of digitalization, which is very fast, it has no small impact, the decline in the quality and level of student learning is one that is rife, caused by none other than cellphones. This research aims to find out how much influence mobile phones have on learning motivation at MI Hasyim Asy'ari Padi Talangsuko Malang Regency. This research method uses descriptive qualitative. The data collection technique was in the form of a survey via Google form containing questions about the use of cell phones associated with learning consistency. The data analysis used is data reduction, data presentation, conclusion/data verification. The results of the study show that students stated that the use of smartphones had a positive impact on respondents by 80%. This shows that the percentage of 80% is in the high category, and it can be said that students agree that the use of smartphones has a positive impact on the teaching and learning process.
Social Support Build Resilience in Multidrug-Resistant Tuberculosis Patients: A Cross-Sectional Study in MDR-TB Patient Support Group Akbar, Putri Wulan; Rachma, Lailia Nur; Rahmah, Zainabur; Firdaus, Muhammad Iqbal; Nanggali, Bryka Vian
The Avicenna Medical Journal Vol 5, No 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.42615

Abstract

Background: Multidrug-resistant tuberculosis (MDR-TB) patient faces multi-dimensional challenges due to the physical factor, long-term treatment, negative stigma, and psychosocial challenge. Addressing these issues patient requires a resilience. The formation of resilience is influenced by both internal and external factors, including social support. This study purposed to assess the social support impact on resilience in MDR-TB patients. Methods: This study was an observational analytic study with cross sectional design. A total of 33 respondents with MDR-TB confirmed, a member of MDR-TB support group, and under treatment were involved. The social support level was measured using the ISEL-12 (Interpersonal Support Evaluation List) questionnaire, while the level of resilience was assessed using the CD-RISC-25 (Connor-Davidson Resilience Scale). Spearman correlation test in SPSS Ver 24.0 was used to examine the relationship between social support and resilience among patients with MDR-TB. Results: Majority of respondents (17 respondents, 51.6%) have good social support and 23 respondents (69.7%) exhibited a good level of resilience. The Spearman correlation test revealed a significant positive correlation between social support and resilience, with a p-value of 0.030 and a moderate strength correlation coefficient (r) of 0.378. Conclusion: This finding showed that good social support toward MDR-TB patients gives positive impact to patients’ resilience. Thus strengthens the system of social support in support group is important to decrease the psychosocial challenges and help to succeed the treatment.
Social Support Build Resilience in Multidrug-Resistant Tuberculosis Patients: A Cross-Sectional Study in MDR-TB Patient Support Group Akbar, Putri Wulan; Rachma, Lailia Nur; Rahmah, Zainabur; Firdaus, Mohammad Iqbal; Nanggali, Bryka Vian
The Avicenna Medical Journal Vol. 5 No. 2 (2024): The Avicenna Medical Journal
Publisher : Faculty of Medicine, UIN Syarif Hidayatullah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/avicenna.v5i2.46875

Abstract

Background: Multidrug-resistant tuberculosis (MDR-TB) patient faces multi-dimensional challenges due to the physical factor, long-term treatment, negative stigma, and psychosocial challenge. Addressing these issues patient requires a resilience. The formation of resilience is influenced by both internal and external factors, including social support. This study purposed to assess the social support impact on resilience in MDR-TB patients. Methods: This study was an observational analytic study with cross sectional design. A total of 33 respondents with MDR-TB confirmed, a member of MDR-TB support group, and under treatment were involved. The social support level was measured using the ISEL-12 (Interpersonal Support Evaluation List) questionnaire, while the level of resilience was assessed using the CD-RISC-25 (Connor-Davidson Resilience Scale). Spearman correlation test in SPSS Ver 24.0 was used to examine the relationship between social support and resilience among patients with MDR-TB. Results: Majority of respondents (17 respondents, 51.6%) have good social support and 23 respondents (69.7%) exhibited a good level of resilience. The Spearman correlation test revealed a significant positive correlation between social support and resilience, with a p-value of 0.030 and a moderate strength correlation coefficient (r) of 0.378. Conclusion: This finding showed that good social support toward MDR-TB patients gives positive impact to patients’ resilience. Thus strengthens the system of social support in support group is important to decrease the psychosocial challenges and help to succeed the treatment.
Promosi Kesehatan dalam Rangka Peningkatan Pengetahuan Interaksi Obat - Makanan pada Masyarakat Febriyanti, Alifia Putri; Putri Wulan Akbar; Qoriah Nur Alfaizah; Mochammad Rif’al Maulana Ilham; Rosadian Maharani; Yashinta Avrilia Rahma
CARADDE: Jurnal Pengabdian Kepada Masyarakat Vol. 7 No. 1 (2024): Agustus
Publisher : Ilin Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31960/caradde.v7i1.2216

Abstract

Tujuan kegiatan pengabdian adalah untuk meningkatkan pengetahuan mengenai interaksi obat dengan makanan/minuman kepada warga RT.01 RW. 02, Dusun Krajan, Sumbersekar. Metode digunakan dalam pengabdian ini yaitu Participatory Action Research (PAR) dengan rentang usia 40-60 tahun. Metode pengabdian ini terdiri dari tiga tahap yaitu tahap pra pelaksanaan, tahap pelaksanaan, dan tahap evaluasi. Tahap pra pelaksanaan dijelaskan terkait deskripsi kegiatan, menentukan tujuan, sasaran, tempat, dan waktu pelaksanaan kegiatan yang akan dilakukan. Tahap pelaksanaan dilakukan secara door to door dengan menggunakan media leaflet. Tahap evaluasi dilakukan dengan memberikan pre-test dan post-test kepada warga. Hasil kegiatan pengabdian ini menunjukkan bahwa adanya peningkatan nilai evaluasi yang awalnya pada pre-test sebesar 63,3% menjadi 100 % pada post-test dengan kategori baik. Disimpulkan bahwa kegiatan penyuluhan secara door to door dengan media leaflet terbukti efektif dalam memberikan pengetahuan kepada warga RT.01 RW. 02, Dusun Krajan, Sumbersekar.