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All Journal Public Health of Indonesia Jurnal Mirai Management Jurnal Kesehatan Manarang Afiasi : Jurnal Kesehatan Masyarakat Narra J Buletin Kesehatan MAHASISWA
Hasanuddin Ishak
kesehatan lingkungan
Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Karakteristik Lingkungan Penderita Malaria di Kabupaten Bulukumba Irawati, Irawati; Ishak, Hasanuddin ; Arsin, Arsunan
Afiasi : Jurnal Kesehatan Masyarakat Vol 2 No 3 (2107): Afiasi
Publisher : Universitas Wiralodra

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (546.075 KB)

Abstract

Kabupaten Bulukumba menjadi wilayah endemis malaria dalam beberapa tahun terakhir. Penelitian ini bertujuan untuk menganalisis karakteristik lingkungan dalam rumah penderita malaria di Kabupaten Bulukumba. Penelitian ini dilaksanakan pada lima wilayah puskesmas dan satu rumah sakit di Kabupaten Bulukumba yang memiliki data kasus malaria tertinggi pada 2 tahun terakhir. Metode yang digunakan adalah observational dengan desain case control study. Pengambilan sampel diambil dari catatan rekam medik pemeriksaan sediaan darah di laboratorium yang dinyatakan positif mengandung Plasmodium. Hasil penelitian menunjukkan bahwa  Faktor lingkungan dalam rumah yang berpengaruh secara signifikan terhadap kejadian malaria adalah pencahayaan dalam  rumah (p-value= 0,00, OR= 0,125, 95% CI= 0,020-0,7821) di wilayah kerja puskesmas Ujung Loe, dan pakaian tergantung (p-value= 0,05, OR= 6,000, 95% CI= 1,315-4,579) di wilayah kerja bonto tiro, sedangkan faktor lingkungan dalam rumah yang tidak memiliki risiko secara signifikan adalah kondisi dinding, pemasangan kawat kasa, dan keberadaan langit-langit. Diharapkan kepada masyarakat agar memperbaiki pola lingkungan hidup bersih dan sehat sehingga meminimalkan faktor risiko kejadian malaria.
ANALISIS RISIKO KESEHATAN LINGKUNGAN PAJANAN DEBU PM10 PADA RELAWAN LALU LINTAS DI JALAN URIP SUMOHARJO KOTA MAKASSAR Harnia, Harnia; Ishak, Hasanuddin; Ikhtiar, Muhammad; Bintara, Agus; Habo, Hasriwiani; Arman, Arman
Jurnal Mirai Management Vol 4, No 2 (2019)
Publisher : STIE AMKOP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.258 KB) | DOI: 10.37531/mirai.v4i2.653

Abstract

Hasil penelitian menunjukkan bahwa, nilai konsentrasi minimum PM10 adalah 18,75 μg/Nm3, maksimum 41,27 μg/Nm3, dan rata-rata 33,49 µg/Nm3. Hasil perhitungan Intake dengan nilai minimum sebesar 0,00015 mg/kg/hari, maksimum 0,00341 mg/kg/hari dan Intake rata-rata sebesar 0,00027 mg/kg/hari. Perhitungan RQ menunjukkan bahwa RQ dalam konsentrasi minimum 0,01 mg/kg/hari konsentrasi maksimum 0,24 mg/kg/hari, dan konsentrasi rata-rata 0,01 mg/kg/hari. Nilai RQ pada konsentrasi minimum, maksimum dan rata-rata menunjukkan RQ< 1 dengan demikian, tingkat risiko bagi relawan lalu lintas atau pallimbang-limbang masih aman. Meskipun konsentrasi risiko ini masih berada di bawah baku mutu, tidak dapat membebaskan seluruh populasi dari risiko gangguan kesehatan. Hal ini dapat dilihat dari keluhan responden berupa gangguan kesehatan seperti batuk, sakit kepala, sesak nafas dan iritasi pada mata. Hasil estimasi tingkat risiko pada relawan lalu lintas dengan konsentrasi maksimum menunjukkan bahwa dalam 10 tahun ke depan relawan lalu lintas sudah tidak aman lagi. Kata Kunci: Particulate Matter (PM10), Analisis Risiko Kesehatan Lingkungan, Relawan Lalu Lintas, Jl. Urip Sumoharjo Kota Makassar.
Impact of early-life malaria exposure on childhood stunting: A case-control study in high endemic malaria area, Papua, Indonesia Sahiddin, Muhamad; Ishak, Hasanuddin; Arsin, Andi A.; Pramestiyani, Mustika
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.1451

Abstract

Papua faces public health challenges as a region with high malaria endemicity and a very high prevalence of stunting. Infectious diseases are one of the risk factors for stunting. The aim of this study was to investigate the effect of early-life malaria exposure on stunting among children in Papua. The study was conducted in 14 public health centers (PHCs) in Papua in 2023. Six hundred eighty-one children (227 stunted and 454 non-stunted) were selected using simple random sampling. The study data were gathered from medical records, structured parent interviews, and direct anthropometric measurements of the children. Chi-square tests were performed to determine unadjusted OR, while adjusted OR was calculated using multivariate analysis. The height-for-age z-score was calculated using WHO Anthro version 3.2.2. The results showed that 45.1% of mothers who had malaria during pregnancy had stunted children. The average z-score height-for-age of children from mothers who experienced malaria during pregnancy vs those who did not was -1.69±1.23 vs -1.41±1.55. Among the 84 children who had malaria under one year old, 45.2% experienced stunting. The average z-score height-for-age of children who had malaria under one year old vs those who did not was -1.83±1.24 vs -1.38±1.6. In the unadjusted analysis, malaria during pregnancy (OR 1.74; 95%CI:  1.06–2.87), malaria in children under one year old (OR 1.78; 95%CI: 1.12–2.83), low birth weight status (OR 1.82; 95%CI: 1.08–3.05), family income (OR 1.75; 95%CI: 1.09–2.81), and mother’s ethnicity (OR 1.45; 95%CI: 1.05–2.01) were associated with stunting incidence in children. In the multivariate analysis, mother’s ethnicity (aOR 1.41; 95%CI: 1.00–1.97) and low birth weight status (aOR 1.72; 95%CI: 1.00–2.94) were the only risk factor for stunting. This study suggests a potential association between early-life malaria exposure and stunting in children. In malaria-endemic areas, health interventions targeting malaria prevention during pregnancy and early childhood are necessary to reduce the risk of stunting.
Resistance status of Aedes mosquitoes as dengue vectors and the potential of plant larvicides from Indonesia for biological control: A narrative review Kasman, Kasman; Ishak, Hasanuddin; Alam, Gemini; Amiruddin, Ridwan; Hastutiek, Poedji; Arsin, Andi A.; Nasir, Sudirman; Ridha, Muhammad R.; Wahid, Isra
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1819

Abstract

Dengue fever remains a major public health threat in Indonesia, exacerbated by rising insecticide resistance in Aedes aegypti. Strategies relying on chemical insecticides, while initially effective, have led to widespread resistance in mosquito populations. This resistance is particularly pronounced in areas such as Java, where the extensive use of insecticides, including organophosphates and pyrethroids, has been documented. To address this challenge, one promising alternative is the utilization of biolarvicides derived from local Indonesian plant materials. Biolarvicides are environmentally friendly, safe, and have the potential to mitigate the adverse impacts associated with chemical insecticides. Numerous studies have explored the larvicidal properties of indigenous plants native to Indonesia, demonstrating their efficacy against A. aegypti. The aim of this study was to examine insecticide resistance in Aedes mosquitoes across Indonesia, highlighting geographical variations and underexplored regions, and exploring plant-based biolarvicides as sustainable alternatives.  Biolarvicides derived from native Indonesian plants could be eco-friendly alternative for dengue vector management. Their integration into existing control strategies could significantly enhance efforts to control dengue while reducing the environmental and health risks posed by chemical insecticides.
Environmental Analysis Of The Aedes Aegypti Mosquito As Dhf Vector In The Enrekang District Alamsyah, Dicky; Manyullei, Syamsuar; Ishak, Hasanuddin
Jurnal Kesehatan Manarang Vol 10 No 1 (2024): April 2024
Publisher : Politeknik Kesehatan Kemenkes Mamuju

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33490/jkm.v10i1.1158

Abstract

Dengue Hemorrhagic Fever is a major health problem in Indonesia. The existence of the Aedes Aegypti mosquito is the main vector that causes Dengue Hemorrhagic Fever (RI Ministry of Health, 2020). The physical environment of the Aedes Aegypti mosquito greatly influences the ecology and development of the Aedes Aegypti mosquito, which is the main factor causing Dengue Hemorrhagic Fever (Listiono et al, 2020). The incidence of Dengue Fever in the people of Enrekang Regency is influenced by the physical environment of the Aedes Aegypti mosquito. Data on the physical environment of the Aedes Aegypti mosquito in the Enrekang Regency area is inadequate. In the Enrekang district area, there were 166 cases of dengue fever in 2019, in 2020 there was an increase of 209 cases and there was a decrease again in 2021 with 64 cases. Cases of Dengue Hemorrhagic Fever sufferers in Enrekang district are among the 10 highest diseases. The aim of the research is to determine the relationship between the physical environment (temperature, pH, humidity and residential density) of the Aedes Aegypti mosquito and the incidence of Dengue Hemorrhagic Fever in Enrekang district. The method in this research is analytical observational using a Case Control study approach. Analytical observational research is research that tries to identify how health phenomena occur. Sampling was carried out using the total sampling method. Data was obtained directly from the Enrekang District health office. The research results showed that there was a significant relationship between room temperature, water pH and room humidity with the incidence of Dengue Hemorrhagic Fever in Enrekang district with respective p-values of (0.007, 0.001 and 0.000). The results of the research show that the physical environment of the Aedes Aegypti mosquito is a risk factor for the occurrence of Dengue Fever in Enrekang district.
Efek Larvasida Daun Jarak Kepyar (Ricinus communis linn) pada Organisme non-target : Larvicidal Effect of Castor Leaves (Ricinus communis linn) on non-Target Organisms Dwicahya, Bambang; Arsin, A. Arsunan; Ishak, Hasanuddin; Hamid, Firdaus
Buletin Kesehatan Mahasiswa Vol. 4 No. 2 (2026): Buletin Kesehatan MAHASISWA
Publisher : Fakultas Kesehatan Masyarakat Universitas Tompotika Luwuk Banggai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51888/jpmeo.v4i2.405

Abstract

Penyakit Demam Berdarah Dengue (DBD) masih menjadi masalah kesehatan yang signifikan, termasuk Indonesia. Tanaman jarak kepyar telah diketahui memiliki sifat larvasida terhadap larva nyamuk aedes pada beberapa penelitian, namun perlu dilakukan studi tentang pengaruh efek residu larvasida daun jarak kepyar untuk mengevaluasi risiko potensial dan efek jangka Panjang dan peninjauan ekstrak daun jarak kepyar terhadap organisme non-target. Metode penelitian  larvasida ekstrak daun jarak kepyar dilakukan menggunakan metode maserasi. Pembuatan ekstrak daun jarak kepyar menggunakan 4 jenis pelarut yang berbeda. Bahan Daun Jarak Kepyar dibagi menjadi dua yaitu daun muda dan daun tua. efek pada organisme non-target dilakukan pengamatan sampai pada hari ke-7 setelah perlakuan. Hasil penelitian menunjukkan efek ekstrak daun jarak (menggunakan 4 pelarut) baik daun muda maupun daun tua terhadap organisme non-target (ikan guppy) tidak menimbulkan mortalitas pada ikan selama 3 kali percobaan. Kesimpulan dalam penelitian ini yaitu ekstrak daun jarak kepyar tidak menimbulkan efek mortalitas pada ikan guppy. Dengue Hemorrhagic Fever (DHF) is still a significant health problem, including in Indonesia. The castor plant has been known to have larvicidal properties against aedes mosquito larvae in several studies, but a study is needed on the effect of residual effects of castor leaf larvicidal to evaluate potential risks and long-term effects and review of castor leaf extract on non-target organisms. Research method: castor leaf extract larvicidal was carried out using the maceration method. The manufacture of castor leaf extract used 4 different types of solvents. Castor leaf material was divided into two, namely young leaves and old leaves. the effect on non-target organisms was observed until the 7th day after treatment. The results showed that the effect of castor leaf extract (using 4 solvents) both young leaves and old leaves on non-target organisms (guppy fish) did not cause mortality in fish during 3 trials. The conclusion in this study is that castor leaf extract does not cause mortality in guppy fish.
Non-adherence to medication, malaria relapse, and asymptomatic reservoirs in malaria transmission: A narrative review Sahiddin, Muhamad; Ishak, Hasanuddin; Arsin, Andi Arsunan; Mallongi, Anwar; Arsyad, Muhammad; Hamid, Firdaus
Public Health of Indonesia Vol. 11 No. 4 (2025): October - December
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v11i4.1032

Abstract

Background: Malaria elimination remains a pressing global health priority, yet progress is hindered by interconnected human-driven factors that sustain residual transmission. Objectives: This review aims to integrate and analyze key factors driving residual malaria transmission, particularly non-adherence to anti-malarial medication, relapse of Plasmodium vivax and P. falciparum infections, and the persistence of asymptomatic parasite reservoirs. Methods: A narrative review was conducted by synthesizing findings from peer-reviewed studies, including observational studies, clinical trials, and program evaluations. Relevant articles were identified through PubMed, Scopus, Google Scholar, and Web of Science databases. Results: Demographic, behavioral, and health system factors were consistently associated with incomplete treatment, which in turn doubled relapse risk and extended the duration of gametocyte carriage. Biological factors, such as dormant hypnozoites and CYP2D6 polymorphisms that reduce primaquine metabolism, increased the likelihood of recurrent infections. Additionally, asymptomatic carriers disproportionately younger and mobile populations sustained transmission beyond the reach of routine surveillance. Unlike previous reviews that examined these factors separately, this review integrates them into a unified framework, emphasizing their synergistic effects on residual transmission and identifying leverage points for targeted interventions. Conclusion: Addressing residual malaria transmission requires coordinated strategies, including community-supervised or directly observed radical cure regimens, genotype-informed dosing strategies, molecular surveillance for asymptomatic infections, and culturally tailored adherence support. These interventions are essential to strengthen malaria elimination programs and advance progress toward national and global goals by 2030. Keywords: adherence medication; relapse; transmission; endemic; malaria
Co-Authors Arsin, Arsunan A. Arsunan Arsin Andi Arsunan Arsin Anwar Mallongi Arman Arman Arsin, Andi A. Bintara, Agus Dicky Alamsyah, Dicky Dwicahya, Bambang Gemini Alam Habo, Hasriwiani Hamid, Firdaus Harnia, Harnia Irawati Irawati Isra Wahid Kasman Kasman Muhammad Arsyad Muhammad Ikhtiar Poedji Hastutiek Pramestiyani, Mustika Ridha, Muhammad R. Ridwan Amiruddin Sahiddin, Muhamad Sudirman Nasir Syamsuar Manyullei