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All Journal METAMORFOSA Journal of Biological Sciences E-Jurnal Medika Udayana Jurnal Veteriner Indonesian Andrology and Biomedical Journal Jurnal Kedokteran Hewan
Jaqueline Sudiman
Obstetrics And Gynaecology Department, Udayana University, Denpasar, Bali, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Veterinary

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THE EFFECT OF COGON GRASS ROOT ETHANOL EXTRACT ON REPRODUCTIVE ORGAN AND EPIDIDYMAL SPERM QUALITY OF MOUSE WITH DIFFERENT AGES Jaqueline Sudiman; Rini Widyastuti; Alkaustariyah Lubis; Tyagita Hartady; Mas Rizky Anggun Adipurna Syamsunarno; Sony Heru Sumarsono
Jurnal Kedokteran Hewan Vol 14, No 1 (2020): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (425.204 KB) | DOI: 10.21157/j.ked.hewan.v14i1.14969

Abstract

This study aims to determine changes related to epididymal sperm parameters in mice given cogon grass root ethanol extract (CGREE). The experiment was carried out by dividing three groups of mice aged 4-week old (early pubertal), 8-week old (adult), and 24-week old (old) as control and treatment groups. The treatment groups were given 115 mg/kg body weight of CGREE for 14 days. The mice were sacrificed on day 15 to asses reproductive organ indexes and quality of the epididymal sperm. Index of epididymis and ductus deferens indices significantly reduced in the 4-week old treatment group compared to control (0.23 vs 0.33; 0.08 vs 0.16,  respectively), and vesical seminal significantly reduced in 8- week old treatment group compared to control (0.76  vs  0.68). The epididymal sperm quality significantly decreased in all treatment groups, but the sperm concentration in early pubertal group showed an increase. These results indicate that CGREE can enhance several semen parameters in prepubertal and adult mice but this effect is not apparent in old mice.
The Association of E-Cigarettes with Hypogonadism in Adult Men in Denpasar Djuanda, Louis Felix; I Gusti Ngurah Pramesemara; I Made Oka Negara; Jaqueline Sudiman; Faisal Yusuf Azhari
Indonesian Andrology and Biomedical Journal Vol. 5 No. 2 (2024): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v5i2.65652

Abstract

Background : A decrease in testosterone level can cause a set of symptoms forming a clinical syndrome called hypogonadism. One of the factors that is known to disrupt testosterone levels is smoking habits. Currently, the use of e-cigarettes as an alternative product to conventional cigarettes is increasing rapidly in many countries, including Indonesia. The amounts of harmful substances in e-cigarette aerosols are similar to the smoke produced by conventional cigarettes, but the health hazards of e-cigarettes are still not well known. Objective : This study was conducted to determine the relationship between e-cigarettes and hypogonadism in adult men in the city of Denpasar. Method: This study uses a descriptive-analytical method in the form of a cross-sectional study. The research sample consisted of 49 e-cigarette users collected using consecutive sampling techniques. The data were then analyzed using SPSS® version 26. Results : Based on the research obtained from the ADAM score from a total of 49 samples, the prevalence of hypogonadism is higher in the group of people who smoked e-cigarettes, about 35,3%. Overall, this study found a fairly high prevalence of hypogonadism (26.5%) in Denpasar. The chi-square test shows a p-value of 0,032 and a prevalence ratio (PR) of 5.294. Conclusions : Active use of e-cigarettes showed a significant association with the incidence of hypogonadism experienced by adult men in Denpasar. Based on the PR calculation, the risk of hypogonadism in active e-cigarette users was 5.294 times higher than that of adult men who were not active e-cigarette users.
Co-Authors Alkaustariyah Lubis Alkaustariyah Lubis Benedicta Audrey Maharani Djuanda, Louis Felix Endang Sri Widiyanti Faisal Yusuf Azhari Fasha Syawalia Heryaningtyas I Gusti Ngurah Pramesemara I Nyoman Gede Budiana I Wayan Artana Putra IB Putra Adnyana Ida Bagus Gde Fajar Manuaba Made Oka Negara Madeline Priscilla Mas Rizky A.A. Syamsunarno Ngurah Intan Wiratmini Ni Kadek Ari Chintya Vedantari Ni Kadek Chindy Sarindra Bhavani Ni Putu Pramana Saras Utami Ni Putu Sri Risa Dewi Ni Putu Yoni Prastini Kaesasih Nyoman Bayu Mahendra Rini Widyastuti Sony Heru Sumarsono Sony Heru Sumarsono Sony Heru Sumarsono Tjokorda Gde Agung Suwardewa Tjokorda Istri Putri Adhyasari Wulandari Tyagita Hartady Tyagita Tyagita