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Prevalence And Pattern Sensitivity Multidrug Antibiotics Resistant Pseudomonas aeruginosa in the High Care Unit at Dr. Soetomo General Academic Hospital Period 2022-2023 Kusumawati, Ratna; Koendhori, Eko Budi; Mertaniasih, Ni Made; Ikhwani, Irfan Arif; Hidayat, Dimas Firman; Levani, Yelvi; Paramitha, Ayu Lidya
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.22152

Abstract

The prevalence of Multidrug antibiotic-resistant Pseudomonas aeruginosa (MDRPA) has been increasing during the decade And has become attention in hospital patients. This retrospective descriptive descriptive aimed to determine the prevalence of MDRPA and its sensitivity patterns. Data were taken from results of bacterial culture and antibiotic resistance tests from various clinical specimens from patients at Dr. Soetomo General Academic Hospital throughout 2022-2023. The resistance test was carried out using a Vitek 2 compact instrument. MDRPA is defined as Pseudomonas aeruginosa that is not sensitive to three or more of the following classes of antibiotics: meropenem or imipenem, ciprofloxacin, gentamicin or amikacin, ceftazidime or cefepime, and piperacillin/ tazobactam. The prevalence of MDRPA was 57.0%. MDRPA isolates were also the most common origin from the burn unit and HCU A (high care unit A), mostly from pus specimens and sputum. Pseudomonas aeruginosa sensitivity was best with piperacillin/tazobactam (55.5%), meropenem (54.8%), amikacin (47.5%), gentamicin (46.5%), cefepime (46.3%), ceftazidime (45.0%), ciprofloxacin (44.7%) and aztreonam (43.2%). The sensitivity of MDRPA to antibiotics is much lower than that of Pseudomonas aeruginosa. This study showed high number of MDRPA specifically in Surabaya and the pattern sensitivity of Pseudomonas aeruginosa can become guidelines in choosing antibiotics treatment for patients.
Effect of Freeze-Drying, Spray-Drying, and Foam-Mat-Drying Encapsulation Techniques on Vitamin C Level in Fruit Powder: A Scoping Review Baruroh, Durotul; Suselo, Yuliana Heri; Kusumawati, Ratna; Dono Indarto
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.586

Abstract

Vitamin C is an essential micronutrient with important antioxidant and physiological roles. However, it is highly unstable during processing due to its sensitivity to heat, oxygen, and light. This scoping review mapped evidence on drying-based encapsulation techniques: freeze drying, spray drying, and foam-mat drying. It examines their effect on the vitamin C level in fruit powder. A systematic search was conducted in PubMed, ScienceDirect, Springer, MDPI, and Google Scholar for studies published between 2015 and 2025. The search followed the PRISMA-ScR framework. Seven studies met the criteria and covered acerola, camu-camu, banana, açaí, papaya, satsuma mandarin, orange peel, and mulberry. The findings show that freeze-drying was consistently the most effective technique for retaining vitamin C levels. Some studies even reported an increase in vitamin C levels, possibly due to the breakdown of the fruit matrix, which made the nutrient more available. During Spray drying, low retention values (11%) were obtained in banana paste, and almost total retention (99%) was achieved in camu-camu pulp. The retention of mulberry juice during optimized foam-mat drying amounted to a maximum level of 90%. Coating materials, such as gum Arabic (GA) and carboxymethyl cellulose (CMC), provided better stability in vitamin C levels. However, there are some gaps regarding encapsulation efficiency, degradation kinetics, and particular mechanisms of the matrix that could clarify retention rates beyond 100%. Thus, future studies should focus on these parameters for the refinement of scalable yet low-cost drying strategies of functional fruit powders.
Edukasi Pencegahan dan Deteksi Dini Penyakit Kardiovaskular di Masa Pandemi COVID-19 Kusumawati, Ratna; Sulastomo, Heru; Indarto, Dono; Jusup, Sinu Andhi; Rahardjo, Setyo Sri; Purwaningtyas, Niniek; Susilawati, Tri Nugraha; Suselo, Yuliana Heri; Wulandari, Sri
Smart Society Empowerment Journal Vol 3, No 1 (2023): Maret
Publisher : Faculty of Medicine, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/ssej.v3i1.70327

Abstract

Pendahuluan: Jumlah kasus penyakit kardiovaskular (PKV) di dunia menunjukkan kecenderungan meningkat termasuk di Indonesia. Kabupaten Sukoharjo di Jawa Tengah melaporkan adanya peningkatan penyakit hipertensi dan diabetes mellitus (DM) yang menjadi faktor risiko penting PKV. Penyakit hipertensi dan DM merupakan penyakit penyerta utama pada kasus coronavirus disease 2019 (COVID-19) sehingga dapat memperburuk gejala dan menyebabkan kematian. Tujuan dari kegiatan pengabdian ini adalah memberikan edukasi tentang pencegahan dan deteksi dini PKV di wilayah Kecamatan Kartasura, Sukoharjo, Jawa Tengah di masa pandemi COVID-19.Metode: Kegiatan pengabdian dilaksanakan di RT 03 RW 02 desa Gowongan, Pucangan, Kartasura, Sukoharjo, Jawa Tengah. Metode pengabdian yang dilakukan berupa pelatihan pengukuran denyut nadi latihan, talk show  mengenai pencegahan dan deteksi dini PKV serta pemeriksaan kesehatan berupa pemeriksaan tekanan darah dan kadar gula darah.Hasil dan pembahasan: Hasil kegiatan pengabdian ini peserta mendapatkan informasi yang valid mengenai pencegahan dan deteksi dini PKV. Selain itu, kegiatan ini menstimulasi keperdulian peserta untuk melakukan upaya pencegahan dan deteksi dini melalui pemeriksaan tekanan darah dan kadar gula darah. Hasil lain yang didapatkan adalah peserta dapat melakukan pengukuran denyut nadi latihan secara mandiri untuk mengoptimalkan olahraga yang dilakukan.Kesimpulan: Edukasi pencegahan dan deteksi dini PKV kepada masyarakat talkshow, pelatihan dan layanan kesehatan telah terlaksana dengan baik. Kegiatan ini dapat memberikan informasi valid kepada masyarakat dan memacu keperdulian masyarakat untuk melakukan upaya pencegahan dan deteksi dini PKV.
Edukasi dan Pemeriksaan Kesehatan Anggota Klub Jantung Sehat Rahardjo, Setyo Sri; Jusup, Sinu Andhi; Indarto, Dono; Wulandari, Sri; Suselo, Yuliana Heri; Kusumawati, Ratna; Sulastomo, Heru; Purwaningtyas, Niniek; Susilawati, Tri Nugraha
Journal of Midwifery in Community Vol 1, No 2 (2023): Oktober
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jmc.v1i2.79502

Abstract

Data Riset Kesehatan Dasar (Riskesdas) di Indonesia secara nasional memperlihatkan bahwa penyakit tidak menular (PTM) terutama penyakit kardiovaskular (PKV) cenderung mengalami peningkatan. Hal tersebut terjadi juga di wilayah kota Surakarta. Tim Pengabdi berinisiatif melaksanakan kegiatan edukasi dan pemeriksaan kesehatan yang bertujuan untuk meningkatkan pengetahuan anggota Klub Jantung Sehat (KJS) terkait PKV sekaligus untuk skrining faktor risiko PKV yang meliputi hipertensi, hiperkolesterol, diabetes mellitus (DM), dan obesitas. Metode yang digunakan berupa penyuluhan dan pemeriksaan tekanan darah, gula darah sewaktu, kolesterol dan antropometri. Kegiatan pengabdian masyarakat ini diikuti oleh 85 anggota KJS dan diselenggarakan pada hari Minggu, 18 Juni 2023 jam 07.00 - 09.00 di Fakultas Keolahragaan Universitas Sebelas Maret (FKOR UNS) Jl. Menteri Supeno, Manahan, Banjarsari Kota Surakarta Jawa Tengah. Dari kegiatan pengabdian masyarakat ini pemahaman para anggota KJS terkait PKV melalui diskusi dan tanya jawab selama penyuluhan dan konseling selama pemeriksaan kesehatan mengalami peningkatan. Kegiatan sejenis perlu dilakukan secara rutin dan berkesinambungan sebagai upaya preventif dan promotif terhadap penyakit tidak menular di masyarakat.
Edukasi dan Deteksi Dini Penyakit Diabetes Melitus Susilawati, Tri Nugraha; Jusup, Sinu Andhi; Rahardjo, Setyo Sri; Indarto, Dono; Wulandari, Sri; Suselo, Yuliana Heri; Kusumawati, Ratna; Sulastomo, Heru; Purwaningtyas, Niniek
Journal of Midwifery in Community Vol 2, No 2 (2024): Oktober
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jmc.v2i1.93242

Abstract

Indonesia currently is experiencing a shift in disease patterns marked by a significant increase in the number of non-communicable diseases (NCDs), especially cardiovascular diseases, specifically diabetes mellitus (DM). A similar phenomenon also occurs in Surakarta city. Community service team conducts educational activities and health checks that aim to increase the knowledge of members of the Klub Jantung Sehat (KJS) related to cardiovascular disease as well as for screening risk factors for cardiovascular diseases including hypertension, hyperuricemia, diabetes mellitus (DM), and obesity. The methods used are counseling and checking blood pressure, uric acid, blood sugar at any time, and anthropometry. This community service activity was attended by 33 KJS members and was held on Sunday, 23 June 2024 at 07.00 - 09.00 at the Faculty of Sports, Sebelas Maret University (FKOR UNS) Jl. Menteri Supeno, Manahan, Banjarsari, Surakarta City, Central Java, however only 19 participants took part in the complete screening. The results achieved from this community service are an increase in the knowledge of KJS members related to cardiovascular diseases through discussions during counseling as well as during health checkups. The results of the health examination, it was found that 6 people (31.58%) had hypertension, 2 people (10.52%) had DM, and 11 people (57.89%) were found to meet the criteria of overweight and obesity. The members of KJS who had uric acid levels above normal were 10 people (52.63%). Similar activities should be carried out regularly and continuously as a preventive and promotive effort against non-communicable diseases in the community.