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All Journal Jurnal Kesehatan Andalas INDONESIAN JOURNAL OF PHARMACY Universa Medicina Acta Biochimica Indonesiana Majalah Kedokteran Andalas Sumatera Medical Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Scientific Journal Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Pengabdian Masyarakat Kesehatan (JURABDIKES) Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD)
Dinda Aprilia
Fakultas Kedokteran Universitas Andalas
Humanities Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Pituitary Macroadenoma with Hypogonadism in 30 year old Liver Cirrhosis Patient: A Case Report Alexander Kam; Dinda Aprilia; Eva Decroli; Syafril Syahbuddin
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolism and Diabetes Vol. 2 No. 1 (2025): InaJEMD Vol. 2, No. 1
Publisher : PP PERKENI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66266/inajemd.v2i1.46

Abstract

Pituitary macroadenomas can suppress pituitary hormone secretion, one of which is the gonadotropin hormone, causing hypogonadism. The condition of hypogonadism can increase the risk of NAFLD, which can then become liver cirrhosis. A 30-year-old man came to the hospital with decreased consciousness and hematemesis melena. From physical examination, laboratory, and pituitary MRI, the patient was diagnosed with pituitary macroadenoma, hypogonadotropic hypogonadism, primary hypothyroidism, acute adrenal insufficiency, and liver cirrhosis. The patient was given hydrocortisone therapy, correction of electrolyte levels, hypoglycemia protocol, levothyroxine 100 mg/day, and management of hematemesis melena. After that, Sustanon 250 mg was given every two weeks intramuscularly. The patient went home in good condition and was planned for neurosurgery consultation for transsphenoidal resection. After the injection of Sustanon, the patient experienced increased penile length and testicular volume. The condition of hypogonadism in patients with pituitary macroadenoma can be a risk factor for NAFLD, which can then progress to liver cirrhosis. NAFLD and liver cirrhosis also can cause hypogonadism in men by several mechanisms. The patient has been well-managed and experienced clinical improvement.
Co-Authors Alexander Kam Annisa Pratiwi Athari Fadhila Namanda Putri Athari Fadhila Namanda Putri Auliangi Tamayo Dina Arfiani Rusjdi Dwitya Elvira, Dwitya Eka Nofita Eti Yerizel Eva Decroli Eva Decroli Fadrian Fadrian, Fadrian Harun Harnavi Hirowati Ali Husna Yetti Irfan Fadilah Jonggara Oktaviandra Siahaan Lukman Nurhakim Mohamad Reza Munsyi Nares Wari Naufal Fathi Ashari Putri Deas Hadilofyani Robby Satria Putra Rozi Abdullah Rudy Afriant Russilawati SM Rezvi Suci Berlian Hemilton Syafril Syahbuddin Syafril Syahbuddin Wahyu Agnata Surya Wati, Westi Permata Yanne Pradwi Efendi Yanne Pradwi Efendi Yanne Pradwi Efendi Yustini Alioes Zhira Shada Athaya