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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Althea Medical Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Berkala Kedokteran Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Respiratory Science
Haryati Haryati
Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine Lambung Mangkurat University, Ulin Regional Hospital, Banjarmasin
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Respiratory Science

 1 
Cholesterol Level in Covid-19 Patients Related to Severity and Mortality: A Case Series and Literature Review Anggarda Kristianti Utomo; Haryati Haryati
Respiratory Science Vol. 2 No. 1 (2021): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i1.28

Abstract

Coronavirus Disease 2019 (COVID-19) is a communicable disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).  December 2019 in Wuhan, China, is the time and place where the first pneumonia case which SARS-CoV-2 causes was found, and WHO designated COVID-19 as a pandemic by March 2020. There are reported cases of dyslipidemia associated with SARS patients, albeit rare. Several case reports showed lower cholesterol levels compared to healthy subjects. Therefore, some argued that dyslipidemia could occur in COVID-19. Several studies have revealed that hypolipidemia is positively correlated with the severity of COVID-19. In Ulin Regional Hospital Banjarmasin, several cases found higher cholesterol levels in asymptomatic and mild-moderate COVID—19 survivor compared to patients with severe/critical COVID-19and non-survivor. Two patients in the non-survivor group showed a significant decrease in cholesterol level compared to baseline, and five patients had <150 mg/dL cholesterol level during the examination. Four mild-moderate COVID-19 survivors had cholesterol levels that were greater than 150 mg/dL at the first examination and did not decrease during the evaluation. Cholesterol is thought to play an important role in the pathological development of COVID-19, and it is associated with severity and mortality, which requires further studies.
Chemotherapy in Lung Cancer With Hepatic and Renal Impairment Aida Hastuti; Erna Kusumawardhani; Haryati Haryati
Respiratory Science Vol. 2 No. 2 (2022): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v2i2.42

Abstract

Chemotherapy is one of the therapeutic modalities for lung cancer. Chemotherapy with anticancer drugs has a narrow therapeutic index and pharmacokinetic variability between individuals. The administration of anticancer drugs should consider many factors that may affect the pharmacokinetics of the drug, such as hepatic and renal function. In lung cancer patients who have hepatic and renal impairment, an adjusted dose of anticancer drug is needed to achieve levels of drug exposure similar to patients who have normal organ function and avoid toxicity. Renal function is calculated by the glomerular filtration rate or creatinine clearance. Assessment of hepatic function can be taken from Child Pugh's score or from bilirubin and aminotransferase enzyme data in patients. In addition, hepatitis screening is also required. The results of the assessment will determine the adjustment dose recommendation for anticancer drugs.
Management of Febrile Neutropenia in Lung Cancer Haryati Haryati; Nida Amalia
Respiratory Science Vol. 3 No. 2 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v3i2.72

Abstract

Febrile neutropenia (FN) is defined as an oral temperature of >38.3° C or two consecutive measures >38°C within 2 hours accompanied by an absolute neutrophil count (ANC) of 500/L or a predicted decrease below 500/L in individuals undergoing systemic chemotherapy for cancer. FN is one of the oncological emergencies that can influence cancer patients' outcomes since it can increase morbidity, treatment delays, decrease survival, and expand costs. The incidence of FN is 3.7-28% in lung cancer patients. Mortality associated with FN episodes is 15%. FN risk factors include chemotherapy regimen, age, comorbidities, mucositis, performance status, and previous FN history. Validated predicted instruments such as The Multinational Association for Supportive Care in Cancer (MASCC) or The Clinical Index of Stable Febrile Neutropenia (CISNE) score could assist in the risk assessment of FN and determine advanced management. Effective therapy of FN requires investigation of diagnosis as soon as possible and acknowledging the potential source of infection. The prophylactic granulocyte colony-stimulating factors (G-CSF) and anti-microbial successfully reduced mortality due to FN.
The Solitary Pulmonary Nodule: Is It Benign or Malignant? Haryati Haryati; Dimas Satrio Baringgo
Respiratory Science Vol. 4 No. 1 (2023): Respiratory Science
Publisher : Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/respirsci.v4i1.101

Abstract

Solitary pulmonary nodules (SPN) are round-shaped opacities with or without firm borders and ≤3 cm in diameter. 40% of solitary pulmonary nodules in high-risk populations are malignant and >10 mm in diameter. With the high incidence of pulmonary cancer, diagnosing pulmonary nodules is essential for clinicians. This review aims to discuss more solitary pulmonary nodules based on multiple recommendations for diagnosis and management. Malignancy probability assessment is the first step in evaluating each patient with new pulmonary nodules, as it significantly affects the prognosis of the disease. The assessment depends on the risk factors present in the patient, which are cigarettes, age, history of cancer, and family history. Radiological evaluation is the second phase in pulmonary nodule evaluation. Predictors of malignant nodules that should be assessed are nodule size, growth rate, nodule morphology, location, and enhancement. Many guidelines have been published regarding treating solitary pulmonary nodules, including the Fleischner Society, ACCP, and BTS guidelines. 
Co-Authors Aida Hastuti Ali Assagaf Ana Rima Andreas Infianto Anggarda Kristianti Utomo Anisa Anisa Arganita, Fidya Rahmadhany Arif Santoso Ayudiah Puspita Mayasari Ayudiah Puspita Mayasari Brian Pramana Santoso Desi Rahmawaty Desi Rahmawaty Desi Rahmawaty Dimas Satrio Baringgo Eko Suhartono Eko Suhartono Eko Suhartono Elisna Syahruddin Elok Hikmatun Nikmah Emmi Erliyanti Ermayanti, Sabrina Erna Kusumawardhani Farida Heriyani Ferry Dwi Kurniawan Fidya Rahmadhany Arganita Holly Diany Ida Ayu Jasminarti Ira Nurrasyidah Joharman Joharman Laksmi Wulandari Marsheilla Riska Mohamad Isa Muhammad Nor Nathaniel Aditya Nida Amalia Noni Novisari Soeroso Noor Athiyya Sabrina Wahda Utami Setyawan, Ungky Agus Sita Andarini Sri Melati Munir Tenri Ashari Wanahari Widya Ramadhaniati Zaini, Jamal