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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Althea Medical Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan Berkala Kedokteran Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Jurnal Ners Respiratory Science Jurnal Indonesia Sosial Teknologi
Haryati Haryati
Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine Lambung Mangkurat University, Ulin Regional Hospital, Banjarmasin
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Berkala Kedokteran

 1 
Platelet-to-Lymphocyte Ratio (PLR) Profile and Neutrophil-to-Lymphocyte Ratio (NLR) in Lung Cancer Patients in Ulin General Hospital Banjarmasin 2017-2018 Haryati Haryati; Holly Diany
Berkala Kedokteran Vol 16, No 1 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (266.654 KB) | DOI: 10.20527/jbk.v16i1.8101

Abstract

Abstract: Lung cancer is the leading cause of malignancy in the world reaching up to 13% of all cancer diagnoses. Platelet-to-Lymphocyte Ratio (PLR) and Neutrophil-to-Lymphocyte Ratio (NLR), are promising markers of inflammatory prognosis, clinical decisions for proper management of lung cancer patients. The research used a retrospective analytic observational study as its research method. Samples were taken from Pathology Anatomy Laboratory, and the medical record data of lung cancer patients in Ulin General Hospital Banjarmasin from 2017 to 2018. Male lung cancer patients have percentage of 72% with PLR NLR values by sex are not much different p>0.05. 23% of patients were aged ≥ 65 years and 77% were aged £ 65 years with value p>0.05. Adenocarcinoma reaches 65% with p>0.05. Most metastases are 44% pleural effusion with value p>0.05. Percentage of advanced stage is 90% with a higher PLR NLR value at the end stage. There is a meaningful relationship of NLR with lung cancer stage p<0.05, but no relantionship with PLR p>0.05. PRL and NRL are increased at advanced stage. NRL and PRL did not differ significantly based on age, sex and histology of lung cancer. Keywords: Platelet-to-lympho­cyte ratio (PLR), Neutrophil-to-lymphocyte ratio (NLR), lung cancer
Stage 4 Lung Cancer with Brain and Pericardial Metastases Which Are First Considered as Pulmonary Tuberculosis Infection and Heart Failure Haryati Haryati; Marsheilla Riska
Berkala Kedokteran Vol 16, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.204 KB) | DOI: 10.20527/jbk.v16i2.9226

Abstract

Abstract: Lung cancer and pulmonary tuberculosis become a global problem in the world. The similarities of clinical symptoms and radiological appearances often complicates diagnosis especially in TB endemic countries. A 43-year-old man presented with shortness of breath for 6 months, accompanied by intermittent cough mixed with blood streaks. He had been taking anti-tuberculosis for 2 months, but there’s no improvement. On physical examination, ronchi were heard in the lower 2/3 of the right lung and heart sounds diminished. Motoric movement of the left hand was difficult to grasp hard. A contrast-enhanced CT scan of the head revealed hyperdense multiple nodules. Chest X-ray showed cardiomegaly with right lung consolidation and a primary malignant right lung mass accompanied by pericardial effusion at thoracic CT scan. Cytology and EGFR examination of pericardial effusion found adenocarcinoma metastasis with exon 18 and 21 mutations. Evaluation of clinical symptoms and radiological examination during tyrosine kinase inhibitor (TKI) therapy showed improvement. Lung cancer can resemble pulmonary tuberculosis in various manifestations. Adenocarcinoma with positive EGFR mutations is more commonly found in Asians. Cytology and EGFR examination of pericardial effusion became the basis of diagnosis in this case. He was given TKI therapy. Re-evaluation must be carried out in patients who do not improve with antibiotics or anti-tuberculosis. Patient reported a good response after consuming EGFR-TKI. Keywords: lung cancer, tuberculosis, tyrosine kinase inhibitors
Co-Authors Aida Hastuti Ali Assagaf Ali Assagaf Ana Rima Andreas Infianto Anggarda Kristianti Utomo Anisa Anisa Arganita, Fidya Rahmadhany Arif Santoso Ayudiah Puspita Mayasari Ayudiah Puspita Mayasari Brian Pramana Santoso Desi Rahmawaty Desi Rahmawaty Desi Rahmawaty Dimas Satrio Baringgo Dwi Laksono Adi Putro Eko Suhartono Eko Suhartono Eko Suhartono Elisna Syahruddin Elok Hikmatun Nikmah Emmi Erliyanti Ermayanti, Sabrina Erna Kusumawardhani Farida Heriyani Ferry Dwi Kurniawan Ferryansyah Ferryansyah Fidya Rahmadhany Arganita Gusti Muhammad Perdana Putera Hapsari Lintang Sekartaji Holly Diany Ida Ayu Jasminarti Ira Nurrasyidah Iskandar Iskandar Joharman Joharman Juhairina Juhairina Laksmi Wulandari Marsheilla Riska Moh. Isa Mohamad Isa Muhammad Nor Nathaniel Aditya Nida Amalia Nila Nirmalasari Noni Novisari Soeroso Noor Athiyya Sabrina Wahda Utami Setyawan, Ungky Agus Sita Andarini Sri Melati Munir Tenri Ashari Wanahari Widya Ramadhaniati Widya Ramadhaniati Zaini, Jamal