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All Journal Jurnal Gizi dan Pangan SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN JURNAL GIZI INDONESIA Jurnal Kedokteran Diponegoro Jurnal Sain Peternakan Indonesia Indonesian Journal of Human Nutrition Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan IJEMS (Indonesian Journal of Environmental Management and Sustainability) Journal of Applied Food Technology Amerta Nutrition Medica Hospitalia
Endang Mahati
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Energy Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary Other

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Journal : Medica Hospitalia

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Correlation Between Body Mass Index, Gender, and Age With Cholelithiasis : Correlation Between Body Mass Index, Gender, and Age With Cholelithiasis Al Atsariyah, Fatimah; Parish Budiono, Bernardus; Mahati, Endang; Lestari Partiningrum, Dwi
Medica Hospitalia : Journal of Clinical Medicine Vol. 9 No. 3 (2022): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v9i3.771

Abstract

BACKGROUND : Gallstones are formed due to deposit or hypersaturation of one or more of the bile components, namely cholesterol, bilirubin, bile salts, calcium, protein, fatty acids, and phospholipids. BMI, gender, and age are the factors that can trigger the formation of gallstones. In Indonesia, cholelithiasis cases have received less attention because they are often asymptomatic, making it difficult to detect and often misdiagnosed, resulting in a lack of official publication about the incidence of gallstones in Indonesia. AIM : To determine the correlation between BMI, Gender, and Age with cholelitiasis in Dr. Kariadi Hospital. METHOD : This was an observational study using cross-sectional design. Data were taken from medical records of patients in Digestive Surgery Department Dr. Kariadi Hospital from January 2018 until March 2020. A total of 100 patients were selected as subjects (50 patients with cholethiasis and 50 patienst without cholelithiasis). Pearson Chi-Square correlation was used for statistical analysis. RESULTS : Pearson Chi-Square test of BMI (p = 0.001) and Age (p = 0.041) was statistically significant for cholelithiasis risk (p < 0.05). While Gender (p = 0.224) was not statistically significant for cholelithiasis risk. CONCLUSION : There wa a significant correlation between BMI and Age with Cholelithiasis and there was no significant correlation between Gender with Cholelithiasis. KEYWORDS : Body Mass Index (BMI), Gender, Age, Cholelithiasis.
Pemberian Krim Ekstrak Moringa oleifera L. pada Tikus dengan Luka Insisi: Studi terhadap Kadar IL-1, IL-10 dan rasio IL-1:IL-10: The Application of Moringa oleifera L. Cream on Rats with Incision Wound: Study on the IL-1 Level, IL-10 Level and IL-1:IL-10 ratio Surya Utoyo, Frederick; Bahrudin, Udin; Prajoko, Yan Wisnu; Mahati, Endang; Maharani, Nani
Medica Hospitalia : Journal of Clinical Medicine Vol. 9 No. 3 (2022): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v9i3.778

Abstract

LATAR BELAKANG : Saat ini, berbagai tanaman asli Indonesia dikembangkan sebagai bahan perawatan luka untuk hasil penyembuhan yang lebih baik. Salah satunya, yaitu Moringa oleifera L., yang  merupakan tanaman asli Indonesia serta berpotensi dapat membantu penyembuhan luka  melalui regulasi jalur sitokin inflamasi, interleukin (IL)-1 dan IL-10. TUJUAN : Untuk mengetahui pengaruh pemberian ekstrak Moringa oleifera L. terhadap IL-1, IL-10, dan rasio IL-1: IL-10 di jaringan kulit, pada tikus dengan luka insisi. METODE : Penelitian ini menggunakan desain post test only controlled group dengan sampel berupa 15 tikus Wistar yang dilakukan luka insisi. Sampel dibagi menjadi 3 kelompok perlakuan: perawatan luka dengan framycetin sulphate (KP), krim ekstrak Moringa oleifera L. 15% (M), dan krim plasebo (KN). Pengukuran kadar IL-1, IL-10, dan rasio IL-1:  IL-10 dilakukan pada hari ke-10 perlakuan melalui pengambilan jaringan. HASIL :  Kadar IL-1 pada kelompok perlakuan (M) tidak berbeda bermakna dibanding KN dan KP (33,56±4,68 vs 40,92±27,32 vs 30,23±3,92 pg/mL, p=0,543). Kelompok KP memiliki IL-10 lebih tinggi dibandingkan kelompok M dan KN (113,95±9,38; 91,75±5,65 dan 94,93±2,39 pg/mL, p<0,001), dan tidak didapatkan perbedaan antara kelompok M dan KN (p=0,296). Rasio IL-1: IL-10 kelompok KP, M, dan KN tidak menunjukan perbedaan bermakna (0,27±0,05, 0,37±0,06 dan 0,44±0,30, p=0,249). KESIMPULAN: Pemberian ekstrak Moringa oleifera L. secara topikal tidak mempengaruhi kadar IL-1 dan rasio IL-1 : IL-10 di jaringan kulit tikus dengan luka insisi. Kadar IL-10 di jaringan kulit tidak berbeda dibanding kelompok kontrol negatif, serta lebih rendah dibanding kelompok framycetin sulphate. KATA KUNCI           : Luka insisi, Moringa oleifera L., perawatan luka
Co-Authors Adriyan Pramono Ahmad Syauqy Al Atsariyah, Fatimah Albertus Ari Adrianto Anjani, Gemala Ardiansyah, Revi Arviyani, Tiffany Nisa Astika Widy Utomo Bimby Irenesia Diana Nur Afifah, Diana Nur Elvina Astiningtyas Sudaryanto Etika Ratna Noer Fulyani, Faizah Hesti Triwahyu Hutami Hidayat, Syarief Thaufik Junnaeni Junnaeni Kurniawati, Erna Yovi Lestari Partiningrum, Dwi MADE ASTAWAN Maulana, Reza Achmad Mohammad Zen Rahfiludin Mufilhatul Muniroh Nafisah Nani Maharani Nani Maharani Noor Pramono Noor Wijayahadi Novit, Elmawati Nyoman Suci Widiastiti Parish Budiono, Bernardus Puji Larasati Masyitoh Putri, Sylvia Rahmi Rahmawati, Irma Sarita Rahmawati, Siti Irma Renni Yuniarti Reyhan Zuhdi Gofita Widyawigata Setyawati, Amalia Rani Shauma, Claradhita Ayu Surya Utoyo, Frederick Udadi Sadhana, Udadi Udin Bahrudin, Udin Yan Wisnu Prajoko Yan Wisnu Prajoko Yora Nindita