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All Journal Majalah Ilmiah Peternakan Media Akademika Al-Jami'ah: Journal of Islamic Studies MPI (Media Pharmaceutica Indonesiana) Jurnal Fitofarmaka Indonesia Jurnal Kolaboratif Sains Jurnal Review Pendidikan dan Pengajaran (JRPP) Jurnal Pembelajaran Pemberdayaan Masyarakat (JP2M) Jurnal Kesehatan Tambusai Dinamika Lingkungan Indonesia MPSJ
ABD. MALIK
Dosen IAIN Sulthan Thaha Saifuddin Jambi
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Antioxidant Activity Test of Sappan (Caesalpinia sappan L.) and Chinese Teak (Senna alexandrina) Extract Combination Using DPPH (1,1 Diphenyl 2 Picrylhydrazyl) Free Radicals Scavenging Method Anisa, Rianti; Naid, Tadjuddin; Malik, Abd.; Nisaa, Nur Rezky Khairun
Jurnal Fitofarmaka Indonesia Vol 10, No 3 (2023): JURNAL FITOFARMAKA INDONESIA (ENGLISH EDITION)
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v10i3.1103

Abstract

Sappan (Caesalpinia sappan L.) is applied as food and traditional medicine. Chinese teak (Senna alexandrina) is a plant from the tropics that can be developed as an antioxidant. This study was conducted to determine the antioxidant activity of the combination of Sappan and Chinese Teak by the DPPH (1,1 Diphenyl 2 Picrylhydrazyl) Free Radical Scavenging method. The extraction method used was maceration with Ethanol 96% as solvent. Determination of antioxidant levels was done quantitatively using the UV-Vis Spectrophotometer instrument at a wavelength of 514 nm. From the results of the study, the regression value obtained for the comparison of Quercetin is y = 3.1303x + 0.2292 with R2 = 0.9974 and IC50 value of 15.899 μg/mL. For the antioxidant activity of Sappan, the regression value y=0.5769x + 18.543 with R2=0.9969 and IC50 value of 54.53 μg/mL, Chinese Teak obtained regression value y=0.1421x + 17.506 with R2=0.9989 and IC50 value of 228.67 μg/mL, and for the combination obtained regression value y=0.4304x + 36.622 with R2=0.9954 and IC50 value of 40.38 μg/mL. The results of this study indicate that the combination of Sappan and Chinese Teak extracts has a very strong antioxidant effect (<50 μg/mL).
Xanthine Oxidase Inhibitory and Antioxidant Activities of Kasumba Turate and Secang Extracts Combination Malik, Abd.; Dahlia, Andi Amaliah; Handayani, Virsa; Widiastuti, Harti; San, Htoo Tint; Ahmad, Aktsar Roskiana
MPI (Media Pharmaceutica Indonesiana) Vol. 8 No. 1 (2026): JUNE
Publisher : Fakultas Farmasi, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24123/mpi.v8i1.8473

Abstract

Kasumba turate flower and Secang lignum have been commonly known as traditional medicinal widely grown in South Sulawesi. Both contain active constituents, including coloring agents such as carthamin in Kasumba turate and brazillin in Secang. These plants have been commonly used in traditional medicine to treat conditions such as high cholesterol, bacterial and viral infections, gout, and as antioxidants. Gout and high cholesterol are closely related. The combination of Kasumba turate and Secang extracts was intended to enhance activity. The evaluation of the xanthine oxidase inhibitor (XOD) and antioxidant activity (AO) was performed using the reducing uric acid and antioxidant FRAP methods. The XOD inhibitory study found that the extracts have activities as follow Sample A, B, C, and Allopurinol of 1.40; 2.1967; 2.24; and 1.39 μg/mL, respectively. The antioxidant capacity of Kasumba turate, Secang extract and their combination was 122.88; 17.36; and 197.31 μg/mL, respectively. We concluded that the combination did not increase the XOD inhibitory and antioxidant capacity. The Kasumba turate extract has the highest activity among the tested extracts.
Co-Authors A Amaliah Dahlia AAM GUNAWAN Agus Budianto Ahmad Najib Ahmad, Aktsar Roskiana Ainina, Adiva Nur Al Arobi, Achmad Syuro Anisa, Rianti Arrozak, Muhammad Azizi, Pedja Rifki Bagus Cahyanto Fadhilah, Putri Nur Fadliyah, Nurfadhilah Fitria, Rhizma Nur Harti Widiastuti Hasnaeni hasnaeni, Hasnaeni Hatim Gazali HM, Nur Rahmah Kusdarini, Esthi Lomba, Sepriyaco Masrukhin Masrukhin Matompo, Osgar S. Mutmainah, Syifa Nisaa, Nur Rezky Khairun Rahayu, Sitti Dian Risda Waris, Risda San, Htoo Tint SUDARMAJI SUDARMAJI Sumartono Sumartono Tadjuddin Naid Utamakno, Lakon Virsa Handayani Yulandra, Novita