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All Journal Folia Medica Indonesiana JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Majalah Obstetri dan Ginekologi INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL
Ninik Darsini
Departemen Biologi Kedokteran, Fakultas Kedokteran, Universitas Airlangga, Surabaya
Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Minuman Kedelai (Glycine max) dan Kombinasi Asam Jawa (Tamarindus indica) dengan Kunyit (Curcuma domestica) dalam Mengurangi Nyeri Haid Claudia Anggie Anugrahhayyu; Ninik Darsini; Ashon Sa'adi
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 5 No. 1 (2018): Jurnal Farmasi dan Ilmu Kefarmasian Indonesia
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.752 KB) | DOI: 10.20473/jfiki.v5i12018.1-5

Abstract

Pendahuluan: Beberapa wanita ketika mentruasi dengan nyeri perut baik sebelum menstruasi atau selama menstruasi itu disebut dismenorea. Gejala dismenorea seperti rasa sakit yang memancar ke belakang dengan durasi rasa sakit kurang lebih selama 8 hingga 72 jam. Tujuan: Penelitian ini bertujuan untuk mempelajari seberapa besar pengaruh kedelai (Glycine max) dan kombinasi asam jawa (Tamarindus indica) dengan kunyit (Curcuma domestica) dalam mengurangi skala nyeri dismenorea siswi di SMK Farmasi Sekesal Surabaya. Metode: Penelitian ini merupakan penelitian eksperimental dengan Quasy experimental pretest and posttest design. Total sampel 27 siswi termasuk usia 15 - 18 tahun sesuai dengan kriteria inklusi. Pengambilan sampel dilakukan dengan purposive sampling. Variabel bebasnya adalah asam jawa (Tamarindus indica), kunyit (Curcuma domestica), dan kedelai (Glycine max), sedangkan variabel dependennya adalah nyeri dismenorea. Mengetahui tingkat signifikan, data yang terkumpul dari total 27 responden masing-masing 9 responden pada tiap kelompok dan hasilnya akan diuji dengan uji statistik uji Wilcoxon Sign Rank Test, Kruskal Wallis Test dan Mann Whitney U Test pada taraf signifikan α = 0,05. Hasil: Hasil penelitian menunjukkan bahwa ada perbedaan bermakna pada pemberian kedelai (Glycine max) dan kombinasi asam jawa (Tamarindus indica) dengan kunyit (Curcuma domestica) terhadap skala nyeri dismenorea siswi di SMK Sekesal Surabaya. Kesimpulan: Minuman kombinasi asam jawa (Tamarindus indica) dengan kunyit (Curcuma domestica) semakin menurunkan skala nyeri dismenorea dibandingkan dengan minuman kedelai (Glycine max) pada siswa remaja di SMK Farmasi Sekesal Surabaya.
Comparison of pregnancy rates on day 3 and day 5 embryo transfer in In Vitro Fertilization (IVF) Audia Mumtaz Rifasky; Puspa Wardhani; Ashon Sa’adi; Ninik Darsini; Hamdani Lunardhi; Zakiyatul Faizah
Majalah Obstetri dan Ginekologi Vol. 29 No. 1 (2021): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V29I12021.14-17

Abstract

Objectives: To identify the success rates of pregnancy on the third and fifth day embryo transfer at Graha Amerta Hospital, Surabaya, Indonesia.Materials and Methods: This study used comparative cross sectional design. Data were taken from medical record of IVF participants who met the inclusion and exclusion criteria at Graha Amerta Hospital for the period of January 2016 - December 2016.Results: Successful pregnancy rates were found in this research. The embryo transfer on the third day and the fifth day were 35% and 49.3% respectively. In other words, the rates of pregnancy success were not affected by embryo transfer on the third day and the fifth day in the medical record sample as it had p value of 0.090.Conclusion: Embryo transfer on the third and fifth days had the same rates of pregnancy success in IVF participants at Graha Amerta Hospital, Surabaya, Indonesia. 
Human Sperm Motility, Viability, and Morphology Decreased after Cryopreservation Ninik Darsini; Berliana Hamidah; Seso Sulijaya Suyono; Faisal Yusuf Ashari; R Haryanto Aswin; Rina Yudiwati
Folia Medica Indonesiana Vol. 55 No. 3 (2019): September
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (151.624 KB) | DOI: 10.20473/fmi.v55i3.15501

Abstract

The aim of this study was to analyze human sperm motility, viability, and morphology before and after cryopreservation. This true laboratory experimental study had pre and post randomized one group design. The study was conducted at the Embryology, Andrology, and Genetics Laboratory, Department of Medical Biology, Faculty of Medicine, Universitas Airlangga from August to November 2017. The eighteen samples of fresh semen were collected from male volunteers who agreed and signed the informed consent of the study. Samples were analyzed their motility, viability, and morphology before and after cryopreservation. Results of this study indicated differentiation between motility before and after cryopreservation. Cryopreservation process decreased progressive motility (42.22 + 9.46%; 17.83 + 6.24%; p< 0.0001) and increased the number of immotile spermatozoa (35.44 + 10.15%; 60.11 + 12.53%; p< 0.0001). Cryopreservation also decreased human sperm viability (73.78 + 8.91%; 40.83 + 12.89%; p< 0.0001) and morphology (10.94 + 4.96%; 7.39 + 3.90%; p< 0.0001). Cryopreservation of human spermatozoa caused the decreased of motility, viability, and morphology.
FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN PERSALINAN PREMATUR DI RSUD DR SOETOMO Noza Loviana; Ninik Darsini; Aditiawarman Aditiawarman
Indonesian Midwifery and Health Sciences Journal Vol. 3 No. 1 (2019): Indonesian Midwifery and Health Sciences Journal, January 2019
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v3i1.2019.85-97

Abstract

AbstrakLatar Belakang: Secara global, persalinan preterm menjadi penyebab utama kematian neonatus usia dini 0-7 hari pertama kehidupan dengan menimbulkan dampak morbiditas yang tinggi juga. Indonesia menempati urutan negara ke 5 estimasi persalinan preterm tertinggi di dunia. Beberapa faktor yang dapat berpengaruh terhadap persalinan preterm yaitu idiopatik, iatrogenik, sosio-demografi, maternal dan genetik. Penelitian ini bertujuan untuk melihat hubungan antara usia ibu, pendidikan ibu, pekerjaan ibu dan riwayat persalinan preterm terhadap kejadian persalinan prterm di RSUD Dr. Soetomo Surabaya. Metode: Metode penelitian ini adalah analitik observasional dengan rancang bangun case control. Jumlah populasi sebanyak 1311 orang pada periode 1 Januari - 31 Desember 2018. Sampel dibagi dalam dua kelompok yaitu kelompok kasus (ibu yang bersalin preterm) dan kelompok kontrol (ibu yang bersalin tidak preterm) sebanyak masing-masing kelompok 137 orang yang disesuaikan dengan kriteria inklusi dan eksklusi dan berdasarkan teknik pengambilan sampel yaitu simpel random sampling. Variabel independen terdiri dari usia ibu, pendidikan, pekerjaan dan riwayat persalinan preterm sedangkan variabel dependen adalah persalinan preterm. Analisis data bivariat menggunankan uji Chi-Square test dengan taraf signifikansi α = 0,05 (95% CI). Hasil: Hasil uji Chi-Square menunjukkan bahwa tidak ada hubungan bermakna antara usia ibu bersalin (nilai p = 0,259), pendidikan  (nilai p = 1), pekerjaan (nilai p = 0,225) dan riwayat persalinan preterm (nilai p = 0,191) dengan kejadian persalinan preterm. Kesimpulan: Faktor risiko seperti usa ibu bersalin, pendidikan ibu, pekerjaan ibu dan riwayat persalinan preterm tidak memiliki hubungan terhadap kejadian persalinan preterm. Abtract Background : Globally, preterm labor is the main cause of neonatal mortality in the first 0-7 days of life with a high impact of morbidity. Indonesia ranks 5th in the highest estimate of preterm labor in the world. Several factors that can influence preterm labor are idiopathic, iatrogenic, socio-demographic, maternal and genetic. This study aims to look at the relationship between maternal age, maternal education, maternal occupation and a history of preterm labor against the incidence of prenatal labor in RSUD Dr. Soetomo Surabaya. Method : The method of this study is observational analytic with a case-control design. The total population is 1311 people in the period January 1 - December 31, 2018. Samples were divided into two groups, namely the case group (preterm maternity) and the control group (mothers who were not preterm) as many as 137 groups each according to the inclusion criteria and exclusion and based on sampling techniques, namely simple random sampling. Independent variables consisted of maternal age, education, occupation and a history of preterm labor while the dependent variable was preterm labor. Bivariate data analysis used the Chi-Square test with a significance level of α = 0.05 (95% CI). Results : The Chi-Square test results showed that there was no significant relationship between maternal age (p = 0.259), education (p = 1), employment (p = 0.225) and preterm labor history (p = 0.191) with the incidence of preterm labor. Conclusion: Risk factors such as maternal age, maternal education, maternal occupation and a history of preterm labor have no relationship to the incidence of preterm labor.  
GANGGUAN MENSTRUASI PADA AKSEPTOR DMPA TIDAK TERKAIT IMT Cicilia Valentine Simamora; Sri Ratna Dwiningsih; Ninik Darsini
Indonesian Midwifery and Health Sciences Journal Vol. 3 No. 3 (2019): Indonesian Midwifery and Health Sciences Journal, July 2019
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v3i3.2019.196-203

Abstract

Abstrak Latar Belakang: Kejadian akseptor drop out tertinggi karena efek samping yaitu pada metode suntikan. KB injeksi DMPA memiliki efek samping gangguan menstruasi. Untuk menjamin lancarnya menstruasi, wanita harus mempunyai kadar lemak sebanyak 22% dari berat badannya. Kadar lemak dapat ditentukan dengan menilai berat badan seseorang melalui pengukuran Indeks Massa Tubuh (IMT). Penelitian ini bertujuan untuk mempelajari hubungan IMT dengan gangguan menstruasi pada akseptor KB injeksi DMPA di Puskesmas Jagir. Metode: Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional. Jumlah sampel sebanyak 67 orang meliputi akseptor KB injeksi DMPA di Puskesmas Jagir sesuai dengan kriteria inklusi. Sampling dilakukan dengan total sampling. Variabel bebas dalam penelitian ini adalah IMT pada akseptor KB injeksi DMPA, sedangkan variabel tergantung adalah gangguan menstruasi pada akseptor KB injeksi DMPA. Untuk mengetahui tingkat signifikan, data yang terkumpul akan diuji dengan uji statistik Pearson pada tingkat kemaknaan α=0,05. Hasil: Hasil penelitian didapatkan bahwa sebagian besar responden memiliki IMT normal (55,2%), IMT kurus (3,0%) dan IMT overweight (41,8%). Hampir seluruhnya mengalami gangguan menstruasi (88,1%) dan yang tidak mengalami gangguan menstruasi (11,4%). Setelah uji Pearson diperoleh nilai p=0,140 (p>0,05) yang berarti bahwa tidak ada hubungan antara IMT dengan gangguan menstruasi pada akseptor KB injeksi DMPA. Kesimpulan: Tidak ada hubungan antara IMT dengan gangguan menstruasi pada akseptor KB injeksi DMPA di Puskesmas Jagir. Abstract Background: The incidence of drop out acceptors mostly due to side effects, is found on the injection method. DMPA injection has side effects of menstrual disorders. To ensure a fluent menstruation, women should have fat mass at least 22% of their body weight. Fat mass can be determined by measuring the Body Mass Index (BMI). This research aims to study the relationship of BMI with menstrual disorders in DMPA injection receiver at Puskesmas Jagir. Methods: This research is an observational analytic research with a cross sectional approach. A total sample of 67 people included DMPA injection receiver at Puskesmas Jagir corresponding for inclusion criteria. Sampling is done by total sampling. The independent variable in this study was BMI in DMPA injection receiver, while the dependent variable was menstrual disorders in DMPA injection receiver. To determine a significant level, the collected data will be tested by Pearson at the significance level of α = 0.05. Results: The results of the study showed that most of respondents had normal BMI (55.2%), thin BMI (3,0%) and overweight BMI (44.8%). Most of them experienced menstrual disorders (88.1%) and others did not experience menstrual disorders (11.4%). After the Pearson test, the value of p = 0.140 (p > 0.05) which means that there is no relationship between BMI and menstrual disorders in DMPA injection receiver. Conclusion: There is no relationship of BMI with menstrual disorders in DMPA injection receiver at Puskesmas Jagir.
PERBEDAAN FREKUENSI SAKIT BAYI USIA 6-12 BULAN YANG DIBERIKAN ASI EKSKLUSIF DAN NON ASI EKSKLUSIF Nadya Khuswatun Khasanani; Ninik Darsini; Dwiyanti Puspitasari
Indonesian Midwifery and Health Sciences Journal Vol. 3 No. 4 (2019): Indonesian Midwifery and Health Sciences Journal, October 2019
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v3i4.2019.293-304

Abstract

Abstrak Latar belakang : Angka Kematian Bayi (AKB) yang tinggi masih menjadi permasalahan di Indonesia. Berbagai upaya telah dilakukan untuk menurunkan angka morbiditas dan mortalitas. Salah satunya dengan pemberian ASI eksklusif. Namun, cakupan ASI eksklusif di Indonesia masih belum mencapai angka yang diharapkan. Pada tahun 2017 cakupan pemberian ASI eksklusif di Surabaya terendah berada di Kelurahan Sidotopo Wetan, yaitu sebesar 51,94%. Penelitian ini bertujuan untuk mengetahui perbedaan frekuensi sakit bayi usia 6 – 12 bulan yang diberikan ASI eksklusif dan non ASI eksklusif. Metode : Jenis penelitian analitik observasional dengan rancangan penelitian cross-sectional. Sampel sejumlah 102 ibu yang memiliki bayi usia 6 – 12 bulan ( 53 bayi ASI eksklusif dan 49 bayi non ASI eksklusif). Sampling dengan cluster sampling. Variabel dependen adalah frekuensi sakit, variabel independen adalah bayi usia 6 – 12 bulan yang diberikan ASI eksklusif dan non ASI eksklusif. Instrumen yang digunakan adalah kuesioner. Analisis data menggunakan chi square(α = 0,05). Hasil : Bayi dengan ASI eksklusif sebagian besar memiliki frekuensi sakit yang jarang (79,2%), sedangkan bayi non ASI eksklusif sebagian besar memiliki frekuensi sakit yang sering (85,7%). Hasil uji chi square( p<0,001, OR=22,9), yang berarti bahwa terdapat perbedaan frekuensi sakit pada bayi usia 6 – 12 bulan yang diberikan ASI eksklusif dan non ASI eksklusif di Kelurahan Sidotopo Wetan, Surabaya. Kesimpulan : Bayi yang diberikan ASI eksklusif memiliki frekuensi sakit lebih jarang daripada bayi yang tidak diberikan ASI eksklusif.Abstract Background: High Infant Mortality Rate (IMR) is still a problem in Indonesia. Various efforts have been made to reduce morbidity and mortality. One of them is exclusive breastfeeding. However, the coverage of exclusive breastfeeding in Indonesia still has not reached the expected rate. In 2017 the lowest coverage of exclusive breastfeeding in Surabaya was in Sidotopo Wetan Village, which was 51.94%. This study aims to determine the difference frequency of illness in infants aged 6 - 12 months are given exclusive breastfeeding and non-exclusive breastfeeding. Method: Type of observational analytic study with cross-sectional study design. A sample of 102 mothers who had infants aged 6 - 12 months ( 53 infants exclusively breastfeeding and 49 infants non-exclusive breastfeeding). Sampling with cluster sampling. The dependent variable is the frequency of illness, the independent variable is infants aged 6 - 12 months are given exclusive breastfeeding and non-exclusive breastfeeding. The instrument used was a questionnaire. Data analysis using chi square (α = 0.05). Results: Most infants with exclusive breastfeeding had a rare frequency of illness (79.2%), while most non-exclusive breastfeeding infants had frequent frequency of illness (85.7%). Result of chi square test (p<0.001, OR=22,9),  which means that there were differences frequency of illness in infants aged 6-12 months were given exclusive breastfeeding and non-exclusive breastfeeding in Sidotopo Wetan Village.Surabaya. Conclusion: Infants are given exclusive breastfeeding have a less frequency of illness than infants are not given exclusive breastfeeding.
FACTORS THAT INFLUENCING THE AWARENESS OF THE FIRST ANTENATAL VISIT Maria Magdalena Awi; Dwi Purwanti; Reny I’tishom; Ninik Darsini
Indonesian Midwifery and Health Sciences Journal Vol. 4 No. 3 (2020): Indonesian Midwifery and Health Sciences Journal, July 2020
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v4i3.2020.264-273

Abstract

ABSTRACTBackground : K1 antenatal care visits at gestational age less than 13 weeks has a very important meaning for pregnant women as well as maternal and child health programs because of their contribution to the prevention of maternal deaths. Coverage of K1 in Puskesmas Watukapu  still has a gap of 28.05%.This study aims to determine the factors that influence the K1 antenatal care visit. Methode : The research method was analytic observational with cross sectional design. The sample in this study were all pregnant women trimesters 2 and 3 who came to visit the POLI KIA Puskesmas Watukapu.The sample size of 70 respondents was taken by non-probability sampling technique with consecutive sampling.The independent variable was K1 antenatal care visit, while the dependent variable were age, knowledge, education, parity, attitude, husband's support and family support.Research instrument with questionnaire. Bivariate data analysis used chi square test and multivariate test used  multiple logistic regression  test.  Results:this study found that the proportion of K1 antenatal care visits was 62.4%. Bivariate statistical test results knowledge P = 0,000 (p <0,005), attitude P = 0,135 (P> 0,005), husband support P = 0,000 (P <0,005), family support P = 0,004 (P <0,005), age P = 0,331 (P> 0.005), education P = 0.004 (P <0.005), parity P = 0.015 (P <0.05).  Multivariate test results with  P value <0.005 was  parity with a P value of 0.017.Conclusion: There is a correlation between knowledge, education, parity, husband's support and family support to the awareness of K1 antenatal care visits with the most dominant factor is parity.  
Co-Authors Aditiawarman Aditiawarman, Aditiawarman Agustinus Agustinus Andri Rezano Ashon Sa'adi Ashon Sa’adi Aswin, R. Haryanto Aucky Hinting Audia Mumtaz Rifasky Berliana Hamidah Cicilia Valentine Simamora Claudia Anggie Anugrahhayyu Dwiyanti Puspitasari, Dwiyanti Eni Maria Sisca Faisal Yusuf Ashari Faizah, Zakiyatul Hamdani Lunardhi I'tishom, Reny Maitra Djiang Wen Maria Magdalena Awi Nadya Khuswatun Khasanani Noza Loviana Pakpahan, Cennikon Purwanti, Dwi Puspa Wardhani Ria Margiana Seso Sulijaya Suyono Sri Ratna Dwiningsih Supardi Supardi Tiara Kirana Yudiwati, Rina