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All Journal Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Interdental Jurnal Kedokteran Gigi (IJKG) Indonesian Journal of Dental Medicine Sinnun Maxillofacial Journal Bakti Nusa Linggau Enrichment: Journal of Multidisciplinary Research and Development
Nurina Febriyanti Ayuningtyas
Department Of Oral Medicine, Faculty Of Dental Medicine, Universitas Airlangga, Surabaya
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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Knowledge and perception of dental profession students about the selection of mouthwash for recurrent aphthous stomatitis (RAS) therapy Ayuningtyas, Nurina Febriyanti; Surboyo, Meircurius Dwi Condro; Nagoro, Ayu Anggraini Broto; Hendrayanto, Shalma Maulidya; Rachmadanti, Zhafira Khansa
Enrichment: Journal of Multidisciplinary Research and Development Vol. 2 No. 9 (2024): Enrichment: Journal of Multidisciplinary Research and Development
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/enrichment.v2i9.236

Abstract

Recurrent aphthous stomatitis (RAS) is a recurring ulcer on the oral mucosa with no known cause and without association with systemic diseases. Dental profession students are expected to have adequate knowledge and positive perceptions regarding the use of mouthwash for RAS therapy. This study aimed to describe the levels of knowledge and perception of dental students about the selection and use of mouthwash for managing RAS. The study involved 90 students from the Dental Profession Study Programme at the Faculty of Dental Medicine, Universitas Airlangga, Surabaya. Data were collected through an online questionnaire comprising 18 questions, divided into two categories: (1) knowledge of mouthwash brands, active ingredients, usage duration, and timing, and (2) perceptions regarding the importance, safety, and effectiveness of mouthwash for RAS. The responses were tabulated and presented in percentages. The results revealed that 95.56% of respondents demonstrated good knowledge of mouthwash for RAS therapy. Perceptions of the importance, safety, and effectiveness of mouthwash were 87.78%, 98.89%, and 94.44%, respectively, with an overall positive perception rate of 92.22%. In conclusion, dental profession students at Universitas Airlangga possess a high level of knowledge and positive perceptions about the use of mouthwash for RAS therapy.
Oral Management of Herpes-Associated Erythema Multiforme in A Microcytic Anaemia Patient Ayuningtyas , Nurina Febriyanti; Sismiyanti, Rossy; YasminMahdani, Fatma; Dewi, Gremita Kusuma
Interdental Jurnal Kedokteran Gigi (IJKG) Vol. 21 No. 2 (2025): Interdental Jurnal Kedokteran Gigi (IJKG)
Publisher : Fakultas Kedokteran Gigi, Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46862/interdental.v21i2.10897

Abstract

Introduction: One acute and self-limiting hypersensitivity reaction affecting the skin and/or other mucous membranes is known as Erythema Multiforme (EM). EM is considered to be associated with infections or medications. Infection with Herpes Simplex Virus types 1 and 2 (HSV-1 and HSV-2) is a well-known predisposing factor and the most prevalent cause of EM, also referred to as Herpes Associated Erythema Multiforme (HAEM). Case: A 31-year-old female patient presented to RSGM Universitas Airlangga with red-black crusts, erosion, and bleeding on her lips, as well as erosion and sloughing of the oral mucosa. She had experienced fever and chills for a week, and three days later, lesions appeared on the lips and oral mucosa. The symptoms progressively worsened despite treatment. Case Treatment: At the first visit, the patient was referred for serology tests, complete blood count, IgM and IgG Anti-HSV 1 and Anti-HSV 2, and total IgE. Positive serology for IgG Anti-HSV 1 confirmed the diagnosis, and microcytic anaemia was also detected. The patient was treated with steroid orabase and oral elixir, administered four times daily. Discussions: The first line in treatment management is using antiviral therapy. Early treatment with oral antivirals may lessen the number and duration of lesions. Topical steroids can be given in dosage form, paste in orabase, ointment or elixir according to the involvement of the lesion area. Conclusion: Management of HAEM must determine the etiology and symptoms. A prompt and correct diagnosis following by the right approach to oral management not only cure but also prevent recurrence and improve the quality of life.
Korelasi antara profil darah lengkap dengan waktu penyembuhan Recurrent Aphthous Stomatitis: observasional analitik Rajah, Karthiyayinee Alagir; Ayuningtyas, Nurina Febriyanti; Parmadiati, Adiastuti Endah; Radithia, Desiana; Mahdani, Fatma Yasmin; Pratiwi, Aulya Setyo; Bakti, Reiska Kumala; Dewi, Gremita Kusuma
Jurnal Kedokteran Gigi Universitas Padjadjaran Vol 37, No 2 (2025): Agustus 2025
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkg.v37i2.61016

Abstract

Pendahuluan: Recurrent Aphthous Stomatitis (RAS) merupakan salah satu penyakit pada mukosa rongga mulut yang paling sering dijumpai. RAS timbul dengan berbagai faktor predisposisi, disertai rasa nyeri, dengan waktu penyembuhan yang berbeda-beda. Tes darah lengkap adalah tes darah mengukur beberapa komponen darah termasuk sel darah merah, sel darah putih, hemoglobin, hematokrit dan trombosit. Di antara faktor etiologi RAS diketahui faktor inflamasi yang berperan. Secara teori, diketahui bahwa neutrofil dan limfosit bertanggung jawab terhadap terjadinya inflamasi. Penelitian ini bertujuan untuk menganalisis apakah terdapat korelasi antara profil hitung darah lengkap dan waktu penyembuhan RAS. Metode: Penelitian ini adalah penelitian analitik observasional dengan rancangan potong-lintang (cross-sectional). Metode pengambilan sampel dalam penelitian ini adalah total sampling. Penelitian ini menggunakan 20 pasien yang sedang mengalami RAS. Data pasien didapatkan dari rekam medik RSGM Universitas Airlangga. Data yang diambil lengkap dengan tes darah pasien serta waktu penyembuhan RAS. Data dari kedua variabel dianalisis menggunakan uji korelasi statistik. Korelasi Pearson digunakan ketika data terdistribusi secara normal sedangkan Spearman's Rho digunakan ketika data tidak terdistribusi secara normal. Hasil: Hasil uji korelasi Pearson antara limfosit dan waktu penyembuhan RAS dengan nilai r=-0,459 ; p=0,042 menunjukkan nilai korelasi negatif yang berarti semakin tinggi kadar limfosit maka semakin rendah waktu penyembuhan RAS. Limfosit, trombosit, eosinofil dan LED juga menunjukkan nilai korelasi negatif tetapi tidak signifikan karena p>0,05. Tidak ada nilai signifikan yang ditemukan pada variabel lain kecuali limfosit dan MCHC. Simpulan: terdapat korelasi antara profil darah lengkap (limfosit dan MCHC) dengan waktu penyembuhan RAS.The correlation between complete blood profile and healing time of Recurrent Aphthous Stomatitis: analytical observationalIntroduction: Recurrent Aphthous Stomatitis (RAS) is one of the most common oral mucosa diseases. RAS occurs with various predisposing factors, accompanied by pain, and has varying healing times. A complete blood count is a blood test that measures several blood components, including red blood cells, white blood cells, hemoglobin, hematocrit, and platelets. Among the etiological factors of RAS, inflammatory factors are known to play a role. In theory, it is known that neutrophils and lymphocytes are responsible for inflammation. Methods: This study is an observational analytical study with a cross-sectional design. The sampling method in this study is total sampling. This study used 20 patients who were experiencing RAS. Patient data has been obtained from the medical records of RSGM Universitas Airlangga. The data is complete, including patient blood tests and RAS healing time. Data from both variables were analyzed using statistical correlation tests. Pearson correlation is used when the data is normally distributed, while Spearman's Rho is used when the data is not normally distributed. Results: The results of the Pearson correlation test between lymphocytes and RAS healing time with a value of r = -0,459; p = 0,042 showed a negative correlation value, meaning that the higher the lymphocyte levels, the lower the RAS healing time. Lymphocytes, platelets, eosinophils, and LED also showed negative correlation values but were not significant because p>0,05. No significant values were found in other variables except lymphocytes and MCHC. Conclusion: a correlation exists between complete blood profile (lymphocytes and MCHC) and RAS healing time.
Oral field cancerization: Genetic profiling for a prevention strategy for oral potentially malignant disorders Puspasari, Karlina; Pasaribu, Togu Andrie Simon; Surboyo, Meircurius Dwi Condro; Ayuningtyas, Nurina Febriyanti; Santosh, Arvind Babu Rajendra; Ernawati, Diah Savitri
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i3.p189-196

Abstract

Background: Oral cancer therapy, such as radiation or surgical treatment, has pernicious long-term effects that patients suffer throughout their life, the disability being considerable with delayed diagnosis. It is well known that many oral cancers develop from oral potentially malignant disorders (OPMDs). Patients diagnosed with OPMDs may have an increased risk of developing cancer anywhere in the oral cavity. Early detection and intervention could be essential prevention strategies to inhibit oral cancer progression. OPMDs may not immediately develop into carcinoma. However, this condition provides a "field” of specific abnormalities wherein evolving altered genetic cells can be explained with the "field cancerization” concept. Purpose: This review aims to describe the "field cancerization” concept in oral cancer and OPMD, which is expected to contribute to a better clinical management strategy for oral cancer prevention. Review: "Oral field cancerization” describes oral cancers that develop in multifocal areas of pre-cancerous changes. It can be found as histologically abnormal tissue surrounding the tumor, suggesting that oral cancer often consists of multiple independent lesions. Conclusion: The oral field cancerization concept should prompt healthcare professionals to remind their patients that frequent oral examination with histological studies and molecular testing is mandatory for those at high risk of developing malignancies.
Co-Authors Adiastuti Endah Parmadiati Adiastuti Endah Permadiati Ari Hapsari Tri Wardani Aulya Setyo Pratiwi Bagus Soebadi Basalamah, Fatimah F. Bima Ewando Kaban Desiana Radithia, Desiana Desvia Nuzela Qurzani Hariyadi Dewi, Gremita Kusuma Diah Savitri Ernawati Fahmi Dimas Abdul Azis Fatma Yasmin Mahdani Femilian, Afryla Grahania Octaviono Mahardika Hendrayanto, Shalma Maulidya Hening Tuti Hendarti Intan Noha Brilyanti Kuntardjo, Yuhanna Lani Berlina Talahatu Nagoro, Ayu Anggraini Broto Pasaribu, Togu Andrie S. Pasaribu, Togu Andrie Simon Pramitha, Selviana R. Pramitha, Selviana Rizky Pratiwi, Aulya Setyo Puspasari, Karlina Puspitasari, Yeni Rachmadanti, Zhafira Khansa Rajah, Karthiyayinee Alagir Ratna Fitri, Adinda Reiska Kumala Bakti Retno Pudji Rahayu Retno Widyowati Rosnah Binti Zain Saka Winias Santosh, Arvind Babu Rajendra Sismiyanti, Rossy Sukmawati, Natasya Fauzia Surboyo, Meircurius Dwi Condro Syahrur Marta Dwi Susilo Tutik Sri Wahyuni Winda Dwi Malinda Masuku YasminMahdani, Fatma