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UNILATERAL CMV RETINITIS IN HIV/AIDS PATIENT WITH MULTIPLE OPPORTUNISTIC INFECTIONS: Poster Presentation - Case Report - Resident Bening, Daya Banyu; Firmansjah, Muhammad; Zuhria, Ismi; Yustiarini, Ima; Widjaja, Sauli Ari
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/4fdqtz59

Abstract

Introduction : CMV Retinitis is the most common opportunistic infection in HIV/AIDS patient. Ocular manifestations in HIV/AIDS have similar clinical features though the management therapies are different. Case Illustration : A 47-year-old man was presented with blurred vision on LE since 4 months. Patient was diagnosed with HIV/AIDS since 2 years. Patient only had light perception on LE, and 5/10 on RE. The LE anterior segment showed flare and cell indicating active anterior uveitis. The LE posterior segment revealed extensive hemorrhage and exudate known as ‘pizza pie’ appearance, and cotton wool spot with multiple ischemic areas on RE. Laboratory tests revealed reactive IgG CMV and very low CD4 count (4 cell/?l). Patient was also diagnosed with Tinea Corporis, Scabies, and Pneumocystis carinii pneumonia. Oral Valganciclovir 900 mg was administered twice a day for 3 weeks, along with anti- retroviral therapy. Discussion : The anterior uveitis and ‘pizza pie’ appearance with positive CMV IgG indicate CMV Retinitis in fulminant form. Cotton wool spot found in the RE leads to retinal microvasculopathy due to HIV invading the vascular endothelium and causing increased plasma viscosity. This patient only had 4 cell/?l CD4 which indicates severe immune deficiency. If not treated immediately, patients with CD4 count <50 are at higher risk of contralateral eye involvement. Oral Valganciclovir was chosen considering the multiple opportunistic infections the patient had. Conclusion : It is important to distinguish CMV retinitis with other HIV/AIDS ocular manifestations. The choice of therapy needs be considered with the overall condition of patient.
The Challenges in Diagnosing Sturge-Weber Syndrome (SWS) with Corneal Disorder Rahmawati, Fika; Zuhria, Ismi
Vision Science and Eye Health Journal Vol. 5 No. 2 (2026): Vision Science and Eye Health Journal
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/vsehj.v5i2.2026.66-69

Abstract

Introduction: Sturge-Weber syndrome (SWS) or encephalofacial angiomatosis consists of a facial cutaneous vascular malformation (port-wine stain) with ipsilateral leptomeningeal vascular malformation. The characteristic facial port-wine stain involves the eyelid, anterior chamber, cornea, choroid, and retina. Other lesions sometimes seen are cataract, corneal degeneration, uveitis, intraocular haemorrhage, and heterochromia of the iris. Case Presentation: A 54-year-old woman presented with a chief complaint of right-eye glare. The patient cannot really remember when it started. Other complaints include eye pain, blurriness and discomfort. Red eyes were irritatingly denied; history of illness, hemangioma since birth, stroke, hypertension, and diabetes mellitus. The left eye has been blind for 40 years. Visual acuity from the right eye is 5/24 pinhole and 5/7.5 light perception from the left eye. The intraocular pressure (IOP) were normal in both eyes. Tear breakup time and Schirmer test showed dry eye. The segment anterior to the right eye showed a hazy cornea and lens opacity. The specular microscope showed higher coefficient variation. Conclusions: Establishing a diagnosis in SWS patient with corneal disorders is difficult, however, routine evaluation remains necessary to maintain eye health and sharp vision, especially in the last eye.