Siti Ifadatin
Department Biology, Faculty Of Mathematics And Natural Sciences, University Tanjungpura, Jl. Prof. Dr. H. Hadari Nawawi, Pontianak, West Kalimantan, Indonesia, 7811

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Anti-inflammatory Activity of Bajakah Stem (Spatholobus littoralis Hassk.) Ethanolic Extract in Carrageenan-Induced Paw Edema Mice Rousdy, Diah Wulandari; Wardoyo, Elvi Rusmiyanto Pancaning; Ifadatin, Siti
Jurnal Biodjati Vol 7 No 1 (2022): May
Publisher : UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/biodjati.v7i1.14126

Abstract

Bajakah tampala plant (Spatholobus littoralis Hassk.) has been used for traditional medicine by the Kalimantan Dayak tribe in the treatment of cancer. This study aimed to find out the potential of ethanol extract of the stem of Bajakah tampala (Spatholobus littoralis Hassk.) as an anti-inflammatory agent in carrageenan-induced mice. The method used was a Completely Randomized Design with five treatments and five replications. The treatments consisted of a water-treated mouse as a negative control, sodium diclofenac 30,8 mg kg-1 as a positive control, and an extract of bajakah dose 2.5; 250; 1250 mg kg-1 BW. The dose of bajakah extract was given orally one hour before carrageenan induction. The inflammation induction used the Winter method by injecting 0.15 ml of 2% carrageenan suspension into the soles of mice. The diameter of edema was measured for 210 minutes. The results showed that the diameter of the mice soles showed a significant increase in all groups after the carrageenan injection. The value of AUC (Area Under the Curve) of bajakah extract dose (2.5; 250; 1250 mg kg-1) from the 150th minute to the 210th minute did not show significant differences from one another. The sodium diclofenac as positive control gave the lowest total AUC value of 236 mm.minute, followed by bajakah extract at a dose of 2.5 mg kg-1 BW of 239.22 mm.minute. The calculation results of the percentage of the inflammation inhibition showed that the administration of ethanol extract of the stem of Bajakah, Spatholobus littoralis, at the lowest dose of 2.5 mg kg-1 BW provide the best inflammation inhibition with 19.21% inhibitory value, nearly approaching the positive control of diclofenac sodium with an inhibitory value of 21.53%.
Growth of Pontianak Siamese Shoot Culture (Citrus nobilis var. microcarpa) Supplemented with Tomato Extract and BAP (6-benzylaminopurine) Istiani, Duwi Rida; Mukarlina, Mukarlina; Ifadatin, Siti
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.9666

Abstract

Pontianak Siamese (Citrus nobilis var. microcarpa) is a superior agricultural commodity especially in Sambas Regency, West Borneo. One solution to assist in the supply of Pontianak Siamese seedlings is propagation with tissue culture. This research aims to determine the impact of supplementation of tomato extract and BAP on the growth of Pontianak Siamese shoot cultures. This research was conducted from February to May 2023, at Biology Laboratory, Department of Biology, Faculty of Mathematics and Natural Sciences, Tanjungpura University. The research design used a Completely Randomized factorial design with two factors. The first factor is the treatment of BAP with concentrations 0M; 10-7M; 10-6M; and 5.10-6 M, while the second factor was tomato extract with concentrations 0% 7.5%, 10%, and 12.5%. The research results show the treatment B3T0 (5.10-6 M BAP and 0% T) has the most leaves (7 strands), the longest root length (0.30 cm), and the most roots (1 root).