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Effectiveness of Kemangi (Ocimum basilicum) Leaf Methanol Extract against Candida albicans Colonies Tarsikah, Tarsikah; Widyana, Erni Dwi; Wulandari, Lisa Purbawaning
JURNAL INFO KESEHATAN Vol 20 No 2 (2022): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol20.Iss2.870

Abstract

Candida species, for women are the foremost common cause of parasitic contaminations. Candida species affect contamination in 75% of women and at slightest 6-9% of women involvement repetitive vulvovaginal candidiasis. Candida albicans (CA) accounts for 85-95% of yeast strains separated from the vagina. The treatment which has been administered for candida infections is antifungal drugs such as clotrimazole and fluconazole. When applied topically, synthetic antifungal drugs cause allergic reactions, resistance, and a burning sensation. It is necessary to conduct research on plant-based herbal medicine as an alternative treatment. Kemangi, also recognized as Ocimum Basilicum (OB), is a plant native to Indonesia which has medicinal properties. The objective of this study is to examine how effective OB methanol extract is against CA colonies. The study was performed at Brawijaya University's Microbiology Laboratory in Malang. The experimental laboratories with Posttest Only Control Group Design were employed in this study, with four repetitions of OB concentrations of 15%, 20%, 25%, 30%, and 35% against CA colonies. One-way ANOVA was utilized as the hypothesis test, with a significance level of 0.05. The results demonstrated that OB extract with a concentration of 15% was able to inhibit the growth of CA colonies. In the OB extract with a concentration of 35%, no CA colony growth was revealed. One-way ANOVA test obtained p 0.000 <0.05. Conclusion OB owns adequacy in restraining the development of CA organism with negligible murdering rate at a concentration of 35%.  Research required to be performed to identify the antifungal potential of OB extract in vivo.
The Effect of Maternal Weight Gain During Pregnancy on Uterine Contraction and Fetal Weight Zahariah, Sultanah; Rusdiarti, Rusdiarti; Widyana, Erni Dwi
Jurnal Kesehatan Prima Vol. 18 No. 1 (2024): FEBRUARY
Publisher : poltekkes kemenkes mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jkp.v18i1.1268

Abstract

The duration of labour is influenced by 3 main factors, namely power, passage, passanger. Control of these factors is thought to be able to influence the duration of labor so as to minimize the incidence of complications caused by prolonged labour.  Maternal nutritional status, one of which is the weight gain during pregnancy, allegedly affects power and passanger as factors that play an important role in labour. This study aims to determine the effect of maternal weight gain during pregnancy on uterine contractions and fetal weight at Srikandi IBI Public Hospital, Jember, East Java. This research is an observational analytic study, a cross-sectional approach with sample size of 92 mothers giving birth at Srikandi General Hospital in Jember. Collected data was analyzed by inferential analysis using path analysis. It was found that the maternal weight gain during pregnancy had a significant effect on the fetal weight (t-value 3.77 with an estimated value of 0.37), but did not affect uterine contractions either in frequency (t-value 1.62) or duration (t -value 0.69). So it can be concluded that the greater maternal weight gain during pregnancy, the greater the fetal weight. Based on the results of this study, it is hoped that health workers will provide assistance so that pregnant women pay attention to increasing body weight during pregnancy based on BMI, so that there are no labor complications due to passanger factors.