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All Journal Indonesian Journal of Mathematics and Natural Sciences Abdimas Jurnal Inovasi Pendidikan Kimia Sainteknol : Jurnal Sains dan Teknologi Chemistry in Education Indonesian Journal of Chemical Science International Journal of Community Service Learning Journal of Innovative Science Education International Journal of Active Learning Biosaintifika: Journal of Biology & Biology Education
S Mursiti
Jurusan Kimia, Fakultas Matematika Dan Ilmu Pengetahuan Alam, Universitas Negeri Semarang
Agriculture, Biological Sciences & Forestry Arts Humanities Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Law, Crime, Criminology & Criminal Justice Mathematics Social Sciences

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Uji Aktivitas Antibakteri Senyawa Triterpenoid dari Biji Karika (Carica pubescens) Farikhah, Aflin Nur; Mursiti, Sri; Prasetya, Agung Tri
Indonesian Journal of Chemical Science Vol 9 No 2 (2020)
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ijcs.v9i2.33173

Abstract

Karika merupakan tumbuhan khas dataran tingi Dieng yang bijinya dimanfaatkan oleh penduduk sekitar sebagai obat karena didalamnya terdapat kandungan metabolit sekunder diantaranya adalah senyawa triterpenoid. Tujuan dari penelitian ini adalah untuk mengetahui kandungan senyawa aktif dalam ekstrak biji karika dan efektivitasnya sebagai bakteri. Ekstraksi senyawa aktif biji karika menggunakan metode maserasi dengan pelarut n-heksan dan etanol. Ekstrak etanol dipartisi menggunakan metode ekstraksi cair-cair dengan pelarut petroleum eter. Hasil partisi dilakukan uji antibakteri terhadap Escherichia coli dan Staphylococcus aureus. Isolat diidentifikasi menggunakan spketrofotometer UV-Vis dan spektrofotometer FT-IR. Hasil identifikasi menunjukkan isolat memiliki serapan maksimum pada panjang gelombang 245 nm serta memiliki gugus fungsi O-H, C-H alifatik, C=O, gem dimetil, -C-O. Uji antibakteri yang dilakukan menggunakan metode cakram, dari hasil yang didapat menunjukkan senyawa triterpenoid hasil isolasi memiliki aktivitas antibakteri lemah dalam menghambat pertumbuhan bakteri Escherichia coli dan Staphylococcus aureus.
Isolation, Identification, and Activity Test of Flavonoid Compounds in Jamblang Leaves (Syzygium cumini L.) Skeel Jatmiko, Miracela Putri; Mursiti, Sri
Indonesian Journal of Chemical Science Vol 10 No 2 (2021)
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ijcs.v10i2.47037

Abstract

Jamblang (Syzygium cumini L.) Skeel is a plant that has the potential to be a natural antioxidant. The jamblang plant contains chemical compounds including alkaloids, flavonoids, resins, tannins, and essential oils. This study aims to identify the class of flavonoid compounds contained in jamblang leaves using a spectrophotometer UV-Vis and FTIR and to determine the antioxidant activity of jamblang leaf determined by the percentage of resistance. Determination result of antioxidant activity in ethanol extract, ethyl acetate and isolate of jamblang leave against ABTS (2,2-azino-bis(3-etilbenzotiazolin)-6-asam sulfonat) the highest percentage was shown at 40 ppm of ethyl acetate extract equal is 46,77%. The Identification results of isolate jamblang leave contained flavonoid compounds from the flavonol groups.
Exploration of Multiple Intelligences for High School Students in Chemistry Learning in Semarang City Fadloli, Muhammad; Sumarti, Sri Susilogati; Mursiti, Sri
Journal of Innovative Science Education Vol 10 No 2 (2021): August 2021
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jise.v9i3.41411

Abstract

Theory of Multiple Intelligences in education world is less so concerned. Some chemistry teachers who teach high school students in Semarang City are not aware to this theory due to lack of references. This research aims to know the level of Multiple Intelligences of high school students in Semarang City in chemistry studies according to the indicators as described by Howard Gardner. Those indicators are intelligences of verbal-linguistic, logical-mathematical, visual-spatial, physical-kinesthetic, musical-rhytmic, intrapersonal, interpersonal, and naturalist. This research is conducted in three schools which takes fifty students of XI IPA from each school using random and simple in retrieving the data. That data is collected using questionnaires which are shared to students to know the level of Mutiple Intelligences. The research data is analyzed descriptive-quantitatively, that quantitative data is only used as means of categorizing the level of students’ intelligences. The result of this study is obtained various data on each indicator. The result of quantitatively data analysis shows that naturalist intelligence is obtained at the highest percentage of 71.10%, while verbal-linguistic intelligence is obtained at the lowest percentage of 62.23%. The result of this research can be used as a reference and consideration of high school teachers in formulating a lesson plan that will be applied in chemistry learning. Based on the result of this research, it can be concluded that the level of students’ Multiple Intelligence in chemistry learning is averagely categorized as “hight level”.
Analysis of Students' Critical and Creative Thinking Skills on the Application Of A Problem-Based Learning Model Contained with Etno-Science (Etno-PBL) Patricia, Novita; Sumarni, Woro; Mursiti, Sri
International Journal of Active Learning Vol 7, No 1 (2022): April 2022
Publisher : International Journal of Active Learning

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The learning process in schools is considered not to focus on real-life problems that require critical and creative thinking skills from students. In addition, the learning carried out did not pay attention to the local culture that developed in the area. Therefore, this study aims to analyze students' critical and creative thinking skills after applying a problem-based learning model that contains ethnoscience. This study uses a mixed method with a sequential explanatory strategy. This research was conducted on students of class X MIPA SMAK Santo Thomas Aquinas Bengkayang, West Kalimantan, for the academic year 2021/2022. Test the validity of quantitative data and qualitative data using a concurrent triangulation strategy which was carried out at the same time. The results showed that the average score of critical and creative thinking skills was 77.7 and 75.9, respectively, with high levels, while the N-gain values were 0.57 (medium) and 0.72 (high). The conclusion is that ethnoscience-based problem-based chemistry learning in this study is effective in developing students' critical thinking and creative thinking skills.
Pharmacokinetics Profile of Chitosan Nanoparticles in Chronic Lead-induced Toxicity Rats Model Marianti, Aditya; Amalina, Nur Dina; Mursiti, Sri; Sitompul, Faya Nuralda; Futri, Shafira Septiana; Negara, Legendra Gantar; Sholehah, Intan Kharyna; Asmorowati, Dian Sri; Astari, Putri Dyah
Biosaintifika: Journal of Biology & Biology Education Vol. 16 No. 1 (2024): April 2024
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/biosaintifika.v15i1.1857

Abstract

Chronic lead exposure induces ROS accumulation which causes physiological disorders. Chelation therapy has been widely used to overcome lead poisoning since it exerts only a few side effects. Nano chitosan prevents lead poisoning by inhibiting ROS. This study examined the pharmacokinetics of nano chitosan in chronic lead-induced toxicity animal models and the mechanism of action pathway using the bioinformatic approach, The area under the curve was estimated to be 12110.13 ± 7709.37 μg/mL hours using the pharmacokinetic model, and the Cmax was 82.34 ± 5.64 μg/mL. The Tmax and t½ calculations were 22.68 ± 11.67 and 80.47 ± 60.58 hours respectively. Chitosan nanoparticles regulated VEGFA, FGF2, and LGALS3 which plausibly played a substantial role in chronic lead exposure. However, chitosan is not suitable for oral administration due to its low gastrointestinal solubility. These characteristics make chitosan nanoparticles have the prospect of being developed as a supplement so that they can contribute to overcoming the negative impacts of chronic lead poisoning.
Preparation of the Gubung Serut Area to be an Educational Nature Tourism Destination Parmin; Widiatningrum, Talitha; Mursiti, Sri; Adhi, Aryono
International Journal of Community Service Learning Vol. 6 No. 3 (2022): August 2022
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/ijcsl.v6i3.51328

Abstract

This service aims to provide assistance to the community in the Gubung Serut area to prepare educational natural tourist destinations. Mentoring involves partners from PT. Astra International Tbk., Honda Central Java region. Community empowerment applies a participatory method through the stages of community empowerment through the stages of preparation, implementation, and evaluation. Preparation is carried out through the stages of establishing partnerships to build a shared commitment to developing empowerment programs in target locations. The empowerment program is prepared jointly between the service team, village officials, and target community leaders. Data during the empowerment process and activity achievements were collected through interviews and observations. Interviews reveal the opinion of tourism managers about knowledge gained during empowerment activities and benefits obtained in setting up educational tourism areas. The number of visitors to the tourist area every week has reached more than 100 people. The most attractive tourist destinations for visitors are natural panoramas and educational attractions. Preparing the Gubung Serut tourist area to become an educative natural tourism destination has been carried out through preparing management resources, building destinations, and preparing educational tourist attractions. The development of the Gubung Serut tourist area needs to be done with a broader partnership. The culinary and artistic potential still needs to involve partners more broadly to increase the diversity of tourist attractions that attract visitors.
Co-Authors - Jumaeri A.A. Ketut Agung Cahyawan W Achmad Binadja Aditya Marianti Agung Tri Prasetya Amalina, Nur Dina Antonius Tri Widodo Arini Ainul Hanifah Aryono Adhi, Aryono Asih, Amanah Galih Asih, Amanah Galih Asokawati, Bunga Mahardhika Astari, Putri Dyah Cahyaningrum, Intan Dian Sri Asmorowati Dianto - E Kusumo, E Edy Cahyono Endang Susilaningsih Ersanghono Kusumo, Ersanghono Fadloli, Muhammad Farikhah, Aflin Nur Feliana, Kiki Feliana, Kiki Futri, Shafira Septiana Harjono Harjono Ida Nur Laelly Imam Supardi, Kasmadi Jati, Ninda Kirana Jatmiko, Miracela Putri Jumina Jumina Kusoro Siadi M H Setiawan, M H M. Alauhdin, M. Mabruroh, Eva Qomariyah Mabruroh, Eva Qomariyah Marfina, Apriza Maulana, Alfian Maulana, Alfian Muhammad Afif Mustofa . Mustofa Mustofa Nada, Ella Izzatin Nanik Wijayati Negara, Legendra Gantar Ningtyas, Yanuar Ayu Novia Tina Anjani, Novia Tina Nufus, Khayatun Nufus, Khayatun Nugraha, Aditya Cahya Nugraha, Aditya Cahya Nuni Widiarti Nur Hidayah Nurcahyo, Bowo Nurcahyo, Bowo Nurul Inayah Oktaviana, Sella Parmin Patricia, Novita Prayitno, Mohammad Agus Putri, R Ratna Dewi Kusumaningtyas Rizalina, Hartias Rizalina, Hartias Rizkita, Aden Dhana S Matsjeh Sabirin Matsjeh Saptorini - Sari, Ria Ajeng Putri Nur Indah Sari, Ria Ajeng Putri Nur Indah Sholehah, Intan Kharyna Siti Handayani siti novita sari, siti novita Sitompul, Faya Nuralda Sri Haryani Sri Mantini Rahayu S Sri Susilogati Sumarti Sudarmin - Sudarmin, . Sudarmin, . Sumarni, W Supartono - Supartono, Supartono Syifa Fauziyah, Syifa Talitha Widiatningrum Titi Wahyukaeni Triastuti Sulistyaningsih Tunnisa, Tasqia Tunnisa, Tasqia Veronita, Fanna Veronita, Fanna Woro Sumarni Yanti, Arisma Yanti, Arisma Yuka Ediristianto