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PENGARUH PEMBERIAN EXTRA VIRGIN OLIVE OIL TERHADAP BERAT JANIN PADA RATUS NOVERGICUS MODEL PREEKLAMSIA Dwi Norma Retnaningrum; Wenny Rahmawati
Conference on Innovation and Application of Science and Technology (CIASTECH) CIASTECH 2020 "Peranan Strategis Teknologi Dalam Kehidupan di Era New Normal"
Publisher : Universitas Widyagama Malang

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ABSTRAKPreeklamsia merupakan suatu gangguan komplikasi selama kehamilan dan nifas. Preeklamsia menempati urutan ke 2 dalam menyumbang angka kematian ibu (AKI). Preeklamsia menempati urutan 1 sebagai penyebab kematian ibu di Jawa Timur pada tahun 2016. Efek samping yang ditimbulkan preeklamsia tidak hanya pada ibu saja melainkan juga terhadap janin. Extra Virgin Olive Oil (EVOO) diperoleh dari buah zaitun yang pemrosesannya dengan cara mekanik sehingga tidak merubah komposisi pada zaitun. Penelitian tentang EVOO sudah banyak diteliti namun dalam spektrum luas yaitu dengan mengexplorasi kandungannya sebagai antiinflamasi dan juga antioksidan. Hasil pemeriksaan yang telah dilakukan oleh peneliti di dapat hasil 48,56 yang berarti sangat kuat. Penelitian ini bertujuan untuk membuktikan peran EVOO terhadap berat janin pada ratus novergicus model preeklamsia. Rancangan penelitian ini adalah eksperimen (quasi experimental) dengan pendekatan post test only control group design. penelitian ini terdiri dari 5 kelompok yaitu kelompok negatif, kelompok positif ( tikus model preeklamsia), kelompok perlakuan 1 (pemerian EVOO 0,5ml/hari), kelompok perlakuan 2 (pemberian EVOO 1ml/hari), dan kelompok perlakuan 3 (pemberian EVOO 2ml/hari). Setelah dikorbankan, janin di timbang untuk mengetahui beratnya. Hasil penelitian menunjukkan pemberian EVOO efektif meningkatkan berat janin pada tikus model preeklamsia dengan P value 0.000 (p<0.05).

Pengaruh EVOO (Extra Virgin Olive Oil) Terhadap Tekanan Darah dan Kadar Protein Urin Pada Tikus Model Preeklamsia Wenny Rahmawati; Dwi Norma Retnaningrum; Alfima Rahasti
DINAMIKA KESEHATAN: JURNAL KEBIDANAN DAN KEPERAWATAN Vol 11, No 2 (2020): Dinamika Kesehatan Jurnal Kebidanan dan Keperawatan
Publisher : Universitas Sari Mulia

Latar Belakang:Â Preeklamsia merupakanÂ komplikasi kehamilan yang menyebabkan lebih dari 25% kematian ibu di Indonesia.Â Mekanisme yang terlibat pada pathogenesis preeklamsia yaitu disfungsi endotel dan peningkatan stress oksidatif sehingga menyebabkan kerusakan vaskuler sistemik yang bermanifestasi menjadi sindrom preeklamsia seperti hipertensi, proteinuria dan odema. Sampai saat ini cara mengobati preeklamsia dengan mengakhiri kehamilan. EVOO (Extra Virgin Olive Oil)Â Â merupakan salah satu sumber antioksidan alami dari tanaman.Â EVOOÂ memiliki profil asamlemakÂ (FA)Â denganÂ Â rasioÂ monounsaturated fatty acid (MUFA) atau asam lemak tak jenuh tunggalÂ yangÂ tinggiÂ danÂ jugakandungan antioksidanÂ yangÂ kaya.Â Tujuan:Â Tujuan penelitian ini adalah untuk membuktikan bahwa EVOO dapat menurunkan tekanan darah dan protein urin pada tikus model preeklamsia.Â Metode:Â Penelitian dilakukan secaraÂ true experimentalÂ -Â post test only control group design.Â Menggunakan 20 ekorÂ Rattus NovergicusÂ yang dibagi menjadi 5 kelompok yaitu kelompok perlakuanÂ Kelompok kontrol negatif (tikus bunting sehat), kontrol positif (tikus bunting dengan preeklamsia), kelompok perlakuan satu, perlakuan dua dan perlakuan tiga dimana kelompok perlakuan adalah tikus bunting preeklamsia yang diberi EVOO dengan berbagai dosis (0,5 cc, 1 cc dan 2 cc).Â Hasil:Â Hasil penelitian analisis data statistik menunjukan adanya perbedaan bermakna antara masing-masing dosisÂ (p=0,000Î±). Kandungan polifenol dan flavonoid yang tinggi pada EVOO akan meningkatkan antioksidan yang berperan sebagai penyeimbang radikal bebas pada kondisi preeklamsia.Â Kesimpulan:Â EVOO (Extra Virgin Olive Oil) dapat menurunkan tekanan darah dan kadar protein urin pada preeklamsia.Â Kata Kunci:Â EVOO, Protein Urin, Tekanan DarahÂ Background: Preeclampsia is a pregnancy complication that causes more than 25% of maternal deaths in Indonesia. The mechanisms involved in the pathogenesis of preeclampsia are endothelial dysfunction and increased oxidative stress, which causes systemic vascular damage which manifests as a preeclampsia syndrome such as hypertension, proteinuria and odema. Until now, the way to treat preeclampsia is by ending pregnancy. EVOO (Extra Virgin Olive Oil) is a source of natural antioxidants from plants. EVOO has a fatty acid profile (FA) with a high ratio of monounsaturated fatty acids (MUFA) or monounsaturated fatty acids and also a rich antioxidant content.Objective: The purpose of this study was to prove that EVOO can reduce blood pressure and protein urine in rat with preeclampsia.Methods: The research was conducted in true experimental - post test only control group design. Using 20 Rattus Novergicus heads divided into 5 groups, namely the treatment group, the negative control group (healthy pregnant rat), the positive control (pregnant rats with preeclampsia), treatment group one, treatment two and treatment three where the treatment group was preeclamptic pregnant rat given EVOO with various doses (0.5 cc, 1 cc and 2 cc).Result: The results of the statistical data analysis study showed that there was a significant difference between each dose (p = 0.000 Î±). The high content of polyphenols and flavonoids in EVOO will increase antioxidants which act as a counterweight to free radicals in preeclampsia.Conclution: EVOO (Extra Virgin Olive Oil) can lower blood pressure and protein urine levels in preeclampsia.Â Keywords: EVOO, Protein Urine, Blood Pressure

The Role of Mothers Knowledge Regarding Nutritional Needs of Toddlers Nutritional Status Wenny Rahmawati; Dwi Norma Retnaningrum
Jurnal MID-Z (MIDWIFERI ZIGOT) Vol 5 No 2 (2022): NOVEMBER
Publisher : Universitas Islam Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56013/jurnalmidz.v5i2.1638

The issue of nutrition is set as an essential point in the Sustainable Development Goals (SDGs). One of the SDGs targets related to nutrition is that by 2030 all forms of malnutrition in children under five must end. The incidence of malnutrition in children under five is strongly influenced by the knowledge of parents. Knowledge of nutrition is an essential provision for mothers to provide balanced nutrition for their toddlers. The purpose of the study was to prove the role of mother's knowledge regarding nutritional needs on nutritional status of children under five in Sukomulyo Village. The research design is correlational analytic approach cross sectional Data was collected on 74 mothers who have toddlers using stratified random sampling technique. The results of the study showed that the mother's knowledge about nutritional needs was mostly (50%) sufficient. Most of the nutritional status of children under five (66.2%) is good.test Spearman rank obtained the rs value of 0.405 and the p value (sig.) = 0.000 < 0.05. Researchers suggest the need for mothers of toddlers to further increase their knowledge about the nutritional needs of toddlers, so that the nutritional status of toddlers can be improved even more and can prevent malnutrition.

The Role of Mothers Knowledge Regarding Nutritional Needs of Toddlers Nutritional Status Wenny Rahmawati; Dwi Norma Retnaningrum
Jurnal MID-Z (MIDWIFERI ZIGOT) Vol 5 No 2 (2022): NOVEMBER
Publisher : Universitas Islam Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56013/jurnalmidz.v5i2.1638

The issue of nutrition is set as an essential point in the Sustainable Development Goals (SDGs). One of the SDGs targets related to nutrition is that by 2030 all forms of malnutrition in children under five must end. The incidence of malnutrition in children under five is strongly influenced by the knowledge of parents. Knowledge of nutrition is an essential provision for mothers to provide balanced nutrition for their toddlers. The purpose of the study was to prove the role of mother's knowledge regarding nutritional needs on nutritional status of children under five in Sukomulyo Village. The research design is correlational analytic approach cross sectional Data was collected on 74 mothers who have toddlers using stratified random sampling technique. The results of the study showed that the mother's knowledge about nutritional needs was mostly (50%) sufficient. Most of the nutritional status of children under five (66.2%) is good.test Spearman rank obtained the rs value of 0.405 and the p value (sig.) = 0.000 < 0.05. Researchers suggest the need for mothers of toddlers to further increase their knowledge about the nutritional needs of toddlers, so that the nutritional status of toddlers can be improved even more and can prevent malnutrition.

The Effect of Extra Virgin Olive Oil to Decrease HSP-90, TNF-Α and ET-1, in Pre-Eclampsia Rat Model Wenny Rahmawati
Journal of Global Pharma Technology Volume 12 Issue 01
Publisher : Journal of Global Pharma Technology

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ABSTRACTBackground: Preeclampsia characterised by new-onset hypertension with systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg, measured on two occasions at least four hours apart, and proteinuria of > 0.3 g per 24 hours or ≥ 1+ proteinuria, detected by urine dipstick after 20 weeks of pregnancy, or in the absence of proteinuria. Objectived: This study aimed to determine effect of EVOO as a strong exogenous antioxidant to decrease TNF-α, HSP-90 and ET-1 level in preeclampsia rat model. Method: This research consisted of five groups; negative control, positive control (preeclampsia rat model), doses 1, 2, and 3 that were preeclampsia rats given EVOO in 3 different doses (0.5 mL/day, 1 mL/day and 2 mL/day respectively). After sacrificed, placentas were collected to determine HSP-90, TNF-α and ET-1 level. Result: Result of this study showed that there was a reduction of HSP90 (p=0,00), TNF-α (p=0.011), ET-1 (p=0.02). Conclusion: Administration EVOO decreased HSP-90, TNF-α and ET-1 Level in preeclampsia rat modelKeywords: Preeclampsia, EVOO, HSP-90, TNF-α, ET-1, Antioxidant, Oxidative stress.

Antibacterial Activity Test of Mahkota Dewa Fruit (Phaleria macrocarpa) Extract against Escherichia Coli Bacteria Dwi Norma Retnaningrum; Wenny Rahmawati
EMBRIO: Jurnal Kebidanan Vol 15 No 1 (2023): EMBRIO: Jurnal Kebidanan (MAY)
Publisher : Program Studi S1 Kebidanan - Fakultas Ilmu Kesehatan Universitas PGRI Adi Buana Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/embrio.v15i1.6533

Exposure to Escherichia coli during pregnancy may cause serious problems such as anemia, premature birth and an increased risk of inflammation of the lining of the brain in the fetus. Mahkota Dewa (Phaleria macrocarpa) is a medicinal plant that is widely known and used to treat allergies and chronic diseases. One of the compounds contained in Mahkota Dewa is flavonoids. There is certain mechanism of action of flavonoids in inhibiting bacteria namely by damaging the cytoplasmic cell wall in bacteria. This study aims to analyze the antibacterial properties of various flavonoid concentrations of Mahkota Dewa fruit (Phaleria macrocarpa) extract against Escherichia coli bacteria through a laboratory experimental study design by testing the antimicrobial potency of the well method, namely 10percent, 20percent, 40percent, 60percent, 80percent and 100percent. Statistical analysis using One-Way Anova Test showed a significant difference between changes in the concentration of flavonoids in Mahkota Dewa fruit extract and the inhibition zones towards the growth of Escherichia coli bacteria (p less than 0.05). Pearson correlation test showed a very strong relationship with a positive direction (r equals 0.874) which indicated that the higher the concentration of flavonoids in Mahkota dewa fruit extract, the stronger the antimicrobial effect. Based on the study findings, it can be concluded that the flavonoid extract in Mahkota Dewa fruit extract had an antimicrobial potential against Escherichia Coli in vitro.

Kecerdasan Emosional dan Efikasi Diri Mempengaruhi Stres Kerja Pada Tenaga Kesehatan Wenny Rahmawati; Dwi Norma Retnaningrum
Jurnal Vokasi Kesehatan Vol 8, No 2 (2022): Juli 2022
Publisher : Poltekkes Kemenkes Pontianak

Wabah Covid-19 menyebabkan berbagai gangguan psikologis yang telah dilaporkan dan dipublikasikan salah satunya yaitu stres kerja tenaga kesehatan. Kecerdasan emosional dan efikasi diri adalah salah satu faktor yang menentukan kualitas kerja tenaga kesehatan. Tenaga kesehatan akan melaksanakan tugas dan tanggung jawabnya dengan baik apabila mempunyai kecerdasan emosional dan efikasi diri yang tinggi. Penelitian bertujuan untuk mengetahui hubungan kecerdasan emosional dan efikasi diri terhadap stres kerja pada tenaga kesehatan RSIA MH Kota Malang dan dilakukan selama bulan Juni-Juli 2021. Desain penelitian ini adalah analitik korelasional dengan jenis penelitian menggunakan pendekatanÂ cross sectionaldengan jumlah 66 responden. Instrument penelitian menggunakan 3 kuesioner. Analisis dataÂ menggunakan ujiÂ multiple correlation.Hasilnya didapatkan tenaga kesehatan RSIA Melati Husada dengan kecerdasan emosional rendah sebesar 40,9%, efikasi diri rendah yaitu 53% dan stres kerja sedang (53%). Analisis menggunakan uji korelasiÂ hubungan kecerdasan emosional dan stres kerjaÂ didapatkan nilai r hitungÂ Â = - 0,316 dan hubungan antara efikasi diri dengan stress kerja r hitung = -0,347.Tingginya kecerdasan emosional maka akan di ikuti oleh rendahnya stres kerja. Tingginya efikasi diri maka akan di ikuti oleh penurunan stres kerja.

Hubungan Pola Asuh Orang Tua terhadap Kejadian Diabetes pada Anak Usia Sekolah Wenny Rahmawati; Ika Arum Dewi Satiti
Oksitosin : Jurnal Ilmiah Kebidanan Vol. 11 No. 2 (2024): OKSITOSIN : Jurnal Ilmiah Kebidanan
Publisher : Prodi D III Kebidanan Fakultas Ilmu Kesehatan Universitas Ibrahimy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35316/oksitosin.v11i2.4560

Elevated blood sugar levels are a sign of a metabolic disease called Diabetes Mellitus (DM). Several factors including the environment are contributors to the incidence of DM. The role of parents is mainly related to the child's lifestyle, including diet and food intake for the child. The lifestyle fostered in the family will affect the health of children. The purpose of this study was to analysis the parenting style of parents towards early diagnosis of diabetes based on blood glucose levels in children. A cross-sectional design and descriptive correlational design were used for this study. This study involved all students at SDN 2 Kepuharjo in August 2023 involving 92 children with total sampling technique. This study used the Parental Authority Questionaire instrument, which consists of twenty question items that assess how parenting is done. Details of the characteristics of the respondents were mostly 11 years old with 47 children (51.1%) and were in grades 5 and 6. The most respondents were female with 49 children (53.3%). Working mother status was at 84 (91.3%). 53 children with less parenting (57.6%). The results of the examination of blood sugar levels obtained were 17 children (18.5%) in the high category. Conclusion There is a correlation between parenting patterns and the number of cases of diabetes in school-age children in elementary schools with a p value of 0.006.

EMPOWERING TEENAGERS AWARE OF NUTRITIONAL STATUS AS AN EFFORT TO PREVENT STUNTING Sulistyowati, Agus; Kusbandiyah, Jiarti; Rahmawati, Wenny; Annisa, Faida
Community Service Journal of Indonesia Vol 5 No 2 (2023): Community Service Journal of Indonesia
Publisher : Institute for Research and Community Service, Health Polytechnic of Kerta Cendekia, Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36720/csji.v5i2.619

Indonesia is a developing country that has quite high nutritional problems. Efforts to improve nutritional status must begin as early as possible, precisely starting from the fetal life period. This period is the early period of life when you are still in the womb until the first 2 years of life. The focus of handling nutritional problems is to prevent malnutrition which is a major health problem in toddlers because it can hinder the growth and development process during the First 1000 Days of Life. There is a need for knowledge regarding stunting in teenagers because teenage girls will face the pregnancy period which is important in preventing stunting. This counseling was carried out in Srigonco Village, Malang Regency. The target of this community service is all junior high school students from grade 7 to grade 9. Prior to carrying out extension activities, there is a process of preparing activities for approximately four weeks prior to implementation activities, starting from determining the type of extension to applying for permits to related parties. As a form of evaluation, the activity was attended by 35 students from grade 7 to grade 9, the participants took part in the activity with very enthusiasm, and the counseling activities ran smoothly.

THE THE ROLE OF NUTRITIONAL STATUS ON HEMOGLOBIN LEVELS IN ADOLESCENTS Kusbandiyah, Jiarti; Rahmawati, Wenny; Sulistyowati, Agus
Nurse and Health: Jurnal Keperawatan Vol 13 No 1 (2024): Nurse and Health: Jurnal Keperawatan
Publisher : Institute for Research and Community Service of Health Polytechnic of Kerta Cendekia, Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36720/nhjk.v13i1.637

Background: Adolescents were one of the strong foundations for the future of the nation because of their role in development and progress of the country. Healthy physical and psychological conditions will form a strong and resilient adolescent character which is affected by adequate nutritional intake. So that if nutrients are not sufficient, it can cause disturbances in metabolic processes. Inadequate intake of nutrients such as protein and iron will aggravate the occurrence of anemia and lead to malnutrition. Indirectly, nutritional status will also affect the occurrence of anemia. Objectives: This study was to examine the relationship between nutritional status and adolescent hemoglobin levels. Methods: This study was an analytic study with Cross Sectional approach. Respondents were 46 students of SMP PGRI 01 Bantur in Malang regency conducted in August 2023. Independent variable was nutritional status using weight, height and Body mass index (BMI) and dependent variable was anemia using hemoglobin level. BMI was calculated using formula weight divided by height square. The analysis used both univariate and bivariate analysis. Bivariate analyzed using Spearman rank correlation test. Results: Results showed 76,1% adolescents classified normal nutritional, 19,6% overweight and 2,2% underweight and obese. The hemoglobin level, 86,9% normal and 13,1% anemia. Based on the results of statistical tests using rank spearman test, the p value = 0.044 less than 0,05. It means there was a significant correlation between nutritional status and anemia. Conclusion: There is a relationship between nutritional status with Hb levels in adolescents. Enrichment of nutritional intake will give big impact on nutritional and anemia status among adolescents.

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