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The Effect of Growth and Development Stimulation on the Development of Infants with Cancer Aged 1–3 Years (Toddlers) Kustiani, Fifit Kustiani; Rahmawati, Wenny Rahmawati; Maghfiroh, Dinda Oktia Maghfiroh
Media Husada Journal of Midwifery Science Vol. 3 No. 2 (2025): Juli
Publisher : LPPM Widyagama Husada Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33475/mhjms.v3i2.24

Abstract

Abstract The growth and development of children aged 1–3 years (toddlers) suffering from cancer often face obstacles due to the impact of the disease and the therapies undergone, such as chemotherapy and radiation. Developmental delays can affect children's motor, cognitive, language, and social aspects. Providing growth and development stimulation is one intervention that can help optimize child development under these conditions. This study aims to analyze the effect of growth and development stimulation on the development of toddlers with cancer. This study used a pre-experimental method with a One-Group Pre-Post Test Design approach. The sampling technique used was non-probability sampling with purposive sampling. Data collection was conducted through observations of children's development before and after the intervention of growth and development stimulation. Data analysis was performed using the Wilcoxon Sign Rank Test to examine differences in development before and after stimulation. The statistical test results showed a p-value of 0.000, indicating a significant effect of growth and development stimulation on the development of children aged 1–3 years with cancer. This study concludes that growth and development stimulation plays a crucial role in improving the development of children experiencing delays due to cancer. Therefore, it is recommended that healthcare professionals and parents provide appropriate and continuous stimulation to support optimal child growth and development. Abstrak Pertumbuhan dan perkembangan anak usia 1–3 tahun (batita) yang menderita kanker sering mengalami hambatan akibat dampak penyakit dan terapi yang dijalani, seperti kemoterapi dan radiasi. Keterlambatan perkembangan dapat berpengaruh pada aspek motorik, kognitif, bahasa, dan sosial anak. Pemberian stimulasi tumbuh kembang menjadi salah satu intervensi yang dapat membantu mengoptimalkan perkembangan anak dalam kondisi tersebut. Penelitian ini bertujuan untuk menganalisis pengaruh pemberian stimulasi tumbuh kembang terhadap perkembangan batita yang menderita kanker. Penelitian ini menggunakan metode pra-eksperimental dengan pendekatan One Group Pre-Post Test Design. Teknik sampling yang digunakan adalah non-probability sampling dengan jenis purposive sampling. Pengumpulan data dilakukan dengan observasi perkembangan anak sebelum dan sesudah intervensi stimulasi tumbuh kembang. Sampel yang digunakan pada penelitian ini adalah 30 batita yang menderita kanker di Ruang Tondano RSUD dr. Saiful Anwar Malang. Analisis data menggunakan Wilcoxon Sign Rank Test untuk menguji perbedaan perkembangan sebelum dan sesudah pemberian stimulasi. Hasil uji statistik menunjukkan nilai p = 0,000 yang berarti terdapat pengaruh yang signifikan dari pemberian stimulasi tumbuh kembang terhadap perkembangan anak usia 1–3 tahun yang menderita kanker. Dari penelitian ini dapat disimpulkan penelitian bahwa stimulasi tumbuh kembang memiliki peran penting dalam membantu meningkatkan perkembangan anak yang mengalami keterlambatan akibat kanker, terutama yang menjalani kemoterapi. Oleh karena itu, disarankan agar tenaga kesehatan dan orang tua memberikan stimulasi yang sesuai dan berkelanjutan guna mendukung pertumbuhan serta perkembangan anak dalam kondisi yang optimal.
The Relationship Between Long-Term Usage Of Hormonal Contraception And Sexual Dysfunction And Quality Of Women's Sexual Life Windyaningrum, Sabatina; K.W.M. Justus, Dwi Murwani K.W.M. Justus; Rahmawati, Wenny Rahmawati
Media Husada Journal of Midwifery Science Vol. 3 No. 2 (2025): Juli
Publisher : LPPM Widyagama Husada Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33475/mhjms.v3i2.27

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Long-term use of hormonal contraception is suspected to have side effects, decreasing women's libido,thus affecting their sexual function and quality. Experts call this sexual dysfunction. This study aims todetermine the relationship between long-term use of hormonal contraception and sexual dysfunction andthe quality of women's sexual lives at TPMB Mudjiasri. The study was conducted from August toNovember 2024. The research method used an analytical observational approach with a cross-sectionalapproach. A sample of 30 people was drawn using total sampling that met the inclusion and exclusioncriteria. Statistical tests used univariate and bivariate Spearman Rank analysis. The results showed that12 respondents (40%) had used hormonal contraception for 3-6 years, 10 people (33.3%) had used it formore than 6 years up to 9 years, and 8 people (26.7%) had used hormonal contraception for more than9 years. Furthermore, of the 30 respondents, 93.3% (28 people) experienced sexual dysfunction and 6.7%(2 people) did not experience sexual dysfunction. In addition, 83.3% (25 people) had an unsatisfactoryquality of sexual life and 16.7% (5 people) had a satisfactory quality of sexual life. The correlation testusing Spearman Rank obtained a p-value of 0.112 in the relationship between the duration of hormonalcontraceptive use and sexual dysfunction, which means there is no relationship between the twovariables. In addition, no significant relationship was found between the duration of hormonalcontraceptive use and the quality of women's sexual life with a p-value of 0.416. The duration of hormonalcontraceptive use does not directly affect the state of sexual dysfunction and the quality of a woman'ssexual life. In addition, the causes of sexual dysfunction experienced by acceptors can be influenced byseveral factors, including age, occupation, knowledge, social environment, and communication, whichstill require further in-depth research. The conclusion of this study is that there is no relationship betweenthe duration of hormonal contraceptive use and sexual dysfunction and the quality of women's sexual life.
The Pathophysiology of Gestational Diabetes Mellitus: Literature Review Rahmawati, Wenny Rahmawati; Windyaningrum, Sabatina Windyaningrum
Media Husada Journal of Midwifery Science Vol. 3 No. 2 (2025): Juli
Publisher : LPPM Widyagama Husada Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33475/mhjms.v3i2.28

Abstract

Uji Aktivitas Antibakteri Ekstra Virgin Olive Oil (EVOO) Terhadap Streptococcus Agalactiae Rahmawati, Wenny; Retnaningrum, Dwi Norma
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 11, No 3 (2023): EDITION NOVEMBER 2023
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33366/jc.v11i3.4623

Abstract

Streptococcus agalactiae is a pathogen known to frequently cause infections in both mothers and children. It can lead to complications such as premature birth, premature rupture of membranes, postpartum infections, pneumonia, meningitis, and sepsis. Current treatment for Streptococcus agalactiae often involves antibiotics, which can contribute to antibiotic resistance. Given the increasing concern about antibiotic resistance, the development of herbal antibacterials is gaining momentum, with extra virgin olive oil (EVOO) being one such area of interest. EVOO contains oleuropein, flavonoids, and essential oils, all of which possess antibacterial properties. The objective of this research is to demonstrate the antibacterial activity of extra virgin olive oil (EVOO). The study employed a true experimental design with a post-test-only control group, using the disc diffusion method to measure bacterial inhibition zones. The results revealed the largest inhibition zone, measuring 15.9 mm, with a 3 ml dose of EVOO. The correlation test indicated a significant value of 0.000, with a coefficient of -726, suggesting that an increase in EVOO dose results in a reduction in the Streptococcus agalactiae bacterial population. Based on these findings, it can be concluded that extra virgin olive oil (EVOO) exhibits potent antibacterial activity against Streptococcus agalactiae. 
Uji Flavonoid Ekstrak Buah Mahkota Dewa (Phaleria Macrocarpa) dengan Metode (Microwave Assistted Extration) terhadap Stephylococcus Epidermidis Retnaningrum, Dwi Norma; Rahmawati, Wenny
MAHESA : Malahayati Health Student Journal Vol 5, No 1 (2025): Volume 5 Nomor 1 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i1.16284

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ABSTRACT Bacterial infection is one of the causes of mastitis problems in the postpartum period. Bacteria that cause mastitis include Stapilococus epidermidis. Mahkota dewa is a plant that is usually used for traditional medicine because it contains many active compounds that are used as anti-microbials including flavonoids. Flavonoids act as antibacterials by stopping the dissolution of nucleic acids, membrane function and energy metabolism. Microwave Assisted Extration (MAE) is an increasingly rapid and efficacious extraction method. This study aims to see how crown fruit extract (Phaleria macrocarpa) affects Staphylococcus Epidermidis bacteria in vitro using the laboratory well diffusion technique. Concentrations of 10%, 20%, 30%, 40%, 60%, 80%, 100% and a bacterial control group with no mahkota dewa fruit extract (0% concentration) were used. This study used the nonparametric Kruskal Wallis test and the Mann Whitney post-hoc test, which resulted in a significant value of 0.000. The Mann hitney t-test results obtained insignificant values at concentrations of 10%, 20%. In contrast, at concentrations of 40%, 60%, 80% and 100% there were significant differences in the colonies of Staphilococus epidermidis bacteria. The higher the concentration of flavonoid extract given, the higher the level of inhibition against Staphilococus epidermidis bacteria.   Keywords: Mahoka Dewa Fruit, Staphilococus Epidermidis   ABSTRAK Infeksi bakteri merupakan salah satu penyebab terjadi masalah mastitis pada masa nifas. Bakteri yang menyebabkan mastitis diantaranya adalah Stapilococus epidermidis. Mahkota dewa merupakan tumbuhan yang biasanya dipakai untuk obat tradisional karena kandungan di dalamnya banyak senyawa aktif yang di gunakan sebagai anti mikroba diantaranya flavonoid. Flavonoid bertindak sebagai antibakteri dengan menghentikan peleburan asam nukleat, fungsi membran dan metabolisme energi. Microwave Assisted Extration (MAE) adalah cara ekstraksi yang makin cepat dan berkasiat. Studi ini bertujuan untuk melihat bagaimana ekstrak buah mahkota dewa (Phaleria macrocarpa) mempengaruhi bakteri Staphylococcus Epidermidis secara in vitro memakai teknik difusi sumuran di laboratorium. Digunakan konsentrasi 10%, 20%, 30%, 40%, 60%, 80%, 100% serta golongan kontrol bakteri tidak ada ekstrak buah mahkota dewa (konsentrasi 0%). Studi ini menggunakan uji kruskal wallis nonparametrik dan uji Mann Whitney post-hok, yang menghasilkan nilai signifikan 0.000. Hasil uji Mann hitney t-tes dapatkan nilai tidak signifikan pada konsentrasi 10%, 20%. Sebaliknya di konsentrasi 40%, 60%, 80% dan 100% terdapat perbedaan signifikan terhadap koloni bakteri Staphilococus epidermidis. Semakin tinggi konsentrasi ekstrak flavonoid yang di berikan semakin tinggi tingkat penghambatan terhadap bakteri Staphilococus epidermidis.  Kata Kunci: Buah Mahkota Dewa, Staphilococus Epidermidis
Pemberdayaan Kader Pemberian Makanan Pendamping ASI (MPASI) Premium dalam Upaya Pencegahan Stunting: Empowerment of Cadres for Providing Premium Complementary Feeding (MPASI) in an effort to Prevent Stunting Rahmawati, Wenny; Retnaningrum, Dwi Norma
Poltekita: Jurnal Pengabdian Masyarakat Vol. 4 No. 3 (2023): Juli-September
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v4i3.1813

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Stunting is a health problem that is the main focus of all groups. One of the efforts to prevent stunting is by providing balanced nutritional complementary food for toddlers. MPASI Premium is MPASIwhich comes from family food, not ready-to-eat food or certain factory products. Giving premium MPASI is more recommended because it will make it easier for babies to get used to family food which will be consumed at a higher age.Stunting incidents in Sukomulyo Village reached 14.5% or 128 toddlers of the total number of stunting incidents in Pujon District. The results of a survey conducted in June 2022 with village midwives and several cadres stated that 83% of mothers chose to provide instant complementary food (MPASI), because it was more practical and babies ate more voraciously with instant food. Mother's knowledge of essential nutrients in solids is also lacking. The purpose of this service activity is to increase cadre knowledge regarding Premium MPASI. The solutions offered include empowerment, training and mentoring of Posyandu toddler cadres in Sukomulyo village regarding the creation of a Premium MPASI menu variant. The method used is counseling and training in making Premium MPASI products. The results of the activity formed 10 MPASI Premium Companion cadres and there was an increase in the knowledge of the cadres regarding stunting prevention and Premium MPASI.
PENYULUHAN KADER POSYANDU TENTANG PREEKLAMSIA DAN UPAYA PENCEGAHAN KOMPLIKASI KEHAMILAN Dwi Norma Retnaningrum; Wenny Rahmawati
Media Husada Journal Of Community Service Vol. 4 No. 2 (2025): Media Husada Journal of Community Service
Publisher : STIKES Widyagama Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33475/mhjcs.v4i2.57

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Abstrak Preeklamsia merupakan salah satu komplikasi kehamilan yang menjadi penyebab utama kematian ibu dan bayi di Indonesia. Kader posyandu sebagai ujung tombak pelayanan kesehatan masyarakat memiliki peran penting dalam deteksi dini dan pencegahan preeklamsia. Namun, pengetahuan kader tentang preeklamsia masih terbatas. Tujuannya meningkatkan pengetahuan dan keterampilan kader posyandu dalam mengenali tanda-tanda preeklamsia serta upaya pencegahan yang dapat dilakukan di tingkat komunitas. Kegiatan pengabdian masyarakat dilaksanakan melalui penyuluhan dan pelatihan kepada 10 kader posyandu di wilayah kerja Puskesmas Pembantu Desa Sukomulyo. Metode yang digunakan meliputi ceramah interaktif, diskusi, demonstrasi pengukuran tekanan darah, dan simulasi kasus. Evaluasi dilakukan melalui pre-test dan posttest. Hasilnya terjadi peningkatan signifikan pengetahuan kader tentang preeklamsia dari rata-rata 45,2% menjadi 82,7%. Keterampilan kader dalam mengukur tekanan darah dan mengenali tanda bahaya kehamilan juga meningkat secara bermakna. Penyuluhan efektif meningkatkan pengetahuan dan keterampilan kader posyandu tentang preeklamsia. Diperlukan program berkelanjutan untuk mempertahankan dan meningkatkan kompetensi kader.
Extra Virgin Olive Oil Supplementation Reduces Anthropometric Risk Factors for Type 2 Diabetes in Adolescent Girls Rahmawati, Wenny; Retnaningrum, Dwi Norma
EMBRIO: Jurnal Kebidanan Vol 17 No 2 (2025): EMBRIO: Jurnal Kebidanan
Publisher : Program Studi S1 Kebidanan - Fakultas Ilmu Kesehatan Universitas PGRI Adi Buana Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/embrio.v17i2.10750

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Type 2 diabetes mellitus in adolescents has increased dramatically, with an incidence increasing from 9 to 18 cases per 100,000 per year in the last two decades. Extra Virgin Olive Oil (EVOO) has been shown to have a protective effect against diabetes through its bioactive components. This study aims to analyze the effect of EVOO supplementation on anthropometric parameters as an indicator of diabetes prevention in adolescent girls. This quasi-experimental study employed a pretest-posttest control-group design. The study population comprised all adolescent girls at SMKN 13 Malang, and subjects were selected through purposive sampling; 30 adolescent girls aged 15-18 years were included. Subjects were divided into an intervention group (n=15) who received 10ml/day of EVOO supplementation for 12 weeks and a control group (n=15) who received no treatment. The parameters measured included body weight, height, and waist circumference. The analysis used paired t-tests and Mann-Whitney tests. The results showed a significant decrease in body weight (p=0.000), BMI (p=0.000), and waist circumference (p=0.000) compared to the control group, which experienced an increase in body weight (0.5 kg) and waist circumference (0.233 cm). Still, there was no significant difference in height (p=0.539). In conclusion, EVOO supplementation is effective in reducing body weight and waist circumference in adolescent girls, demonstrating its potential as a preventive agent for diabetes mellitus through improving body composition.
The Role of Extra Virgin Olive Oil in Suppressing Oxidative Stress through Reducing Superoxide Dismutase Activity in Ratus Novergicus Preeclampsia Model Dwi Norma Retnaningrum; Wenny Rahmawati
Oksitosin : Jurnal Ilmiah Kebidanan Vol. 13 No. 1 (2026): OKSITOSIN : Jurnal Ilmiah Kebidanan
Publisher : Prodi D III Kebidanan Fakultas Ilmu Kesehatan Universitas Ibrahimy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35316/oksitosin.v13i1.8442

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Oxidative stress is a key factor in the pathophysiology of preeclampsia. Preeclampsia is characterized by hypertension and proteinuria. Superoxide Dismutase (SOD) will decrease when reactive oxygen species (ROS) are overproduced. Extra Virgin Olive Oil (EVOO) contains polyphenols and vitamin E, which are known to have strong antioxidant properties. The aim of this study was to assess how EVOO supplementation affects SOD activity in a rat model of preeclampsia (Rattus norvegicus). Pregnant rats were divided into a normal control group, a preeclamptic control group administered with L-NAME, and treatment groups receiving L-NAME and different doses of EVOO in a post-test control group design. Spectrophotometry was used to measure SOD activity. The results showed a significant difference between the SOD activity of the control and treatment groups (P value = 0.002). The optimal EVOO dose returned SOD activity to near normal control levels. In conclusion, EVOO supplementation shows potential as an adjunct therapy to reduce oxidative stress in preeclampsia by increasing SOD activity.
Suplementasi Extra Virgin Olive Oil (EVOO) Pada Ibu Hamil Untuk Mencegah Preeklamsia Wenny Rahmawati; Dwi Norma Retnaningrum
Jurnal Ners Vol. 9 No. 2 (2025): APRIL 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i2.46776

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In Indonesia, the leading cause of maternal mortality is still preeclampsia. The Indonesian Health Profile of 2023 recorded 412 cases of preeclampsia as the cause of maternal mortality. Until now, the only way to treat preeclampsia is to terminate the pregnancy. Although the cause of preeclampsia is not yet known, its pathophysiology is characterized by placental hypoperfusion and ischemia. Endothelial dysfunction, inflammatory pathways, the renin-angiotensin system (RAS), and oxidative stress are some of the factors that cause preeclampsia. Antioxidants such as extra virgin olive oil (EVOO) can help reduce oxidative stress. By examining blood pressure, urinary protein, platelets, and monocyte levels, this study attempts to determine the effectiveness of EVOO supplementation in preventing preeclampsia in pregnant women. This quasi-experimental study used a pretest and posttest design with a control group. As many as thirty pregnant women participated in this study, which was divided into treatment and control groups. During the week after delivery, the treatment group was given EVOO daily. The effectiveness of EVOO in preventing preeclampsia will be assessed by analyzing monitoring data using the T-Test. The results show that there is a significant difference in platelet levels between the treatment and control groups. EVOO helps prevent preeclampsia by stabilizing the platelet levels of pregnant women.