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All Journal Vis Vistalis AL KAUNIYAH E-Journal Widya Kesehatan dan Lingkungan Pro-Life Jurnal Mikologi Indonesia JFIOnline Journal of Microbial Systematics and Biotechnology Journal of Social Political Sciences (JSPS) Journal of Tropical Biodiversity DEDIKASI : Jurnal Pengabdian Kepada Masyarakat
Noverita
Universitas Nasional
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences

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Bioactivity of Fungi from the Thousand Islands Against Staphylococcus aureus and Escherichia coli Using Dilution Method Noverita Noverita; Samitri P. Debby
Journal of Tropical Biodiversity Vol 3 No 3 (2023): August 2023
Publisher : Universitas Nasional Jakarta

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Abstract

The rapid advancement of science and technology has brought numerous benefits to human life; however, it is unfortunate that this progress has not extensively tapped into one of Indonesia's abundant biological resources, which is fungi, especially marine fungi. This research was conducted to explore the antimicrobial potential of marine fungi isolated from the Thousand Islands against Staphylococcus aureus and Escherichia coli using the dilution method. The study aimed to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of the obtained isolates against the two test bacteria. The research comprised two phases: the collection of samples in the field, followed by the antimicrobial activity assay using the dilution method in the laboratory. The findings are expected to reveal several types of marine fungi from the Thousand Islands with antimicrobial capabilities that could be developed as alternative antibiotics to replace those that have lost their potency. The results of the study showed that out of the 10 tested marine fungi isolates, all of them exhibited inhibition against the growth of Staphylococcus aureus and Escherichia coli. The concentrations of 100% and 75% proved to be the most effective in inhibiting bacterial growth. The MIC of the tested marine fungi extracts was determined to be 25%. Moreover, five isolates of marine fungi demonstrated MBC against S. aureus and E. coli: S.KL5 isolate at concentrations of 75% and 50%, S.AL and S.KL1 isolates at concentrations of 100% and 50%, and S.MA2 and S.KL1 isolates at concentrations of 100% and 75%. The identified best isolates were found to belong to the species Penicillium sp. and Aspergillus niger .
The Ability of ᵝ-Glukan Pleurotus ostreatus in Biosorption of Lead Noverita, Noverita; Widyastuti, Anisa; Sukara, Endang; Ragamustari, Safendrri K.
Al-Kauniyah: Jurnal Biologi Vol. 19 No. 1 (2026): AL-KAUNIYAH JURNAL BIOLOGI
Publisher : Department of Biology, Faculty of Science and Technology, Syarif Hidayatullah State Islami

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/kauniyah.v19i1.40371

Abstract

The increase in toxic pollutants, such as the heavy metal lead (Pb²⁺), in aquatic environments is caused by anthropogenic activities and natural factors. Lead is difficult to degrade naturally, necessitating bioremediation methods, one of  involves biosorption agents. Macrofungi, such as Pleurotus ostreatus, have complex cell walls capable of absorbing heavy metals through β-glucan. This study evaluates the effectiveness of β-glucan from P. ostreatus in adsorbing lead. The biosorption mechanism is influenced by functional groups such as  hydroxyl (-OH), carboxyl (-COOH), and amine (-NH₂), as well as the coil structure of β-glucan, which affects binding site availability. Results show biosorption efficiency reaches 89–97%, with the highest at 97% at 25.64 mg/L and a contact time of 3 hours. Even after 1 hour, efficiency remains high (96%), indicating rapid and effective adsorption. FTIR analysis reveals changes in functional group structures after lead exposure, confirming the role of active groups in biosorption. Biosorption efficiency is also influenced by metal concentration, biomass amount and surface area, contact time, and biosorbent diffusion. These findings highlight the potential of β-glucan from P. ostreatus as a natural biosorbent for lead remediation in aquatic environments.
Edible Mushrooms in The Surroundings of Bangbayang Village, Situraja, Sumedang, West Java Qonitah, Tsabitah Athifah; Aryyanto, Muhammad Raul Alfadri; Suteja, Hardiansyah; Murti, Alena Puspa; Noverita, Noverita
Journal of Tropical Biodiversity Vol 4 No 1 (2023): December 2023
Publisher : Universitas Nasional Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59689/bio.v4i1.203

Abstract

Bangbayang is one of the villages located in the Situraja Subdistrict, Sumedang Regency, West Java. The natural conditions around the area are very cool with various types of plants, which also make it likely to find mushrooms, especially macro mushrooms that have the potential as food ingredients, but have not been reported. This study aims to inventory macro mushrooms with the potential as food ingredients in Bangbayang Village, Situraja Subdistrict, Sumedang Regency, West Java. The research method used is exploratory, and each sample of macro mushrooms obtained is observed based on the macroscopic characteristics of its fruiting body. The results of the study obtained a total of 12 species of macro mushrooms with the potential as food ingredients, namely; Agaricus campestris, Auricularia auricula, A. cornea, Boletus edulis, Cortinarius caperatus, Filoboletus manipularis, Lentinus sajor-caju, Lepista nuda, Russula rosea, Sarcomyxa edulis, Termitomyces clypeatus, and Tricholoma fraticum.
Macro Fungi Diversity in The Sanggabuana Mountain Area, Karawang Regency, Tegalwaru District, West Java Sumarouw, Achmad Alfio Dalish; Yafi, Ikhwal; Vansha, Fahriza Kemal; Noverita, Noverita
Journal of Tropical Biodiversity Vol 4 No 2 (2024): April 2024
Publisher : Universitas Nasional Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59689/bio.v4i2.216

Abstract

Sanggabuana Mountain is a mountain located within the territory of Karawang Regency. Administratively, the mountain is situated in Karawang Regency, Tegalwaru District, West Java. The height of the mountain is 1,291 meters above sea level (MDPL) and is the highest and only mountain in Karawang. The area has a high biodiversity, making it highly likely to find many macrofungi, especially macrofungi. This research was conducted to determine the diversity of macrofungi in the Sanggabuana Mountain area of Karawang Regency, Tegalwaru District, West Java. The type of research is exploratory and descriptive research, conducted on three observation routes; Route A (Cigentis), Route B (local plantations), and Route C (Kejayaan). The research results obtained a total of 23 species from 17 genera of macrofungi across the three observation routes, with the species diversity index in all three routes falling into the moderate diversity category. The highest encounter frequency of macrofungi on Route B was Ganoderma applanatum (23%), on Route A was Trametes sp (19%), and on Route C was Microporus xanthopus, Xylaria sp, and Inonotus sp (10%). The species dominance index on Route A falls into the high dominance category, while on Route B and C, it falls into the low dominance category.
Anti-Aging Potential of Moringa oleifera Bioactive Compounds: A Molecular Docking Approach Targeting Sirtuin Proteins Marthin, Jeffrey; Noverita, Noverita; Prasasty, Vivitri Dewi
Journal of Tropical Biodiversity Vol 5 No 2 (2025): April 2025
Publisher : Universitas Nasional Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59689/bio.v5i2.268

Abstract

Moringa oleifera has long been valued in traditional skincare, but its molecular interactions with key aging regulators remain poorly understood. This study elucidates the anti-aging potential of Moringa oleifera bioactive compounds through their modulation of sirtuin proteins (SIRT2, SIRT5, SIRT6), which govern genomic stability and oxidative stress responses. Using computational approaches, we performed molecular docking simulations (AutoDock Vina) on 20 bioactive compounds against sirtuin crystal structures from the Protein Data Bank. Comparative analysis with commercial anti-aging agents (niacinamide, AHA, ceramide) identified three Moringa compounds with superior binding affinities: rutin (-10.7 kcal/mol), quercetin (-8.9 kcal/mol), and chlorogenic acid (-7.9 kcal/mol), all outperforming niacinamide (-6.1 kcal/mol). SwissADME profiling confirmed their drug-like properties, including high oral bioavailability, blood-brain barrier penetration, and minimal toxicity risks. Mechanistically, these compounds demonstrated dual antioxidant and anti-inflammatory capacities, suggesting synergistic protection against oxidative damage and inflammation-driven aging. Our results position Moringa oleifera as a rich source of multitarget anti-aging candidates, combining computational validation with biological relevance to advance natural product-based interventions against cellular senescence.
Co-Authors Afifah Intan Kamila Ahmad Habib Nur Fikri Arum Lintang Dyah Lestari Aryyanto, Muhammad Raul Alfadri Astri Oktavina Atna Permana Batari Wahyu Pangesti Bhakti Nur Avianto Caroline Humaira Rifalina Rosyid Dennys Perdana Armanda E Sinaga Endang Sukara Endang Wahyu Ningsih Ernawati Sinaga Evi Nuraeni F Y Siti Fia Fadlun Fitria, Dinah Hana Kifayah Ikhsan Matondang Ilmi, Fauziah Marthin, Jeffrey Murti, Alena Puspa Nabilah Nabilah Nastiti Nastiti Nonon Saribanon Nuniek Ina Ratnaningtyas Nuraeni Ekowati Nyoman Ayu Ratmini Qonitah, Tsabitah Athifah Ragamustari, Safendrri K. Ratna Wati Ratna Wati Ratna Zahara Mahajarifar Ritchie Y.H L.T Samitri P. Debby Sara Pebrina Sri Lestari Sumarouw, Achmad Alfio Dalish Suprihatin Suprihatin Suteja, Hardiansyah Tatang M Setia Tatang Mitra Setia Vansha, Fahriza Kemal Vivitri Dewi Prasasty Widyastuti, Anisa Yafi, Ikhwal Yudistari Yudistari