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Dingse Pandiangan
Jurusan Biologi FMIPA Universitas Sam Ratulangi Manado
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Journal : pharmacon

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Efek Tepung Porang (Amorphophallus muelleri) yang Diberi Aluminium Sulfat Terhadap Fungsi Hati pada Tikus Winstar Diinduksi Asam Asetat Elvina Artha Nainggolan; Agnes Pingkan Lamia; Verina Putri Gloria Nainggolan; Frans Erwin Nicolaas Wantania; dingse Pandiangan
PHARMACON Vol. 11 No. 4 (2022): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

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Abstract

This study aims to determine the side effects of porang flour solution added with Aluminum Sulfate on AST (Aspartate Aminotransferase) as an indicator of liver function in Wistar rats. This research was conducted in a laboratory with a completely randomized design with 3 replications. Treatment of porang flour solution was added with Aluminum Sulfate 3% (w/v) then added 3 g of porang flour. The rats before treatment were induced by gastric ulcers of rats with 12.5% acetic acid for 3 days. Treatment of porang flour solution was carried out for 21 days with a sonde. Parameters observed were movement, morphology, body weight (growth) and AST (U/L) on 7, 14 and 21 days after treatment. Data analysis was performed using Statistica 6 at a 95% confidence level. The results showed that porang flour treatment mice had a much lower body weight, were healthy, agile and moved a lot, indicating that porang flour plus aluminum sulfate can be developed as an alternative diet food. AST levels after 21 days of treatment with porang flour solution decreased. The recovery of Wistar rats induced by 12.5% acetic acid wounds for 3 days can be healed after 21 days given a 2 mL porang flour solution by sonde based on the results of morphological observations and decreased levels of AST.
Co-Authors Adinata, Harni Seven Afiq Azizah Agnes Pingkan Lamia Anas Subarnas Anwar Sahid Della Saputri Dennie Heroike Rompas Eko Suyoko Elsania Pandahuki Elvina Artha Nainggolan Elvina Artha Nainggolan Elvis Umbu Katongu Retang Erly Marwan Fajar Hariadi FARHA DAPAS Febby E.F Kandou Febby E.F. Kandou Febby E.F. Kandou, Febby E.F. FEBBY KANDAU Feky R. Mantiri Frans Erwin Nicolaas Wantania Grace Yurico Bawole Henggu, Krisman Umbu Henny Lieke Rampe Henry Fonda Aritonang Herlyanti Yuliana Anggraeny Bawole Irfandi, Rizal Johanes, Albani Boutje Johanis Pelealu Johanis Pelealu Kandou, Febby Kandou, Febby E. Karyono - Leviane Jacklin Lotulung Linda Kakali Lisa Indried Pantilu Lutfiyah Maharani Maliangkay, Hendra Pratama Maningkas, Praise Maramis, Redway Truman Douglas Mardian Marhaenus J. Rumondor Maria Ballo Marina Silalahi Maudi Dian Tairas Meilany Feronika Durry Muhammad Nasir Muhammad Nur Nainggolan, Verina Putri Gloria Nancy Swanida H Malonda Nelson Nainggolan Nelson Nainggolan NELSON NAINGGOLAN Nelson Nainggolan NELSON NAINGGOLAN Nelson Nainggolan Nelson Nainggolan Nio Song Ai NISYAWATI NISYAWATI Nur Insani Amir Oki anggara Oratmangun, Kristina M. Parluhutan Siahaan Paulina Veronika Yolanda Lamleam Rama Riana Sitinjak Regina Hegemur Rizkita Rachmi Esyanti Rizkita Rahmi Esyanti - Roni Koneri Sahriah Rahim Sanriomi Sintaro Siti Fauziah Soares, Chrestina Noviyani Stery B. Oroh Stery B. Oroh, Stery B. Susan Mambu Susan Marlein Mambu Tobondo, Vanda Evanglin Van Gobel, Amelya Ramadhanty Verina Putri Gloria Nainggolan Verina Putri Gloria Nainggolan Wenny Tilaar Wenny Tilaar - Wulan Pingkan Julia Kaunang Kaunang Grad Dip Yudianto Ngaba Hamba Banju Yulianty Sanggelorang Yultrina Taghulihi Yunita Tamu Ina Zwingly C.J.G. Porajow