Imam Subadi
Department Of Physical And Rehabilitative Medicine, Faculty Of Medicine, Universitas Airlangga, Surabaya/ Dr. Soetomo General Academic Hospital, Surabaya

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THE EFFECTS OF PHYSICAL EXERCISES ON C-REACTIVE PROTEIN IN PATIENTS WITH POST ISCHEMIC STROKE Laswati, Hening; Andriana, Meisy; Subadi, Imam; Yuanita, Ida
Folia Medica Indonesiana Vol. 52 No. 3 (2016): JULY - SEPTEMBER 2016
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (62.5 KB) | DOI: 10.20473/fmi.v52i3.5449

Abstract

Several studies have recently highlighted the important role of physical exercise in regulation inflammatory status, but there is relatively little known about markers of inflammation levels after physical exercise in post ischemic stroke patients. The aims of this study to provide the effects of physical exercise using Partial Body-Weight Supported Treadmill Training –Audio Cues (PBWSTT-AC) and Traditional method on the level of inflammatory markers C-Reactive Protein (CRP). This study using pretest-postest control group design, 14 post ischemic stroke patients were randomized and allocate to two groups: Group1 (control group) received traditional walking exercise and group 2 received PBWSTT-AC. The walking exercise study were conducted for 20 minute 3 times a week for 12 sessions (4 weeks). Before and after 12 session of exercises, the serum levels of CRP were determined using immunoserology. All statistical test were carried out using SPSS 17 and statistical significance was set at p<0.05 for all analysis. The CRP levels between group were compared using Student t test or Mann-Whitney test. From multiple comparisons statistic result, no significant difference between groups (p=0.898), that seem in this study the levels of CRP of poststroke patients is not influenced by the Traditional training and PBWSTT-AC.  The conclusion of this study that both traditional method and PBWTT-AC in 4 weeks exercise training seem have no effect on CRP levels.
THE EXPRESSION OF TGF-1 AFTER LOW LEVEL LASER THERAPY IN INFLAMMATION ANIMAL MODEL Subadi, Imam; Wardhani, Indrayuni Lukitra; Andriati, Andriati
Folia Medica Indonesiana Vol. 53 No. 1 (2017): JANUARY - MARCH 2017
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (380.524 KB) | DOI: 10.20473/fmi.v53i1.5486

Abstract

Pain is the most common complaints in everyday practice. Pain is a clinical manifestation caused by stimuli due to potential tissue damage. Low level laser therapy (LLLT) has been used in reducing pain. One of indicator tissue healing is activation of transforming growth factor -b1(TGF-b1). Tissue healing will eliminate the pain. Do LLLT stimulate TGF-b1 expression? The objective of this study was to investigate the expression of TGF-b1 in low level laser therapy. Thirty male Wistar rats, body weight 250 – 300 gram, 3 month old, were divided into 3 groups, negative control (n=10), positive control (n=10) and treatment groups (n=10). The positive control and treatment groups were injected with Complete's Freund Adjuvant (CFA) 100 mL at left footpad. The treatment group treated with low level laser therapy Lasermed type 2100 wavelength 905 nm, out power 25-500 mW, dose 1 joule/cm2;5 times with interval 24 hours on left footpad. Samples were taken from the skin of footpad and immunohistochemical examination with monoclonal antibody anti- TGF-b1. Calculations carried out on brown reaction in macrophage cell. Data were analyzed using the Games Howell with SPSS 17. There were significant differences in the expression of TGF-b1 in treatment group (15.8±3.1) compared with the positive control group (3.9±1.1) and negative control group (4.6±2.1). There were no significant differences between expression TGF-b1 in positive control group and negative control group. In conclusion, low level laser therapy increased the expression of TGF-b1.
Early Application of Neuromuscular Electrical Stimulation Prevents Excessive Muscle Wasting in Critically Ill Patients in the Intensive Care Unit Utama Hutapea, Johannes Diandra Indra; Subadi, Imam; Arfianti, Lydia; Semedi, Bambang Pujo; Melaniani, Soenarnatalina
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol. 14 No. 2 (2025): October 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v14i2.2025.77-83

Abstract

Background: Intensive Care Unit-Acquired Weakness (ICU-AW) is a common neuromuscular complication in critically ill patients, leading to muscle atrophy, prolonged mechanical ventilation and impaired functional recovery. Effective rehabilitation strategies play crucial role in maintaining muscle strength. Neuromuscular electrical stimulation (NMES) had shown potential in preserving quadriceps femoris muscle thickness. This study aimed to examine the effect of NMES to quadriceps femoris muscle thickness in patient with ICU-AW.Methods: Patients that stayed in ICU more than 48 hours and used mechanical ventilation for at least 24 hours enrolled in one-group pretest-posttest design. Neuromuscular electrical stimulation applied to bilateral quadriceps femoris for 30 minutes daily over five consecutive days. Bilateral quadriceps femoris muscle thickness were assessed with USG day before and after therapy.Results: Twenty ICU-AW patients were enrolled from December 2023 to June 2024, and 13 of them completed the study. There were no significant changes in the thickness of the right and left quadriceps femoris muscle before and after 5-days of NMES therapy (p = 0.910 and p = 0.519, respectively). However, we preserved less than 5% decreased of muscle thickness.Conclusions: Early 5-days of NMES therapy did not increase quadriceps femoris muscle thickness but effectively prevented further muscle degradation in ICU-AW patients. The potential benefits of rehabilitation therapy in ICU-AW patients should be further explored in future studies with controlled indicators and larger sample sizes.
Anticipatory Balance in Athletes Cerebral Palsy After 6-Month Intervention of Proprioceptive Neuromuscular Facilitation Stretching Techniques Martino, Nieko Caesar Agung; Subadi, Imam; Satyawati, Rwahita; Indriani, Diah
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol. 14 No. 2 (2025): October 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v14i2.2025.84-91

Abstract

Background: The effect of Proprioceptive Neuromuscular Facilitation (PNF) stretching, in addition to standard stretching, improves anticipatory balance in athletes with Cerebral Palsy (CP). We aimed to analyze the effects of PNF stretching to standard training over 4 weeks on anticipatory balance in Cerebral Palsy athletes at 6-month post-intervention evaluation. Methods: The subjects of this study are 24 athletes with Cerebral Palsy at the Indonesian National Paralympic Committee (NPC) training facility. Subjects divided into the treatment group (n = 12) received standard stretching exercises along with PNF stretching, and the control group (n = 12) performed only standard stretching exercises. Both groups received intervention 3 times per week for 4 weeks and evaluation 6 months post-intervention. Y balance tests (YBT) were measured in three directions: anterior (A), posterolateral (PL), and posteromedial (PM), pre- and post-intervention.Results: There was significant improvement of YBT in the treatment group after 4 weeks of intervention. For the right and left limbs, marked increases were observed in all directions (p < 0.05). No significant improvements in YBT were observed at 6 months post-intervention in all directions (p > 0.05).Conclusions: Significant improvements in the Y Balance Test were observed after 4 weeks, but no differences between the two groups at the 6-month evaluation. These findings suggest that while short-term gains in dynamic stability are achievable with PNF, sustained benefits require ongoing reinforcement to maintain neuromuscular adaptations over time.
PROFILE OF BRAIN INJURY PATIENTS WITH COVID-19 INFECTION AT DR. SOETOMO HOSPITAL SURABAYA FOR THE PERIOD 2020 TO 2022 Mulyana, Darian; Turchan, Agus; Subadi , Imam; Apriawan, Tedy
Journal of Social Research Vol. 3 No. 2 (2024): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v3i2.1928

Abstract

In 2019, a previously unidentified coronavirus was named COVID-19. This virus can infect everyone without exception, including brain injury patients. Because this virus is relatively new, there have not been many studies examining the interaction of COVID-19 with brain injury. The purpose of this study was to examine the profile of brain injury patients with COVID-19 at Dr. Soetomo Hospital. Method This study was conducted with a descriptive observational method with a retrospective approach. The data taken came from the medical records of Dr. Soetomo Hospital. The results of 56 brain injury patients with COVID-19, the majority of whom were male, most of whom were in the age range of 40 – 59 years, mild brain injury cases were the most dominant, the average length of patient stay was 16.4 days and patient mortality was 30.4%.