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All Journal BALI MEDICAL JOURNAL (BMJ) Jurnal VOK@SINDO Folia Medica Indonesiana Jurnal NERS MNJ (Malang Neurology Journal) Health Notions Journal Orthopaedi and Traumatology Surabaya (JOINTS) SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL Majalah Biomorfologi (Biomorphology Journal) Indian Journal of Forensic Medicine & Toxicology Journal of Social Research Journal of Pain, Vertigo and Headache

Imam Subadi

Department Of Physical And Rehabilitative Medicine, Faculty Of Medicine, Universitas Airlangga, Surabaya/ Dr. Soetomo General Academic Hospital, Surabaya

Author-ID : 3400664

Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Ekspresi HSP 70 dan Ekspresi Reseptor Opioid Mu pada Penurunan Nyeri Terapi Bekam Basah Imam Subadi; Hening Laswati; Harjanto JM
Jurnal Ners Vol. 11 No. 1 (2016): April 2016
Publisher : Universitas Airlangga

Introduction: Wet cupping therapy widely used to reduce the pain, but the mechanisms of pain reduction on wet cuppig therapy is unclear. Stretching and punctures on wet cupping therapy cause stress on the cell. Cells that are stressed express HSP 70 and mu opioid receptors. This study aims to prove the correlation increased expression of HSP 70 and an increase in post-mu opioid receptor wet cupping therapy.Methods: The study is an experimental research design with randomized control group post-test only design. Twenty-four rats type Wistar (Rattus norvegicus) were randomly divided into three groups, each consisting of eight mice are negative control group (normal mice), group induction of pain with Complete Freund's Adjuvant (CFA) alone (positive control) and group by induction of pain and bekam basah therapy (10 puncture and negative pressure: - 200 mmHg, 5 minutes). Samples were taken from the skin and immunohistochemical examination with the monoclonal antibody anti mu opioid receptors. The reaction time pain threshold measured using a hot-plate. Data were analyzed by oneway ANOVA and Pearson Correlation using SPSS version 17.Results: This study shows that there is an increased expression of HSP 70 (P <0.05) compared to the positive control group (p <0.05) and increased expression of mu opioid receptors ( p <0.05) compared to the positive control group (p <0.05). There is an increased pain threshold reaction time (p <0.05) compared to the positive controls (11.78 ± 3.56). There is a correlation between an increased expression of HSP 70 and an increase in mu opioid receptor (β = 0893; p = 0.000) and there was a correlation between the increase in mu opioid receptor with a reaction time of pain threshold (β = 0713; p = 0.002).Discussion: Wet cupping therapy increase HSP 70 expression, opioid mu receptor, and decrease pain level.

Effect of Aerobic Exercise on Brain-derived Neurotrophic Factor (BDNF) Serum Level in Stroke Subjects with Cognitive Function Impairment Vanydia Aisyah; Subagyo Subagyo; Imam Subadi
Surabaya Physical Medicine and Rehabilitation Journal Vol. 2 No. 2 (2020): SPMRJ, AGUSTUS 2020
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v2i2.17669

Background: Cognitive impairment is the most frequent complication of stroke. However, erobic exercise is considered to have potential effect in inhibiting the post-stroke cognitive degradation and increasing cognitive performance through neuroplasticity-influenced long term potentiation in hippocampus.Aim: To determine the effect of aerobic exercise on brain-derived neurotrophic factor (BDNF) serum level in stroke subjects with cognitive function impairment.Material and Methods: Experimental pre-post study on sub-acute stroke male and female, 12 subjects on each group. Intervention group given standard therapy and aerobic exercise using static cycle. Control group treated with standard therapy 30 minutes/session 3x/week, for 6 weeks. Parameter being evaluated was BDNF serum level.Result: No significant difference (p=0.21) in BDNF serum level in both control group (246.03±40.81 pg/ml) and intervention group (280.98±73.53 pg/ml) after treated with treatment. Although there was a significant increase of BDNF serum level in the intervention group (p<0.001) with pre-intervention mean value of 1.96±60.69 pg/ml and post-intervention mean value of 280.98±73.53 pg/ml. Similar to the intervention group, there was a significant increase in BDNF serum level (p<0,001) in control group, with pre-intervention mean value of 136.39±76.32 pg/ml and post-intervention mean value of 246.03±40.81 pg/ml.Conclusion: No significant difference in BDNF serum levels in intervention group after aerobic exercise program with a static cycle and standard therapy 3x/week for 6 weeks, when compared to the control group that only received standard therapy, although both control and intervention groups showed significant difference before and after the intervention.

The Influence of Elastic Taping on Dynamic Muscular Control (Dynamic Control Ratio) Evertor-Invertor Ankle in Type 2 Diabetes Mellitus Male with Complications of Peripheral Neuropathy Yuli Indah Kurnia; Imam Subadi; I Putu Alit Pawana; Sony Wibisono
Surabaya Physical Medicine and Rehabilitation Journal Vol. 2 No. 2 (2020): SPMRJ, AGUSTUS 2020
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v2i2.17673

Background: Type 2 Diabetes Mellitus (DM) with Peripheral Neuropathy often have impared control of muscle strength that increases the risk of fall. Elastic taping (ET) is a special elastic band that can stretch up to 140% and could facilitate muscle contraction.Aim: To prove the influence of ET on the dynamic muscular control balance between evertor and invertor muscles of the ankle in type 2 DM male with peripheral neuropathy.Material and methods: This study used a pre-post one grup study, with10 type 2 DM male with peripheral neuropathy. All subjects were examined for ankle evertor-invertor dynamic control ratio (DCR) with isokinetic dynamometer at 600/sec and 1200/sec before elastic taping (ET), 30 minutes after ET, at the third day of ET aplication and 3 days after ET was released. Elastic taping was applied with functional tehniques on the both ankles.Result: There were no significant differences between with and without the application of KT in the ankle evertor-invertor DCR in both side. The p value were same in both sides, at 600/sec after 30 minute ET (p=0.72), at the third day of ET aplication (p=0,24), 3 days after released ET (p= 0,88) and at 1200/sec after 30 minute ET (p=0,17).Conclusion: Elastic taping did not improve the ankle evertor-invertor DCR in type 2 DM male patients with peripheral neuropathy.

Non-Pharmacological Balance Therapy on Diabetic Peripheral Neuropathy Patients with Balance Disorders Jeremy Nicolas Sibarani; Kristanti Wanito Wigati; Imam Subadi
Surabaya Physical Medicine and Rehabilitation Journal Vol. 4 No. 1 (2022): SPMRJ, FEBRUARY 2022
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v4i1.24982

ABSTRACTBackground: Patients with diabetic peripheral neuropathy (DPN) suffers from propioceptive ability and mobility disturbance which can potentially affects balance. There are various balance therapy options for DPN patients. The purpose of this study was to determine the effectiveness of various non-pharmacological therapies (surgery, traditional medicine, exercise and assistive devices) in DPN patients with balance disorders.Aim(s): To determine the effectiveness of non-pharmacological balance therapy in people with diabetic peripheral neuropathyMaterial and methods: A systematic review was conducted using randomized controlled trial study articles found using PICO characteristics in ScienceDirect and PubMed in the last 10 years. All articles were selected based on PRISMA and descriptive analysis was carried out on the selected articles.Result: Significant balance improvement found in traditional Thai massage, physical exercise therapy, assistive device therapy with whole-body vibration, and assistive device therapy with electrical stimulation. Surgical therapy with unilateral nerve decompression did not provide a significant measurable balance improvement.Conclusions: Physical exercise therapy, traditional Thai foot massage, WBV and electrical stimulation therapy (with the exception of TENS on the knee) significantly improve balance. Meanwhile, unilateral nerve decompression surgical therapy did not improve the balance significantly.

Effect of Anodal Transcranial Direct Current Stimulation to Flexor Digitorum Superficialis Muscle Activities in Stroke Subjects Ana Mursyida; Reni Hendrarati Masduchi; Imam Subadi
Surabaya Physical Medicine and Rehabilitation Journal Vol. 4 No. 1 (2022): SPMRJ, FEBRUARY 2022
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/spmrj.v4i1.25119

Background: Stroke is the main causes of upper extremity weakness that may affect physicalindependency resulting in long-term disability. Previous studies showed that A-tDCS can improve neurological damage. A-tDCS causes depolarization and inducesbrainsynapticplasticity in strokesubjects.Aim: To analyze the effect of Anodal-tDCS to the flexor digitorum superficialis muscles activities in stroke subjects.Material and Methods: This experimental study was conducted from April to September 2020. Eightpatients who suffered first attack ischemic stroke, aged 40 to 70 years old, were recruited from PMR out patient clinic at Dr.Soetomo General Hospital Surabaya. Subjects were randomized in to experimental and control group. The control group was given occupational therapy for 30 minutes, while the experimental group was given A-tDCS with intensity 2 mA for 20 minutes and occupational therapy for 30 minutes in 5 consecutive days. Measurement of FDS muscle activities using sEMG were performed before and after interventionin both groups. Results: There was an increase of FDS muscles activities after treatment incontrol group (p=0,048) while there was no similar result in treatment group (p=0,188). Thechangeofmuscles activities was notdifferent betweengroups(p=0,974).Conclusion: tDCS provides no significant benefit in terms of muscle activities in patients with stroke. Small number of samples and other several factors might limit the significancy of current study. Further study is needed to determine the benefit of A-tDCS as a rehabilitation modality in patient with stroke.

MEDICAL REHABILITATION MANAGEMENT OF CARPAL TUNNEL SYNDROME Imam Subadi; Hanik Hidayati; Fidiana Fidiana; Nur Sulastri
Journal of Pain, Headache and Vertigo Vol. 2 No. 2 (2021): September
Publisher : Journal of Pain, Headache and Vertigo

Carpal tunnel syndrome (CTS), the most common entrapment neuropathy in the upper extrimity, is a clinical syndrome characterized by a tingling sensation, numbness, pain, or weakness in the hand and wrist radiating up to the arm. This condition is a major cause of absenteeism, reduced productivity, and financial loss among various neuropathy due to median nerve compression. This paper, medical rehabilitation of CTS is viewed. Medical rehabilitation of CTS aimed to reduce pain, reduce clamping of the carpal tunnel, sensory and motor reeducation so that hand function improves and can perform activities of daily living. Treatment options can be given includes exercise therapy, ultrasound diathermy, low level laser therapy (LLLT), and shock wave therapy (SWT).

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2021.002.02.3

PATTERN OF RHEUMATIC DISEASES IN THE DIVISION OF RHEUMATOLOGY, DR. SOETOMO GENERAL ACADEMIC HOSPITAL, SURABAYA, INDONESIA, BETWEEN NOVEMBER 2021 AND MARCH 2022 Afifur Rafi Hilmi Aziz; Yuliasih; Imam Subadi
Majalah Biomorfologi Vol. 33 No. 2 (2023): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v33i2.2023.82-91

Highlights: Rheumatic diseases, like many others, are often misdiagnosed and treated late in life, resulting in the increase of rheumatic diseases incidence. Gender, age, level of education, and occupation all play crucial roles in the onset of rheumatic disorders. Abstract Background: The epidemiology of rheumatic diseases plays an important role in the spread of rheumatic diseases worldwide. Epidemiology data of rheumatology diseases in Dr. Soetomo General Academic Hospital remains unclear as there are some problems such as rheumatic drug depletion and imperfect medical recording. Â Objective: This study aimed to analyze the pattern of rheumatic diseases at the Division of Rheumatology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Â Material and Method: This prospective descriptive study used secondary data from medical records between November 2021 and March 2022 at the Division of Rheumatology, Dr. Soetomo General Academic Hospital. The variables of this study were gender, age, occupation, education level, disease duration, and clinical manifestations. Results: Secondary data was provided by 109 patients in this study. Gender was dominated by women as much as 96 (88%), age was dominated by age groups 26-35 years and 46-55 years, each as much as 26 (23.8%), educational level was dominated by senior high school as much as 24 (22%), and employment was dominated by housewives as much as 39 (35.7%) in the Divison of Rheumatology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Based on disease incidence, 42 patients (38.5%) had systemic lupus erythematosus, and 38 patients (34.8%) had ankylosing spondylitis. Conclusion: Rheumatology patients at Dr. Soetomo General Academic Hospital Surabaya are predominantly female, aged 26-55, with senior high school education. The diseases mostly affect housewives and have a higher frequency of systemic lupus erythematosus and ankylosing spondylitis.

BARTHEL INDEX SCORE IN STROKE PATIENTS INCREASES AFTER UNDERGOING MEDICAL REHABILITATION Maharani Ganing, Sirly Nabireta; Subadi, Imam; Sugianto, Paulus
Folia Medica Indonesiana Vol. 51 No. 4 (2015): Oktober - December 2015
Publisher : Universitas Airlangga

Stroke is the leading cause of death among Indonesian people over the age of five years, comprising 15.4% of all deaths, with a mortality rate of 99/100 000, and the number of disability is 685/100 000. Medical rehabilitation has an effect in improving functional status of patients with stroke, especially if it is done intensively in the first 6 months after stroke attack. Measurement of functional status is commonly used in clinic, including in Dr. Soetomo Hospital. However, no study had been conducted in measuring functional status using Barthel Index in Surabaya. Therefore, this study identified the difference of the functional status of stroke patients before and after undergoing medical rehabilitation. The study used an experimental method with pre and post design with total sampling. The samples were 47 stroke patients in Dr. Soetomo Hospital, Surabaya. Data were obtained from March - April 2014 using Barthel Index. Data analysis used Wilcoxon Sign Rank test, including the distribution of each variable, which showed signification value of <0.05. This study concluded that Barthel Index score increases after undergoing medical rehabilitation.

COMPARISON EFFECT OF CV 12, ST 36 AND ST 40 EA ON SHORT TERM ENERGY BALANCE REGULATION IN HIGH FAT DIET RAT Rejeki, Purwo Sri; Harjanto, Harjanto; Argarini, Raden; Subadi, Imam
Folia Medica Indonesiana Vol. 52 No. 3 (2016): JULY - SEPTEMBER 2016
Publisher : Universitas Airlangga

The aim of this study was to determine the comparative effects of EA (EA) on the CV12, ST36 and ST40 to weight gain prevention over the short-term regulation of energy balance. The study was conducted with a completely randomized design. Rats were divided into five groups: negative control group (no treatment, n=5), positive control (sham EA/back, n=5), EA CV 12 (n=6), EA ST 36 (n=6) and EA ST 40 (n=7). Rats were exposed to high-fat diet for two weeks and EA was simultaneously performed once daily, five days a week for two weeks with 2 Hz, for 10 minutes with continuous wave. Body weight, BMI, front limb circumference and rear were measured during study. Levels of blood glucose, cholesterol, triglycerides, LDL and HDL were measured at the end of the study; which reflects the short-term regulation of energy homeostasis. For weight loss, EA CV12, ST36 and ST40 group have lost weight significantly compared to the negative and positive control group. The ST40 group has a significant decrease than ST36 and CV12. The most significant decrease in BMI found in the ST40 group. EA did not affect blood glucose levels, but modulated blood lipid profile. In ST 40 group there was a significant decrease in cholesterol, LDL and triglycerides. EA at point ST 40 is potential in preventing increased body weight and BMI in rats exposed to high-fat diet compared to the CV 12 and ST 36. ST 40 is a point with a potential of lowering LDL and triglycerides serum so that it can play a role in the short term regulation of energy homeostasis but also in the prevention of dyslipidemia.

Co-Authors Afifur Rafi Hilmi Aziz Ahmad Arif Ridha Ana Mursyida Andre Triade Desnantyo Andriana, RA Meisy Andriati Andriati Andriati Andriati Benni Azhari Damayanti Tinduh Dewi Septiani M K Sintia Diah Indriani Fauza Alfin Fidiana Fiequria Asri Ersyana Hanik Hidayati HARJANTO HARJANTO Harjanto JM Harjanto JM Hening Laswati Putra Islam, Mohamad Saiful J. A. Pangkahila Jeremy Nicolas Sibarani Kusumawardhany Airlangga Rijanti Langgeng Gunariadi Lydia Arfianti Mangestuti Agil Martino, Nieko Caesar Agung Masduchi, Reni Hendrarati Mulyana, Darian Nugraheni S. Nuniek Nuniek Nugraheni Nur Sulastri Nur Sulastri Patricia Maria Kurniawati Paulus Sugianto, Paulus Pawana, I Putu Alit Poerwandari, Dewi Putri, Nila Novia Raden Argarini Rejeki, Purwo Sri Retno Widyowati Rwahita Satyawati Dharmanta Semedi, Bambang Pujo Sirly Nabireta Maharani Ganing, Sirly Nabireta Soenarnatalina Melaniani Soenarnatalina Melaniani Sony Wibisono Subagyo Subagyo Tedy Apriawan Turchan, Agus Utama Hutapea, Johannes Diandra Indra Vanydia Aisyah Wardhani, Indrayuni Lukitra Wigati, Kristanti Wanito Yuanita, Ida Yuli Indah Kurnia Yuliasih Yuliasih

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