Article Per Year (5 Year)
p-Index From 2021 - 2026
1.325
P-Index
This Author published in this journals
All Journal Majalah Kedokteran Bandung Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Althea Medical Journal Jurnal Farmasi Klinik Indonesia Global Medical and Health Communication Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Jurnal MedScientiae Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD)
Hikmat Permana
Department Of Internal Medicine, Faculty Of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital Bandung,
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 17 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search
Journal : Althea Medical Journal

 1 
Anti-hyperglycemic Effect of Psidium guajava Leaf Infusion Zartiana, Rizda Nurul; Surialaga, Samsudin; Permana, Hikmat
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (492.213 KB)

Abstract

Background: Prevalence of diabetes mellitus is estimated to increase annually. Numerous people use traditional medicine, such as the Poidium guajava leaf to prevent this disease. This study aimed to analyse the effect of Psidium guajava leaf to inhibit glucose absorption in intestine epithelial membrane of wistar rats.Methods: This laboratory experimental study used 5 wistar rats as subjects in the Laboratory of Biochemistry at Padjadjaran University from 10−26 October 2012. All rats were given three solutions by in situ perfusionmethod. The first was 25 ml 3.0 X 10-3 M glucose solution, the second was 25 ml 3.0 X 10-3 M glucose solution with 1 ml Psidium guajava infusion added, and the third was 25 ml 3.0 X 10-3 M glucose solution.The sample from each solution was taken five times at 0, 15, 30, 45, and 60 minutes after the solutions were given. The spectrophotometer was to quantify the concentration of glucose from the samples. Data were analyzed using Friedman and Wilcoxon test.Results:The means of glucose concentration for each solution from the first solution to the third were 6.126 mg/dl, 2.447 mg/dl, and 5.345 mg/dl. The probability value showed significant difference between the first and second solutions (p ≤ 0.05).Conclusions: Psidium guajava leaf infusion can inhibit glucose absorption in wistar rat intestine and the effect is reversible. [AMJ.2015;2(4):546–9] DOI: 10.15850/amj.v2n4.508
Metabolic Syndrome Components and Nutritional Status among Hypertensive Outpatiens at Dr. Hasan Sadikin General Hospital Bandung Mirandus, Lira; Permana, Hikmat; Fatimah, Siti Nur
Althea Medical Journal Vol 3, No 3 (2016)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (135.873 KB)

Abstract

Background: Metabolic syndrome and overnutritional status (overweight and obesity) are examples of determinants that can give rise to hypertension, so the three diseases are correlated with each other. This study aimed to reveal metabolic syndrome components and nutritional status among hypertensive outpatients.Methods: This study involved 44 hypertensive outpatients who visited the Nephrology and Hypertension Clinic of Dr. Hasan Sadikin Hospital, Bandung in September to October 2013. Anthropometric and blood pressure measurements, anamnesis, and medical record data collection were carried out to describe the patient’s metabolic syndrome components by using International Diabetes Federation criteria on South Asian people and nutritional status by WHO classification in Asian people.Results: Among respondents, 25 (57%) had abdominal obesity, 14 (32%) had hypertrygliceridemias, 14 (32%) had low HDL cholestrol, 19 (43%) were taking lipid-lowering medications, 20 (45 %) had high level of fasting blood glucose, 21 (48%) had been diagnosed as mellitus type 2, 15 (34%) had high blood pressure, 40 (91%) were taking antihypertensive medications, 19 (43%) had metabolic syndrome, and 31 (70%) were overweight or obese.Conclusions: Less than a half of the respondents meet the metabolic syndrome criteria and over two third of them are at overnutrition state (overweight or obesity). [AMJ.2016;3(3):476–80]DOI: 10.15850/amj.v3n3.862 
Anti-hyperglycemic Effect of Psidium guajava Leaf Infusion Rizda Nurul Zartiana; Samsudin Surialaga; Hikmat Permana
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (492.213 KB)

Abstract

Background: Prevalence of diabetes mellitus is estimated to increase annually. Numerous people use traditional medicine, such as the Poidium guajava leaf to prevent this disease. This study aimed to analyse the effect of Psidium guajava leaf to inhibit glucose absorption in intestine epithelial membrane of wistar rats.Methods: This laboratory experimental study used 5 wistar rats as subjects in the Laboratory of Biochemistry at Padjadjaran University from 10−26 October 2012. All rats were given three solutions by in situ perfusionmethod. The first was 25 ml 3.0 X 10-3 M glucose solution, the second was 25 ml 3.0 X 10-3 M glucose solution with 1 ml Psidium guajava infusion added, and the third was 25 ml 3.0 X 10-3 M glucose solution.The sample from each solution was taken five times at 0, 15, 30, 45, and 60 minutes after the solutions were given. The spectrophotometer was to quantify the concentration of glucose from the samples. Data were analyzed using Friedman and Wilcoxon test.Results:The means of glucose concentration for each solution from the first solution to the third were 6.126 mg/dl, 2.447 mg/dl, and 5.345 mg/dl. The probability value showed significant difference between the first and second solutions (p ≤ 0.05).Conclusions: Psidium guajava leaf infusion can inhibit glucose absorption in wistar rat intestine and the effect is reversible. [AMJ.2015;2(4):546–9] DOI: 10.15850/amj.v2n4.508
Metabolic Syndrome Components and Nutritional Status among Hypertensive Outpatiens at Dr. Hasan Sadikin General Hospital Bandung Lira Mirandus; Hikmat Permana; Siti Nur Fatimah
Althea Medical Journal Vol 3, No 3 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (124.928 KB)

Abstract

Background: Metabolic syndrome and overnutritional status (overweight and obesity) are examples of determinants that can give rise to hypertension, so the three diseases are correlated with each other. This study aimed to reveal metabolic syndrome components and nutritional status among hypertensive outpatients.Methods: This study involved 44 hypertensive outpatients who visited the Nephrology and Hypertension Clinic of Dr. Hasan Sadikin Hospital, Bandung in September to October 2013. Anthropometric and blood pressure measurements, anamnesis, and medical record data collection were carried out to describe the patient’s metabolic syndrome components by using International Diabetes Federation criteria on South Asian people and nutritional status by WHO classification in Asian people.Results: Among respondents, 25 (57%) had abdominal obesity, 14 (32%) had hypertrygliceridemias, 14 (32%) had low HDL cholestrol, 19 (43%) were taking lipid-lowering medications, 20 (45 %) had high level of fasting blood glucose, 21 (48%) had been diagnosed as mellitus type 2, 15 (34%) had high blood pressure, 40 (91%) were taking antihypertensive medications, 19 (43%) had metabolic syndrome, and 31 (70%) were overweight or obese.Conclusions: Less than a half of the respondents meet the metabolic syndrome criteria and over two third of them are at overnutrition state (overweight or obesity). [AMJ.2016;3(3):476–80]DOI: 10.15850/amj.v3n3.862 
Characteristics and Clinical Outcomes of COVID-19 Patients with Hyperglycemia: Retrospective Cohort Study from a COVID-19 Referral Hospital, Bandung, Indonesia Permana, Hikmat; Ikhsanawati, Annisa; Susandi, Evan; Soetedjo, Nanny Natalia Mulyani; Alisjahbana, Bachti
Althea Medical Journal Vol 10, No 4 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v10n4.3111

Abstract

Background: COVID-19 often causes severe complications in patients with metabolic disorders such as diabetes mellitus. Conversely, inflammation caused by infection may also trigger insulin resistance, resulting in hyperglycemia and is related to the disease severity. This study aimed to describe the characteristics and clinical outcomes of COVID-19 patients with hyperglycemia at one of the COVID-19 referral hospitals in Bandung, Indonesia.Methods: This retrospective cohort study used secondary data from medical records of COVID-19 patients admitted to Dr. Hasan Sadikin General Hospital Bandung, Indonesia from March 2020 to March 2021. This study included all patients with confirmed COVID-19, aged >18 years, and had at least one blood glucose test at admission. Patients were grouped based on three possible types of hyperglycemia, namely diabetes mellitus, reactive hyperglycemia, and steroid-induced hyperglycemia; then their characteristics and disease outcomes were compared. Results: This study identified 1,114 patients’ medical records and included 1,013 data in the analysis. Hyperglycemia occurred in 45.1% of COVID-19 patients. The most common hyperglycemia types were diabetes mellitus (55.7%), reactive hyperglycemia (37.4%), and steroid-induced hyperglycemia (7%). The steroid-induced hyperglycemia group had similar characteristics as the diabetes group. The reactive hyperglycemia group exhibited a metabolic syndrome pattern resembling pre-diabetic conditions. The highest rates of severe disease and mortality were seen in the steroid-induced hyperglycemia group, followed by the diabetes group.Conclusions: There is an elevated prevalence of hyperglycemia in COVID-19 patients with diabetes. The steroid-induced hyperglycemia group has the most unfavorable outcomes. These observations emphasize the importance of identifying hyperglycemic conditions to improve management and outcomes.
Co-Authors Alfaqeeh, Mohammed Ame Suciati Setiawan Annisa Ikhsanawati, Annisa Augusta Y. L. Arifin Bachti Alisjahbana Davin Takaryanto Della Aprilliana Suherlim* Elin Yulinah Gaga Irawan Nugraha Guntur Darmawan Hasrayati Agustina I Ketut Adnyana Khairinisa, Miski Aghnia Kristina Wiharjo Kusumawati, Maya Leonardo Lubis Lira Mirandus Loe, Luse Marshell Tendean Miftahurachman Miftahurachman, Miftahurachman Mirandus, Lira Muhammad Iman Pratama Putra Nanny N. M. Soetedjo Nanny Natalia M Soetedjo Nanny Natalia Mulyani Soetedjo Nanny Natalia Mulyani Soetedjo Nanny Natalia. M Soetedjo Nenny Agustanti Noormartany Primal Sudjana Ritonga, Ervita Rizda Nurul Zartiana Rizda Nurul Zartiana, Rizda Nurul Rudi Supriyadi Samsudin Surialaga Siti Nur Fatimah Siti Nur Fatimah Sri Hartini K. S. Kariadi Stephanus Kristianto Witono Sudigdo Adi Susandi, Evan Sylvia Rachmayati Yohana Azhar Yumilia Hoo