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All Journal JOURNAL OF COASTAL DEVELOPMENT ILMU KELAUTAN: Indonesian Journal of Marine Sciences Agrointek Sains Natural: Journal of Biology and Chemistry To Maega: Jurnal Pengabdian Masyarakat Journal of Functional Food and Nutraceutical Journal of Digital Marketing and Halal Industry Prima Abdika: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat (ABDIRA) Berkala Penelitian Hayati Magistrorum et Scholarium: Jurnal Pengabdian Masyarakat Science Technology and Management Journal (STMJ)
Paulus Damar Bayu Murti
Department Of Food Technology, Faculty Of Science And Technology, Karangturi National University, Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Social Sciences Other

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Journal : JOURNAL OF COASTAL DEVELOPMENT

 1 
ANTIBACTERIAL ACTIVITY OF BACTERIAL SYMBIONT OF SOFT CORAL Lobophytum sp. AGAINST MDR BACTERIA Escherichia coli and Staphyllococcus aureus Paulus Damar Bayu Murti; Ocky Karna Radjasa
JOURNAL OF COASTAL DEVELOPMENT Vol 15, No 3 (2012): Volume 15, Number 3, Year 2012
Publisher : JOURNAL OF COASTAL DEVELOPMENT

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Abstract

The improper and uncontrolled uses of antibiotics againts pathogenic bacteria have resulted in the occurrence of Multi Drug Resistant (MDR) strains. There is now an urgency to find alternative antibiotics to combat the MDR strains especially Escherichia coli and Staphyllococcus aureus. Soft coral associated microorganisms are among the most interesting and promising marine natural product sources which produce polyketide and non ribosomal peptide products with various biological activities. In this study, marine bacteria were isolated from soft coral Lobophytum sp. collected from North Java Sea, and were screened for antibacterial activity against MDR strains. One out of 13 bacterial isolates were succesfully screened and were found to be active against both MDR strains, in which isolate LBTGA2 was active against resistant strains E. coli and against resistant S. aureus, respectively. The active isolate also amplified PKS (Polyketide Synthases) gene fragments necessary for the biosynthesis  of polyketides. The molecular identification based on partial 16S DNA nukleotide sequences indicates that the active isolate was closely related to Paenibacillus campinasensis.
Co-Authors A'liyatur Rosyidah Ahmad Nugroho Ahmad Nugroho Angela Putri Hartono Anggara Mahardika Anggara Mahardika Anggara Mahardika Anggara Mahardika Anggara Mahardika Anggraeni, Novia Antonius Budi Susanto Arri Yuliantara Bambang Dwiloka Cristeddy Asa Bakti Cristeddy Asa Bakti Divina Elaine Purwanto Ferdy Semuel Rondonuwu Geraldus Tegar Mahardika Hapsari, Martina Widhi James Ngginak Jayanti Usman, Jienny Maria Yuliana Belaon Maria Yuliana Belaon Martina Widhi Hapsari Mohamad Padri Novia Anggraeni Novianingrum , Milka Putri Ocky Karna Radjasa Ocky Karna Radjasa Raka Bachtiar Kuspradanarto Ratih Paramastuti Rhema Alicia Rizkaprilisa, Windy Sia Clarissa Eleora Setiawan Silvia Nurvita, Silvia Walgiyanti, Immas Windy Rizkiprilisa