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Evaluasi Penggunaan Obat Antihipertensi pada Penyakit Hipertensi Disertai Gagal Ginjal Kronik (ICD I12.0) Pasien Geriatri Rawat Inap di RSUD A.W. Sjahranie Samarinda pada Tahun 2012 dan 2013 dengan Metode ATC/DDD Eko Yudha Prasetyo; Oetari Oetari; Tri Wijayanti
Jurnal Farmasi Indonesia Vol 12 No 1 (2015): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (746.126 KB) | DOI: 10.31001/jfi.v12i1.75

Abstract

Hypertension is a trigger factor of chronic kidney disease. This disease requires a special incentive treatment in geriatrics patient.The complexity of therapy forcing the use of polypharmachy teraphy. Evaluation needs to be done with the aim of knowing description the typeof antihypertensive drugs used and the quantity of its use based methods Defined Daily Dose (DDD) and suitability compared with Standar Pelayanan Medis (SPM) and the JNC 7. This study was a descriptive study with retrospective data collection. The sample was medical record data regarding the use of antihypertensive drugs in hypertension with chronic renal failure in geriatric patients (age≥ 60) hospitalization. The data collected includes classes and antihypertensive drug name, strength, frequency, duration of usage, length of stay. Then the data to be processed to determine the quantity of drug use in the ambulatory DDD and Drug Utilization (DU 90 %). The results of this study concluded that antihypertensive drugs included in the DU 90 % segment in 2012 were amlodipine (39.19%), furosemide (24.14%), captopril (14.14%), telmisartan (11.36%), valsartan (2.04%), and in 2013 were amlodipine (35.11%), furosemide (22.88%), captopril (18.80%), telmisartan (7.02%), valsartan (6.51%). Suitability based on SPM in 2012 (78.57%) and in 2013 (63.63%) and by the JNC 7 in 2012 (42.85) and 2013 (36,36%). There was no change in the pattern of use of antihypertensive drugs between 2012 and 2013.
EVALUASI PERENCANAAN KEBUTUHAN OBAT PUBLIK SERTA KETERSEDIAAN OBAT DI TINGKAT PUSKESMAS SE-WILAYAH KERJADINKES KOTA SURAKARTATAHUN 2015 Eko Yudha Prasetyo; Satibi .; Gunawan Pamudji Widodo
Jurnal Farmasi Indonesia Vol 13 No 2 (2016): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (658.166 KB) | DOI: 10.31001/jfi.v13i2.289

Abstract

Drug planning is an important aspect of drug management. Planning is aimed at determining the type and amount of drug in accordance with the needs of community helth center. Although the regulatory guideline of public drug management have been made, but still found the incidence of overstock and stockout. With these considerations it’s necessary to evaluate related planning processes and drug availability. The purpose of this study to know the planning process, the problems encountered and the level of drug availability in community health center throughout the whole working area of Surakarta Department of Health. This research is observational and evaluative study with qualitative approach, supported by quantitative data. Secondary data were obtained from the search document of drug plan for 2015, the usage and demand report of drug. The secondary data is processed to determine the accuracy of planning, the availability and suitability of drug demand. To strengthen information were conducted triangulation and interviews with drug manager related. The results showing the drug plan has not been efficient seen from an average accuracy of drug planning in treatment primary health centers is 440.5% and 389.98% at non-treatment primary health centers. The problems in planning isn’t optimal use of information management system based on electronically in providing data for drug planning, the procurement with e-purchasing requires time and administration are too long, the plan of medicine isn’t fully realized, the community health center received drug beyond the plan so that the use of drugs less effective, The average availability of drugs in the category of excess which amounted to 31.13 months in treatment health centers and 33.95 months in non-treatment.
Risiko Penggunaan ACEi Terhadap Kejadian Batuk Kering Pada Pasien Hipertensi Di Rumah Sakitaura Syifa Kediri Yogi Bhakti Marhenta; Krisogonus Ephrino Seran; Sandra elsamba; Eko Yudha Prasetyo; Wika Admaja
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 4 No 02 (2023): HERCLIPS VOL 04 NO 02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v4i02.5298

Abstract

Hipertensi yang dikenal sebagai silent killer merupakan salah satu penyumbang terbesar terjadinya penyakit lain seperti stroke dan penyakit jantung. Obat antihipertensi golongan angiotensin converting enzyme inhibitor (ACEi) dapat menyebabkan efek samping yaitu batuk kering. Penelitian ini bertujuan untuk mengetahui risiko kejadian batuk kering pada pasien hipertensi rawat jalan di poli jantung yang mendapatkan obat golongan ACEi di rumah sakit Aura Syifa Kediri. Penelitian ini merupakan penelitian kohort prospektif, observasi dilakukan dengan cara wawancara terstruktur pada pasien hipertensi rawat jalan di poli jantung. Kriteria inklusi adalah pasien hipertensi rawat jalan dipoli jantung yang berkunjung lebih dari satu kali yang mendapatkan terapi obat golongan ACEi (captopril 25 mg dan lisinopril 5 mg) dan mendapatkan terapi kombinasi serta bersedia diikutsertakan sebagai subjek penelitian. Data kejadian batuk kering dievaluasi menggunakan skala naranjo dan hasilnya dianalisis menggunakan uji chi square. Hasil penelitian menunjukkan bahwa kejadian batuk kering terjadi pada 12,2% subjek. Faktor usia, jenis kelamin dan lama penggunaan obat tidak berhubungan bermakna dengan kejadian batuk kering akibat penggunaan ACEi. Dengan hasil uji chi square hubungan batuk kering dengan jenis kelamin yaitu P sebesar 0,691, hubungan kejadian batuk kering dengan usia yaitu P sebesar 0,691 dan hubungan batuk kering terhadap lama penggunaan obat yaitu P sebesar 0,909. Tidak ada perbedaan bermakna kejadian batuk kering akibat penggunaan captopril dibandingkan lisinopril
FORMULASI DAN UJI AKTIVITAS SEDIAAN SAMPO EKSTRAK DAUN KERSEN (Muntingia calabura L.) SEBAGAI ANTIKETOMBE TERHADAP JAMUR Candida albicans SECARA IN VITRO Munifatul Lailiyah; Sony Andika Saputra; Eko Yudha Prasetyo; Dian Sri Lestrasi
JIFS: JURNAL ILMIAH FARMASI SIMPLISIA Vol. 2 No. 1 (2022): Juni 2022
Publisher : Jurusan Farmasi, Politeknik Kesehatan Kementerian Kesehatan Aceh

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Abstract

Ketombe merupakan suatu keadaan anomali pada kulit kepala dan salah satu penyebabnya ialah jamur Candida albicans. Daun kersen (Muntingia calabura L.) merupakan bahan alam yang mengandung senyawa antijamur, yaitu  flavonoid, saponin dan tanin. Penelitian ini bertujuan untuk membuat formulasi sediaan sampo antiketombe ekstrak daun kersen (Muntingia calabura L.) dengan tiga variasi konsentrasi yakni 5%, 10% dan 15% dan menguji pengaruh peningkatan konsentrasi ekstrak daun kersen pada sediaan sampo antiketombe terhadap aktivitas antijamur. Jenis penelitian ini ialah eksperimental. Hasil penelitian membuktikan bahwa ekstrak daun kersen (Muntingia calabura L.) dapat diformulasikan sebagai sediaan sampo antiketombe yang memenuhi persyaratan seperti organoleptik, pH dan tinggi busa. Uji aktivitas antijamur dilakukan dengan metode difusi sumuran untuk mengetahui efektivitas antijamur dengan mengamati daerah hambatan. Analisis data mengunakan uji ANOVA dan uji post hoc LSD (α=0,05). Berdasarkan hasil yang diperoleh F3 dengan konsentrasi ekstrak daun kersen 15% mempunyai aktivitas antijamur paling baik dibandingkan dengan F1 dengan konsentrasi ekstrak 5% dan F2 dengan konsentrasi ekstrak 10%.
Analysis Of Patient Perceptions, Awareness, Experience And Expectations Of The Role Of Pharmacist In Counseling Service At Pharmacies Dyah Ayu Kusumaratni; Eko Yudha Prasetyo; Indah Srihartini; Shofiatul Fajriyah; Widhi Astutik; Aprillia Putri G.R
Jurnal EduHealth Vol. 15 No. 02 (2024): Jurnal eduHealt, Edition April - June , 2024
Publisher : Sean Institute

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Abstract

Counseling services are a form of communication between pharmacists and patients in pharmaceutical services with the aim of increasing patient understanding of drug use and preventing medication errors. The presence of pharmacists is very necessary to be able to meet the diverse demands of society to be able to provide information regarding the correct use of medicines so that they can increase public knowledge. The interactions that occur between pharmacists and patients in counseling services will have an influence on public assessment. This research was conducted with the aim of knowing patients' perceptions, awareness, experiences and expectations of the role of pharmacists in counseling services in pharmacies. Method: The research is descriptive with a cross sectional design with a purposive sampling technique, the number of subjects involved was 143 respondents. Descriptive data analysis and normality test. Results: showed that 67.13% of patients had good awareness. As many as 53.14% of patients had a good perception. Then as many as 100% of patients had good hopes, and as many as 72.02% of patients had good experiences. Conclusion: the overall category shows the percentage of patients who have good perceptions, awareness, expectations and experiences regarding the role of pharmacists in counseling services in pharmacies.
Rationality Of Analgesic-Antipyretic Use In Dengue Hemorrhagic Fever Patients Indah Sri Hartini; Eko Yudha Prasetyo; Dyah Ayu Kusumaratni; Arshy Prodyanatasari
Jurnal EduHealth Vol. 14 No. 04 (2023): Jurnal eduHealt, 2023, December
Publisher : Sean Institute

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Abstract

Dengue haemorrhagic fever (DHF) is a disease caused by acute dengue virus infection transmitted through the bite of the Aedes Aegepty mosquito. Data from the health department states that the increase in the Case Fatality Rate (CFR) of DHF in 2020 is 0.8% and in 2021 is 1.1% while the national target is <1%. DHF patients need proper treatment to minimize the occurrence of contraindications in patients. DHF patients generally experience initial symptoms of sudden high fever >38oC, headache or pain behind the eyeball, muscle and bone pain. Treatment of DHF patients to reduce the pain experienced is by giving the right antipyretic analgesic. Based on this, the researcher wants to examine the description of the use of analgesic-antipyretics to determine the rationality level of the use of analgesic-antipyretics in DHF patients. The rationality of analgesic-antipyretic use measured, including patient accuracy, drug accuracy, indication accuracy, and dose accuracy. The type of research conducted was non-experimental observational research with retrospective data collection and the sampling technique used was totality sampling. Data collection was carried out based on patient medical record data in the period January-August 2022. In accordance with WHO guidelines and the National Guidelines for Health Services for Dengue management, the provision of analgesic-antipyretic drugs in accordance with the drug of choice is paracetamol. Based on the data obtained, there were 74 DHF patients with 57% female patients and 43 male patients, and 42% of patients were children. The rationality of analgesic-antipyretic use in DHF patients is known to be 100% right patient; 37.84 right drug; 100% right indication; and 98.65% right dose.