Article Per Year (5 Year)
p-Index From 2021 - 2026
2.57
P-Index
This Author published in this journals
All Journal Media Penelitian dan Pengembangan Kesehatan Journal of the Medical Sciences (Berkala Ilmu Kedokteran) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Kedokteran: Media Informasi Ilmu Kedokteran dan Kesehatan Proceeding ISETH (International Summit on Science, Technology, and Humanity) Academic Hospital Journal Neurona Indonesian Journal of Biomedicine and Clinical Sciences Sanus Medical Journal Indonesian Journal of Pharmacology and Therapy
Abdul Gofir
Department Of Neurology, Faculty Of Medicine, Public Health And Nursing, Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta,
Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 20 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search
Journal : Neurona

 1 
SKOR ISAN SEBAGAI PREDIKTOR IN-HOSPITAL MORTALITY PADA PASIEN DENGAN STROKE-ASSOCIATED PNEUMONIA Mara Ditta, Adist Azizy; Gofir, Abdul; Satiti, Sekar; Hanif, Faishal
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 40 No 2 (2024): Vol 40 No 2 (2024): Volume 40, No 2 - Maret 2024
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v40i2.497

Abstract

Introduction: Stroke-associated pneumonia (SAP) is attributed as the most common cause of death in acute stroke. ISAN score is a potential tool for predicting SAP in acute stroke care since it is easy to use. Several clinical risk such as age and pre-stroke disability has been proposed to contribute mortality in SAP patients. Aims: This study aims to determine the relationship between ISAN score and in-hospital mortality in acute stroke patients at RSUP Dr. Sardjito. Methods: This study is an analytic observational study with a retrospective cohort design using data from the stroke registry of the Stroke Unit of RSUP Dr. Sardjito from 2021 - 2023. Patients who were clinically diagnosed with SAP at the time of acute phase stroke treatment were included in the study. ISAN scores were divided into 0-5, 6-10, 11-14, and >14 with the interpretation of low, medium, high, and very high respectively. The data was analysed using SPSS v22.. Results: A total of 147 stroke patients with SAP (55% male, mean age 64.9 ± 13.4 years) were included in this study. Death occurred in 61 study subjects and was more prevalent in the high ISAN group (n=30). On bivariate analysis, mortality was significantly associated with ISAN score (p=0.002), gender (p=0.003) and NIHSS score (p=0.002). High ISAN scores have been associated with mortality of stroke patients with SAP, according to multivariate analysis. (aOR=3.94, IK95% 1.31-11.84, p=0.015). Discussion: A high ISAN score at admission is significantly associated with mortality of stroke patients with SAP. Keywords: Pneumonia, stroke, mortality, acute stroke, ISAN score
HUBUNGAN POLIMORFISME MTHFR c.677C>T DENGAN FUNGSI KOGNITIF PADA PASIEN STROKE ISKEMIK AKUT DI RSUP DR. SARDJITO Haq, Arinal; Gofir, Abdul; Ar Rochmah, Mawaddah; Amelia Nur Vidyanti; Yogik Onky Silvana Wijaya, Yogik Onky Silvana Wijaya
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 40 No 2 (2024): Vol 40 No 2 (2024): Volume 40, No 2 - Maret 2024
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v40i2.511

Abstract

Introduction: Ischemic stroke is an acute cerebrovascular event with cognitive impairment presents as its prevalent manifestation and complication. Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme in folate metabolism through an integral process of cellular metabolism in DNA, RNA and protein methylation. MTHFR c.677C>T polymorphism is considered an important genetic risk factor for stroke and cognitive dysfunction in some populations. Aim: This study aimed to investigate the association between the MTHFR c.677C>T polymorphism and cognitive function in acute ischemic stroke patients in Dr. Sardjito General Hospital Yogyakarta. Methods: We performed a cross-sectional study in 42 consecutive acute ischemic stroke patients. PCR R-FLP was used to examine MTHFR c.677C>T polymorphism. Cognitive function was determined using MoCA-Ina within 24 hours of each patient’s admission, with score 24 is the cut off for cognitive impairment. Results: Of 42 patients, 12 patients (28.6%) showed MTHFR c.677C>T variant. There were 3 patients (25%) with homozygous variant of MTHFR c.677C>T. Cognitive dysfunction was found in 7 patients (16.7%) with MTHFR c.677C>T variant and 18 patients (42.9%) with wild type MTHFR. However, no significant association was found between MTHFR c.677C>T with cognitive function in acute ischemic stroke patients (p=0.921). Discussion: The frequency of MTHFR c.677C>T polymorphism in this study was 28.6% with a quarter of them showing homozygous variant. There was no association between MTHFR c.677C>T polymorphism with cognitive function in acute ischemic stroke patients.
PERAN LABELATOL DALAM MANAJEMEN HIPERTENSI EMERGENSI PADA STROKE AKUT Setyopranoto, Ismail; Gofir, Abdul; Paryono
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 41 No 5: Edisi Suplemen Neurona Bekerjasama dengan JogjaCLAN 2025
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v41i5.862

Abstract

PENCEGAHAN PERBURUKAN PADA PENYAKIT PARKINSON: PENDEKATAN FARMAKOLOGIS DAN NON-FARMAKOLOGIS Subagya; Rohma, Novita Nur; Gofir, Abdul; Ar Rochmah, Mawaddah
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 41 No 5: Edisi Suplemen Neurona Bekerjasama dengan JogjaCLAN 2025
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v41i5.870

Abstract

Parkinson's disease (PD) is a complex neurodegenerative disorder with a progressive course. Most patients experience symptom deterioration over time, although the rate of progression varies between individuals. PD is the second most common neurodegenerative disease worldwide, with prevalence exceeding ~1% in people over 60 and ~5% in those over 85. Its incidence is rising globally with aging populations, and the number of PD cases is projected to double by 2040 compared to 2015. Despite significant advances in symptomatic treatments, no intervention has been proven to halt or reverse the underlying pathology of PD. This therapeutic gap underscores the importance of strategies aimed at preventing disease progression in order to preserve functional capacity and improve patients’ quality of life. This review provides an overview of the progressive nature of PD, current challenges in its management, and both pharmacological and non-pharmacological approaches aimed at preventing further deterioration. Keywords: Prevention, Parkinson’s disease, progressive, neurodegenerative
Co-Authors Amelia Nur Vidyanti Anton Darmawan Astuti Prodjohardjono Dini Khairunnisa Fatoni, Rismi Gea Pandhita S Hanif, Faishal Haq, Arinal Hemi Sinorita Hidayah Karuniawati Hiztien Fahrurriza Ika Puspitasari Ika Puspitasari Indera Indera Ismail Setyopranoto Ismail Setyopranoto Khairunnisa, Dini Mara Ditta, Adist Azizy Mawaddah Ar-Rochmah Mohammad Hakimi Mohammad Hakimi Mohammad Hakimi Mustofa Mustofa Mustofa Nadhilla, Nyimas Farisa Nathania, Caroline Evanthe Noor Alia Susanti Pandhita S, Gea Paryono Probosuseno Probosuseno Prodjohardjono, Astuti Rismi Fatoni Rohma, Novita Nur Rohmania Setiarini Samekto Wibowo Samekto Wibowo Samekto Wibowo Satiti, Sekar Sedjatiningsih, Wahyu Setyaningrum, Cempaka Thursina Srie Setyaningsih, Indarwati Setyawan, Tommy Rachmat Silalahi, Lothar Matheus Manson Vanende Siti Aisyah Affiati Siti Farida Sri Sutarni Sri Sutarni Subagya Sugiyanto - Sugiyanto Sugiyanto Susianti, Noor Alia Wahyu Sedjatiningsih Yogik Onky Silvana Wijaya Yudhanto Utomo Zullies Ikawati