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Journal : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Moringa oleifera Lam. to accelerate wound healing: a review Jaya, Fidi Bhawana; Syamsunarno, Mas Rizky Anggun Adipurna; Sahiratmadja, Edhyana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 55, No 3 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19106/JMedSci005503202310

Abstract

An injury to the skin that disrupts the soft tissue may form a wound. The healing process in response to injury is a dynamic and well-regulated process of cellular, humoral, and molecular mechanisms that consists of four partly overlapping phases: hemostasis, inflammation, proliferation, and remodeling. An impaired wound-healing process may cause a formation of an abnormal scar and chronic wounds, leading to a reduced life quality. Therefore, it needs an optimal prevention strategy. Many modalities have been claimed to accelerate wound healing. The trend of using natural products is increasing in most Southeast Asian countries due to their biodiversity. Nowadays, studies on natural compounds are increasing to accelerate wound healing. Moringa oleifera Lam. is a high-value plant that each part of it has a high nutritional value as well as a great range of medicinal uses, including anti-inflammatory, antimicrobial, antioxidant, and wound healing properties. In this review, we have explored the M. oleifera that are very rich in vitamins, minerals, fatty acids, and phytochemical compounds like quercetin, kaempferol, and vicenin-2, that play a role in the wound healing process. Moreover, these compounds may enhance the healing of wounds with pathological conditions such as diabetes, immunocompromised and persistent infection.
Co-Authors A, Muhammad Naufal Afandi Charles, Afandi Afifah, Nadya Nurul Aini, Intan Nur Akhmad Yogi Pramatirta, Akhmad Yogi Alfi, Mohammad Abyan Anandayu Pradita Anggraini Widjajakusuma, Anggraini Ani Melani Ani Melani Maskoen Ari indra Susanti Astuti, Intan Widya Aulia Bramantyo Azzahra, Fadhilla Zakya Bayu A. P. Wilopo, Bayu A. P. Bethy Suryawathy Hernowo Birgitta M. Dewayani, Birgitta M. Cynthia Kurniawan Dewantoro, Julius Broto Dewi, Vycke Yunivita Dhestina, Winnery Elsa Pudji Setiawati Elvina Karyadi Fadillah, Viki Faliq, Muhammad Faza Fitri Rahmi Fadhilah Gatot N.A. Winarno Gisrianti, Reina Syafira Gisrianti,, Reina Syafira Haryono Tansah, Haryono Helena Napitu, Helena Hendraswari, Chatrine Aprilia Herman Susanto Hudaya, Syahra Ramadhani Ikhwanuliman Putera Ikrar Syahmar Intan M. W. Dewi, Intan M. W. Jaya, Fidi Bhawana Julius Broto Dewanto, Julius Broto Kennardi, Gabriel Bagus Laniyati Hamijoyo, Laniyati Lelani Reniarti Lestari, Frida Dwi Maharani, Khalista Ismaya Mas Rizky A.A. Syamsunarno Melisa Intan Barliana, Melisa Intan Mugia Bayu Rahardja Mugia Bayu Raharja Muhammad Zulfikar Azhar, Muhammad Zulfikar Nabilah, Kayla Shafa Nagelkerke, Nico Ndaha Wungo, Sydney Immanuella Puteri Novi Vicahyani Utami Penggoam, Simeon Permatasari, Lany Indah Pramono, Alvinsyah Adhityo Pratama, Muhammad Syawal Prayudi Santoso Putra Sit, Ari Dwi Putri, Rahmania Devina R.M. Ryadi Fadil, R.M. Ryadi Rachmawati, Anita Ramdan Panigoro Ratu Safitri Rokhimawaty, Afita Ruswana Anwar Salsabila, Fathiyyah Samandari, Aquila Mozaffar Sari Puspa Dewi Shadrina, Siti Azyyati Nur SONY SUHANDONO Sulistiyorini, Ifa Sumantri, Nur Imaniati Sunarjati Sudigdoadi Surbakti, Indra Murty Tear, Alveron Andreas Tiyanto, Rizqi Deva Trevino A. Pakasi Tri Hanggono Achmad Viansih, Helsy Murtry Vita Murniati Tarawan Wijaya, Michelle Angelica Yuliasti Eka Purnamaningrum