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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Farmasi Andalas JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Farmasi Sains dan Komunitas JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Hilirisasi IPTEKS (JHI) JFIOnline Jurnal Ilmu Kefarmasian Indonesia Jurnal Farmasi Higea Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Pharmaceutical Sciences and Research (PSR) Journal of Public Health and Pharmacy
Dian Ayu Juwita
Fakultas Farmasi Universitas Andalas
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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Efek Ekstrak Etanol Kulit Batang Sirsak Terhadap Penurunan Kadar Gula Darah dan Kolesterol Dian Ayu Juwita; Husni Muchtar; Dolly Martha
Jurnal Sains Farmasi & Klinis Vol 2, No 1 (2015): J Sains Farm Klin 2(1), November 2015
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (491.069 KB) | DOI: 10.29208/jsfk.2015.2.1.44

Abstract

This study aims to determine effect of the ethanolic extract of soursop stembarks in the increasing of blood glucose and cholesterol levels. Maceration technique has been used to extract the soursop stembarks with ethanol 96% as a solvent extraction. Furthermore, the ethanolic extract of soursop stembarks was prepared in a suspension form with Na CMC 0.5 % as a suspending agent. The suspension was administered orally at dose of 50, 100, 300, 1000 mg/kg BW daily to white male mice for seven days. The level of blood sugar and cholesterol were measured at 8th day using digital tools Nesco®Multicheck. The result showed that the blood glucose level in mice at dose of 50, 100, 300, 1000 mg/KgBW were 123.25, 129.75, 132.25, 121.25 mg/dl. The cholesterol level mice at dose of 50, 100. 300, 1000 mg/kg BW were 156.5, 118.5, 149.75, 156.75 mg/dl respectively. Biostatistically, the ethanolic extract of soursop stembark showed the decreasing of cholesterol level significantly (p <0.05), but not significant to reduce the blood glucose level (p >0.05).
The comparison between combination of candesartan-amlodipine and candesartan-furosemide on blood pressure in hypertensive patients with chronic kidney disease Fitri Rachmaini; Dian Ayu Juwita; Almahdy A; Rahmad Abdillah; Yolanda Mayestika Wati
Pharmaciana Vol 12, No 2 (2022): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (446.191 KB) | DOI: 10.12928/pharmaciana.v12i2.21491

Abstract

Chronic renal disease is significantly increased by hypertension. Controlling blood pressure is critical in hypertensive individuals. Patients who have good blood pressure (BP) control can reduce morbidity and mortality. This study aimed to compare blood pressure reduction of candesartan-amlodipine with the candesartan-furosemide combination in hypertensive patients with chronic renal disease. The study was conducted by a cohort study design. Retrieval of medical record data was carried out prospectively during the period February-April 2019. The blood pressure reduction was assessed by changes in mean systolic and mean diastolic blood pressure and mean diastolic blood pressure and was analyzed statistically with the SPSS program. A total of 54 patients met the inclusion criteria, consisting of 27 patients receiving candesartan-amlodipine combination and 27 patients receiving candesartan-furosemide combination therapy. The results of the sociodemographic characteristics patients were male 30 patients (55.6%), age 56-65 years 24 patients (44.4%), senior high school education level 31 patients (57.4%). Candesartan-amlodipine and candesartan-furosemide combinations both decreased blood pressure in patients. However, the result of the statistical analysis revealed that there was no significant difference in blood pressure decline. (p> 0.05) between the two combinations.
Effect of Propolis on Bone Quality and Cortical Bone Thickness of Ovariectomized Female Wistar White Rats as A Model for Osteoporosis Juwita, Dian Ayu; Ahmadin, Almahdy; Rachmaini, Fitri; Abdillah, Rahmad; Fatma, Rosalia Medisa
Pharmaceutical Sciences and Research Vol. 8, No. 3
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Estrogen deficiency increases the rate of osteoporosis, especially in menopausal women, by altering the bone tissue microarchitecture. Propolis has compounds that could be used as an alternative therapy to treat estrogen deficiency and to protect against bone damage. This study aims to determine the effect of propolis on bone quality and cortical bone thickness of femoral metaphysis in ovariectomized female Wistar white rats as a model for menopausal osteoporosis. The rats were divided into five groups: negative control group (not subjected to ovariectomy), sham group (subjected to ovariectomy), and treatment groups that were subjected to ovariectomy and given propolis orally at a dose of 180 mg/kg BW, 360 mg/kg BW, and 720 mg/kg BW for 30 days. Bone quality and cortical bone thickness testing were undertaken on the 31st day. The osteoblast and osteoclast cell examination was evaluated using an Olympus BX 51 light microscope at 400x magnification for bone quality and the Betaview program, Beta 3.1MP Sony Exmor CMOS Sensor camera at 40x magnification for cortical bone thickness. Data were analyzed using the one-way ANOVA and continued with Duncan’s multiple range tests. It was found that propolis had a significant effect on the ratio of osteoblast and femur bone osteoclasts (p0.05). The administration of propolis at a dose of 180 mg/kg BW, 360 mg/kg BW, and 720 mg/kg BW had an effect in decreasing the ratio of osteoblasts and metaphysical osteoclast cells of femoral metaphysics. However, propolis administration did not affect the thickness of the femoral metaphysical cortical bone
The Effect of Medication Adherence and Asthma Control in Asthma Patients at a Public Health Center in Padang, Indonesia Dita Permatasari; Dian Ayu Juwita; Hesti Rachmawati Putri; Nurul Qalbi Desri
Jurnal Sains Farmasi & Klinis Vol 9 (2022): J Sains Farm Klin 9(suplemen), Desember 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.sup.190-195.2022

Abstract

Asthma is characterized by reversible swelling or narrowing of the airways. Low adherence can negatively affect the effectiveness of therapy, increasing asthma morbidity and mortality. The long-term goal of asthma treatment is to achieve and maintain controlled asthma, but this goal is still challenging for most patients. This study examines the relationship between medication adherence and asthma control in patients. This study is observational, with a cross-sectional approach conducted on 40 asthma patients who received treatment at a Public Health Center. Patient medication adherence was measured by Medication Possession Ratio (MPR) method, and the level of control was measured by the Asthma Control Test (ACT) questionnaire. The results showed that most patients based on sociodemographic characteristics were female (80.0%), elderly group ≥60 years (45.0%), high school education (55.0%), and housewives (45.0%). The category of medication adherence was divided into 47.5% adherent patients and 52.5% non-adherent patients. The level of patient control was divided into fully controlled (2.50%), partly controlled (35.0%), and uncontrolled (62.5%). There was a significant relationship between adherence and asthma control (r=0.508; p<0.05). Therefore, improving patient medication adherence can potentially improve asthma control levels.
Drugs Related Problems (DRPs) Pada Pasien Penyakit Ginjal Kronik (PGK) Di RSUP Dr. M. Djamil Dian Ayu Juwita; Fitri Rachmaini; Rahmad Abdillah; Meliani Meliani
Jurnal Sains Farmasi & Klinis Vol 9 (2022): J Sains Farm Klin 9(suplemen), Desember 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.sup.184-189.2022

Abstract

Penyakit Ginjal Kronis (PGK) ditandai dengan penurunan fungsi ginjal secara ireversibel yang dapat mempengaruhi proses eliminasi obat dari dalam tubuh. Drugs Related Problems (DRPs) merupakan suatu peristiwa terkait pengobatan bersifat aktual ataupun potensial yang dapat mempengaruhi hasil terapi pasien. Penelitian ini bertujuan untuk mengetahui persentase kejadian DRPs dan hubungan antara kejadian DRPs dengan kondisi pulang pasien didiagnosis PGK. Penelitian ini dilakukan secara retrospektif. Pengumpulan data dilakukan melalui rekam medis pasien pada tahun 2021. Analisis data dilakukan secara deskriptif dan uji korelasi Spearman Rank. Sebanyak 74 pasien memenuhi kriteria inklusi, terdiri dari 44 pasien laki-laki (59,46%) dan 30 pasien perempuan (40,54%). Rentang usia pasien PGK terbanyak adalah 46-55 tahun, yakni 22 pasien (29,73%). Ditemukan kejadian DRPs yakni indikasi tanpa terapi pada 7 pasien (35%), dosis obat kurang pada 1 pasien (5%), dan dosis obat berlebih pada 12 pasien (60%). Pada penelitian ini 67 orang pasien (90,54%) pulang dengan kondisi perbaikan, 5 orang pasien (6,76%) pulang dengan kondisi belum sembuh, dan 2 orang pasien (2,74%) meninggal. Dapat disimpulkan bahwa pada terdapat kejadian DRPs meliputi indikasi tanpa terapi, dosis obat kurang, dan dosis obat berlebih yang ditemukan pada pasien dengan Penyakit Ginjal Kronis (PGK) dalam penelitian ini. Tidak ada hubungan bermakna antara kejadian DRPs dengan kondisi pulang pasien (p>0,05).
Pengaruh Penggunaan Obat Antihipertensi Terhadap Tekanan Darah Dan Proteinuria Pada Pasien Preeklampsia Berat Di RSUP Dr. M. Djamil Fitri Rachmaini; Dian Ayu Juwita; Rahmad Abdillah; Melvi Auliya Rifqi
Jurnal Sains Farmasi & Klinis Vol 9 (2022): J Sains Farm Klin 9(suplemen), Desember 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.sup.175-183.2022

Abstract

Kondisi preeklampsia dapat berkembang menjadi eklampsia yang beresiko meningkatkan angka kematian bagi ibu dan janin. Obat antihipertensi dapat digunakan untuk pengobatan preeklampsia. Penelitian ini bertujuan mengetahui pengaruh penggunaan obat antihipertensi terhadap nilai tekanan darah dan proteinuria pasien didiagnosis preeklampsia berat. Metode yang digunakan adalah retrospektif cross-sectional. Pengumpulan data dilakukan melalui rekam medis dari Januari sampai Desember 2021. Data disajikan dalam 76 pasien memenuhi kriteria inklusi. Hasil penelitian menunjukkan terdapat 19 pasien (23%) menggunakan monoterapi antihipertensi metildopa atau nifedipin, 30 pasien (39,47%) menggunakan kombinasi metildopa dan nifedipin, dan empat pasien (5,26%) menggunakan kombinasi metildopa, nifedipin dan furosemide. Rata-rata penurunan tekanan darah sistolik dan diastolik (TDS/TDD) paling besar yaitu 85,25 mmHg dan 29,5 mmHg. Sedangkan rata-rata penurunan nilai proteinuria paling besar yaitu 2. Berdasarkan hasil tersebut diketahui bahwa terdapat pengaruh signifikan penggunaan obat antihipertensi terhadap TDS (p=0,000), TDD (p=0,000), dan nilai proteinuria (p=0,002). Penurunan nilai tekanan darah dan proteinuria lebih efektif terjadi pada terapi kombinasi dibandingkan dengan monoterapi.
PEMBUATAN DESINFEKTAN SEDERHANA MELALUI PEMANFATAAN BAHAN KARBOL DAN CAIRAN PEMUTIH PAKAIAN BAGI MASYARAKAT DI BALAI BARU KECAMATAN KURANJI KOTA PADANG Fitri Rachmaini; Dian Ayu Juwita; Rahmad Abdillah
Jurnal Hilirisasi IPTEKS Vol 6 No 2 (2023)
Publisher : LPPM Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jhi.v6i2.657

Abstract

One of the efforts to break the chain of transmission of Covid-19 is to maintain cleanliness using an antiseptic to wash hands and body parts, as well as disinfectants that are sprayed or rubbed on various inanimate objects that may be exposed to the virus. However, there are still many people who are mistaken about using antiseptics and disinfectants, such as using antiseptics to clean items and the phenomenon of massive spraying of disinfectants in various places, even directly on humans. Apart from that, the lack of skills in making simple disinfectant fluids independently is also one of the triggering factors for the low level of concern in protecting the surrounding environment. The purpose of this activity is to educate the public about the correct use of antiseptics and disinfectants and to be able to utilize carbolic acid and liquid bleach to become simple disinfectants. This activity was carried out in Balai Baru Village, Kuranji District, Padang City. The method used in this activity is the presentation of the principles of the proper use of disinfectants and antiseptics as well as direct demonstrations of making simple disinfectants. The results of the activity are increased public understanding of the proper use of disinfectants and antiseptics as well as increased community skills in utilizing carbolic acid and clothing bleach into simple disinfectants. This activity is expected to be a reference in making simple disinfectants that are economical, environmentally friendly, and can be made by anyone. It is hoped that the chain of transmission of Covid-19 can be minimized.
Peningkatan Pengetahuan Masyarakat tentang Penggunaan Obat yang Rasional melalui Edukasi Pengenalan Obat Dian Ayu Juwita; Elsa Badriyya; Lailaturrahmi Lailaturrahmi
Warta Pengabdian Andalas Vol 30 No 3 (2023)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.30.3.423-428.2023

Abstract

One of the factors influencing the level of drug usage is the level of knowledge. Knowledge is an essential aspect in shaping concrete actions. In society, various issues related to drug usage often arise due to a lack of understanding and incorrect behaviours regarding drug usage. Educating the public about the selection and rational use of drugs is compulsary cause of that. This activity was carried out on May 7, 2023, at Jondul Housing, Padang City. The education method employed was a lecture delivered to 35 participating mothers. This method has proven effective for all segments of society, regardless of their educational background. The general public showed high enthusiasm in participating and actively engaged in interactions, asking questions, and discussing with the speaker. The conclusion drawn from this activity is that education and outreach enhanced the public knowledge about the rational use of drugs.
Patient Satisfaction with Pharmaceutical Services at a Hospital Outpatient Pharmacy in West Sumatra, Indonesia Dian Ayu Juwita; Nurul Qalbi Desri; Dita Permatasari
JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Vol. 10 No. 3 (2023): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jfiki.v10i32023.324-330

Abstract

Background: Patient satisfaction stands as a metric for evaluating the quality of pharmaceutical services. The presence of community requests for high-quality pharmaceutical services has driven pharmacy personnel to enhance these services, aiming to establish patient satisfaction. Objective: The objective of this research is to assess the degree of patient satisfaction with pharmaceutical services in the outpatient pharmacy and to explore how this satisfaction is linked to the patients' sociodemographics. Methods: Conducted at Padang Panjang Hospital's Outpatient Pharmacy in West Sumatra, Indonesia, this descriptive research employed a questionnaire administered directly to patients. The method used involves a questionnaire consisting of 20 questions divided into two dimensions: Friendly Explanation (containing 11 questions) and Managing Therapy (containing nine questions). The questionnaire's validity (r > 0.632) and reliability (0.97). Data analysis was performed utilizing the Likert scale. Results: There were a total of respondents in this study (365 patients). Most of them (64.4%) were female, in the pre-elderly age group (45.2%), had completed high school (41.1%), and were housewives (31.8%). In general, the level of patient satisfaction is categorized as satisfied, with an average score of 3.49. Specifically, the "Friendly Explanation" got a score of 3.69, and the "Management of Therapy" got a score of 3.25. The study indicated notable statistical disparities in patient satisfaction levels based on age, education, and occupation (p<0.05), but gender did not have a significant impact (p>0.05). Conclusion: In summation, the study found that patients were satisfied with the pharmaceutical services at Padang Panjang Hospital's Outpatient Pharmacy.
Analysis of Pharmacists' Knowledge Level on Drug Management with The Availability of Medicine in Community Health Centers in Padang City Dian Ayu Juwita; Hansen Nasif; Ivana Regita Viviani
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 3 (2023): J Sains Farm Klin 10(3), Desember 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.3.307-313.2023

Abstract

The availability of medicine is one of the factors that can be employed to assess the quality of community health centers and determine customer satisfaction. Pharmacists require a strong foundation in drug management knowledge to ensure the medicine availability. Proficient drug management can enhance the rational use of medications, promote rational prescription practices, and improve drug utilization efficiency. This research aims to ascertain the pharmacist's knowledge level and the availability of medicine while also exploring any potential correlations between pharmacist knowledge and medicine availability. This research adopts a non-experimental study design with cross-sectional data collection. The research sample was selected using purposive sampling techniques, employing a questionnaire to assess pharmacist knowledge levels, as well as Drug Usage Reports and Drug Request Sheets (LPLPO) to evaluate the availability of medicine levels. Data analysis involved the Chi-Square test and Spearman Rank test. The study results indicated that the majority of pharmacists possessed a high level of knowledge (73.7%), while most community health centers have a moderate level of medicine availability (73.7%). The Spearman Rank test revealed no significant correlation between pharmacist knowledge levels and the availability of medicine.
Co-Authors Abdillah, Rahmad Afifah Machlaurin, Afifah Ahmadin, Almahdy Al Rizka, Nabila Almahdy A Almahdy Almahdy Almahdy Almahdy Deni Noviza Desri, Nurul Qalbi Dita Permatasari Dita Permatasari Dolly Martha Dwi Afrianti, Rezy Dwisari Dillasamola Elsa Badriyya Fatma Sri Wahyuni Fatma, Rosalia Medisa Fitri Rachmaini Fitri, Maharani Reskia Hansen Nasif Helmi Arifin Heni Pujiastuti Hesti Rachmawati Putri Husni Muchtar Ivana Regita Viviani Jaka Perdana Julio Fajar Rahmat Illahi Lailaturrahmi Lailaturrahmi Meliani Meliani Meliani, Meliani Melvi Auliya Rifqi Nadila Oktavia Nadila Oktavia Najmiatul Fitria Nelfa Yulianti Netty Suharti Nguyen, Thang Nurul Qalbi Desri Nurul Qalbi Desri Octy Aisyahharma Putri, Hesti Rachmawati Rachmaini, Fitri Rahmad Abdillah Rahmah Rahmah Rahmah Rahmah Rahmi Yosmar Rifqi, Melvi Auliya Risa Hestia Rizka Afdhila Rizka Afdila Roslinda Rasyid Sabarita, Najah Suhatri Suhatri Tesa Inmerka Alwi Wira Sanjaya Yolanda Mayestika Wati