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The Effect of Medication Adherence and Asthma Control in Asthma Patients at a Public Health Center in Padang, Indonesia Permatasari, Dita; Juwita, Dian Ayu; Putri, Hesti Rachmawati; Desri, Nurul Qalbi
JSFK (Jurnal Sains Farmasi & Klinis) Vol 9 (2022): J Sains Farm Klin 9(suplemen), Desember 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.sup.190-195.2022

Abstract

Asthma is characterized by reversible swelling or narrowing of the airways. Low adherence can negatively affect the effectiveness of therapy, increasing asthma morbidity and mortality. The long-term goal of asthma treatment is to achieve and maintain controlled asthma, but this goal is still challenging for most patients. This study examines the relationship between medication adherence and asthma control in patients. This study is observational, with a cross-sectional approach conducted on 40 asthma patients who received treatment at a Public Health Center. Patient medication adherence was measured by Medication Possession Ratio (MPR) method, and the level of control was measured by the Asthma Control Test (ACT) questionnaire. The results showed that most patients based on sociodemographic characteristics were female (80.0%), elderly group ≥60 years (45.0%), high school education (55.0%), and housewives (45.0%). The category of medication adherence was divided into 47.5% adherent patients and 52.5% non-adherent patients. The level of patient control was divided into fully controlled (2.50%), partly controlled (35.0%), and uncontrolled (62.5%). There was a significant relationship between adherence and asthma control (r=0.508; p<0.05). Therefore, improving patient medication adherence can potentially improve asthma control levels.
Pengaruh Penggunaan Obat Antihipertensi Terhadap Tekanan Darah Dan Proteinuria Pada Pasien Preeklampsia Berat Di RSUP Dr. M. Djamil Rachmaini, Fitri; Juwita, Dian Ayu; Abdillah, Rahmad; Rifqi, Melvi Auliya
JSFK (Jurnal Sains Farmasi & Klinis) Vol 9 (2022): J Sains Farm Klin 9(suplemen), Desember 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.sup.175-183.2022

Abstract

Kondisi preeklampsia dapat berkembang menjadi eklampsia yang beresiko meningkatkan angka kematian bagi ibu dan janin. Obat antihipertensi dapat digunakan untuk pengobatan preeklampsia. Penelitian ini bertujuan mengetahui pengaruh penggunaan obat antihipertensi terhadap nilai tekanan darah dan proteinuria pasien didiagnosis preeklampsia berat. Metode yang digunakan adalah retrospektif cross-sectional. Pengumpulan data dilakukan melalui rekam medis dari Januari sampai Desember 2021. Data disajikan dalam 76 pasien memenuhi kriteria inklusi. Hasil penelitian menunjukkan terdapat 19 pasien (23%) menggunakan monoterapi antihipertensi metildopa atau nifedipin, 30 pasien (39,47%) menggunakan kombinasi metildopa dan nifedipin, dan empat pasien (5,26%) menggunakan kombinasi metildopa, nifedipin dan furosemide. Rata-rata penurunan tekanan darah sistolik dan diastolik (TDS/TDD) paling besar yaitu 85,25 mmHg dan 29,5 mmHg. Sedangkan rata-rata penurunan nilai proteinuria paling besar yaitu 2. Berdasarkan hasil tersebut diketahui bahwa terdapat pengaruh signifikan penggunaan obat antihipertensi terhadap TDS (p=0,000), TDD (p=0,000), dan nilai proteinuria (p=0,002). Penurunan nilai tekanan darah dan proteinuria lebih efektif terjadi pada terapi kombinasi dibandingkan dengan monoterapi.
Drugs Related Problems (DRPs) Pada Pasien Penyakit Ginjal Kronik (PGK) Di RSUP Dr. M. Djamil Juwita, Dian Ayu; Rachmaini, Fitri; Abdillah, Rahmad; Meliani, Meliani
JSFK (Jurnal Sains Farmasi & Klinis) Vol 9 (2022): J Sains Farm Klin 9(suplemen), Desember 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.sup.184-189.2022

Abstract

Penyakit Ginjal Kronis (PGK) ditandai dengan penurunan fungsi ginjal secara ireversibel yang dapat mempengaruhi proses eliminasi obat dari dalam tubuh. Drugs Related Problems (DRPs) merupakan suatu peristiwa terkait pengobatan bersifat aktual ataupun potensial yang dapat mempengaruhi hasil terapi pasien. Penelitian ini bertujuan untuk mengetahui persentase kejadian DRPs dan hubungan antara kejadian DRPs dengan kondisi pulang pasien didiagnosis PGK. Penelitian ini dilakukan secara retrospektif. Pengumpulan data dilakukan melalui rekam medis pasien pada tahun 2021. Analisis data dilakukan secara deskriptif dan uji korelasi Spearman Rank. Sebanyak 74 pasien memenuhi kriteria inklusi, terdiri dari 44 pasien laki-laki (59,46%) dan 30 pasien perempuan (40,54%). Rentang usia pasien PGK terbanyak adalah 46-55 tahun, yakni 22 pasien (29,73%). Ditemukan kejadian DRPs yakni indikasi tanpa terapi pada 7 pasien (35%), dosis obat kurang pada 1 pasien (5%), dan dosis obat berlebih pada 12 pasien (60%). Pada penelitian ini 67 orang pasien (90,54%) pulang dengan kondisi perbaikan, 5 orang pasien (6,76%) pulang dengan kondisi belum sembuh, dan 2 orang pasien (2,74%) meninggal. Dapat disimpulkan bahwa pada terdapat kejadian DRPs meliputi indikasi tanpa terapi, dosis obat kurang, dan dosis obat berlebih yang ditemukan pada pasien dengan Penyakit Ginjal Kronis (PGK) dalam penelitian ini. Tidak ada hubungan bermakna antara kejadian DRPs dengan kondisi pulang pasien (p>0,05).
Comparative Economic and Clinical Utility of Adding Candesartan for Hypertension Management Fitria, Najmiatul; Nguyen, Thang; Machlaurin, Afifah; Al Rizka, Nabila; Ayu Juwita, Dian
JSFK (Jurnal Sains Farmasi & Klinis) Vol 11 No 2 (2024): J Sains Farm Klin 11(2), August 2024
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.11.2.111-117.2024

Abstract

Introduction: Antihypertensive drugs require high costs because they are used over a long period. Therefore, consideration is needed in drug selection requirements, effectiveness, and price. This study aimed to see the beneficial results of hypertension therapy and the non-medical costs incurred by patients using cost-utility analysis (CUA). Method: This research was a prospective study. The incremental Cost-Utility Ratio (ICUR) of antihypertensive treatment was calculated using cost-utility data obtained through EQ-5D-5L questionnaires from outpatients at Universitas Andalas Hospital in January- March 2023 who met the inclusion and exclusion criteria. The costs used were from a patient perspective, consisting of direct medical and non-medical costs. This study compared standard treatment (amlodipine) with the addition of candesartan. Results: The number of respondents in this study was 67, consisting of 23 respondents (34.33%) using amlodipine alone and 44 respondents (65.67%) using the amlodipine-candesartan combination. The ICUR value obtained was IDR7,318,674/QALY. The difference in the average utility value of the amlodipine-candesartan combination with amlodipine alone is -0.02, and the difference in cost is -IDR12,224. Based on the cost-utility diagram, the amlodipine-candesartan combination group is included in the southwest quadrant (quadrant III), which illustrates that the cost required for the amlodipine-candesartan combination group is lower than the cost of the amlodipine single treatment group and the outcome is also not better (slightly lower or the same). Conclusion: It was recommended to prioritize using amlodipine alone for hypertension management, as it provides similar outcomes to the amlodipine-candesartan combination while incurring lower costs.
PELATIHAN PEMBUATAN MINUMAN REMPAH DARI TANAMAN OBAT KELUARGA (TOGA) BAGI IBU-IBU DI KELURAHAN RAWANG SEBAGAI UPAYA MENINGKATKAN EKONOMI KELUARGA Juwita, Dian Ayu
Jurnal Hilirisasi IPTEKS Vol 7 No 4 (2024)
Publisher : LPPM (Lembaga Penelitian dan Pengabdian kepada Masyarakat) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jhi.v7i4.813

Abstract

Education on the Benefits of Drinking Milk as a Source of Protein and Calcium for Elementary School Students Dian Ayu Juwita; Nadila Oktavia; Rahmah Rahmah
Warta Pengabdian Andalas Vol 31 No 3 (2024)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.31.3.492-497.2024

Abstract

Optimal nutrition plays a crucial role in supporting the growth and development processes of children. One abundant and easily accessible source of nutrition is milk. The protein and calcium content in milk support bone formation, brain development, and various bodily functions. This community service activity aims to provide education to elementary school students about the benefits of milk as a nutritional source and to enhance milk consumption habits. Education is conducted through face-to-face interactions using lecture and discussion methods. The material is presented through PowerPoint presentations, videos, and the distribution of leaflets to the participants. To assess the success of the educational activities, pretests and posttests are conducted on the participants. The results of the educational activities show an increase in the average posttest scores compared to the pretest scores regarding the benefits of drinking milk. This indicates that the educational activities have successfully improved the participants' understanding of the importance of including milk in a healthy diet.
Knowledge and Attitudes towards Antibiotic Use among Non-Health Undergraduate Students at Andalas University Juwita, Dian Ayu; Almasdy, Dedy; Fitri, Maharani Reskia
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 1 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007052

Abstract

The knowledge and understanding of the community about antibiotic usage are crucial to avoid inaccuracies in drug utilization. Negative impacts that can arise include the occurrence of resistance and the reduction in antibiotic effectiveness. Students with non-health related educational backgrounds are among the parts of the community that have a limited grasp of issues related to antibiotic usage. The aim of this research is to assess the level of knowledge and attitudes of non-health related major students towards antibiotic usage. This study utilized a cross-sectional method with validated questionnaires. Inclusion criteria for this research were non-health undergraduate students at Andalas University who were willing to complete the questionnaire comprehensively. The obtained data were statistically analyzed using SPSS version 26. The research findings indicate that non-health related major students at Andalas University possess moderate knowledge (54.7%) while their attitudes tend to be positive (71.1%) towards antibiotic usage. A significant correlation between students' knowledge and attitudes towards antibiotic usage was found, with a p-value 0.05. There was no significant correlation found between students' sociodemographic characteristics (faculty, age, gender, presence of family members working in the healthcare field) and their knowledge level. However, concerning attitudes, factors that influence include gender and the presence of family members working in the healthcare field.
Pharmacist Recommendations for Non-Infectious Diarrhea Self-Medication: A Study in Padang, Indonesia Nasif, Hansen; Dillasamola, Dwisari; Sanjaya, Wira; Juwita, Dian Ayu
Journal of Public Health and Pharmacy Vol. 5 No. 2: JULY 2025
Publisher : Pusat Pengembangan Teknologi Informasi dan Jurnal Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jphp.v5i2.5854

Abstract

Introduction: Diarrhea is a condition where a person defecates with a soft or liquid stool consistency or even just water which can be accompanied by blood or foam with a frequency that is more frequent than usual in a day. Self-medication is an action taken by someone to treat themselves by recognizing the symptoms and illnesses felt, usually minor illnesses, then choosing drugs according to their wishes without going through a doctor's prescription. Methods: A descriptive study with cross-sectional approach to determine the recommended choice of diarrhea drugs without symptoms of infection for self-medication from pharmacies in Padang City, West Sumatra, Indonesia. Data were collected through proportional random sampling using the Slovin formula. From a total of 247 pharmacies in Padang City, data was collected from 38 pharmacies that had been proportioned in 11 sub-districts in Padang City. Participants in this study were pharmacists on duty at the pharmacy. Data were collected through structured interviews recorded by pharmacists in pharmacies with a single question, what drug do you give for self-medication to adult patients with mild diarrhea without symptoms of infection. Results: Drug recommendations from pharmacist in Padang City pharmacies are attapulgite, kaolin-pectin, activated carbon, loperamide, Oral Re-hydration Formula (ORS), zinc supplements, probiotics, and antacids. The drug recommendations given are in the form of single therapy and combination therapy. Assessment of recommendations that are said to be appropriate refers to the recommendations of Dipiro (2020), namely the provision of a single absorbent or absorbent plus ORS. The results of appropriate recommendations were obtained at 44.74% and those that were not appropriate were obtained at 55.26%. There is no statistically significant evidence to suggest a relationship between the education level of pharmacist and appropriate of the answer (p>0.05). Conclusion: There are still many mistakes made by pharmacists in recommending diarrhea drugs without symptoms of infection for self-medication in pharmacies.
Community Education on the Appropriate and Safe Use of Over-the-Counter and Pharmacy-Only Medicines Juwita, Dian Ayu; Rachmaini, Fitri; Rahmah, Rahmah; Sabarita, Najah
Warta Pengabdian Andalas Vol 32 No 3 (2025)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.32.3.264-271.2025

Abstract

The use of over-the-counter (OTC) and pharmacy-only medicines has significantly increased due to their easy accessibility and the growing trend of self-medication. However, improper use of these medicines can lead to adverse effects, drug interactions, and even resistance. This community service activity aimed to raise public awareness about the rational and safe use of medicines, particularly OTC and pharmacy-only medicines. The activity was conducted using participatory education methods, including the delivery of material on drug classifications, simulation of reading drug labels and understanding usage instructions, as well as interactive sessions such as Q&A and consultations with pharmacists. The evaluation was carried out using pre-test and post-test assessments to measure participants’ knowledge before and after the educational session. The results showed a significant improvement in participants’ knowledge regarding the identification of drug types, label reading, and proper usage instructions. Additionally, participants demonstrated increased awareness of the risks associated with improper medication use and the importance of consulting pharmacists before taking OTC or pharmacy-only medicines. This activity highlights the essential role of pharmacists in public health education and emphasizes the need for structured, interactive educational strategies to promote responsible self-medication practices. Collaboration between healthcare professionals and the community is key to ensuring the safe and appropriate use of non-prescription medicines
Hubungan Lama Perawatan dengan Outcome Tekanan Darah dan Proteinuria pada Preeklampsia Berat Annisadillah, Dwi; Rachmaini , Fitri; Juwita, Dian Ayu
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1076

Abstract

Severe preeclampsia is a major obstetric complication associated with maternal and perinatal morbidity and mortality. Hospitalization duration may influence clinical outcomes, including blood pressure and proteinuria, particularly in patients receiving antihypertensive therapy with nifedipine or methyldopa. This study aims to evaluate the association between the length of hospital stay and changes in systolic and diastolic blood pressure, as well as proteinuria, in patients with severe preeclampsia treated with nifedipine or methyldopa. This retrospective study reviewed medical records of patients diagnosed with severe preeclampsia and admitted to Dr. M. Djamil Central General Hospital, Padang, between January and December 2023. Patients were categorized into two groups based on hospitalization duration: <5 days and ≥5 days. All patients received monotherapy with either nifedipine or methyldopa. Data on patient demographics, clinical parameters, and hospitalization length were collected. Statistical analyses were performed using the independent t-test and the Mann–Whitney test, with a significance level of p<0.05. Of 60 patients included, 44 (73.3%) were hospitalized for ≥5 days, while 16 (26.7%) stayed <5 days. Patients with ≥5 days of hospitalization experienced a significantly greater reduction in systolic blood pressure (40.93 mmHg vs. 29.00 mmHg, p=0.025) and proteinuria (23.06 vs 33.20, p=0.031) compared to the <5-day group. No significant difference was observed in diastolic blood pressure reduction (p=0.128).